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Tackling delirium: a crucial target for improving clinical outcomes

Asadi, H; Martin, D; McKenna, H; (2018) Tackling delirium: a crucial target for improving clinical outcomes. British Journal of Hospital Medicine , 79 (3) pp. 132-135. 10.12968/hmed.2018.79.3.132. Green open access

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Abstract

Delirium is a common and debilitating syndrome in hospitalized patients, and its impact on mortality, morbidity and duration of hospital admission is increasingly apparent. Delirium is a complex phenomenon, for which there is no specific treatment, but research over the last decade has revealed contributing factors, many of which are modifiable, and preventative strategies have demonstrated benefit. This review highlights the importance of reducing the impact of delirium on hospitalized patients, and summarizes the current evidence for strategies to achieve this. Current recommendations focus on the pre-emptive implementation of multi-modal non-pharmacological interventions to reduce the occurrence of delirium in the first place, and routine monitoring using validated tools to identify delirious patients early. Potential therapies for established delirium remain controversial.

Type: Article
Title: Tackling delirium: a crucial target for improving clinical outcomes
Open access status: An open access version is available from UCL Discovery
DOI: 10.12968/hmed.2018.79.3.132
Language: English
Additional information: © 2018 MA Healthcare Ltd. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Medicine, General & Internal, General & Internal Medicine, INTENSIVE-CARE-UNIT, MECHANICALLY VENTILATED PATIENTS, DECREASES DELIRIUM, RANDOMIZED-TRIAL, ELDERLY-PATIENTS, DEXMEDETOMIDINE, PREVENTION, MANAGEMENT, DIAGNOSIS, INTERVENTIONS
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10047319
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