Hurst, JR;
(2018)
Consolidation and Exacerbation of COPD.
Medical Sciences
, 6
(2)
, Article 44. 10.3390/medsci6020044.
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Abstract
20% of chronic obstructive pulmonary disease (COPD) patients admitted to hospital because of an 'exacerbation' will have consolidation visible on a chest X-ray. The presence of consolidation is associated with higher mortality. Imperfect definitions of COPD exacerbation and pneumonia, and incomplete and imperfect diagnostic tests, have resulted in a debate about whether these episodes are best thought of as 'exacerbation with consolidation' or 'pneumonia in a person with COPD'. With the current views that exacerbations are not all identical, and that they can be 'phenotyped' to identify episodes with different prognosis and treatment response, perhaps these episodes are best-considered a phenotype of exacerbation. Whatever the terminology, the important clinical message is to recognise that those with consolidation have higher mortality, and likely different responses to treatment.
| Type: | Article |
|---|---|
| Title: | Consolidation and Exacerbation of COPD |
| Location: | Switzerland |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3390/medsci6020044 |
| Publisher version: | http://doi.org/10.3390/medsci6020044 |
| Language: | English |
| Additional information: | Copyright © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | COPD, Exacerbation, Pneumonia, Bacteria, Consolidation |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10050774 |
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