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Potential benefits of incorporating energy information when estimating attenuation from PET data

Brusaferri, L; Bousse, A; Efthimiou, N; Emond, E; Atkinson, D; Ourselin, S; Hutton, BF; ... Thielemans, K; + view all (2018) Potential benefits of incorporating energy information when estimating attenuation from PET data. In: 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). IEEE Xplore: New York, NY, USA. Green open access

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Abstract

This study explores the advantages of using a different energy window for each individual annihilation photon when estimating attenuation from scattered PET data. Several studies have shown that scattered data can be used to reconstruct the density distribution of the object, although they are limited to simple phantoms and ideal energy measurements. We have incorporated a realistic photon detection probability model into our algorithm, as well as the dependence of attenuation on photon energy. In the proposed method each detector can assign a photon to either energy window. Preliminary results on point source simulations have shown that using a different window for each annihilation photon allows to derive spatial information on both attenuation and activity distribution, and to isolate subsets of scatter angles depending on the energy window pair used. XCAT simulations demonstrated that it is possible to yield an attenuation map from scattered PET data only and that MR information can increase reconstruction accuracy. This method can also compensate for errors typically introduced from the MRAC, such as truncation artifacts.

Type: Proceedings paper
Title: Potential benefits of incorporating energy information when estimating attenuation from PET data
Event: IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 21-28 October 2017, Atlanta, GA, USA
ISBN-13: 9781538622827
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/NSSMIC.2017.8532765
Publisher version: https://doi.org/10.1109/NSSMIC.2017.8532765
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Attenuation, Image reconstruction, Photonics, Microsoft Windows, Energy measurement, Phantoms, Detectors
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Metabolism and Experi Therapeutics
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10066131
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