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Ethical considerations in global HIV phylogenetic research

Coltart, CEM; Hoppe, A; Parker, M; Dawson, L; Amon, JJ; Simwinga, M; Geller, G; ... Ethics in HIV Phylogenetics Working Group, ; + view all (2018) Ethical considerations in global HIV phylogenetic research. The Lancet HIV , 5 (11) e656-e666. 10.1016/S2352-3018(18)30134-6. Green open access

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Abstract

Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.

Type: Article
Title: Ethical considerations in global HIV phylogenetic research
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/S2352-3018(18)30134-6
Publisher version: http://dx.doi.org/10.1016/S2352-3018(18)30134-6
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
URI: https://discovery.ucl.ac.uk/id/eprint/10055681
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