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Article

Aalto, AL; Mohan, AK; Schwintzer, L; Kupka, S; Kietz, C; Walczak, H; Broemer, M; (2018) M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila. Cell Death & Differentiation 10.1038/s41418-018-0164-x. (In press). Green open access
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Abbink, DA; Carlson, T; Mulder, M; De Winter, JCF; Aminravan, F; Gibo, TL; Boer, ER; (2018) A Topology of Shared Control Systems—Finding Common Ground in Diversity. IEEE Transactions on Human-Machine Systems , 48 (5) pp. 509-525. 10.1109/THMS.2018.2791570. Green open access
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Abbosh, C; Swanton, C; Birkbak, NJ; (2018) Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer. Annals of Oncology 10.1093/annonc/mdy017. (In press). Green open access
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Abbott, TEF; Fowler, AJ; Pelosi, P; de Abreu, MG; Moller, AM; Canet, J; Creagh-Brown, B; ... StEP-COMPAC Group, .; + view all (2018) A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. British Journal of Anaesthesia , 120 (5) pp. 1066-1079. 10.1016/j.bja.2018.02.007. Green open access
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Abdollah, MRA; Carter, TJ; Jones, C; Kalber, TL; Rajkumar, V; Tolner, B; Gruettner, C; ... Chester, KA; + view all (2018) Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles. ACS Nano , 12 (2) pp. 1156-1169. 10.1021/acsnano.7b06734. Green open access
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Abdul-Aziz, AM; Shafat, MS; Sun, Y; Marlein, CR; Piddock, RE; Robinson, SD; Edwards, DR; ... Rushworth, SA; + view all (2018) HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia. Oncogene , 37 (20) pp. 2676-2686. 10.1038/s41388-018-0151-1. Green open access
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Abduo, J; Sambrook, RJ; (2018) Longevity of ceramic onlays: A systematic review. Journal of Esthetic and Restorative Dentistry , 30 (3) pp. 193-215. 10.1111/jerd.12384. Green open access
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Abou-Alfa, G; Qin, S; Ryoo, B-Y; Lu, S-N; Yen, C-J; Feng, Y-H; Lim, HY; ... Chen, L-T; + view all (2018) Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma. Annals of Oncology , 29 (6) pp. 1402-1408. 10.1093/annonc/mdy101. Green open access
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Abou-Alfa, GK; Meyer, T; Cheng, A-L; El-Khoueiry, AB; Rimassa, L; Ryoo, B-Y; Cicin, I; ... Kelley, RK; + view all (2018) Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma. New England Journal of Medicine , 379 (1) pp. 54-63. 10.1056/NEJMoa1717002. Green open access
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Abro, A; Delicata, L-A; Vongsanim, S; Davenport, A; (2018) Differences in the prevalence of sarcopenia in peritoneal dialysis patients using hand grip strength and appendicular lean mass: depends upon guideline definitions. European Journal of Clinical Nutrition , 72 (7) pp. 993-999. 10.1038/s41430-018-0238-3. Green open access
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Abubakar, I; Drobniewski, F; Southern, J; Sitch, A; Jackson, C; Lipman, M; Deeks, J; ... PREDICT Study Team, .; + view all (2018) Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study. The Lancet Infectious Diseases , 18 (10) pp. 1077-1087. 10.1016/S1473-3099(18)30355-4. Green open access
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Abubakar, I; Gupta, RK; Rangaka, MX; Lipman, M; (2018) Update in Tuberculosis and Non-tuberculous Mycobacteria 2017. Am J Respir Crit Care Med , 197 (10) pp. 1248-1253. 10.1164/rccm.201801-0106UP. Green open access
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Abubakar, I; Lalvani, A; Southern, J; Sitch, A; Jackson, C; Onyimadu, O; Lipman, M; ... Drobniewski, F; + view all (2018) Two interferon gamma release assays for predicting active tuberculosis: the UK PREDICT TB prognostic test study. Health Technology Assessment , 22 (56) 10.3310/hta22560. Green open access
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Abubakar, I; Zumla, A; (2018) Universal health coverage for refugees and migrants in the twenty-first century. [Editorial comment]. BMC Medicine , 16 (216) 10.1186/s12916-018-1208-2. Green open access
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Abudhaise, H; Davidson, BR; DeMuylder, P; Luong, T; Fuller, B; (2018) Evolution of dynamic, biochemical, and morphological parameters in hypothermic machine perfusion of human livers: A proof-of-concept study. PLoS ONE , 13 (9) , Article e0203803. 10.1371/journal.pone.0203803. Green open access
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Adam, R; Karam, V; Cailliez, V; O Grady, JG; Mirza, D; Cherqui, D; Klempnauer, J; ... Duvoux, C; + view all (2018) 2018 annual report of the European Liver Transplant Registry (ELTR) – 50‐year evolution of liver transplantation. Transplant International 10.1111/tri.13358. (In press). Green open access
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Adams, D; Gonzalez-Duarte, A; O'Riordan, WD; Yang, C-C; Ueda, M; Kristen, AV; Tournev, I; ... Suhr, OB; + view all (2018) Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis. The New England Journal of Medicine , 379 (1) pp. 11-21. 10.1056/NEJMoa1716153. Green open access
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Adams, D; Hawkins, PN; Polydefkis, M; (2018) Oligonucleotide Drugs for Transthyretin Amyloidosis. New England Journal of Medicine , 379 (21) p. 2086. 10.1056/NEJMc1810994. Green open access
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Adams, R; Brown, E; Brown, L; Butler, R; Falk, S; Fisher, D; Kaplan, R; ... FOCUS4 Trial Investigators; + view all (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. The Lancet Gastroenterology & Hepatology , 3 (3) pp. 162-171. 10.1016/S2468-1253(17)30394-1. Green open access
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Adjogatse, E; Erskine, P; Wells, SA; Kelly, JM; Wilden, JD; Chan, AWE; Selwood, D; ... Cooper, JB; + view all (2018) Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallographica Section D: Structural Biology , 74 (9) pp. 861-876. 10.1107/S2059798318009208. Green open access
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Adler, S; Huscher, D; Siegert, E; Allanore, Y; Czirják, L; DelGaldo, F; Denton, CP; ... EUSTAR co-workers on behalf of the DeSScipher project research g; + view all (2018) Systemic sclerosis associated interstitial lung disease - individualized immunosuppressive therapy and course of lung function: results of the EUSTAR group. Arthritis Research & Therapy , 20 (1) , Article 17. 10.1186/s13075-018-1517-z. Green open access
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Adriani, M; Nytrova, P; Mbogning, C; Hässler, S; Medek, K; Jensen, PEH; CREEKE, P; ... The ABIRISK Consortium; + view all (2018) Monocyte NOTCH2 expression predicts interferon-beta immunogenicity in multiple sclerosis patients. JCI Insight , 3 (11) , Article e99274. 10.1172/jci.insight.99274. Green open access
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Agerbæk, MØ; Bang-Christensen, SR; Yang, M-H; Clausen, TM; Pereira, MA; Sharma, S; Ditlev, SB; ... Salanti, A; + view all (2018) The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner. Nature Communications , 9 (1) , Article 3279. 10.1038/s41467-018-05793-2. Green open access
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Aggio, D; Smith, L; Hamer, M; (2018) Early life cognitive function and health behaviours in late childhood: testing the neuroselection hypothesis. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH , 72 (1) pp. 41-46. 10.1136/jech-2017-208896. Green open access
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Aguiar, P; Azevedo, O; Pinto, R; Marino, J; Cardoso, C; Sousa, N; Cunha, D; ... Ducla Soares, JL; + view all (2018) Biomarkers of Myocardial Fibrosis: Revealing the Natural History of Fibrogenesis in Fabry Disease Cardiomyopathy. Journal of the American Heart Association , 7 (6) 10.1161/JAHA.117.007124. Green open access
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Ahmad, AJ; Parekh, S; Ashley, PF; (2018) Methods of space maintenance for premature loss of a primary molar: a review. European Archives of Paediatric Dentistry , 19 (5) pp. 311-320. 10.1007/s40368-018-0357-5. Green open access
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Ahsan, F; Gardner, QA; Rashid, N; Towers, GJ; Akhtar, M; (2018) Preventing the N-terminal processing of human interferon α-2b and its chimeric derivatives expressed in Escherichia coli. Bioorganic Chemistry , 76 pp. 294-302. 10.1016/j.bioorg.2017.11.016. Green open access
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Aied, A; Song, W; Wang, W; Baki, A; Sigen, A; (2018) 3D Bioprinting of stimuli-responsive polymers synthesised from DE-ATRP into soft tissue replicas. Bioprinting , 9 pp. 37-43. 10.1016/j.bprint.2018.02.002. Green open access
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Aimo, A; Buda, G; Fontana, M; Barison, A; Vergaro, G; Emdin, M; Merlini, G; (2018) Therapies for cardiac light chain amyloidosis: An update. International Journal of Cardiology , 271 pp. 152-160. 10.1016/j.ijcard.2018.05.018. Green open access
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Aisyah, DN; Shallcross, L; Hayward, A; Aldridge, RW; Hemming, S; Yates, S; Ferenando, G; ... Story, A; + view all (2018) Hepatitis C among Vulnerable Populations: A Seroprevalence Study of Homeless, People Who Inject Drugs and Prisoners in London. J Viral Hepat , 25 (11) pp. 1260-1269. 10.1111/jvh.12936. Green open access
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Aisyah, DN; Shallcross, L; Hully, AJ; O'Brien, A; Hayward, A; (2018) Assessing hepatitis C spontaneous clearance and understanding associated factors—A systematic review and meta‐analysis. Journal of Viral Hepatitis , 25 (6) pp. 680-698. 10.1111/jvh.12866. Green open access
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Ajjawi, R; Crampton, PES; Rees, CE; (2018) What really matters for successful research environments? A realist synthesis. Medical Education , 52 (9) pp. 936-950. 10.1111/medu.13643. Green open access
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Akbaraly, T; Würtz, P; Singh-Manoux, A; Shipley, MJ; Haapakoski, R; Lehto, M; Desrumaux, C; ... Kivimäki, M; + view all (2018) Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies. Scientific Reports , 8 , Article 8620. 10.1038/s41598-018-26441-1. Green open access
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Al Fararjeh, F; Mahmood, S; Tachtatzis, P; Yallop, D; Devereux, S; Patten, P; Agrawal, K; ... Kassam, S; + view all (2018) A retrospective analysis of post transplant lymphoproliferative disorder following liver transplantation. European Journal of Haematology , 100 (1) pp. 98-103. 10.1111/ejh.12988. Green open access
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Al Maskari, R; Hardege, I; Cleary, S; Figg, N; Li, Y; Siew, K; Khir, A; ... Yasmin; + view all (2018) Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness. European Journal of Human Genetics , 26 (11) pp. 1648-1657. 10.1038/s41431-018-0226-z. Green open access
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Al Shareef, Zainab; Kardooni, Hoda; Murillo-Garzón, Virginia; Domenici, Giacomo; Stylianakis, Emmanouil; Steel, Jennifer H; Rabano, Miriam; ... Kypta, Robert M; + view all (2018) Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1. Oncogene , 37 pp. 5305-5324. 10.1038/s41388-018-0294-0. Green open access
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Alani, H; Henty, J; Thompson, N; Jury, E; Ciurtin, C; (2018) Systematic review and meta-analysis of the epidemiology of polyautoimmunity in Sjögren’s syndrome (secondary Sjögren’s syndrome) focusing on autoimmune rheumatic diseases. Scandinavian Journal of Rheumatology , 47 (2) pp. 141-154. 10.1080/03009742.2017.1324909. Green open access
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Alberro, JA; Ballester, B; Deulofeu, P; Fabregas, R; Fraile, M; Gubern, JM; Janer, J; ... Llombart, HA; + view all (2018) Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials. The Lancet Oncology , 19 (1) pp. 27-39. 10.1016/S1470-2045(17)30777-5. Green open access
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Alberts, R; de Vries, EMG; Goode, EC; Jiang, X; Sampaziotis, F; Rombouts, K; Böttcher, K; ... Weersma, RK; + view all (2018) Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Gut , 67 (8) pp. 1517-1524. 10.1136/gutjnl-2016-313598. Green open access
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Aldaadaa, A; Al Qaysi, M; Georgiou, G; Ma Leeson, R; Knowles, JC; (2018) Physical properties and biocompatibility effects of doping SiO2 and TiO2 into phosphate-based glass for bone tissue engineering. Journal of Biomaterials Applications , 33 (2) pp. 271-280. 10.1177/0885328218788832. Green open access
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Aldaadaa, A; Owji, N; Knowles, J; (2018) Three-dimensional Printing in Maxillofacial Surgery: Hype versus Reality. Journal of Tissue Engineering , 9 pp. 1-5. 10.1177/2041731418770909. Green open access
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Aldridge, R; Hayward, A; Hemming, S; Yates, S; Ferenando, G; Possas, L; Garber, E; ... Story, A; + view all (2018) High prevalence of latent tuberculosis and blood borne virus infection in a homeless population. Thorax , 73 (6) pp. 557-564. 10.1136/thoraxjnl-2016-209579. Green open access
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Aleman-Dominguez, M; Ortega, Z; Monzon, M; Garzon, L; Ajami, S; Liu, C; (2018) Polycaprolactone–carboxymethyl cellulose composites for manufacturing porous scaffolds by material extrusion. Bio-Design and Manufacturing Journal , 1 (4) pp. 245-253. 10.1007/s42242-018-0024-z. Green open access
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Alexander, K; Cleland, J; (2018) Satisfying the hydra: the social imperative in medical school admissions. Medical Education , 52 (6) pp. 587-589. 10.1111/medu.13586. Green open access
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Alexandre, AR; Carreira, PL; Isenberg, DA; (2018) Very delayed lupus nephritis: a report of three cases and literature review. Lupus Sci Med , 5 (1) , Article e000241. 10.1136/lupus-2017-000241. Green open access
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Alexandrou, C; Al-Aqbi, SS; Higgins, JA; Boyle, W; Karmokar, A; Andreadi, C; Luo, J-L; ... Rufini, A; + view all (2018) Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes. Scientific Reports , 8 , Article 12096. 10.1038/s41598-018-30591-7. Green open access
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Ali, S; Yui, S; Muzslay, M; Wilson, APR; (2018) Test parameters for efficacy evaluations of aerial hydrogen peroxide decontamination systems. Journal of Hospital Infection , 98 (4) pp. 438-439. 10.1016/j.jhin.2017.09.011. Green open access
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Allan, M; Ourselin, S; Hawkes, DJ; Kelly, JD; Stoyanov, D; (2018) 3D Pose Estimation of Articulated Instruments in Robotic Minimally Invasive Surgery. IEEE Transactions on Medical Imaging , 37 (5) 10.1109/TMI.2018.2794439. Green open access
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Allanore, Y; Distler, O; Jagerschmidt, A; Illiano, S; Ledein, L; Boitier, E; Agueusop, I; ... Khanna, D; + view all (2018) Double-blind, Randomized, 8-week Placebo-controlled followed by a 16-week open label extension study, with the LPA1 receptor antagonist SAR100842 for Patients With Diffuse Cutaneous Systemic Sclerosis. Arthritis Rheumatology , 70 (10) pp. 1634-1643. 10.1002/art.40547. Green open access
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Allanore, Y; Distler, O; Matucci-Cerinic, M; Denton, CP; (2018) Review: Defining a Unified Vascular Phenotype in Systemic Sclerosis. Arthritis & Rheumatology , 70 (2) pp. 162-170. 10.1002/art.40377. Green open access
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Alles, SR; Garcia, E; Balasubramanyan, S; Jones, K; Tyson, JR; Joy, T; Snutch, TP; (2018) Peripheral nerve injury increases contribution of L-type calcium channels to synaptic transmission in spinal lamina II: Role of α2δ-1 subunits. Molecular Pain , 14 10.1177/1744806918765806. Green open access
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Alles, SRA; Smith, PA; (2018) Comparison of ex vivo and in vitro actions of gabapentin in superficial dorsal horn and the role of extra-spinal sites of drug action. Neuroscience Letters , 694 pp. 148-153. 10.1016/j.neulet.2018.11.050. Green open access
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Alles, SRA; Smith, PA; (2018) Etiology and Pharmacology of Neuropathic Pain. Pharmacol Reviews , 70 (2) pp. 315-347. 10.1124/pr.117.014399. Green open access
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Alrabeah, GO; Knowles, JC; Petridis, H; (2018) Reduction of Tribocorrosion Products When using the Platform-Switching Concept. Journal of Dental Research , 97 (9) pp. 995-1002. 10.1177/0022034518765751. Green open access
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Alrifai, D; Forster, MD; Janes, SM; (2018) Emerging resistance pathways in lung cancer: what has ROS-1 taught us? [Editorial comment]. Translational Lung Cancer Research , 7 (Suppl 1) S9-S12. 10.21037/tlcr.2017.11.13. Green open access
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Alshammasi, H; Buchanan, H; Ashley, P; (2018) Dentists' use of validated child dental anxiety measures in clinical practice: a mixed methods study. International Journal of Paediatric Dentistry , 28 (1) pp. 62-70. 10.1111/ipd.12302. Green open access
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Alshomer, F; Chaves, C; Kalaskar, D; (2018) Advances in Tendon and Ligament Tissue Engineering: Materials Perspective. Journal of Materials Science , 2018 , Article 9868151. 10.1155/2018/9868151. Green open access
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Alsoghier, A; Ni Riordain, R; Fedele, S; Porter, S; (2018) Web-based information on oral dysplasia and precancer of the mouth - Quality and readability. Oral Oncology , 82 pp. 69-74. 10.1016/j.oraloncology.2018.05.003. Green open access
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Alston, H; Burns, A; Davenport, A; (2018) Loss of Appendicular muscle mass in haemodialysis patients is associated with increased self-reported depression, anxiety and lower general health scores. Nephrology , 23 (6) pp. 546-551. 10.1111/nep.13075. Green open access
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Alsughayyir, J; Motallebzadeh, R; Pettigrew, GJ; (2018) Are donor lymphocytes a barrier to transplantation tolerance? Current Opinion in Organ Transplantation , 23 (1) pp. 90-96. 10.1097/MOT.0000000000000492. Green open access
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Alyousef, AA; Nihtyanova, S; Denton, C; Bosoni, P; Bellazzi, R; Tucker, A; (2018) Nearest Consensus Clustering Classification to Identify Subclasses and Predict Disease. Journal of Healthcare Informatics Research , 2 (4) pp. 402-422. 10.1007/s41666-018-0029-6. Green open access
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Amalia, RI; Davenport, A; (2018) Estimated dietary sodium intake in peritoneal dialysis patients using food frequency questionnaires and total urinary and peritoneal sodium losses and assessment of extracellular volumes. European Journal of Clinical Nutrition , 73 pp. 105-111. 10.1038/s41430-018-0259-y. Green open access
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Amin, S; Kingswood, JC; Bolton, PF; Elmslie, F; Gale, DP; Harland, C; Johnson, SR; ... O'Callaghan, FJ; + view all (2018) The UK guidelines for management and surveillance of Tuberous Sclerosis Complex. QJM: An International Journal of Medicine , Article hcy215. 10.1093/qjmed/hcy215. Green open access
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Amos, R; Bulbeck, H; Burnet, N; Crellin, A; Eaton, D; Evans, P; Hall, E; ... Sharma, RA; + view all (2018) Proton Beam Therapy – the Challenges of Delivering High-quality Evidence of Clinical Benefit. Clinical Oncology , 30 (5) 10.1016/j.clon.2018.02.031. Green open access
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An, Z; Akily, B; Sabalic, M; Zong, G; Chai, Y; Sharpe, PT; (2018) Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor. Cell Reports , 23 (10) pp. 3102-3111. 10.1016/j.celrep.2018.05.001. Green open access
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An, Z; Sabalic, M; Bloomquist, RF; Fowler, TE; Streelman, T; Sharpe, PT; (2018) A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors. Nature Communications , 9 , Article 378. 10.1038/s41467-017-02785-6. Green open access
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Anderson, KL; O'Neill, DG; Brodbelt, DC; Church, DB; Meeson, RL; Sargan, D; Summers, JF; ... Collins, LM; + view all (2018) Prevalence, duration and risk factors for appendicular osteoarthritis in a UK dog population under primary veterinary care. Scientific Reports , 8 , Article 5641. 10.1038/s41598-018-23940-z. Green open access
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Anderson, ND; de Borja, R; Young, MD; Fuligni, F; Rosic, A; Roberts, ND; Hajjar, S; ... Shlien, A; + view all (2018) Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors. Science , 361 (6405) 10.1126/science.aam8419. Green open access
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Anderson, RA; Remedios, R; Kirkwood, AA; Patrick, P; Stevens, L; Clifton-Hadley, L; Roberts, T; ... Johnson, PWM; + view all (2018) Determinants of Ovarian Function After Response-adapted Therapy in Patients With Advanced Hodgkin's Lymphoma (RATHL): a Secondary Analysis of a Randomised Phase 3 Trial. Lancet Oncology , 19 (10) pp. 1328-1337. 10.1016/S1470-2045(18)30500-X. Green open access
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Andresen, V; Banerji, V; Hall, G; Lass, A; Emmanuel, AV; (2018) The patient burden of opioid-induced constipation: New insights from a large, multinational survey in five European countries. United European Gastroenterology Journal , 6 (8) pp. 1254-1266. 10.1177/2050640618786145. Green open access
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Ang, R; Mastitskaya, S; Hosford, PS; Basalay, M; Specterman, M; Aziz, Q; Li, Y; ... Gourine, AV; + view all (2018) Modulation of Cardiac Ventricular Excitability by GLP-1 (Glucagon-Like Peptide-1). Circulation: Arrhythmia and Electrophysiology , 11 (10) , Article e006740. 10.1161/CIRCEP.118.006740. Green open access
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Aravinthan, AD; Alexander, GJ; (2018) Telomere, telomerase and liver disease. Liver International , 38 (1) pp. 33-34. 10.1111/liv.13630. Green open access
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Arbore, G; West, EE; Rahman, J; Le Friec, G; Niyonzima, N; Pirooznia, M; Tunc, I; ... Kemper, C; + view all (2018) Complement receptor CD46 co-stimulates optimal human CD8(+) T cell effector function via fatty acid metabolism. Nature Communications , 9 , Article 4186. 10.1038/s41467-018-06706-z. Green open access
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Arends, M; Biegstraaten, M; Wanner, C; Sirrs, S; Mehta, A; Elliott, PM; Oder, D; ... Hollak, CEM; + view all (2018) Agalsidase alfa versus agalsidase beta for the treatment of Fabry disease: an international cohort study. Journal of Medical Genetics , 55 (5) pp. 351-358. 10.1136/jmedgenet-2017-104863. Green open access
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Aringer, M; Denton, CP; (2018) Systemic sclerosis phase III clinical trials: Hope on the horizon? Journal of Scleroderma and Related Disorders , 3 (3) pp. 193-200. 10.1177/2397198318775353. Green open access
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Arkenau, H-T; Italiano, A; Mak, G; Toulmonde, M; Baird, RD; Garcia-Corbacho, J; Plummer, R; ... Spicer, J; + view all (2018) An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours. European Journal of Cancer , 103 pp. 17-23. 10.1016/j.ejca.2018.07.134. Green open access
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Arnold, MB; Khanna, D; Denton, CP; van Laar, JM; Frech, TM; Anderson, ME; Baron, M; ... Pope, JE; + view all (2018) Patient acceptable symptom state in scleroderma: results from the tocilizumab compared with placebo trial in active diffuse cutaneous systemic sclerosis. Rheumatology , 57 (1) pp. 152-157. 10.1093/rheumatology/kex396. Green open access
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Arrigo, M; Von Moos, S; Gerritsen, K; Sadoune, M; Tangvoraphonkchai, K; Davenport, A; Mebazaa, A; ... Cippa, PE; + view all (2018) Soluble CD146 and B-type natriuretic peptide dissect overhydration into functional components of prognostic relevance in haemodialysis patients. Nephrology Dialysis Transplantation , 33 (11) pp. 2035-2042. 10.1093/ndt/gfy113. Green open access
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Arthur, VL; Shuldiner, E; Remmers, EF; Hinks, A; Grom, AA; Foell, D; Martini, A; ... Ombrello, MJ; + view all (2018) IL1RN Variation Influences both Disease Susceptibility and Response to Human Recombinant IL-1RA Therapy in Systemic Juvenile Idiopathic Arthritis. Arthritis & Rheumatology , 70 (8) pp. 1319-1330. 10.1002/art.40498. Green open access
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Arulkumaran, N; McLaren, CS; Arulkumaran, K; Philips, BJ; Cecconi, M; (2018) An analysis of emergency tracheal intubations in critically ill patients by critical care trainees. Journal of the Intensive Care Society , 19 (3) pp. 180-187. 10.1177/1751143717749686. Green open access
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Arulkumaran, N; Pollen, S; Greco, E; Courtneidge, H; Hall, AM; Duchen, MR; Tam, FWK; ... Singer, M; + view all (2018) Renal Tubular Cell Mitochondrial Dysfunction Occurs Despite Preserved Renal Oxygen Delivery in Experimental Septic Acute Kidney Injury. Critical Care Medicine , 46 (4) e318-e325. 10.1097/CCM.0000000000002937. Green open access
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Arulkumaran, N; Sixma, ML; Pollen, S; Ceravola, E; Jentho, E; Prendecki, M; Bass, PS; ... Singer, M; + view all (2018) P2X7receptor antagonism ameliorates renal dysfunction in a rat model of sepsis. Physiological Reports , 6 (5) , Article e13622. 10.14814/phy2.13622. Green open access
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Asadi, H; Martin, D; McKenna, H; (2018) Tackling delirium: a crucial target for improving clinical outcomes. British Journal of Hospital Medicine , 79 (3) pp. 132-135. 10.12968/hmed.2018.79.3.132. Green open access
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Ashaye, T; Hounsome, N; Carnes, D; Taylor, SJC; Homer, K; Eldridge, S; Spencer, A; ... COPERS Study Team (ISRCTN 24426731); + view all (2018) Opioid prescribing for chronic musculoskeletal pain in UK primary care: results from a cohort analysis of the COPERS trial. BMJ Open , 8 (6) , Article e019491. 10.1136/bmjopen-2017-019491. Green open access
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Ashley, PF; Chaudhary, M; Lourenço-Matharu, L; (2018) Sedation of children undergoing dental treatment. Cochrane Database of Systematic Reviews , 12 , Article CD003877. 10.1002/14651858.CD003877.pub5. Green open access
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Ashton, E; Legrand, A; Benoit, V; Roncelin, I; Venisse, A; Zennaro, MC; Jeunemaitre, X; ... Bockenhauer, D; + view all (2018) Simultaneous sequencing of 37 genes identified causative mutations in the majority of children with renal tubulopathies. Kidney International , 93 (4) pp. 961-967. 10.1016/j.kint.2017.10.016. Green open access
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ASiT/BOTA Lost Tribe Study Group, .; (2018) Early years postgraduate surgical training programmes in the UK are failing to meet national quality standards: An analysis from the ASiT/BOTA Lost Tribe prospective cohort study of 2,569 surgical trainees. International Journal of Surgery , 52 pp. 376-382. 10.1016/j.ijsu.2017.09.074. Green open access
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Atkinson, SR; McQuillin, A; Morgan, MY; Thursz, MR; (2018) People who survive an episode of severe alcoholic hepatitis should be advised to maintain total abstinence from alcohol. Hepatology , 67 (6) pp. 2479-2480. 10.1002/hep.29825. Green open access
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Atkinson, SR; Way, MJ; McQuillin, A; Morgan, MY; Thursz, MR; (2018) Reply to: "The PNPLA3 SNP rs738409:G allele is associated with increased liver disease-associated mortality but reduced overall mortality in a population-based cohort". Journal of Hepatology , 68 (4) pp. 860-862. 10.1016/j.jhep.2017.12.005. Green open access
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Attaf, M; Malik, A; Severinsen, MC; Roider, J; Ogongo, P; Buus, S; Ndung'u, T; ... Goulder, P; + view all (2018) Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells. Frontiers in Immunology , 9 , Article 2539. 10.3389/fimmu.2018.02539. Green open access
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Backen, AC; Lopes, A; Wasan, H; Palmer, DH; Duggan, M; Cunningham, D; Anthoney, A; ... Valle, JW; + view all (2018) Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial. British Journal of Cancer , 119 pp. 27-35. 10.1038/s41416-018-0132-8. Green open access
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Bageghni, SA; Hemmings, KE; Zava, N; Denton, CP; Porter, KE; Ainscough, JFX; Drinkhill, MJ; (2018) Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism. FASEB Journal , 32 (9) pp. 4941-4954. 10.1096/fj.201701455RR. Green open access
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Baisley, K; Chimbindi, N; Mthiyane, N; Floyd, S; McGrath, N; Pillay, D; Seeley, J; ... Shahmanesh, M; + view all (2018) High HIV incidence and low uptake of HIV prevention services: The context of risk for young male adults prior to DREAMS in rural KwaZulu-Natal, South Africa. PLoS One , 13 (12) , Article e0208689. 10.1371/journal.pone.0208689. Green open access
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Baker, A-M; Cross, W; Curtius, K; Al Bakir, I; Choi, C-HR; Davis, HL; Temko, D; ... Graham, TA; + view all (2018) Evolutionary history of human colitis-associated colorectal cancer. Gut 10.1136/gutjnl-2018-316191. Green open access
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Bakhoum, SF; Ngo, B; Laughney, AM; Cavallo, J-A; Murphy, CJ; Ly, P; Shah, P; ... Cantley, LC; + view all (2018) Chromosomal instability drives metastasis through a cytosolic DNA response. Nature , 553 (7689) pp. 467-472. 10.1038/nature25432. Green open access
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Bakshi, J; Segura, BT; Wincup, C; Rahman, A; (2018) Unmet Needs in the Pathogenesis and Treatment of Systemic Lupus Erythematosus. Clinical Reviews in Allergy & Immunology , 55 (3) pp. 352-367. 10.1007/s12016-017-8640-5. Green open access
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Bale, G; Rajaram, A; Kewin, M; Morrison, L; Bainbridge, A; Diop, M; St Lawrence, K; (2018) Broadband NIRS Cerebral Cytochrome-C-Oxidase Response to Anoxia Before and After Hypoxic-Ischaemic Injury in Piglets. Advances in Experimental Medicine and Biology , 1072 pp. 151-156. 10.1007/978-3-319-91287-5_24. Green open access
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Bangash, MA; Alles, SRA; Santana-Varela, S; Millet, Q; Sikandar, S; de Clauser, L; Ter Heegde, F; ... Wood, JN; + view all (2018) Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions. Wellcome Open Research , 3 , Article 78. 10.12688/wellcomeopenres.14641.1. Green open access
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Baraniak, IA; Kropff, B; Pichon, S; McLean, G; Milne, RSB; Smith, C; Mach, M; ... Reeves, M; + view all (2018) Epitope-specific humoral responses to human cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in seropositive solid organ transplant recipients: anti-AD2 levels correlate with protection from viraemia. Journal of Infectious Diseases , 217 (12) pp. 1907-1917. 10.1093/infdis/jiy102. Green open access
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Barata, PC; De Liano, AG; Mendiratta, P; Crolley, V; Szabados, B; Morrison, L; Wood, L; ... Rini, BI; + view all (2018) The efficacy of VEGFR TKI therapy after progression on immune combination therapy in metastatic renal cell carcinoma. British Journal of Cancer , 119 (2) pp. 160-163. 10.1038/s41416-018-0104-z. Green open access
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Barber, MRW; Hanly, JG; Su, L; Urowitz, MB; Pierre, YS; Romero-Diaz, J; Gordon, C; ... Clarke, AE; + view all (2018) Economic Evaluation of Lupus Nephritis in the Systemic Lupus International Collaborating Clinics Inception Cohort Using a Multistate Model Approach. Arthritis Care & Research , 70 (9) pp. 1294-1302. 10.1002/acr.23480. Green open access
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Barcella, W; Iorio, MD; Malone-Lee, J; (2018) Modelling correlated binary variables: An application to lower urinary tract symptoms. Journal of the Royal Statistical Society. Series C: Applied Statistics , 67 (4) pp. 1083-1100. 10.1111/rssc.12268. Green open access
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Barnes, KS; Smeed, B; Taylor, R; Hood, V; Brooke-Wavell, K; Slee, A; Ryg, J; (2018) The prevalence of sarcopenia in fallers and those at risk of falls in a secondary care falls unit as measured by bioimpedance analysis. Journal of Frailty, Sarcopenia and Falls , 3 (3) pp. 128-131. 10.22540/jfsf-03-128. Green open access
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Barton, M; Little, HJ; Vaughan-Jones, RD; Daniels, S; Dashwood, MR; Tsui, JC; (2018) In Memoriam: Sidney George Shaw, DPhil (1948-2017). Physiological Research , 67 S27-S35. Green open access
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Basnett, P; Marcello, E; Lukasiewicz, B; Panchal, B; Nigmatullin, R; Knowles, JC; Roy, I; (2018) Biosynthesis and characterization of a novel, biocompatible medium chain length polyhydroxyalkanoate by Pseudomonas mendocina CH50 using coconut oil as the carbon source. Journal of Materials Science: Materials in Medicine , 29 , Article 179. 10.1007/s10856-018-6183-9. Green open access
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Bathgate, G; Karra, E; Khoo, B; (2018) New Diagnosis of Hyperthyroidism in Primary Care. BMJ , 362 , Article k2880. 10.1136/bmj.k2880. Green open access
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Bedi, P; Chalmers, JD; Goeminne, PC; Mai, C; Saravanamuthu, P; Velu, PP; Cartlidge, MK; ... Hill, AT; + view all (2018) The BRICS (Bronchiectasis Radiologically Indexed CT Score): A Multicenter Study Score for Use in Idiopathic and Postinfective Bronchiectasis. Chest , 153 (5) pp. 1177-1186. 10.1016/j.chest.2017.11.033. Green open access
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Beever, LJ; Giles, K; Meeson, RL; (2018) Postoperative Complications Associated with External Skeletal Fixators in Dogs. VCOT - Veterinary and Comparative Orthopaedics and Traumatology , 31 (2) pp. 137-143. 10.1055/s-0038-1627477. Green open access
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Beilin, C; Choudhuri, K; Bouma, G; Malinova, D; Llodra, J; Stokes, D; Shimaoka, M; ... Burns, S; + view all (2018) Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse [version 1]. Wellcome Open Research 10.12688/wellcomeopenres.14493.1. Green open access
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Bell, JA; Carslake, D; O'Keeffe, LM; Frysz, M; Howe, LD; Hamer, M; Wade, KH; ... Davey Smith, G; + view all (2018) Associations of Body Mass and Fat Indexes With Cardiometabolic Traits. Journal of the American College of Cardiology , 72 (24) pp. 3142-3154. 10.1016/j.jacc.2018.09.066. Green open access
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Bell, JA; Hamer, M; Richmond, RC; Timpson, NJ; Carslake, D; Davey Smith, G; (2018) Associations of device-measured physical activity across adolescence with metabolic traits: Prospective cohort study. PLoS Med , 15 (9) , Article e1002649. 10.1371/journal.pmed.1002649. Green open access
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Bell, LCK; Noursadeghi, M; (2018) Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection. [Review]. Nature Reviews Microbiology , 16 (2) pp. 80-90. 10.1038/nrmicro.2017.128. Green open access
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Benmassaoud, A; Tsochatzis, EA; (2018) Loco-regional treatments on the liver transplant waiting list: unmasking hepatocellular carcinoma (HCC) biology. [Editorial comment]. Hepatobiliary Surgery and Nutrition , 7 (3) pp. 199-201. 10.21037/hbsn.2018.02.03. Green open access
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Benson, EE; Harding, K; Ryan, M; Petrenko, A; Petrenko, Y; Fuller, B; (2018) Alginate encapsulation to enhance biopreservation scope and success: a multidisciplinary review of current ideas and applications in cryopreservation and non-freezing storage. Cryoletters , 39 (1) pp. 14-38. Green open access
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Bergiers, S; Hothi, HS; Henckel, J; Eskelinen, A; Skinner, J; Hart, A; (2018) Wear performance of retrieved metal-on-metal Pinnacle hip arthroplasties implanted before and after 2007. Bone & Joint Research , 7 (11) pp. 595-600. 10.1302/2046-3758.711.BJR-2018-0143.R1. Green open access
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Bernatsky, S; Ramsey-Goldman, R; Petri, M; Urowitz, MB; Gladman, DD; Fortin, PR; Yelin, EH; ... Clarke, AE; + view all (2018) Smoking Is the Most Significant Modifiable Lung Cancer Risk Factor in Systemic Lupus Erythematosus. The Journal of Rheumatology , 45 (3) pp. 393-396. 10.3899/jrheum.170652. Green open access
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Berry, V; Ionides, ACW; Pontikos, N; Moghul, I; Moore, AT; Cheetham, ME; Michaelides, M; (2018) Whole-genome sequencing reveals a recurrent missense mutation in the Connexin 46 (GJA3) gene causing autosomal-dominant lamellar cataract. Eye , 32 pp. 1661-1668. 10.1038/s41433-018-0154-8. Green open access
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Best, LM; Takwoingi, Y; Siddique, S; Selladurai, A; Gandhi, A; Low, B; Yaghoobi, M; (2018) Non-invasive diagnostic tests for Helicobacter pylori infection. Cochrane Database Syst Rev , 3 , Article CD012080. 10.1002/14651858.CD012080.pub2. Green open access
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Best, LMJ; Freeman, S; Sutton, AJ; Hawkins, N; Tsochatzis, E; Gurusamy, KS; (2018) Treatment for hepatorenal syndrome in people with decompensated liver cirrhosis: A network meta-analysis. Cochrane Database of Systematic Reviews , 2018 (9) 10.1002/14651858.CD013103. Green open access
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Bhar-Amato, J; Finlay, M; Santos, D; Orini, M; Chaubey, S; Vyas, V; Taggart, P; ... Lambiase, PD; + view all (2018) Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome. Circulation: Arrhythmia and Electrophysiology , 11 (9) 10.1161/CIRCEP.118.006330. Green open access
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Bharucha, T; Sengvilaipaseuth, O; Vongsouvath, M; Vongsouvath, M; Davong, V; Panyanouvong, P; Piorkowski, G; ... Dubot-Pérès, A; + view all (2018) Development of an improved RT-qPCR Assay for detection of Japanese encephalitis virus (JEV) RNA including a systematic review and comprehensive comparison with published methods. PLoS One , 13 (3) , Article e0194412. 10.1371/journal.pone.0194412. Green open access
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Bhogal, AS; Montagnese, S; Mani, AR; (2018) The consideration of heart rate complexity as a co-morbidity factor for liver transplantation selection procedures. [Letter]. Liver International , 38 (2) p. 380. 10.1111/liv.13621. Green open access
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Biegstraaten, M; Cox, TM; Belmatoug, N; Berger, MG; Collin-Histed, T; Vom Dahl, S; Di Rocco, M; ... Hollak, CE; + view all (2018) Management goals for type 1 Gaucher disease: An expert consensus document from the European working group on Gaucher disease. Blood Cells, Molecules, and Diseases , 68 pp. 203-208. 10.1016/j.bcmd.2016.10.008. Green open access
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Bion, V; Lowe, AS; Puthucheary, Z; Montgomery, H; (2018) Reducing sound and light exposure to improve sleep on the adult intensive care unit: An inclusive narrative review. Journal of the Intensive Care Society , 19 (2) pp. 138-146. 10.1177/1751143717740803. Green open access
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Bird, TG; Müller, M; Boulter, L; Vincent, DF; Ridgway, RA; Lopez-Guadamillas, E; Lu, W-Y; ... Forbes, SJ; + view all (2018) TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Science Translational Medicine , 10 (454) , Article eaan1230. 10.1126/scitranslmed.aan1230. Green open access
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Birkbak, NJ; Li, Y; Pathania, S; Greene-Colozzi, A; Dreze, M; Bowman-Colin, C; Sztupinszki, Z; ... Richardson, AL; + view all (2018) Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple negative breast and serous ovarian cancers. Annals of Oncology , 29 (4) pp. 903-909. 10.1093/annonc/mdy049. Green open access
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Birley, K; Chester, K; Anderson, J; (2018) Antibody based therapy for childhood solid cancers. Current Opinion in Chemical Engineering , 19 pp. 153-162. 10.1016/j.coche.2018.01.005. Green open access
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Biswas, S; Alrubaiy, L; China, L; British Society of Gastroenterology Trainees’ Section; Lockett, M; Ellis, A; Hawkes, N; (2018) Trends in UK endoscopy training in the BSG trainees' national survey and strategic planning for the future. Frontline Gastroenterology , 9 (3) pp. 200-207. 10.1136/flgastro-2017-100848. Green open access
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Biswas, S; Quante, M; Leedham, S; Jansen, M; (2018) The metaplastic mosaic of Barrett's oesophagus. Virchows Archiv , 472 (1) pp. 43-54. 10.1007/s00428-018-2317-1. Green open access
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Bjerring, PN; Morgan, MY; Vilstrup, H; Nielsen, SM; Christensen, R; Gluud, LL; (2018) Medical interventions for prevention and treatment of hepatic encephalopathy in adults with cirrhosis: A network meta-analysis. Cochrane Database of Systematic Reviews (12) , Article CD013241. 10.1002/14651858.CD013241. Green open access
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Blackwood, DH; Vindrola-Padros, C; Mythen, MG; Walker, D; (2018) Advance-care-planning and end-of-life discussions in the perioperative period: a review of healthcare professionals' knowledge, attitudes, and training. British Journal of Anaesthesia 10.1016/j.bja.2018.05.075. (In press). Green open access
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Bláha, BAF; Morris, SA; Ogonah, OW; Crescente, V; Rosenberg, W; Maucourant, S; Mukhopadhyay, TK; (2018) Development of a high-throughput microscale cell disruption platform for Pichia pastoris in rapid bioprocess design. Biotechnology Progress , 34 (1) pp. 130-140. 10.1002/btpr.2555. Green open access
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Blas, P; Tolner, B; Ward, J; Chester, K; Hoare, M; (2018) The use of a surface active agent in the protection of a fusion protein during bioprocessing. Biotechnology and Bioengineering , 115 (11) pp. 2760-2770. 10.1002/bit.26817. Green open access
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Blencowe, N; Glasbey, J; Heywood, N; Kasivisvanathan, V; Lee, M; Nepogodiev, D; Wilkin, R; ... Williams, A; + view all (2018) Recognising contributions to work in research collaboratives: Guidelines for standardising reporting of authorship in collaborative research. International Journal of Surgery , 52 pp. 355-360. 10.1016/j.ijsu.2017.12.019. Green open access
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Bockenhauer, D; Kleta, R; (2018) Salt-Losing Tubulopathies in Children: What’s New, What’s Controversial? Journal of the American Society of Nephrology , 29 (3) pp. 727-739. 10.1681/ASN.2017060600. Green open access
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Bofinger, R; Zaw-Thin, M; Mitchell, NJ; Patrick, PS; Stowe, C; Gomez-Ramirez, A; Hailes, HC; ... Tabor, AB; + view all (2018) Development of Lipopolyplexes for Gene Delivery: a Comparison of the Effects of Differing Modes of Targeting Peptide Display on the Structure and Transfection Activities of Lipopolyplexes. Journal of Peptide Science , 24 (12) , Article e3131. 10.1002/psc.3131. Green open access
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Böiers, C; Richardson, SE; Laycock, E; Zriwil, A; Turati, VA; Brown, J; Wray, JP; ... Enver, T; + view all (2018) A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1. Developmental Cell , 44 (3) pp. 362-377. 10.1016/j.devcel.2017.12.005. Green open access
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Bonati, LH; Gregson, J; Dobson, J; McCabe, DJH; Nederkoorn, PJ; van der Worp, HB; de Borst, GJ; ... International Carotid Stenting Study investigators, .; + view all (2018) Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial. The Lancet Neurology , 17 (7) pp. 587-596. 10.1016/S1474-4422(18)30195-9. Green open access
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Bonfanti, M; Balabani, S; Alimohammadi, M; Agu, O; Homer-Vanniasinkam, S; Diaz, V; (2018) A simplified method to account for wall motion in patient-specific blood flow simulations of aortic dissection: Comparison with fluid-structure interaction. Medical Engineering and Physics , 58 pp. 72-29. 10.1016/j.medengphy.2018.04.014. Green open access
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Boniface, DR; Kaiser, F; Donos, N; Henderson, B; Alagarswarmy, R; Pelekos, G; Nibali, L; (2018) Association between circulating levels of heat-shock protein 27 and aggressive periodontitis. Cell Stress and Chaperones , 23 (5) pp. 847-856. 10.1007/s12192-018-0891-4. Green open access
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Bonmati, E; Hu, Y; Gibson, E; Uribarri, L; Keane, G; Gurusami, K; Davidson, B; ... Barratt, DC; + view all (2018) Determination of optimal ultrasound planes for the initialisation of image registration during endoscopic ultrasound-guided procedures. International Journal of Computer Assisted Radiology and Surgery , 13 (6) pp. 875-883. 10.1007/s11548-018-1762-2. Green open access
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Bor, J; Chiu, C; Ahmed, S; Katz, I; Fox, MP; Rosen, S; Yapa, M; ... Bärnighausen, T; + view all (2018) Failure to initiate HIV treatment in patients with high CD4 counts: evidence from demographic surveillance in rural South Africa. Tropical Medicine and International Health , 23 (2) 10.1111/tmi.13013. Green open access
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Borthwick, NJ; Lane, T; Moyo, N; Crook, A; Shim, JM; Baines, I; Wee, EG; ... Pepys, MB; + view all (2018) Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1. PLOS ONE , 13 (5) , Article e0197299. 10.1371/journal.pone.0197299. Green open access
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Böttcher, K; rombouts, K; Saffioti, F; Roccarina, D; Rosselli, M; Hall, A; Luong, T; ... Pinzani, M; + view all (2018) MAIT cells are chronically activated in patients with autoimmune liver disease and promote pro-fibrogenic hepatic stellate cell activation. Hepatology , 68 (1) pp. 172-186. 10.1002/hep.29782. Green open access
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Bouchery, Tiffany; Filbey, Kara; Shepherd, Amy; Chandler, Jodie; Patel, Deepa; Schmidt, Alfonso; Camberis, Mali; ... LeGros, Graham; + view all (2018) A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathogens , 14 (3) , Article e1006931. 10.1371/journal.ppat.1006931. Green open access
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Bouilly, J; Messina, A; Papadakis, G; Cassatella, D; Xu, C; Acierno, JS; Tata, B; ... Pitteloud, N; + view all (2018) DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development. Human Molecular Genetics , 27 (2) pp. 359-372. 10.1093/hmg/ddx408. Green open access
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Bourke, L; Stevenson, R; Turner, R; Hooper, R; Sasieni, P; Greasley, R; Morrissey, D; ... Rosario, DJ; + view all (2018) Exercise training as a novel primary treatment for localised prostate cancer: a multi-site randomised controlled phase II study. Scientific Reports , 8 , Article 8374. 10.1038/s41598-018-26682-0. Green open access
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Boyd, AS; Rodrigues, NP; (2018) Stem Cells Cycle toward Immune Surveillance. Immunity , 48 (2) pp. 187-190. 10.1016/j.immuni.2018.02.006. Green open access
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Boyle, EM; Ashby, C; Wardell, CP; Rowczenio, D; Sachchithanantham, S; Wang, Y; Johnson, SK; ... Wechalekar, AD; + view all (2018) The genomic landscape of plasma cells in systemic light chain amyloidosis. Blood , 132 (26) pp. 2775-2777. 10.1182/blood-2018-08-872226. Green open access
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Brackenridge, L; Finer, N; Batterham, RL; Pedram, K; Ding, T; Stephenson, J; Barry, J; (2018) Pre‐pregnancy weight loss in women with obesity requesting removal of their intra‐uterine contraceptive device in order to conceive: a pilot study of full meal replacement. Clinical Obesity , 8 (4) pp. 244-249. 10.1111/cob.12252. Green open access
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Brancolini, G; Maschio, MC; Cantarutti, C; Corazza, A; Fogolari, F; Bellotti, V; Corni, S; (2018) Citrate stabilized gold nanoparticles interfere with amyloid fibril formation: D76N and Delta N6 beta 2-microglobulin variants. Nanoscale , 10 (10) pp. 4793-4806. 10.1039/c7nr06808e. Green open access
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Brandner, SGP; Jaunmuktane, Z; Capper, D; Jones, DTW; Sill, M; Hovestadt, V; Schrimpf, D; ... Pfister, SM; + view all (2018) DNA methylation-based classification of central nervous system tumours. Nature. International Journal of Science , 555 pp. 469-474. 10.1038/nature26000. Green open access
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Braun, DA; Lovric, S; Schapiro, D; Schneider, R; Marquez, J; Asif, M; Hussain, MS; ... Hildebrandt, F; + view all (2018) Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. Journal of Clinical Investigation 10.1172/JCI98688. Green open access
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Bray, C; Wright, D; Haupt, S; Thomas, S; Stauss, H; Zamoyska, R; (2018) Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2. Frontiers in Immunology , 9 , Article 2595. 10.3389/fimmu.2018.02595. Green open access
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Bray, TJP; Bainbridge, A; Punwani, S; Ioannou, Y; Hall-Craggs, MA; (2018) Simultaneous Quantification of Bone Edema/Adiposity and Structure in Inflamed Bone Using Chemical Shift-Encoded MRI in Spondyloarthritis. Magnetic Resonance in Medicine , 79 (2) pp. 1031-1042. 10.1002/mrm.26729. Green open access
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Bridarolli, A; Odlyha, M; Nechyporchuk, O; Holmberg, K; Ruiz-Recasens, C; Bordes, R; Bozec, L; (2018) Evaluation of the Adhesion and Performance of Natural Consolidants for Cotton Canvas Conservation. ACS Applied Materials & Interfaces , 10 (39) pp. 33652-33661. 10.1021/acsami.8b10727. Green open access
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Bridge, JC; Amer, M; Morris, GE; Martin, NRW; Player, DJ; Knox, AJ; Aylott, JW; ... Rose, FRAJ; + view all (2018) Electrospun gelatin-based scaffolds as a novel 3D platform to study the function of contractile smooth muscle cells in vitro. Biomedical Physics & Engineering Express , 4 (4) , Article 045039. 10.1088/2057-1976/aace8f. Green open access
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Briggs, LC; Chan, AWE; Davis, CA; Whitelock, N; Hotiana, HA; Baratchian, M; Bagnéris, C; ... Barrett, TE; + view all (2018) IKKγ mimetic peptides block the resistance to apoptosis associated with KSHV infection. Journal of Virology , 92 (3) 10.1128/JVI.01170-17. Green open access
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Brilha, S; Chong, DLW; Khawaja, AA; Ong, CWM; Guppy, NJ; Porter, JC; Friedland, JS; (2018) Integrin alpha 2 beta 1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis. Frontiers in Immunology , 9 , Article 1348. 10.3389/fimmu.2018.01348. Green open access
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Brito-Zerón, P; Acar-Denizli, N; Ng, W-F; Zeher, M; Rasmussen, A; Mandl, T; Seror, R; ... Sjögren Big Data Consortium; + view all (2018) How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project). Clinical and Experimental Rheumatology , S36 (112(3)) pp. 102-112. Green open access
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Brittain, J; Dunford, C; Miah, S; Takhar, M; Morley, R; Rashid, T; (2018) Enormous mucocele following colonic graft neovagina formation in a transwoman. Urology Case Reports , 21 pp. 73-74. 10.1016/j.eucr.2018.08.014. Green open access
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Brizmohun Appayya, M; Adshead, J; Ahmed, HU; Allen, C; Bainbridge, A; Barrett, T; Giganti, F; ... Punwani, S; + view all (2018) National implementation of multi‐parametric magnetic resonance imaging for prostate cancer detection – recommendations from a UK consensus meeting. BJU International , 122 (1) pp. 13-25. 10.1111/bju.14361. Green open access
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Brizmohun Appayya, M; Sidhu, HS; Dikaios, N; Johnston, EW; Simmons, LA; Freeman, A; Kirkham, AP; ... Punwani, S; + view all (2018) Characterizing indeterminate (Likert-score 3/5) peripheral zone prostate lesions with PSA density, PI-RADS scoring and qualitative descriptors on multiparametric MRI. British Journal of Radiology , 91 (1083) , Article 20170645. 10.1259/bjr.20170645. Green open access
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Broderick, C; Hopkins, S; Mack, DJF; Aston, W; Pollock, R; Skinner, JA; Warren, S; (2018) Delays in the diagnosis and treatment of bone and joint tuberculosis in the United Kingdom. The Bone & Joint Journal , 100-B (1) pp. 119-124. 10.1302/0301-620X.100B1.BJJ-2017-0357.R1. Green open access
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Brown, JR; Bharucha, T; Breuer, J; (2018) Encephalitis diagnosis using metagenomics: application of next generation sequencing for undiagnosed cases. Journal of Infection , 76 (3) pp. 225-240. 10.1016/j.jinf.2017.12.014. Green open access
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Brown, LC; Ahmed, HU; Faria, R; El-Shater Bosaily, A; Gabe, R; Kaplan, RS; Parmar, M; ... Emberton, M; + view all (2018) Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study. Health Technology Assessment , 22 (39) xxxiii, 1-175. 10.3310/hta22390. Green open access
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Brown, NF; Carter, TJ; Ottaviani, D; Mulholland, P; (2018) Harnessing the immune system in glioblastoma. British Journal of Cancer , 119 (10) pp. 1171-1181. 10.1038/s41416-018-0258-8. Green open access
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Brown, NF; Williams, M; Arkenau, H-T; Fleming, RA; Tolson, J; Yan, L; Zhang, J; ... Mulholland, P; + view all (2018) A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [¹¹C]GSK2256098. Neuro-Oncology , 20 (12) pp. 1634-1642. 10.1093/neuonc/noy078. Green open access
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Brück, K; Jager, KJ; Zoccali, C; Bello, AK; Minutolo, R; Ioannou, K; Verbeke, F; ... Stel, V; + view all (2018) Progression and mortality in patients with CKD attending outpatient nephrology clinics across Europe: A novel analytic approach. Kidney International , 98 (6) pp. 1432-1441. (In press). Green open access
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Bruining, DH; Zimmermann, EM; Loftus, EV; Sandborn, WJ; Sauer, CG; Strong, SA; (2018) Consensus Recommendations for Evaluation, Interpretation, and Utilization of Computed Tomography and Magnetic Resonance Enterography in Patients With Small Bowel Crohn's Disease. Gastroenterology , 154 (4) pp. 1172-1194. 10.1053/j.gastro.2017.11.274. Green open access
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Bruinsma, SM; Zhang, L; Roobol, MJ; Bangma, CH; Steyerberg, EW; Nieboer, D; Van Hemelrijck, M; ... Buzza, M; + view all (2018) The Movember Foundation's GAP3 cohort: a profile of the largest global prostate cancer active surveillance database to date. BJU International , 121 (5) pp. 737-744. 10.1111/bju.14106. Green open access
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Bryce, G; MacBeth, N; Gulabivala, K; Ng, YL; (2018) The efficacy of supplementary sonic irrigation using the EndoActivator® system determined by removal of a collagen film from an ex vivo model. International Endodontic Journal , 51 (4) pp. 489-497. 10.1111/iej.12870. Green open access
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Buchan, T; Walkden, M; Jenkins, K; Sultan, P; Bandula, S; (2018) High-Frequency Jet Ventilation During Cryoablation of Small Renal Tumours. CardioVascular and Interventional Radiology , 41 (7) pp. 1067-1073. 10.1007/s00270-018-1921-4. Green open access
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Buchholz, BM; Lykoudis, PM; Ravikumar, R; Pollok, JM; Fusai, GK; (2018) Role of colectomy in preventing recurrent primary sclerosing cholangitis in liver transplant recipients. [Review]. World Journal of Gastroenterology , 24 (28) pp. 3171-3180. 10.3748/wjg.v24.i28.3171. Green open access
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Buckley, CD; Gordon, C; Isenberg, D; Snaith, M; Scott, DGI; Luqmani, R; Moots, R; ... Raza, K; + view all (2018) Obituary for Paul Bacon. Rheumatology , 57 (5) pp. 943-945. 10.1093/rheumatology/key030. Green open access
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Burn, E; Liddle, AD; Hamilton, TW; Judge, A; Pandit, HG; Murray, DW; Pinedo-Villanueva, R; (2018) Cost-effectiveness of unicompartmental compared with total knee replacement: a population-based study using data from the National Joint Registry for England and Wales. BMJ Open , 8 (4) , Article e020977. 10.1136/bmjopen-2017-020977. Green open access
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Burnett, AK; Das Gupta, E; Knapper, S; Khwaja, A; Sweeney, M; Kjeldsen, L; Hawkins, T; ... Russell, NH; + view all (2018) The Addition Of The MTORr Inhibitor, Everolimus, To Consolidation Therapy In Acute Myeloid Leukaemia: Experience From The UK NCRI AML17 Trial. Haematologica 10.3324/haematol.2018.189514. (In press). Green open access
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Burton, AR; Pallett, LJ; McCoy, LE; Suveizdyte, K; Amin, OE; Swadling, L; Alberts, E; ... Maini, MK; + view all (2018) Circulating and intrahepatic antiviral B cells are defective in hepatitis B. Journal of Clinical Investigation , 2018 pp. 1-16. 10.1172/JCI121960. Green open access
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Bystrom, J; Clanchy, FI; Taher, TE; Al-Bogami, M; Ong, VH; Abraham, DJ; Williams, RO; (2018) Functional and phenotypic heterogeneity of Th17 cells in health and disease. European Journal of Clinical Investigation , Article e13032. 10.1111/eci.13032. (In press). Green open access
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Caetano, J; Nihtyanova, SI; Harvey, J; Denton, CP; Ong, VH; (2018) Distinctive clinical phenotype of anti-centromere antibody-positive diffuse systemic sclerosis. Rheumatology Advances in Practice , 2 (1) , Article rky002. 10.1093/rap/rky002. Green open access
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Caimari, F; Keddie, S; Lunn, MP; D'Sa, S; Baldeweg, SE; (2018) Prevalence and course of endocrinopathy in POEMS syndrome. The Journal of Clinical Endocrinology & Metabolism 10.1210/jc.2018-01516. (In press). Green open access
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Calciolari, E; Ravanetti, F; Strange, A; Mardas, N; Bozec, L; Cacchioli, A; Kostomitsopoulos, N; (2018) Degradation pattern of a porcine collagen membrane in an in vivo model of guided bone regeneration. Journal of Periodontal Research , 53 (3) pp. 430-439. 10.1111/jre.12530. Green open access
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Calice-Silva, V; Sacomboio, E; Raimann, JG; Evans, R; Dos Santos Sebastião, C; Tchivango, AT; Kotanko, P; ... Pecoits-Filho, R; + view all (2018) Diagnostic performance of salivary urea nitrogen dipstick to detect and monitor acute kidney disease in patients with malaria. Malaria Journal , 17 (1) , Article 477. 10.1186/s12936-018-2627-4. Green open access
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Callender, LA; Carroll, EC; Beal, RWJ; Chambers, ES; Nourshargh, S; Akbar, AN; Henson, S; (2018) Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK. Aging Cell , 17 (1) , Article e12675. 10.1111/acel.12675. Green open access
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Calmont, A; Anderson, N; Suntharalingham, JP; Ang, R; Tinker, A; Scambler, PJ; (2018) Defective Vagal Innervation in Murine Tbx1 Mutant Hearts. Journal of Cardiovascular Development and Disease , 5 (4) , Article 49. 10.3390/jcdd5040049. Green open access
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Camon, S; Quiros, C; Saubi, N; Moreno, A; Marcos, MA; Eto, Y; Rofael, S; ... Perello, R; + view all (2018) Full blood count values as a predictor of poor outcome of pneumonia among HIV-infected patients. BMC Infectious Diseases , 18 , Article 189. 10.1186/s12879-018-3090-0. Green open access
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Campbell, M; Clarke, A; Symes, A; Workman, S; Stauss, H; Webster, AD; (2018) Investigating the Effectiveness, Acceptability and Impact on Healthcare Usage of Providing a Cognitive-Behavioural Based Psychological Therapy Service for Patients with Primary Antibody Deficiency. Journal of Clinical Immunology , 38 pp. 214-220. 10.1007/s10875-018-0481-3. Green open access
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Campochiaro, C; Host, LV; Ong, VH; Denton, CP; (2018) Development of systemic sclerosis in transgender females: a case series and review of the literature. Clinical and Experimental Rheumatology (In press).

Canfarotta, F; Lezina, L; Guerreiro, A; Czulak, J; Petukhov, A; Daks, A; Smolinska-Kempisty, K; ... Barlev, NA; + view all (2018) Specific Drug Delivery to Cancer Cells with Double-Imprinted Nanoparticles against Epidermal Growth Factor Receptor. Nano Letters , 18 (8) pp. 4641-4646. 10.1021/acs.nanolett.7b03206. Green open access
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Cantarutti, C; Bertoncin, P; Posocco, P; Hunashal, Y; Giorgetti, S; Bellotti, V; Fogolari, F; (2018) The interaction of β2-microglobulin with gold nanoparticles: impact of coating, charge and size. Journal of Materials Chemistry B , 6 (37) pp. 5964-5974. 10.1039/c8tb01129j. Green open access
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Cantarutti, C; Raj, G; Fogolari, F; Giorgetti, S; Corazza, A; Bellotti, V; Naumov, P; (2018) Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association. Chemical Communication , 54 (43) pp. 5422-5425. 10.1039/c8cc01053f. Green open access
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Cappellini, MD; Porter, JB; Viprakasit, V; Taher, AT; (2018) A paradigm shift on beta-thalassaemia treatment: How will we manage this old disease with new therapies? Blood Reviews , 32 (4) pp. 300-311. 10.1016/j.blre.2018.02.001. Green open access
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Capper, D; Engel, NW; Stichel, D; Lechner, M; Gloess, S; Schmid, S; Koelsche, C; ... Schueller, U; + view all (2018) DNA methylation-based reclassification of olfactory neuroblastoma. Acta Neuropathologica , 136 (2) pp. 255-271. 10.1007/s00401-018-1854-7. Green open access
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Cardoso, MJ; Vrieling, C; Cardoso, JS; Oliveira, HP; Williams, NR; Dixon, JM; PICTURE Project Clinical Trial Team; (2018) The value of 3D images in the aesthetic evaluation of breast cancer conservative treatment. Results from a prospective multicentric clinical trial. The Breast , 41 pp. 19-24. 10.1016/j.breast.2018.06.008. Green open access
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Carey, B; Mercadante, V; Fedele, S; Glover, M; Cale, C; Porter, S; (2018) STAT3-Deficient hyperimmunoglobulin E syndrome: report of a case with orofacial granulomatosis–like disease. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology , 126 (5) e252-e257. 10.1016/j.oooo.2018.07.006. Green open access
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Carloni, V; Lulli, M; Madiai, S; Mello, T; Hall, A; Luong, TV; Pinzani, M; ... Galli, A; + view all (2018) CHK2 overexpression and mislocalisation within mitotic structures enhances chromosomal instability and hepatocellular carcinoma progression. Gut , 67 (2) pp. 348-361. 10.1136/gutjnl-2016-313114. Green open access
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Carrier, ME; Kwakkenbos, L; Boutron, I; Welling, J; Sauve, M; van den Ende, C; Schouffoer, AA; ... Manning, J; + view all (2018) Randomized feasibility trial of the Scleroderma patient-centered intervention network hand exercise program (SPIN-HAND): Study protocol. Journal of Scleroderma and Related Disorders , 3 (1) pp. 91-97. 10.5301/jsrd.5000263. Green open access
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Carty, F; Corbett, JM; Cunha, JPMCM; Reading, JL; Tree, TIM; Ting, AE; Stubblefield, SR; (2018) Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner. Frontiers In Immunology , 9 , Article 645. 10.3389/fimmu.2018.00645. Green open access
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Casali, PG; Bielack, S; Abecassis, N; Aro, HT; Bauer, S; Biagini, R; Bonvalot, S; ... Blay, JY; + view all (2018) Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology , 29 (4) pp. 79-95. 10.1093/annonc/mdy310. Green open access
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Cassatella, D; Howard, SR; Acierno, JS; Xu, C; Papadakis, GE; Santoni, FA; Dwyer, AA; ... Pitteloud, N; + view all (2018) Congenital hypogonadotropic hypogonadism and constitutional delay of growth and puberty have distinct genetic architectures. European Journal of Endocrinology , 178 (4) pp. 377-388. 10.1530/EJE-17-0568. Green open access
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Catling, F; Spithourakis, GP; Riedel, S; (2018) Towards automated clinical coding. International Journal of Medical Informatics , 120 pp. 50-61. 10.1016/j.ijmedinf.2018.09.021. Green open access
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Catto, JWF; Khetrapal, P; Ambler, G; Sarpong, R; Khan, MS; Tan, M; Feber, A; ... Kelly, JD; + view all (2018) Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study. BMJ Open , 8 (8) , Article e020500. 10.1136/bmjopen-2017-020500. Green open access
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Catto, JWF; Khetrapal, P; Ambler, G; Sarpong, R; Potyka, I; Khan, S; Tan, M; ... Kelly, JD; + view all (2018) Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients. European Urology , 74 (4) pp. 531-534. 10.1016/j.eururo.2018.05.008. Green open access
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Cereser, B; Jansen, M; Austin, E; Elia, G; Mcfarlane, T; van Deurzen, CH; Sieuwerts, AM; ... Mcdonald, SA; + view all (2018) Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells. Journal of Pathology , 244 (1) pp. 61-70. 10.1002/path.4989. Green open access
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Cerquiglini, A; Henckel, J; Hothi, H; Rotigliano, N; Hirschmann, MT; Hart, AJ; (2018) 3D patient imaging and retrieval analysis help understand the clinical importance of rotation in knee replacements. Knee Surgery, Sports Traumatology, Arthroscopy , 26 (11) pp. 3351-3361. 10.1007/s00167-018-4891-9. Green open access
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Cerquiglini, A; Henckel, J; Hothi, HS; Dall'Ava, L; Shearing, P; Hirschmann, MT; Hart, AJ; (2018) Computed Tomography Techniques Help Understand Wear Patterns in Retrieved Total Knee Arthroplasty. The Journal of Arthroplasty , 33 (9) pp. 3030-3037. 10.1016/j.arth.2018.04.010. Green open access
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Cerquiglini, A; Henckel, J; Hothi, HS; Di Laura, A; Skinner, JA; Hart, AJ; (2018) Inflammatory cell-induced corrosion in total knee arthroplasty: a retrieval study. Journal of Biomedical Materials Research Part B: Applied Biomaterials , 106 (1) pp. 460-467. 10.1002/jbm.b.33820. Green open access
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Chaigne, B; Clary, G; Le Gall, M; Dumoitier, N; Fernandez, C; Lofek, S; Chafey, P; ... Mouthon, L; + view all (2018) Proteomic Analysis of Human Scleroderma Fibroblasts Response to Transforming Growth Factor-ß. Proteomics Clinical Applications , Article e1800069. 10.1002/prca.201800069. Green open access
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Chain, G; Marshall, E; Geddie, C; Joseph, S; Chain, B; Clark, C; (2018) Learning from Excellence: the 'Yaytix' programme. Scottish Medical Journal , 63 (4) pp. 104-107. 10.1177/0036933018799605. Green open access
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Chakravarthy, A; Furness, A; Joshi, K; Ghorani, E; Ford, K; Ward, MJ; King, EV; ... Fenton, TR; + view all (2018) Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation. [Corrigendum]. Nature Communications , 9 , Article 4642. 10.1038/s41467-018-07155-4. Green open access
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Chand, M; Keller, DS; Devoto, L; McGurk, M; (2018) Furthering Precision in Sentinel Node Navigational Surgery for Oral Cancer: a Novel Triple Targeting System. Journal of Fluorescence , 28 (2) pp. 483-486. 10.1007/s10895-018-2211-x. Green open access
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