UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Histological Validation of in-vivo VERDICT MRI for Prostate using 3D Personalised Moulds

Bonet-Carne, E; Tariq, M; Pye, H; Appayya, MB; Haider, A; Bayley, C; Jacobs, J; ... Panagiotaki, E; + view all (2018) Histological Validation of in-vivo VERDICT MRI for Prostate using 3D Personalised Moulds. In: Proceedings of the Joint Annual Meeting ISMRM-ESMRMB 2018. International Society for Magnetic Resonance in Medicine (ISMRM) (In press). Green open access

[img]
Preview
Text
bonet-carne_ISMRM2018VERDICT_Submitted_version.pdf - Accepted version

Download (709kB) | Preview

Abstract

VERDICT analysis can successfully distinguish benign from malignant prostate tissue in-vivo showing promising results as a cancer diagnostic tool. However, the accuracy with which model parameters reflect the underlying tissue characteristics is unknown. In this study, we quantitatively compare the intracellular, extracellular-extravascular and vascular volume fractions derived from in-vivo VERDICT MRI against histological measurements from prostatectomies. We use 3D-printed personalised moulds designed from in-vivo MRI that help preserve the orientation and location of the gland and aid histological alignment. Results from the first samples using the 3D mould pipeline show good agreement between in-vivo VERDICT estimates and histology.

Type: Proceedings paper
Title: Histological Validation of in-vivo VERDICT MRI for Prostate using 3D Personalised Moulds
Event: Joint Annual Meeting ISMRM-ESMRMB, 16- 21 June 2018, Paris Expo Porte de Versailles, Paris, France
Location: Paris
Dates: 16 June 2018 - 21 June 2018
Open access status: An open access version is available from UCL Discovery
Publisher version: http://archive.ismrm.org/2018/0133.html
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10042820
Downloads since deposit
51Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item