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Immunoglobulin G4-related sclerosing cholangitis

Goodchild, G; Pereira, SP; Webster, G; (2018) Immunoglobulin G4-related sclerosing cholangitis. Korean Journal of Internal Medicine , 33 (5) pp. 841-850. 10.3904/kjim.2018.018. (In press). Green open access

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Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG4-SC, namely, primary sclerosing cholangitis and cholangiocarcinoma, outline diagnostic criteria for IgG4-SC, provide insight into possible pathophysiological mechanisms underlying the disease and discuss short and long-term management options of this recently described disease.

Type: Article
Title: Immunoglobulin G4-related sclerosing cholangitis
Location: Korea (South)
Open access status: An open access version is available from UCL Discovery
DOI: 10.3904/kjim.2018.018
Publisher version: https://doi.org/10.3904/kjim.2018.018
Language: English
Additional information: This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Autoimmune pancreatitis, Biliary stricture, Cholangitis, sclerosing, Immunoglobulin G4 cholangiopathy, Immunoglobulin G4 related disease
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
URI: https://discovery.ucl.ac.uk/id/eprint/10053686
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