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A review of inflammatory idiopathic myopathy focusing on polymyositis

Clark, KEN; Isenberg, DA; (2018) A review of inflammatory idiopathic myopathy focusing on polymyositis. European Journal of Neurology , 25 (1) pp. 13-23. 10.1111/ene.13357. Green open access

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Abstract

Inflammatory idiopathic myopathies are a group of autoimmune diseases affecting predominantly the proximal skeletal muscles, with raised muscle enzymes, with or without skin involvement and extramuscular organ involvement. Autoantibodies help to characterize patients into different clinical phenotypes. Successful treatment necessitates controlling inflammation early with corticosteroids and invariably requires additional immunosuppressive therapy. This review focuses on the aetiology, pathogenesis, clinical presentation, investigations and management of patients presenting with inflammatory idiopathic myopathies, predominantly focusing on polymyositis and antisynthetase syndrome.

Type: Article
Title: A review of inflammatory idiopathic myopathy focusing on polymyositis
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/ene.13357
Publisher version: http://dx.doi.org/10.1111/ene.13357
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: anti-synthetase syndrome, inflammatory idiopathic myositis, polymyositis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10050621
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