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What a dog transmissible tumor can teach us about cancer regression

Fassati, A; (2018) What a dog transmissible tumor can teach us about cancer regression. [Editorial comment]. Molecular & Cellular Oncology , 5 (4) 10.1080/23723556.2018.1472059. Green open access

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Abstract

The canine transmissible venereal tumor (CTVT) is one of the few clonally transmissible cancers in nature and the only one that fully regresses following treatment with vincristine. The molecular signature of CTVT regression has been described in a recent paper published in Cancer Cell, revealing some fundamental insights into cancer regression.

Type: Article
Title: What a dog transmissible tumor can teach us about cancer regression
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/23723556.2018.1472059
Publisher version: https://doi.org/10.1080/23723556.2018.1472059
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: cancer, regression, dog, transmissible, chemotherapy, CCL5, inflammation, rejection, Biology of malignant cells
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/10053211
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