UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Mismatch between suspected pyelonephritis and microbiological diagnosis: a cohort study from a UK teaching hospital

Shallcross, L; Gaskell, K; Fox-Lewis, A; Bergstrom, M; Noursadeghi, M; (2018) Mismatch between suspected pyelonephritis and microbiological diagnosis: a cohort study from a UK teaching hospital. Journal of Hospital Infection , 98 (2) pp. 219-222. 10.1016/j.jhin.2017.09.029. Green open access

[thumbnail of Shallcross_pyelo_220917_clean.pdf]
Preview
Text
Shallcross_pyelo_220917_clean.pdf - Accepted Version

Download (403kB) | Preview

Abstract

Urinary tract infections are a common reason for prescribing empirical antibiotics in the emergency department. This study investigated the role of microbiological culture and urinalysis in the diagnosis of pyelonephritis by extracting data on 105 patients with a clinical diagnosis of pyelonephritis at a London teaching hospital. In total, 99 of 102 patients were treated empirically with intravenous antibiotics, but only 55 of 100 patients who were sampled had microbiological evidence of infection in urine and/or blood. Almost half (10/21) of the patients with a negative urine dipstick test had a positive urine culture. Diagnostic uncertainty in this context undoubtedly drives inappropriate antibiotic use.

Type: Article
Title: Mismatch between suspected pyelonephritis and microbiological diagnosis: a cohort study from a UK teaching hospital
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.jhin.2017.09.029
Publisher version: http://doi.org/10.1016/j.jhin.2017.09.029
Language: English
Additional information: © 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Antibiotic stewardship, Antimicrobial resistance, Diagnostics, Urinary tract infection
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
URI: https://discovery.ucl.ac.uk/id/eprint/10029830
Downloads since deposit
108Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item