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Sepsis - thoughtful management for the non-expert

Tidswell, R; Singer, M; (2018) Sepsis - thoughtful management for the non-expert. Clinical Medicine , 18 (1) pp. 62-68. 10.7861/clinmedicine.18-1-62. Green open access

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Abstract

Sepsis is a common and often devastating medical emergency with a high mortality rate and, in many survivors, long-term morbidity. It is defi ned as the dysregulated host response to infection resulting in organ dysfunction, and its incidence is increasing as the population ages. However, it is a treatable and potentially reversible condition, especially if identifi ed and treated promptly. A sound understanding of sepsis is crucial for optimal care. Although general guidelines are available for management, here we provide a foundation of understanding to encourage thoughtful, personalised management of sepsis during the acute phase. We provide an overview of the epidemiology, the new Sepsis-3 defi nitions, pathophysiology, clinical presentations, and investigation and management of sepsis for the non-expert.

Type: Article
Title: Sepsis - thoughtful management for the non-expert
Open access status: An open access version is available from UCL Discovery
DOI: 10.7861/clinmedicine.18-1-62
Publisher version: http://doi.org/10.7861/clinmedicine.18-1-62
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: sepsis, infection, acute medicine, intensive care medicine, septic shock, medical education
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Internal Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10049736
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