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A Scalable Optoelectronic Neural Probe Architecture With Self-Diagnostic Capability

Zhao, H; Soltan, A; Maaskant, P; Dong, N; Sun, X; Degenaar, P; (2018) A Scalable Optoelectronic Neural Probe Architecture With Self-Diagnostic Capability. IEEE Transactions on Circuits and Systems I: Regular Papers , 65 (8) pp. 2431-2442. 10.1109/TCSI.2018.2792219. Green open access

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Abstract

There is a growing demand for the development of new types of implantable optoelectronics to support both basic neuroscience and optogenetic treatments for neurological disorders. Target specification requirements include multisite optical stimulation, programmable radiance profile, safe operation, and miniaturization. It is also preferable to have a simple serial interface rather than large numbers of control lines. This paper demonstrates an optrode structure comprising of a standard complementary metal-oxide-semiconductor process with 18 optical stimulation drivers. Furthermore, diagnostic sensing circuitry is incorporated to determine the long-term functionality of the photonic elements. A digital control system is incorporated to allow independent multisite control and serial communication with external control units.

Type: Article
Title: A Scalable Optoelectronic Neural Probe Architecture With Self-Diagnostic Capability
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/TCSI.2018.2792219
Publisher version: http://doi.org/10.1109/TCSI.2018.2792219
Language: English
Additional information: Copyright © 2019 IEEE. This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0/
Keywords: Active optrode, neural stimulation, optogenetics, implantable, self-diagnostic.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
URI: https://discovery.ucl.ac.uk/id/eprint/10067906
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