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Cancer drug tackles overgrowth syndrome

Semple, RK; Vanhaesebroeck, B; (2018) Cancer drug tackles overgrowth syndrome. Nature , 558 (7711) pp. 522-525. Green open access

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Abstract

Abnormal activity of the enzyme PI3K can drive cancer growth, and mutations in a PI3K subunit can sometimes lead to non-cancerous overgrowth. A cancer drug that inhibits PI3K dramatically reduces such overgrowth.

Type: Article
Title: Cancer drug tackles overgrowth syndrome
Open access status: An open access version is available from UCL Discovery
Publisher version: https://rdcu.be/1SXW
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: https://discovery.ucl.ac.uk/id/eprint/10057246
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