Strauss, SJ;
Anninga, J;
Baglio, R;
Baumhoer, D;
Behjati, S;
Bielack, S;
Boye, K;
... Whelan, J; + view all
(2018)
Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma.
Clinical Sarcoma Research
, 8
, Article 17. 10.1186/s13569-018-0103-0.
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Abstract
This report summarizes the proceedings of the 4th European Bone Sarcoma Networking Meeting, held in London, England, on 21 June 2017. The meeting brought together scientific and clinical researchers and representatives from sarcoma charities from 19 countries representing five networks across Europe, to present and discuss new developments on bone sarcoma. In view of the challenges is poses, the meeting focussed primarily on osteosarcoma with presentations on developments in our understanding of osteosarcoma genetics and immunology as well as results from preclinical investigations and discussion of recent and ongoing clinical trials. These include studies examining the efficacy of multi-targeted tyrosine kinase inhibitors and checkpoint inhibitors, as well as those with molecular profiling to stratify patients for specific therapies. Discussion was centred on generation of new hypotheses for collaborative biological and clinical investigations, the ultimate goal being to improve therapy and outcome in patients with bone sarcomas.
| Type: | Article |
|---|---|
| Title: | Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/s13569-018-0103-0 |
| Publisher version: | https://doi.org/10.1186/s13569-018-0103-0 |
| Language: | English |
| Additional information: | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| Keywords: | Osteosarcoma, Bone sarcoma, Immunotherapy, Genomics, Translational research |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10089712 |
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