Browse by UCL Department: listings for include files
- UCL (194525)
- UCL (194525)
- Provost and Vice Provost Offices (193300)
- School of Life and Medical Sciences (94917)
- Faculty of Population Health Sciences (32038)
- Inst of Clinical Trials and Methodology (3081)
- MRC Clinical Trials Unit at UCL (2416)
- Inst of Clinical Trials and Methodology (3081)
- Faculty of Population Health Sciences (32038)
- School of Life and Medical Sciences (94917)
- Provost and Vice Provost Offices (193300)
- UCL (194525)
2025
Abdalla, S;
Compagnucci, A;
Bamford, A;
Chan, MK;
Ramos, JT;
Riault, Y;
Saidi, Y;
... Welch, S; + view all
(2025)
Assessment of the steady-state drug-drug interactions between dolutegravir and ritonavir-boosted darunavir in adolescents.
AIDS
10.1097/QAD.0000000000004223.
(In press).
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Alexander, Suceena;
Raj Raj, Selvin Sundar;
Varughese, Santosh;
David, Vinoi George;
Jose, Nisha;
K, Reka;
Choodari-Oskooei, Babak;
... John, George T; + view all
(2025)
WCN25-3803 Design of Randomized Embedded Adaptive Platform Clinical Trial in South Asian Kidney Biopsy-Proven Primary Glomerular Diseases: Multi-Center, Multi-Arm and Multi-Stage.
Presented at: ISN World Congress of Nephrology (WCN) 2025, New Delhi, India.
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Appanna, Nathan;
Mew, Rosie;
Williams, Sophie;
Starkey, Thomas;
Patel, Grisma;
Hudson, Laura;
Burke, Emma;
... Lee, Lennard; + view all
(2025)
Safe prescribing in cancer patients during the COVID-19 pandemic and outcomes following restart of cancer care following SARS-CoV-2 infection: The COV-SPOT initiative.
International Journal of Cancer
, 156
(11)
pp. 2087-2093.
10.1002/ijc.35377.
|
Bedia, Jacob S;
Jacobs, Ian J;
Ryan, Andy;
Gentry-Maharaj, Aleksandra;
Burnell, Matthew;
Singh, Naveena;
Manchanda, Ranjit;
... Skates, Steven J; + view all
(2025)
Estimating the ovarian cancer CA-125 preclinical detectable phase, in-vivo tumour doubling time, and window for detection in early stage: an exploratory analysis of UKCTOCS.
eBioMedicine
, 112
, Article 105554. 10.1016/j.ebiom.2024.105554.
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Bhamani, A;
Katsampouris, E;
Bojang, F;
Verghese, P;
Creamer, A;
Prendecki, R;
Khaw, CR;
... Quaife, SL; + view all
(2025)
Uptake and 4-week outcomes of an ‘opt-out’ smoking cessation referral strategy in a London-based lung cancer screening setting.
BMJ Open Respiratory Research
, 12
(1)
, Article e002337. 10.1136/bmjresp-2024-002337.
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Bhamani, Amyn;
Creamer, Andrew;
Verghese, Priyam;
Prendecki, Ruth;
Horst, Carolyn;
Tisi, Sophie;
Hall, Helen;
... SUMMIT consortium, .; + view all
(2025)
Low-dose CT for lung cancer screening in a high-risk population (SUMMIT): a prospective, longitudinal cohort study.
The Lancet Oncology
10.1016/S1470-2045(25)00082-8.
(In press).
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Birrell, Paul J;
Blake, Joshua;
Kandiah, Joel;
Alexopoulos, Angelos;
van Leeuwen, Edwin;
Pouwels, Koen;
Ghosh, Sanmitra;
... De Angelis, Daniela; + view all
(2025)
Real-time modelling of the SARS-CoV-2 pandemic in England 2020-2023: a challenging data integration.
Journal of the Royal Statistical Society: Statistics in Society Series A
, Article qnaf030. 10.1093/jrsssa/qnaf030.
(In press).
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Bouche, Gauthier;
Gilbert, Duncan;
Quartagno, Matteo;
Dehbi, Hakim-Moulay;
Merrick, Sophie;
Barjesteh van Waalwijk van Doorn-Khosrovani, Sahar;
Stephens, Richard;
... Langley, Ruth E; + view all
(2025)
Determining the optimal use of approved drugs in oncology.
The Lancet Oncology
, 26
(5)
e282-e294.
10.1016/S1470-2045(25)00037-3.
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Bown, Abbie;
Peto, Tim;
Sweed, Angela;
Catton, Matthew;
Nelthorpe-Cowne, Joshua;
Benford, Tracy;
LFD laboratory team, .;
... Vipond, Richard; + view all
(2025)
Laboratory evaluation of 185 commercial assays for detecting SARS-CoV-2: the UK response for mass testing.
EClinicalMedicine
, Article 103416. 10.1016/j.eclinm.2025.103416.
(In press).
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Broer, S. D. Lana;
White, Ian R;
Morris, Tim P;
Weir, Isabelle R;
Fiocco, Marta;
Quartagno, Matteo;
(2025)
Summary measures in non-inferiority clinical trials with a time-to-event outcome: an empirical comparison of power.
Summary measures in non-inferiority clinical trials with a time-to-event outcome: an empirical comparison of power
, 25
, Article 139. 10.1186/s12874-025-02576-4.
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Butt, Zaran;
Sharif, Saad;
Ahmad, Mohammed;
Daly, Michael J;
O'Neill, James;
Gentry-Maharaj, Aleksandra;
Godolphin, Peter J;
(2025)
Mechanical circulatory support for infarct-related cardiogenic shock: a systematic review, pairwise and network meta-analysis.
European Heart Journal Open
, 5
(4)
, Article oeaf091. 10.1093/ehjopen/oeaf091.
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Chan, An-Wen;
Boutron, Isabelle;
Hopewell, Sally;
Moher, David;
Schulz, Kenneth F;
Collins, Gary S;
Tunn, Ruth;
... Hróbjartsson, Asbjørn; + view all
(2025)
SPIRIT 2025 statement: updated guideline for protocols of randomized trials.
Nature Medicine
10.1038/s41591-025-03668-w.
(In press).
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Chan, An-Wen;
Boutron, Isabelle;
Hopewell, Sally;
Moher, David;
Schulz, Kenneth F;
Collins, Gary S;
Tunn, Ruth;
... Hróbjartsson, Asbjørn; + view all
(2025)
SPIRIT 2025 Statement:
Updated Guideline for Protocols of Randomized Trials.
Journal of the American Medical Association (JAMA)
, Article Special Communication. 10.1001/jama.2025.4486.
(In press).
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Chan, An-Wen;
Boutron, Isabelle;
Hopewell, Sally;
Moher, David;
Schulz, Kenneth F;
Collins, Gary S;
Tunn, Ruth;
... Hróbjartsson, Asbjørn; + view all
(2025)
SPIRIT 2025 statement: updated guideline for protocols of randomised trials.
BMJ
, 389
, Article e081477. 10.1136/bmj-2024-081477.
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Chimukuche, Rujeko Samanthia;
Shandu, Londiwe;
Zulu, Silindile;
Khanyile, Phindile;
Singh, Nishanta;
Gaffoor, Zakir;
Kawuma, Rachel;
... Seeley, Janet; + view all
(2025)
HIV risk perception, trust and PrEP adherence among participants in an HIV prevention trial: a qualitative longitudinal study, South Africa.
BMJ Open
, 15
(4)
, Article e086742. 10.1136/bmjopen-2024-086742.
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Chintoloa, Elizabeth;
Connon, Roisin;
George, Elizabeth;
Chagaluka, George;
M'baya, Bridon;
Walker, Sarah;
Kennedy, Neil;
(2025)
Cardiac Output Measurement in Malawian children aged 2 months to 12 years hospitalised with severe anaemia (COM-TRACT).
International Health
(In press).
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Choodari-Oskooei, Babak;
Robertson, David S;
(2025)
Confidence Intervals for Adaptive Trial Designs I: A Methodological Review.
Statistics in Medicine
, 44
(18-19)
, Article e70174. 10.1002/sim.70174.
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Choodari-Oskooei, Babak;
Robertson, David S;
(2025)
Confidence Intervals for Adaptive Trial Designs II: Case Study and Practical Guidance.
Statistics in Medicine
, 44
(18-19)
, Article e70202. 10.1002/sim.70202.
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Collin, Lindsay J;
Cushing-Haugen, Kara L;
Terry, Kathryn L;
Goode, Ellen L;
Wu, Anna H;
Harris, Holly R;
Sasamoto, Naoko;
... Doherty, Jennifer A; + view all
(2025)
Patterns of Associations with Epidemiologic Factors by High-Grade Serous Ovarian Cancer Gene Expression Subtypes.
Cancer Epidemiology, Biomarkers & Prevention
, 34
(5)
pp. 762-773.
10.1158/1055-9965.EPI-24-1143.
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Cooke, Graham;
Le Manh, Hung;
Flower, Barnaby;
McCabe, Leanne;
Vu Thi Kim, Hang;
Vo Thi, Thu;
Dang Trong, Thuan;
... Walker, Ann Sarah; + view all
(2025)
Treatment Options to Support the Elimination of Hepatitis C: an open label, factorial randomised controlled trial.
The Lancet
, 405
pp. 1769-1780.
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Cragg, William J;
Clifton-Hadley, Laura;
Dearling, Jeremy;
Dutton, Susan J;
Gillies, Katie;
Hardy, Pollyanna;
Hind, Daniel;
... Verghis, Rejina; + view all
(2025)
Standardising management of consent withdrawal and other clinical trial participation changes: The UKCRC Registered Clinical Trials Unit Network’s PeRSEVERE project.
Clinical Trials
10.1177/17407745251344524.
(In press).
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Cregan, Jack;
Nsonwu, Olisaeloka;
Chudasama, Dimple;
Hopkins, Susan;
Muller-Pebody, Berit;
Hope, Russell;
Walker, Ann;
(2025)
Case ascertainment of a potential centrally-implemented, automated system for national surveillance of healthcare-associated infections in England 2016-2023.
Eurosurveillance
(In press).
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Cross, Elizabeth LA;
Llewelyn, Martin J;
Walker, Ann;
Hayward, Gail N;
(2025)
Comparing thermal imaging and non-contact infrared thermometers for monitoring skin temperature in a prospective cohort with lower limb cellulitis.
BMJ Open
(In press).
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Datta, Soumitra S;
Samanta, Bidisha;
Chatterjee, Sanjoy;
Mallick, Indranil;
Sharma, Atul;
Gangopadhyay, Gargi;
Chattopadhyay, Shreshta;
... Menon, Usha; + view all
(2025)
Conduct of cancer clinical trials: a qualitative study reporting views of patients, caregivers, public and clinical researchers.
ecancermedicalscience
, 19
, Article 1950. 10.3332/ecancer.2025.1950.
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Dunn, David T;
Mccabe, Leanne;
Ward, Denise;
Phillips, Andrew N;
Lampe, Fiona C;
Burns, Fiona;
Delpech, Valerie;
... Rodger, Alison J; + view all
(2025)
Assessing Whether Providing Regular, Free HIV Self-Testing Kits Reduces the Time to HIV Diagnosis: An Internet-Based, Randomized Controlled Trial in Men Who Have Sex With Men.
JAIDS Journal of Acquired Immune Deficiency Syndromes
, 98
(3)
pp. 274-281.
10.1097/QAI.0000000000003564.
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Duong, Trinh;
Brigden, Joanna;
Simon Schaaf, H;
Garden, Frances;
Marais, Ben J;
Anh Nguyen, Thu;
White, Ian R;
... Fox, Greg J; + view all
(2025)
A Meta-Analysis of Levofloxacin for Contacts of Multidrug-Resistant Tuberculosis.
NEJM Evidence
, 4
(1)
10.1056/EVIDoa2400190.
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Eni-Olutu, Ayolola;
Mackie, Nicola E;
Glenn, Jessica;
Bailey, Angela;
Bamford, Alasdair;
Kenny, Julia;
Levin, Leon;
... Foster, Caroline; + view all
(2025)
Emerging integrase resistance in an international perinatal virtual clinic.
AIDS
, 39
(3)
pp. 276-280.
10.1097/QAD.0000000000004048.
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Fernandes, Georgina;
Chappell, Elizabeth;
Goetghebuer, Tessa;
Kahlert, Christian R;
Ansone, Santa;
Bernardi, Stefania;
Castelli Gattinara, Guido;
... Bamford, Alasdair; + view all
(2025)
HIV postnatal prophylaxis and infant feeding policies vary across Europe: results of a Penta survey.
HIV Medicine
, 26
(2)
pp. 207-217.
10.1111/hiv.13723.
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Fronc, Maciej;
Jakubczyk, Michał;
Love, Sharon B;
Talbot, Susan;
Rolfe, Timothy;
(2025)
Central statistical monitoring in clinical trial management: A scoping review.
Clinical Trials
10.1177/17407745241304059.
(In press).
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Gastesi, I;
Domínguez-Rodríguez, S;
Le Prevost, M;
Ramírez, A;
Giaquinto, C;
Mesa, ML;
Ballesteros, A;
... Tagarro, A; + view all
(2025)
Comorbidities Associated With Different Degrees of Severity in Children and Young People Hospitalized With Acute COVID-19.
Pediatric Infectious Disease Journal
10.1097/INF.0000000000004684.
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Gaughan, Charlotte;
Braunholtz, David;
Massie, Leanne;
Khera, Tarnjit;
Birrell, Paul;
Blake, Joshua;
De Angelis, Daniela;
... Walker, Sarah; + view all
(2025)
The cumulative incidence and infection hospitalisation risk of SARS-CoV-2 by variant; a longitudinal study in England.
American Journal of Epidemiology
(In press).
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George, Elizabeth C;
Maitland, Kathryn;
(2025)
Fluid Resuscitation in Pediatric Cerebral Malaria: Insights from the FEAST Trial and Further Evidence from Malawi.
The American Journal of Tropical Medicine and Hygiene
10.4269/ajtmh.25-0132.
(In press).
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Ghafari, Mahan;
Kemp, Steven A;
Hall, Matthew;
Clarke, Joseph;
Ferretti, Luca;
Thomson, Laura;
Studley, Ruth;
... Lythgoe, Katrina; + view all
(2025)
SARS-CoV-2 genomic diversity and within-host evolution
in individuals with persistent infection in the UK: an
observational, longitudinal, population-based surveillance
study.
The Lancet Microbe
(In press).
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Gillessen, Silke;
Turco, Fabio;
Davis, Ian D;
Efstathiou, Jason A;
Fizazi, Karim;
James, Nicholas D;
Shore, Neal;
... Omlin, Aurelius; + view all
(2025)
Management of Patients with Advanced Prostate Cancer. Report from the 2024 Advanced Prostate Cancer Consensus Conference (APCCC).
European Urology
, 87
(2)
pp. 157-216.
10.1016/j.eururo.2024.09.017.
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Gu, Qingze;
Yuan, Kevin;
Wei, Jia;
Yoon, Chang Ho;
Danielsen, Anders S;
Luk, Augustine;
Eyre, David;
(2025)
Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection.
BMC Infectious Diseases
(In press).
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Guglielmetti, Lorenzo;
Khan, Uzma;
Velásquez, Gustavo E;
Gouillou, Maelenn;
Abubakirov, Amanzhan;
Baudin, Elisabeth;
Berikova, Elmira;
... endTB Clinical Trial Team; + view all
(2025)
Oral Regimens for Rifampin-Resistant, Fluoroquinolone-Susceptible Tuberculosis.
New England Journal of Medicine
, 392
(5)
pp. 468-482.
10.1056/NEJMoa2400327.
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Gurumurthy, Meera;
Gopalan, Narendran;
Patel, Leena;
Davis, Andrew;
Srinivasalu, Vignes Anand;
Rajaram, Shakira;
Goodall, Ruth;
... STREAM Trial Collaboration; + view all
(2025)
Treatment outcomes in people with diabetes and multidrug-resistant tuberculosis (MDR TB) enrolled in the STREAM clinical trial.
PLoS Global Public Health
, 5
(4)
, Article e0004259. 10.1371/journal.pgph.0004259.
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Hill, Louise;
Obiero, Christina;
Bekker, Adrie;
Walker, Ann;
Bielick, Julia;
Sharland, Michael;
Schiavone, Francesca;
(2025)
Safety reporting in neonatal clinical trials: reflections towards optimal, globally relevant approaches.
Trials
, 26
, Article 46. 10.1186/s13063-025-08723-y.
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Honda, Trenton;
Vazquez-Montes, Maria DLA;
Fanshawe, Thomas;
Stoesser, Nicole;
Butler, Christopher C;
Walker, Ann;
Hayward, Gail;
(2025)
The impact of inter-infection time on antimicrobial resistance profiles in women with multiple urinary tract infections over time.
Journal of Antimicrobial Chemotherapy
(In press).
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Hopewell, Sally;
Chan, An-Wen;
Collins, Gary S;
Hrobjartsson, Asbjorn;
Moher, David;
Schulz, Kenneth F;
Tunn, Ruth;
... Boutron, Isabelle; + view all
(2025)
CONSORT 2025 Statement: Updated Guideline for Reporting Randomized Trials.
JAMA
10.1001/jama.2025.4347.
(In press).
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Hopewell, Sally;
Chan, An-Wen;
Collins, Gary S;
Hróbjartsson, Asbjørn;
Moher, David;
Schulz, Kenneth F;
Tunn, Ruth;
... Boutron, Isabelle; + view all
(2025)
CONSORT 2025 statement: updated guideline for reporting randomized trials.
Nature Medicine
10.1038/s41591-025-03635-5.
(In press).
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Hopewell, Sally;
Chan, An-Wen;
Collins, Gary S;
Hróbjartsson, Asbjørn;
Moher, David;
Schulz, Kenneth F;
Tunn, Ruth;
... Boutron, Isabelle; + view all
(2025)
CONSORT 2025 explanation and elaboration: updated guideline for reporting randomised trials.
BMJ
, 389
, Article e081124. 10.1136/bmj-2024-081124.
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Hopewell, Sally;
Chan, An-Wen;
Collins, Gary S;
Hróbjartsson, Asbjørn;
Moher, David;
Schulz, Kenneth F;
Tunn, Ruth;
... Boutron, Isabelle; + view all
(2025)
CONSORT 2025 statement: updated guideline for reporting randomised trials.
BMJ
, 389
, Article e081123. 10.1136/bmj-2024-081123.
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Hopewell, Sally;
Chan, An-Wen;
Collins, Gary S;
Hróbjartsson, Asbjørn;
Moher, David;
Schulz, Kenneth F;
Tunn, Ruth;
... Boutron, Isabelle; + view all
(2025)
CONSORT 2025 statement: Updated guideline for reporting randomised trials.
PLOS Medicine
, 22
(4)
, Article e1004587. 10.1371/journal.pmed.1004587.
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Hopewell, Sally;
Chan, An-Wen;
Collins, Gary S;
Hróbjartsson, Asbjørn;
Moher, David;
Schulz, Kenneth F;
Tunn, Ruth;
... Boutron, Isabelle; + view all
(2025)
CONSORT 2025 statement: updated guideline for reporting randomized trials: a Korean translation.
Ewha Medical Journal
, 48
(3)
, Article e50. 10.12771/emj.2025.00409.
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Hróbjartsson, Asbjørn;
Boutron, Isabelle;
Hopewell, Sally;
Moher, David;
Schulz, Kenneth F;
Collins, Gary S;
Tunn, Ruth;
... Chan, An-Wen; + view all
(2025)
SPIRIT 2025 explanation and elaboration: updated guideline for protocols of randomised trials.
BMJ
, 389
, Article e081660. 10.1136/bmj-2024-081660.
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Huynh, Julie;
Chabala, Chishala;
Sharma, Suvasini;
Choo, Louise;
Singh, Varinder;
Sankhyan, Naveen;
Mujuru, Hilda;
... Gibb, Diana M; + view all
(2025)
Effectiveness and safety of shortened intensive treatment for children with tuberculous meningitis (SURE): a protocol for a phase 3 randomised controlled trial evaluating 6 months of antituberculosis therapy and 8 weeks of aspirin in Asian and African children with tuberculous meningitis.
BMJ Open
, 15
(4)
, Article e088543. 10.1136/bmjopen-2024-088543.
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Jackson, Charlotte;
Crichton, Siobhan;
Bamford, Alasdair;
Berzosa Sanchez, Arantxa;
Gilmour, Kimberly C;
Goetghebuer, Tessa;
Johnson, Sarah May;
... Collins, Intira Jeannie; + view all
(2025)
Are children and adolescents living with HIV in Europe and South Africa at higher risk of SARS-CoV-2 and poor COVID-19 outcomes?
Epidemiology and Infection
pp. 1-36.
10.1017/s0950268825000135.
(In press).
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Jackson, Charlotte;
Crichton, Siobhan;
Judd, Ali;
Bamford, Alasdair;
Goulder, Philip;
Klein, Nigel;
Marques, Laura;
... European Pregnancy and Paediatric Infections Cohort, Collaboration; + view all
(2025)
Long-term non-progression in children living with HIV: estimates from international cohort data.
AIDS
10.1097/QAD.0000000000004136.
(In press).
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Kahan, Brennan C;
Juszczak, Edmund;
Beller, Elaine;
Birchenall, Megan;
Chan, An-Wen;
Hall, Sophie;
Little, Paul;
... Montgomery, Alan; + view all
(2025)
Guidance for protocol content and reporting of factorial randomised trials: explanation and elaboration of the CONSORT 2010 and SPIRIT 2013 extensions.
BMJ
, 388
, Article e080785. 10.1136/bmj-2024-080785.
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Katongole, F;
Arumugam, T;
Jennings, A;
Mutata, C;
Ssebunya, P;
Wamboi, C;
Green, A;
... Kabasingo, R; + view all
(2025)
BREATHER Plus clinical trial design: A randomised non-inferiority trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily ART in virologically suppressed adolescents living with HIV aged 12 to <20 years in sub-Saharan Africa.
Contemporary Clinical Trials
, 155
, Article 107963. 10.1016/j.cct.2025.107963.
(In press).
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Kulasegaran-Shylini, Raghavendran;
Bown, Abbie;
Collinge, Tom;
Sienkiewicz, Alex;
Eyre, David W;
Crook, Derrick;
Walker, Sarah;
... Fowler, Tom; + view all
(2025)
Evaluation of SARS-CoV-2 lateral flow device sensitivity: a comparison of systematic laboratory assessments with manufacturer-reported sensitivity.
EClinicalMedicine
(In press).
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Leone, Gianmarco;
Orlando, Francesco;
Dutey-Magni, Peter;
Vainauskas, Osvaldas;
Grist, Emily;
Ciani, Yari;
Lall, Sharanpreet;
... the STAMPEDE collaborators; + view all
(2025)
Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer:
the STAMPEDE Phase 3 Randomized Clinical Trial.
JAMA Oncology
10.1001/jamaoncol.2024.7051.
(In press).
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Leone, Gianmarco;
Wong, Yien Ning Sophia;
Jones, Robert J;
Sankey, Peter;
Josephs, Debra H;
Crabb, Simon J;
Harris, Louise;
... Linch, Mark D; + view all
(2025)
Nivolumab and Ipilimumab for Metastatic Castration-Resistant Prostate Cancer With an Immunogenic Signature: The Multicenter, Two-Cohort, Phase II NEPTUNES Study.
Journal of Clinical Oncology
10.1200/JCO-24-02637.
(In press).
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Lipworth, Samuel;
Chau, Kevin;
Oakley, Sarah;
Barrett, Lucinda;
Crook, Derrick;
Tim, Peto;
Walker, Ann;
(2025)
Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli, an observational study.
The Lancet Microbe
(In press).
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Maitland, Kathryn;
Ouattara, San Maurice;
Sainna, Hadiza;
Chara, Abdullahi;
Ogundipe, Oluwakemi F;
Sunyoto, Temmy;
Hamaluba, M;
... GASTROSAM Trial, Group; + view all
(2025)
Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis.
The New England Journal of Medicine
10.1056/NEJMoa2505752.
(In press).
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Martín-Bejarano García, M;
Jackson, C;
Okhonskaia, L;
Voronin, E;
Rozenberg, V;
Titova, MA;
Kovalenko, T;
... Martinez de Aragón, A; + view all
(2025)
Brain MRI and neurocognitive characteristics of children and adolescents living with HIV.
Child Neuropsychology
10.1080/09297049.2025.2517150.
(In press).
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Matlock, William;
Rodger, Gillian;
Pritchard, Emma;
Colpus, Matthew;
Kapel, Natalia;
Barrett, Lucinda;
Morgan, Marcus;
... Stoesser, Nicole; + view all
(2025)
Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase.
Nature Communications
(In press).
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Mave, V;
Paradkar, M;
Conradie, F;
Gupta, A;
Avihingsanon, A;
Meintjes, G;
Turkova, A;
... Chaisson, RE; + view all
(2025)
Tuberculosis disease among people with HIV: therapeutic advances.
The Lancet HIV
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Second-Line Antiretroviral Therapy for Children Living with HIV in Africa.
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Naidoo, Kogieleum;
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High mortality among patients with tuberculosis accessing primary care facilities: secondary analysis from an open-label cluster-randomised trial.
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Jairath, V;
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Applying the estimand framework to inflammatory bowel disease clinical trials.
The Lancet Gastroenterology and Hepatology
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Developing an adaptive platform trial for evaluation of medical treatments for Crohn's disease.
Nature Reviews Gastroenterology & Hepatology
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Old, Oliver;
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Zimmermann, Alex;
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Barrett’s Oesophagus Surveillance versus endoscopy at need Study (BOSS): a randomized controlled trial.
Gastroenterology
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The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study.
eLife
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Designing a response-over-continuous-interventions (ROCI) randomised trial: Implementation in the phase 2C part (duration ranging) of the PARADIGM4TB trial.
Contemporary Clinical Trials
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Pritchard, Emma;
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An electronic health record-wide association study to identify populations at increased risk of E. coli bacteraemia.
Journal of Infection
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Acceptability of a 250 mg levofloxacin formulation in children receiving TB preventive treatment.
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Risk of Tuberculosis Infection in Young Children Exposed to Multidrug-resistant Tuberculosis in the TB-CHAMP Multi-site Randomized Controlled Trial.
Clinical Infectious Diseases
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Timeliness of a potential automated system for national surveillance of healthcare-associated infections in England.
Journal of Hospital Infection
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Refining Risk Stratification of High-risk and Locoregional Prostate Cancer: A Pooled Analysis of Randomized Trials.
European Urology
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10.1016/j.eururo.2024.04.038.
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Rodger, G;
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Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in twenty-nine UK hospitals.
Journal of Hospital Infection
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Roland, Damian;
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Evidence of Poor Utility of Current Sepsis Screening Tools in an At-Risk Population of Children With Community-Acquired Pneumonia.
Pediatric Infectious Disease Journal
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Estimating the Opportunity for Early Detection of Ovarian Cancer Using Individual-Patient Data from a Large Randomized Controlled Trial.
Cancer Epidemiology, Biomarkers & Prevention
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Extended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
British Journal of Surgery
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Sharing clinical trial results with participants: important, expected and possible.
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Clinicians in low- and middle-income settings need better access to point-of-care haemoglobin tests for identifying and managing children and pregnant women with severe anaemia.
Tropical Medicine & International Health
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Developing a knowledge transfer and exchange strategy for a clinical trials unit.
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Tatoud, Roger;
Levy, Yves;
Le Grand, Roger;
Alcami, Jose;
Barbareschi, Giorgio;
Brander, Christian;
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(2025)
In danger: HIV vaccine research and development in Europe.
PLOS Global Public Health
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Fisher, David J;
Higgins, Julian PT;
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Anticoagulation Among Patients Hospitalized for COVID-19: A Systematic Review and Prospective Meta-analysis.
Annals of Internal Medicine
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Master protocol for a series of cohort-based randomized controlled trials to test tools to communicate research results to study participants and others with relevant lived experience: the SPIN-CLEAR Trials.
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The development of a conceptual framework and method to determine whether doctors’ responses to patients’ concerns are patient-centred.
Doctoral thesis (Ph.D), UCL (University College London).
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Peñalvo, José Luis;
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Davis, Ruth Joanna;
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Lessons from the European Mpox Outbreak: Strengthening Cohort Research for Future Pandemic Preparedness.
Clinical Microbiology and Infection
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Simplifying medicine dosing for children by harmonising weight bands across therapeutic areas.
The Lancet Child & Adolescent Health
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Executive Dysfunction and Disability in SPMS: Predictive
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MS-STAT2 Cohort.
European Journal of Neurology
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Community-acquired pneumonia identification from electronic health records in the absence of a gold standard: a Bayesian latent class analysis.
PLoS Digital Health
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Advancing the chemotherapy of tuberculous meningitis: a consensus view.
The Lancet Infectious Diseases
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White, Ellen;
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Virological outcomes and genotypic resistance on dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial.
The Lancet HIV
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Tackling control risk problems in non-inferiority trials.
BMJ Medicine
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Distinct neural networks of emotional valence and uncertainty in the human amygdala underlying different mental disorders.
Science Bulletin
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Machine learning and clinician predictions of antibiotic resistance in Enterobacterales bloodstream infections.
Journal of Infection
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Yuan, Kevin;
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Gu, Qingze;
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Transformers and large language models are efficient feature extractors for electronic health record studies.
Communications Medicine
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Zwerwer, Leslie R;
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Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories.
Nature Communications
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Abdalla, Seef;
Compagnucci, Alexandra;
Riault, Yoann;
Chan, Man K;
Bamford, Alasdair;
Nolan, Aoife;
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Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial.
Antimicrobial Agents and Chemotherapy
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Abrego, Luis;
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Jacobs, Ian;
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Bayesian and deep-learning models applied to the early detection of ovarian cancer using multiple longitudinal biomarkers.
Cancer Medicine
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Al Wattar, Bassel H;
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Effectiveness of treatment options for tubal ectopic pregnancy: A systematic review and network meta-analysis.
BJOG: an International Journal of Obstetrics and Gynaecology
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Effectiveness and safety of menopause treatments: pitfalls of available evidence and future research need.
Climacteric
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Alagaratnam, J;
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Impact of interrupting antiretroviral therapy started during primary HIV-1 infection on plasma neurofilament light chain protein, a marker of neuronal injury: The SPARTAC trial.
Journal of Virus Eradication
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Alkhmees, M;
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Trends in C-Reactive Protein testing: a retrospective cohort study in paediatric ambulatory care settings.
BMJ Open
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AMR-X Collaborators;
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The Lancet Microbe
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Pre-hospital transdermal glyceryl trinitrate for transient ischaemic attack: Data from the RIGHT-2 trial.
European Journal of Neurology
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Ayoubkhani, Daniel;
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Employment outcomes of people with Long Covid symptoms: community-based cohort study.
European Journal of Public Health
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Bhatty, Asad;
Wilkinson, Chris;
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Defining the need for cardiovascular event definitions.
European Heart Journal - Quality of Care and Clinical Outcomes
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The predictive role of symptoms in COVID-19
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Epidemiology and Infection
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Borek, Aleksandra;
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Stop antibiotics when you feel better? Opportunities, challenges and research directions.
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Brenner, IR;
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Cost-effectiveness of viral load testing for transitioning antiretroviral therapy-experienced children to dolutegravir in South Africa: a modelling analysis.
The Lancet Global Health
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Nanopore sequencing of influenza A and B in Oxfordshire and the United Kingdom, 2022–23.
Journal of Infection
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Carter, Joshua;
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Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches.
JAC-Antimicrobial Resistance
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Cevik, Muge;
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Malahleha, Mookho;
Mmbaga, Blandina;
Ngubane, Nosipho;
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Bedaquiline-pretomanid-moxifloxacin-pyrazinamide for drug-sensitive and drug-resistant pulmonary tuberculosis treatment: a phase 2c, open-label, multicentre, partially randomised controlled trial.
The Lancet Infectious Diseases
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Clinical outcomes in children living with HIV treated for non-severe tuberculosis in the SHINE Trial.
Clinical Infectious Diseases
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Chen, Yang;
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Rationale and design of the THIRST Alert feasibility study: a pragmatic, single-centre, parallel-group randomised controlled trial of an interruptive alert for oral fluid restriction in patients treated with intravenous furosemide.
BMJ Open
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Chiang, CY;
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Radiographic characteristics of rifampicin-resistant tuberculosis in the STREAM stage 1 trial and their influence on time to culture conversion in the short regimen.
BMC Infectious Diseases
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Choodari-Oskooei, Babak;
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Designing a platform/adaptive randomised controlled trial for peripheral arterial disease (PAD) – The PAEDIS international platform trial development project.
NIHR Open Research
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Choodari-Oskooei, Babak;
Parmar, Mahesh KB;
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Multi-arm multi-stage (MAMS) randomised selection designs: impact of treatment selection rules on the operating characteristics.
BMC Medical Research Methodology
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Burns, Fiona M;
Wright, Talen;
Samba, Phil;
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Nicholls, Emily Jay;
McCabe, Leanne;
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How can HIV self-testing facilitate increased access to HIV testing among multiply marginalised populations? Perspectives from GBMSM and trans women in England and Wales.
PLoS ONE
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Connon, Roisin;
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Muhindo, Rita;
Uyoga, Sophie;
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Azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a Phase II randomised controlled trial.
BMC Medicine
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Cox, Nicholas J;
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Stage at Diagnosis Following Delay to Interval Scans for Indeterminate Nodules in Lung Cancer Screening: An Observational Study Examining the Outcomes of CHEST Expert Panel Recommendations.
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Cressey, TR;
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Expanding options of child-friendly, single-tablet regimens for young children with HIV.
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Development and validation of the Baseline Recurrence Risk in Cellulitis (BRRISC) score.
Journal of Infection
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Tyrer, Jonathan P;
Peng, Pei-Chen;
Rosenow, Will;
Chen, Stephanie;
Davis, Brian D;
... Gayther, Simon A; + view all
(2024)
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions.
American Journal of Human Genetics
, 111
(6)
pp. 1061-1083.
10.1016/j.ajhg.2024.04.011.
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Dashti, S Ghazaleh;
Lee, Katherine J;
Simpson, Julie A;
White, Ian R;
Carlin, John B;
Moreno-Betancur, Margarita;
(2024)
Handling missing data when estimating causal effects
with targeted maximum likelihood estimation.
American Journal of Epidemiology
, Article kwae012. 10.1093/aje/kwae012.
(In press).
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Dexter, JM;
Brubaker, LW;
Bitler, BG;
Goff, BA;
Menon, U;
Moore, KN;
Sundaram, KM;
... Behbakht, K; + view all
(2024)
Ovarian cancer think tank: An overview of the current status of ovarian cancer screening and recommendations for future directions.
Gynecologic Oncology Reports
, 53
, Article 101376. 10.1016/j.gore.2024.101376.
(In press).
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Di Chiara, Costanza;
Cantarutti, Anna;
Raffaella Petrara, Maria;
Bonfante, Francesco;
Benetti, Elisa;
Boracchini, Riccardo;
Bosa, Luca;
... Padoan, Andrea; + view all
(2024)
Stronger and durable SARS-CoV-2 immune response to mRNA vaccines in 5–11 years old children with prior COVID-19.
Vaccine
, 42
(2)
pp. 263-270.
10.1016/j.vaccine.2023.12.006.
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Drury, Thomas;
Abellan, Juan J;
Best, Nicky;
White, Ian R;
(2024)
Estimation of Treatment Policy Estimands for Continuous Outcomes Using Off-Treatment Sequential Multiple Imputation.
Pharmaceutical Statistics
10.1002/pst.2411.
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Dufault, SM;
Crook, AM;
Rolfe, K;
Phillips, PPJ;
(2024)
A flexible multi-metric Bayesian framework for decision-making in Phase II multi-arm multi-stage studies.
Statistics in Medicine
, 43
(3)
pp. 501-513.
10.1002/sim.9961.
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Evrenoglou, Theodoros;
Metelli, Silvia;
Thomas, Johannes‐Schneider;
Siafis, Spyridon;
Turner, Rebecca M;
Leucht, Stefan;
Chaimani, Anna;
(2024)
Sharing information across patient subgroups to draw conclusions from sparse treatment networks.
Biometrical Journal
, 66
(3)
, Article 2200316. 10.1002/bimj.202200316.
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Fabiane, SM;
Chiang, CY;
Meredith, SK;
Gurumurthy, M;
Bayissa, A;
Nunn, AJ;
Goodall, RL;
(2024)
Comparative Efficacy and Safety of Moxifloxacin and Levofloxacin in a Short Standardised Rifampicin Resistant TB Regimen: A STREAM 2 Secondary Analysis.
Tropical Medicine and Infectious Disease
, 9
(9)
, Article 211. 10.3390/tropicalmed9090211.
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Fabiane, Stella Maris;
Hakiman, Assica;
Schumacher, Samuel;
Mirzayev, Fuad;
Rangaka, Lele;
Goodall, Ruth;
(2024)
Data sharing experiences from the publicly accessible WHO TB-IPD platform.
Presented at: 7th International Clinical Trials Methodology Conference (ICTMC), Edinburgh, UK.
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Forster, Martin;
Brana, Irene;
Lopez Pousa, Antonio;
Doger, Bernard;
Roxburgh, Patricia;
Bajaj, Pawan;
Peguero, Julio;
... Triebel, Frederic; + view all
(2024)
Eftilagimod Alpha (Soluble LAG3 Protein) Combined with Pembrolizumab as Second-Line Therapy for Patients with Metastatic Head and Neck Squamous Cell Carcinoma.
Clinical Cancer Research
, 30
(17)
pp. 3726-3734.
10.1158/1078-0432.CCR-24-0473.
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Frangou, Eleni;
Choodari-Oskooei, Babak;
Parmar, Mahesh;
Meade, Angela;
RAMPART Trial Team;
(2024)
Navigating through the re-design of a multi-arm, multi-stage (MAMS) trial in light of external data.
Presented at: International Conference of Trial Methodology (ICTMC) 2024, Edinburgh, UK.
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Fritschi, Nora;
Gureva, Tatyana;
Eliseev, Platon;
Jackson, Charlotte;
Milanzi, Edith;
Crichton, Siobhan;
Collins, Intira Jeannie;
... Ritz, Nicole; + view all
(2024)
Diagnosis of tuberculosis infection in children
with a novel skin test and the traditional
tuberculin skin test: An observational study.
PLoS ONE
, 19
(8)
, Article e0293272. 10.1371/journal.pone.0293272.
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Ghafari, Mahan;
Hall, Matthew;
Golubchik, Tanya;
Ayoubkhani, Daniel;
House, Thomas;
MacIntyre-Cockett, George;
Fryer, Helen R;
... Lythgoe, Katrina; + view all
(2024)
Prevalence of persistent SARS-CoV-2 in
a large community surveillance study.
Nature
, 626
pp. 1094-1101.
10.1038/s41586-024-07029-4.
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Givens, Matthew;
Valcheva, Ivaila;
Einerson, Brett D;
Rogozinska, Ewelina;
Jauniaux, Eric;
(2024)
Evaluation of maternal serum protein biomarkers in the prenatal evaluation of placenta accreta spectrum: A systematic scoping review.
Acta Obstetricia et Gynecologica Scandinavica
, 103
(12)
pp. 2335-2347.
10.1111/aogs.14918.
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Glasbey, J;
Beggs, A;
Glimelius, B;
Gray, R;
Handley, K;
Laurberg, S;
Magill, L;
... Furniss, D; + view all
(2024)
Risk of Bowel Obstruction in Patients Undergoing Neoadjuvant Chemotherapy for High-risk Colon Cancer: A Nested Case-control-matched Analysis of an International, Multicenter, Randomized Controlled Trial (FOxTROT).
Annals of Surgery
, 280
(2)
pp. 283-293.
10.1097/SLA.0000000000006145.
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Goodall, RL;
Fabiane, SM;
Hakiman, A;
Crook, AM;
Mirzayev, F;
Schumacher, S;
Rangaka, MX;
(2024)
A publicly accessible global data repository - the WHO TB-IPD platform.
IJTLD Open
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(4)
pp. 151-153.
10.5588/ijtldopen.24.0131.
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Goodall, Ruth L;
Nunn, Andrew J;
Meredith, Sarah K;
Bayissa, Adamu;
Bhatnagar, Anuj K;
Chiang, Chen-Yuan;
Conradie, Francesca;
... STREAM study collaborators; + view all
(2024)
Long-term efficacy and safety of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): extended follow-up of an open-label, multicentre, randomised, non-inferiority trial.
The Lancet Respiratory Medicine
10.1016/S2213-2600(24)00186-3.
(In press).
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Gu, Qingze;
Wei, Jia;
Yoon, Chang Ho;
Yuan, Kevin;
Jones, Nicola;
Brent, Andrew;
Llewelyn, Martin;
... Walker, A Sarah; + view all
(2024)
Distinct patterns of vital sign and inflammatory marker responses in adults with suspected bloodstream infection.
Journal of Infection
, 88
(5)
, Article 106156. 10.1016/j.jinf.2024.106156.
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Gupta, Neil;
Hiebert, Lindsey;
Saseetharran, Ankeeta;
Chappell, Catherine;
El-Sayed, Manal H;
Hamid, Saeed;
Jhaveri, Ravi;
... Ward, John W; + view all
(2024)
Best practices for hepatitis C linkage to care in pregnant and postpartum women: perspectives from the Treatment In Pregnancy for Hepatitis C Community of Practice.
American Journal of Obstetrics and Gynecology
, 231
(4)
pp. 377-385.
10.1016/j.ajog.2024.06.028.
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Gurusamy, Kurinchi;
Leung, Jeffrey;
Vale, Claire;
Roberts, Danielle;
Linden, Audrey;
Tan, Xiao Wei;
Taribagil, Priyal;
... ODwyer, Sarah T; + view all
(2024)
Cytoreductive surgery plus hyperthermic intraoperative peritoneal chemotherapy for people with peritoneal metastases from colorectal, ovarian or gastric origin: A systematic review of randomized controlled trials.
World Journal of Surgery
10.1002/wjs.12186.
(In press).
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Hachicha-Maalej, Nadia;
Lepers, Clotilde;
Collins, Intira Jeannie;
Mostafa, Aya;
Ades, Anthony E;
Judd, Ali;
Scott, Karen;
... Deuffic-Burban, Sylvie; + view all
(2024)
Modelling the potential clinical and economic impact of universal antenatal hepatitis C (HCV) screening and providing treatment for pregnant women with HCV and their infants in Egypt: a cost-effectiveness study.
BMJ Public Health
, 2
(1)
, Article e000517. 10.1136/bmjph-2023-000517.
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Halabi, Susan;
Guo, Siyuan;
Roy, Akash;
Rydzewska, Larysa E;
Godolphin, Peter;
Hussain, Maha;
Tangen, Catherine;
... Sweeney, Christopher J; + view all
(2024)
Reply to J.A. Garcia et al.
[Letter].
Journal of Clinical Oncology
, 42
(24)
pp. 2940-2943.
10.1200/JCO.24.00625.
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Halabi, Susan;
Roy, Akash;
Rydzewska, Larysa;
Guo, Siyuan;
Godolphin, Peter;
Hussain, Maha;
Tangen, Catherine;
... STOPCAP/ICECaP, Collaboration; + view all
(2024)
Radiographic Progression-Free Survival and Clinical Progression-Free Survival as Potential Surrogates for Overall Survival in Men With Metastatic Hormone-Sensitive Prostate Cancer.
Journal of Clinical Oncology
10.1200/JCO.23.01535.
(In press).
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Hamada, Yohhei;
Quartagno, Matteo;
Law, Irwin;
Malik, Farihah;
Bonsu, Frank Adae;
Adetifa, Ifedayo MO;
Adusi-Poku, Yaw;
... Rangaka, Molebogeng X; + view all
(2024)
Tobacco smoking clusters in households affected by tuberculosis in an individual participant data meta-analysis of national tuberculosis prevalence surveys: Time for household-wide interventions?
PLOS Global Public Health
, 4
(2)
, Article e0002596. 10.1371/journal.pgph.0002596.
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Hemming, Karla;
Thompson, Jacqueline Y;
Taljaard, Monica;
Watson, Samuel I;
Kasza, Jessica;
Thompson, Jennifer A;
Kahan, Brennan C;
(2024)
Re-analysis of data from cluster randomised trials to explore the impact of model choice on estimates of odds ratios: study protocol.
Trials
, 25
(1)
, Article 818. 10.1186/s13063-024-08653-1.
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Hesseling, AC;
Purchase, SE;
Martinson, NA;
Fairlie, L;
Schaaf, HS;
Brigden, J;
Staples, S;
... Seddon, JA; + view all
(2024)
Levofloxacin Preventive Treatment in Children Exposed to MDR Tuberculosis.
New England Journal of Medicine
, 391
(24)
pp. 2315-2326.
10.1056/NEJMoa2314318.
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Hughes, Gareth;
Young, William J;
Bern, Henry;
Crook, Angela;
Lambiase, Pier D;
Goodall, Ruth L;
Nunn, Andrew J;
(2024)
T-wave morphology abnormalities in the STREAM stage 1 trial.
Expert Opinion on Drug Safety
, 23
(4)
pp. 469-476.
10.1080/14740338.2024.2322116.
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Illah, Ojone;
Adeeko, Deborah;
Olaitan, Adeola;
Gentry-Maharaj, Aleksandra;
(2024)
Racioethnic Disparities in Endometrial Cancer Outcomes.
Diagnostics
, 14
(4)
, Article 417. 10.3390/diagnostics14040417.
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Iyizoba-Ebozue, Z;
Fatimilehin, A;
Kayani, M;
Khan, A;
McMahon, M;
Stewart, S;
Croney, C;
... O'Reilly, K; + view all
(2024)
Unveiling Disparities: Exploring Differential Attainment in Postgraduate Training Within Clinical Oncology.
Clinical Oncology
10.1016/j.clon.2024.03.021.
(In press).
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Jacobs, Tom;
Waalewijn, Hylke;
Houlden, Lily;
Bollen, Pauline;
Nanduudu, Annet;
Nambi, Esether;
Cassim, Haseena;
... Colbers, Angela; + view all
(2024)
Influence of age and co-medication on dolutegravir glucuronidation in paediatric patients.
British Journal of Clinical Pharmacology
, Article e16238. 10.1111/bcp.16238.
(In press).
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James, Nicholas D;
Tannock, Ian;
N'Dow, James;
Feng, Felix;
Gillessen, Silke;
Ali, Syed Adnan;
Trujillo, Blanca;
... Xie, Li-Ping; + view all
(2024)
The Lancet Commission on prostate cancer: planning for the surge in cases.
The Lancet
10.1016/S0140-6736(24)00651-2.
(In press).
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Janrode, N;
Hamada, Y;
Taliep, A;
Goliath, R;
Duong, T;
Jackson, A;
Galant, S;
... Rangaka, MX; + view all
(2024)
Sensitivity and Specificity of Tuberculosis Screening Tools in People with Diabetes (OA51-510-16).
Presented at: Union World Conference on Lung Health 2024, Bali, Indonesia.
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Kahan, Brennan C;
Blette, Bryan S;
Harhay, Michael O;
Halpern, Scott D;
Jairath, Vipul;
Copas, Andrew;
Li, Fan;
(2024)
Demystifying estimands in cluster-randomised trials.
Statistical Methods in Medical Research
10.1177/09622802241254197.
(In press).
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Kahan, Brennan C;
Hindley, Joanna;
Edwards, Mark;
Cro, Suzie;
Morris, Tim P;
(2024)
The estimands framework: a primer on the ICH E9(R1) addendum.
BMJ
, 384
, Article e076316. 10.1136/bmj-2023-076316.
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Kakaraskoska Boceska, Biljana;
Vilken, Tuba;
Xavier, Basil Britto;
Kostyanev, Tomislav;
Lin, Qiang;
Lammens, Christine;
Ellis, Sally;
... Goossens, Herman; + view all
(2024)
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries.
Nature Communications
, 15
, Article 3947. 10.1038/s41467-024-48296-z.
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Kansiime, Sheila;
Hansen, Christian Holm;
Ruzagira, Eugene;
Mccormack, Sheena;
Hayes, Richard;
Dunn, David;
PrEPVacc, Study Team;
(2024)
Challenges in estimating the counterfactual placebo HIV incidence rate from a registration cohort: The PrEPVacc trial.
Clinical Trials
, 22
(3)
289 -300.
10.1177/17407745241304721.
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Keshtkar-Jahromi, Maryam;
Anstrom, Kevin J;
Barkauskas, Christina;
Brown, Samuel M;
Daar, Eric S;
Fischer, William;
Gibbs, Kevin W;
... Adam, Stacey J; + view all
(2024)
ACTIV trials: Lessons learned in trial design in the setting of an emergent pandemic.
Journal of Clinical and Translational Science
, 8
(1)
, Article e151. 10.1017/cts.2024.1.
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Kusemererwa, Sylvia;
Kansiime, Sheila;
Nakamanya, Sarah;
Mbabazi, Elizabeth;
Fox, Julie;
Mccormack, Sheena;
Kaleebu, Pontiano;
(2024)
Contraceptive use, prevalence and incidence of pregnancy and associated factors among women participating in a vaccine preparedness cohort study in Masaka, Uganda, a retrospective secondary analysis.
Reproductive Health
, 21
(1)
, Article 199. 10.1186/s12978-024-01942-7.
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Kwak, Lucia;
Ravi, Praful;
Armstrong, John G;
Beckendorf, Veronique;
Chin, Joseph L;
D'Amico, Anthony V;
Dearnaley, David P;
... Sweeney, Christopher J; + view all
(2024)
Prognostic Impact of Prostate-Specific Antigen at 6 Months After Radiotherapy in Localized Prostate Cancer: An Individual Patient Data Analysis of Randomized Trials.
Journal of Clinical Oncology
, 42
(18)
pp. 2132-2138.
10.1200/JCO.23.00762.
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Kwong, Fong Lien;
Kristunas, Caroline;
Davenport, Clare;
Aggarwal, Ridhi;
Deeks, Jon;
Mallett, Sue;
Kehoe, Sean;
... ROCkeTS collaborators; + view all
(2024)
Investigating harms of testing for ovarian cancer – psychological outcomes and cancer conversion rates in women with symptoms of ovarian cancer: A cohort study embedded in the multicentre ROCkeTS prospective diagnostic study.
BJOG: An International Journal of Obstetrics and Gynaecology
10.1111/1471-0528.17813.
(In press).
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Kwong, Fong Lien Audrey;
Kristunas, Caroline;
Davenport, Clare;
Deeks, Jon;
Mallett, Sue;
Agarwal, Ridhi;
Kehoe, Sean;
... ROCkeTS collaborators; + view all
(2024)
Symptom-triggered testing detects early stage and low volume resectable advanced stage ovarian cancer.
International Journal of Gynecologic Cancer
10.1136/ijgc-2024-005371.
(In press).
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Landovitz, Raphael J;
Tao, Li;
Yang, Juan;
de Boer, Melanie;
Carter, Christoph;
Das, Moupali;
Baeten, Jared M;
... Global F/TDF PrEP Study Team; + view all
(2024)
Type 1 Human Immunodeficiency Virus (HIV-1) Incidence, Adherence, and Drug Resistance in Individuals Taking Daily Emtricitabine/Tenofovir Disoproxil Fumarate for HIV-1 Pre-exposure Prophylaxis: Pooled Analysis From 72 Global Studies.
Clinical Infectious Diseases
, Article ciae143. 10.1093/cid/ciae143.
(In press).
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Lau, Chung-Ho E;
Manou, Maria;
Markozannes, Georgios;
Ala-Korpela, Mika;
Ben-Shlomo, Yoav;
Chaturvedi, Nish;
Engmann, Jorgen;
... Robinson, Oliver; + view all
(2024)
NMR metabolomic modeling of age and lifespan: A multicohort analysis.
Aging Cell
, Article e14164. 10.1111/acel.14164.
(In press).
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Le Prevost, M;
Judd, A;
Crichton, S;
Foster, C;
Bamford, A;
Ford, D;
Gibb, D;
... Driver, B; + view all
(2024)
Factors associated with engagement in HIV care for young people living with perinatally acquired HIV in England: An exploratory observational cohort study.
PLoS ONE
, 19
(5)
, Article e0302601. 10.1371/journal.pone.0302601.
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Lensen, Sarah;
Sydes, Matthew R;
Polyakov, Alex;
Wilkinson, Jack;
(2024)
When to randomize patients in a randomized controlled trial?
Fertility and Sterility
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(6)
pp. 902-904.
10.1016/j.fertnstert.2024.03.008.
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Limkin, Elaine;
Blanchard, Pierre;
Lacas, Benjamin;
Bourhis, Jean;
Parmar, Mahesh;
Licitra, Lisa;
Le, Quynh-Thu;
... MACH-NC* and MARCH** collaborative groups; + view all
(2024)
Season of radiotherapy and outcomes of head & neck cancer patients in the MACH-NC & MARCH meta-analyses.
Radiotherapy & Oncology
, 190
, Article 110011. 10.1016/j.radonc.2023.110011.
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Lipworth, Samuel;
Crook, Derrick;
Walker, Ann;
Peto, Tim;
Stoesser, Nicole;
(2024)
Exploring uncatalogued genetic variation in antimicrobial resistance gene families in Escherichia coli: an observational analysis.
The Lancet Microbe
, 5
(11)
, Article 100913. 10.1016/S2666-5247(24)00152-6.
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Lipworth, Samuel;
Matlock, William;
Shaw, Liam;
Vihta, Karina-Doris;
Rodger, Gillian;
Chau, Kevin;
Barker, Leanne;
... Stoesser, Nicole; + view all
(2024)
The plasmidome associated with Gram-negative bloodstream infections: A large-scale observational study using complete plasmid assemblies.
Nature Communications
, 15
, Article 1612. 10.1038/s41467-024-45761-7.
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Liu, Aoxing;
Genovese, Giulio;
Zhao, Yajie;
Pirinen, Matti;
Zekavat, Seyedeh M;
Kentistou, Katherine A;
Yang, Zhiyu;
... Wolk, Alicja; + view all
(2024)
Genetic drivers and cellular selection of female mosaic X chromosome loss.
Nature
, 631
pp. 134-141.
10.1038/s41586-024-07533-7.
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Lunny, Carole;
Veroniki, Areti-Angeliki;
Higgins, Julian PT;
Dias, Sofia;
Hutton, Brian;
Wright, James M;
White, Ian R;
... Tricco, Andrea C; + view all
(2024)
Methodological review of NMA bias concepts provides groundwork for the development of a list of concepts for potential inclusion in a new risk of bias tool for network meta-analysis (RoB NMA Tool).
Systematic Reviews
, 13
, Article 25. 10.1186/s13643-023-02388-x.
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Mainzer, RM;
Nguyen, CD;
Carlin, JB;
Moreno-Betancur, M;
White, IR;
Lee, KJ;
(2024)
A comparison of strategies for selecting auxiliary variables for multiple imputation.
Biometrical Journal
, 66
(1)
, Article 2200291. 10.1002/bimj.202200291.
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Maitland, K;
Obonyo, N;
Hamaluba, M;
Ogoda, E;
Mogaka, C;
Williams, TN;
Newton, C;
... George, EC; + view all
(2024)
A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)
[version 1; peer review: 2 approved].
Wellcome Open Research
, 9
, Article 281. 10.12688/wellcomeopenres.21403.1.
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Maitland, Kathryn;
Hamaluba, Mainga;
Obonyo, Nchafatso;
Oguda, Emmanuel;
Mogoka, Christabel;
Williams, Thomas N;
Chaponda, Mike;
... Severe Malaria in African Children A Research and Trials (SMAART; + view all
(2024)
SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART).
Wellcome Open Research
, 8
p. 484.
10.12688/wellcomeopenres.20111.2.
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Makumbi, Shafic;
Bajunirwe, Francis;
Ford, Deborah;
Turkova, Anna;
South, Annabelle;
Lugemwa, Abbas;
Musiime, Victor;
... Tamwesigire, Imelda K; + view all
(2024)
Voluntariness of consent in paediatric HIV clinical trials: a mixed-methods, cross-sectional study of participants in the CHAPAS-4 and ODYSSEY trials in Uganda.
BMJ Open
, 14
(3)
, Article e077546. 10.1136/bmjopen-2023-077546.
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Malik, Farihah;
Crichton, Siobhan;
Plotnikova, Yulia;
Latysheva, Inga;
Samarina, Anna;
Pokorska-Śpiewak, Maria;
Gomez, Marisa Navarro;
... Collins, Intira Jeannie; + view all
(2024)
Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe.
The Pediatric Infectious Disease Journal
10.1097/INF.0000000000004271.
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Martin, RM;
Turner, EL;
Young, GJ;
Metcalfe, C;
Walsh, EI;
Lane, JA;
Sterne, JAC;
... Donovan, JL; + view all
(2024)
Prostate-Specific Antigen Screening and 15-Year Prostate Cancer Mortality: A Secondary Analysis of the CAP Randomized Clinical Trial.
JAMA: Journal of the American Medical Association
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pp. 1460-1470.
10.1001/jama.2024.4011.
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Mathers, Amy;
Li, Thomas;
He, Qijan;
Narendra, Sharvari;
Stoesser, Nicole;
Eyre, David;
Walker, Ann;
... Reidys, Christian; + view all
(2024)
Developing a framework for tracking antimicrobial resistance gene movement in a persistent environmental reservoir.
npj Antimicrobials and Resistance
, 2
, Article 50. 10.1038/s44259-024-00069-w.
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Mathur, Shrey;
Smuk, Melanie;
Evans, Ceri;
Wedderburn, Catherine J;
Gibb, Diana M;
Penazzato, Martina;
Prendergast, Andrew J;
(2024)
Estimating the impact of alternative programmatic cotrimoxazole strategies on mortality among children born to mothers with HIV: A modelling study.
PLOS Medicine
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(In press).
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McCormack, Mary;
Eminowicz, Gemma;
Gallardo, Dolores;
Diez, Patricia;
Farrelly, Laura;
Kent, Christopher;
Hudson, Emma;
... Ledermann, Jonathan Andrew; + view all
(2024)
Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE): an international, multicentre, randomised phase 3 trial.
The Lancet
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Larkin, James;
Powles, Tom;
Stewart, Grant D;
Albiges, Laurence;
... Parmar, Mahesh KB; + view all
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Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.
Contemporary Clinical Trials Communications
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Rush, Hannah L;
Daniels, Susanna;
Fielding, Alison;
Deveson Kell, Sharon;
Pickering, Lisa;
Langley, Ruth E;
... Gilbert, Duncan C; + view all
(2024)
Hit it hard: qualitative patient perspectives on the optimisation of immune checkpoint inhibition.
British Journal of Cancer
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Mittal, Prabal;
Gafoor, Rafael;
Sayar, Zara;
Efthymiou, Maria;
Tohidi-Esfahani, Ibrahim;
Appiah-Cubi, Stella;
Arachchillage, Deepa J;
... Cohen, Hannah; + view all
(2024)
Rivaroxaban for stroke patients with antiphospholipid syndrome (RISAPS): protocol for a randomized controlled, phase IIb proof-of-principle trial.
Research and Practice in Thrombosis and Haemostasis
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Moore, Amelia EB;
Burns, James E;
Sally, Deirdre;
Milinkovic, Ana;
Krokos, Georgios;
John, Joemon;
Rookyard, Christopher;
... Pett, Sarah L; + view all
(2024)
Bone turnover change after randomized switch from tenofovir disoproxil to tenofovir alafenamide fumarate in men with HIV.
AIDS
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Morris, Tim P;
White, Ian R;
Cro, Suzie;
Bartlett, Jonathan W;
Carpenter, James R;
Pham, Tra My;
(2024)
Comment on Oberman & Vink: Should we fix or simulate the complete data in simulation studies evaluating missing data methods?
Biometrical Journal
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Muñoz Muñoz, Candido;
Farinha, Filipa;
McDonnell, Thomas;
J'bari, Hajar;
Nguyen, Hanh;
Isenberg, David;
Rahman, Anisur;
... Giles, Ian; + view all
(2024)
Comparing pregnancy outcomes in patients with Systemic Lupus Erythematosus (SLE) and Undifferentiated Connective Tissue Disease (UCTD): a descriptive cohort study.
Revista Clínica Española: Journal of Internal Medicine
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10.1016/j.rceng.2024.04.013.
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Naghavi, M;
Vollset, SE;
Ikuta, KS;
Swetschinski, LR;
Gray, AP;
Wool, EE;
Robles Aguilar, G;
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(2024)
Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050.
The Lancet
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Hamilton, P;
Phung, MT;
Milne, K;
Harris, B;
Thornton, S;
Stevens, D;
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(2024)
Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer.
Journal of Clinical Investigation
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Newton, Claire;
Graham, Radha;
Liberale, Viola;
Burnell, Matthew;
Menon, Usha;
Mould, Tim;
Olaitan, Adeola;
... Manchanda, Ranjit; + view all
(2024)
Outcomes of minimal access retroperitoneal para-aortic lymphadenectomy in patients with locally advanced cervical cancer.
Journal of Obstetrics and Gynaecology
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Ney, Alexander;
Nené, Nuno R;
Sedlak, Eva;
Acedo, Pilar;
Blyuss, Oleg;
Whitwell, Harry J;
Costello, Eithne;
... Pereira, Stephen P; + view all
(2024)
Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection.
PLoS Computatonial Biology
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Nicholas, Richard;
Knowles, Sarah;
Drescher, Sonja;
Craig, Elaine;
Pugh, Cheryl;
Braisher, Marie;
Tallantyre, Emma;
... Middleton, Rod; + view all
(2024)
The external validity of the multi-arm multi-stage OCTOPUS trial in progressive MS: recruitment phase.
Presented at: 40th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), Copenhagen, Denmark.
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Nicholson, Lily;
Axon, Emma;
Daru, Jahnavi;
Rogozińska, Ewelina;
(2024)
Effect and safety of intravenous iron compared to oral iron for treatment of iron deficiency anaemia in pregnancy.
Cochrane Database of Systematic Reviews
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Aloroker, Florence;
Mpoya, Ayub;
Mnjalla, Hellen;
Paasi, George;
Nakuya, Margaret;
Houston, Kirsty;
... Maitland, Kathryn; + view all
(2024)
Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol [version 2; peer review: 2 approved].
Wellcome Open Research
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Palmer, M;
van der Zalm, MM;
Schaaf, HS;
Goussard, P;
Morrison, J;
Seddon, JA;
Hissar, S;
... Hesseling, AC; + view all
(2024)
Approaches and processes for paediatric chest X-ray classification used in the SHINE TB treatment-shortening trial.
International Journal of Tuberculosis and Lung Disease
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Bhan, Anant;
Rodrigues, Rashmi;
Menon, Usha;
(2024)
Trials Methodology Research: what is it and why should India invest in it?
The Lancet Regional Health - Southeast Asia
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Paredes, JL;
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McAlpine, C;
Matthews, R;
Milinkovic, A;
Suonpera, E;
(2024)
Depression is associated with poor self-reported adherence to antiretroviral therapy among people living with HIV attending an HIV clinic in the UK: results from a cross-sectional study.
AIDS Care
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Parker, CC;
Catton, CN;
Clarke, N;
Meidahl, P;
Parmar, M;
Parulekar, W;
Sydes, M;
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Reply to "Letter to the Editor regarding "Timing of radiotherapy (RT) after radical prostatectomy (RP): Long-term outcomes in the RADICALS-RT trial [NCT00541047]", by C. C. Parker et al.".
Annals of Oncology
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10.1016/j.annonc.2024.05.001.
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Parker, CC;
Clarke, NW;
Cook, AD;
Petersen, PM;
Catton, CN;
Cross, WR;
Kynaston, H;
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(2024)
Randomised Trial of No, Short-term, or Long-term Androgen Deprivation Therapy with Postoperative Radiotherapy After Radical Prostatectomy: Results from the Three-way Comparison of RADICALS-HD (NCT00541047).
European Urology
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Parker, CC;
Petersen, PM;
Cook, AD;
Clarke, NW;
Catton, C;
Cross, WR;
Kynaston, H;
... Sydes, MR; + view all
(2024)
Timing of radiotherapy (RT) after radical prostatectomy (RP): long-term outcomes in the RADICALS-RT trial (NCT00541047).
Annals of Oncology
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Patel, G;
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Advanced Triple-Negative Breast Cancer.
Seminars in Oncology Nursing
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Paton, Nicholas I;
Stöhr, Wolfgang;
Arenas-Pinto, Alejandro;
Clarke, Amanda;
Williams, Ian;
Johnson, Margaret;
Orkin, Chloe;
... Protease Inhibitor monotherapy Versus Ongoing Triple therapy, (PIVOT) Trial Team; + view all
(2024)
Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT).
EClinicalMedicine
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Pavlou, Menelaos;
Ambler, Gareth;
Qu, Chen;
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White, Ian R;
Omar, Rumana Z;
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An evaluation of sample size requirements for developing risk prediction models with binary outcomes.
BMC Medical Research Methodology
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Petrucci, Giovanna;
Hatem, Duaa;
Langley, Ruth;
Cleary, Siobhan;
Gentry-Maharaj, Aleksandra;
Pitocco, Dario;
Rizzi, Alessandro;
... Rocca, Bianca; + view all
(2024)
Effect of very long-term storage and multiple freeze and thaw cycles on 11-dehydro-thromboxane-B2 and 8-iso-prostaglandin F2α, levels in human urine samples by validated enzyme immunoassays.
Scientific Reports
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Pham, Tra My;
Pandis, Nikolaos;
White, Ian R;
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Missing data: issues, concepts, methods.
Seminars in Orthodontics
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10.1053/j.sodo.2024.01.007.
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Pouwels, Koen;
Eyre, David W;
House, Thomas;
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Matthews, Philippa;
Stoesser, Nicole;
Newton, John N;
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(2024)
Improving the representativeness of UK’s national COVID-19 Infection Survey through spatio-temporal regression and post-stratification.
Nature Communications
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Pritchard, Emma;
Vihta, Karina;
Eyre, David W;
Hopkins, Susan;
Peto, Tim EA;
Matthews, Philippa;
Stoesser, Nicole;
... COVID-19 Infection Survey Team; + view all
(2024)
Detecting changes in population trends in infection surveillance using community SARS-CoV-2 prevalence as an exemplar.
American Journal of Epidemiology
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10.1093/aje/kwae091.
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Raimondi, A;
Kim, YW;
Kang, WK;
Langley, RE;
Choi, YY;
Kim, KM;
Nankivell, MG;
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(2024)
Prognostic and predictive impact of sex in locally advanced microsatellite instability high gastric or gastroesophageal junction cancer: An individual patient data pooled analysis of randomized clinical trials.
European Journal of Cancer
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Read, Daniel S;
Gweon, H Soon;
Bowes, Michael J;
Anjum, Muna F;
Crook, Derrick;
Chau, Kevin;
Shaw, Liam P;
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(2024)
Dissemination and Persistence of Antimicrobial Resistance (AMR) along the Wastewater-River Continuum.
Water Research
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Riitho, Victor;
Connon, Roisin;
Gwela, Agnes;
Namusanje, Joseph;
Nhema, Ruth;
Siika, Abraham;
Bwakura-Dangarembizi, Mutsa;
... REALITY Trial Team, .; + view all
(2024)
Biomarkers of mortality in adults and adolescents with advanced HIV in sub-Saharan Africa.
Nature Communications
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Rodger, G;
Chau, K;
Aranega-Bou, P;
Roohi, A;
Moore, G;
Hopkins, KL;
Hopkins, S;
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A workflow for the detection of antibiotic residues, measurement of water chemistry and preservation of hospital sink drain samples for metagenomic sequencing.
Journal of Hospital Infection
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10.1016/j.jhin.2023.11.021.
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Rodriguez-Ruiz, Juan Pablo;
Xavier, Basil Britto;
Stöhr, Wolfgang;
van Heirstraeten, Liesbet;
Lammens, Christine;
Finn, Adam;
Goossens, Herman;
... PERUKI, GAPRUKI and CAP-IT networks; + view all
(2024)
High-resolution genomics identifies pneumococcal diversity and persistence of vaccine types in children with community-acquired pneumonia in the UK and Ireland.
BMC Microbiology
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Roope, Laurence SJ;
Morrell, Liz;
Buchanan, James;
Ledda, Alice;
Adler, Amanda I;
Jit, Mark;
Walker, A Sarah;
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(2024)
Overcoming challenges in the economic evaluation of interventions to optimise antibiotic use.
Communications Medicine
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Russell, Neal;
Clements, Michelle N;
Azmery, Kazi S;
Bekker, Adrie;
Bielicki, Julia;
Dramowski, Angela;
Ellis, Sally;
... Sharland, Michael; + view all
(2024)
Safety and efficacy of whole-body chlorhexidine gluconate
cleansing with or without emollient in hospitalised neonates
(NeoCHG): a multicentre, randomised, open-label, factorial
pilot trial.
EClinicalMedicine
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Samuel, Robert J;
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Understanding the molecular biology of anal squamous cell carcinoma.
International Journal of Cancer
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10.1002/ijc.34782.
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Saner, Flurina AM;
Takahashi, Kazuaki;
Budden, Timothy;
Pandey, Ahwan;
Ariyaratne, Dinuka;
Zwimpfer, Tibor A;
Meagher, Nicola S;
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(2024)
Concurrent RB1 Loss and BRCA-Deficiency Predicts Enhanced Immunological Response and Long-Term Survival in Tubo-Ovarian High-Grade Serous Carcinoma.
Clinical Cancer Research
10.1158/1078-0432.CCR-23-3552.
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Schomaker, Michael;
Denti, Paolo;
Bienczak, Andrzej;
Burger, David;
Diaz, Ivan;
Gibb, Diana;
Walker, Ann;
(2024)
Determining Targets for Antiretroviral Drug Concentrations: a Causal Framework Illustrated with Pediatric Efavirenz Data from the CHAPAS-3 Trial.
Pharmacoepidemiology and Drug Safety
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Scott, Karen;
Chappell, Elizabeth;
Mostafa, Aya;
Volokha, Alla;
Najmi, Nida;
Ebeid, Fatma;
Posokhova, Svitlana;
... Collins, Intira Jeannie; + view all
(2024)
Acceptability of hepatitis C screening and treatment during pregnancy in pregnant women in Egypt, Pakistan, and Ukraine: A cross-sectional survey.
Clinical Liver Disease
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Sen, Arjune;
Toniolo, Sofia;
Tai, Xin You;
Akinola, Mary;
Symmonds, Mkael;
Mura, Sergio;
Galloway, Joanne;
... Husain, Masud; + view all
(2024)
Safety, tolerability, and efficacy outcomes of the Investigation of Levetiracetam in Alzheimer's disease (ILiAD) study: a pilot, double-blind placebo-controlled crossover trial.
Epilepsia Open
10.1002/epi4.13070.
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Sewell, Janey;
Witzel, Charlie;
Dunn, David;
Lampe, Fiona;
Burns, Fiona;
Weatherburn, Peter;
McCormack, Sheena;
... Rodger, Alison; + view all
(2024)
Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT.
Programme Grants for Applied Research
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10.3310/ayhe4598.
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Shaw, Emily S;
Stoker, Neil G;
Potter, Jessica L;
Claassen, Helgard;
Leslie, Alasdair;
Tweed, Conor;
Chiang, Chen-Yuan;
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(2024)
Bedaquiline: what might the future hold?
Lancet Microbe
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Sideris, Michail;
Menon, Usha;
Manchanda, Ranjit;
(2024)
Screening and prevention of ovarian cancer.
Medical Journal of Australia
10.5694/mja2.52227.
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Siepe, Björn S;
Bartoš, František;
Morris, Tim P;
Boulesteix, Anne-Laure;
Heck, Daniel W;
Pawel, Samuel;
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Simulation studies for methodological research in psychology: A standardized template for planning, preregistration, and reporting.
Psychological Methods
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Sinclair, H;
Ranji, T;
Gilbert, DC;
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Will Immune Checkpoint Inhibitors Allow the Non-operative Management of Mismatch Repair-deficient Colorectal Cancer to Become a Standard of Care?
Clinical Oncology
10.1016/j.clon.2024.01.006.
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South, A;
Snowdon, C;
Burnett, E;
Bierer, BE;
Gillies, K;
Isaacs, T;
Sydes, MR;
(2024)
The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff.
Trials
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South, Annabelle;
Bailey, Julia V;
Parmar, Mahesh KB;
Vale, Claire L;
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The effectiveness of interventions to disseminate the results of non-commercial randomised clinical trials to healthcare professionals: a systematic review.
Implementation Science
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STARSurg Collaborative;
the EuroSurg Collaborative;
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Impact of postoperative cardiovascular complications on 30-day mortality after major abdominal surgery: an international prospective cohort study.
Anaesthesia
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Aiken, Z;
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Lipworth, S;
Quan, TP;
Mathers, AJ;
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(2024)
Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics of blaKPC-carbapenemase-producing Enterobacterales in a hospital setting.
JAC-Antimicrobial Resistance
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Sturgeon, Kate;
Judd, Ali;
Burke, Tom;
Foster, Caroline;
Gibb, Diana M;
Le Prevost, Marthe;
Mhizha, Warren;
(2024)
Disseminating the research findings from the adolescents and adults living with Perinatal HIV (AALPHI) study: an approach from young people living with HIV.
Research Involvement and Engagement
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Sullivan, Thomas R;
Morris, Tim P;
Kahan, Brennan C;
Cuthbert, Alana R;
Yelland, Lisa N;
(2024)
Categorisation of continuous covariates for stratified randomisation: How should we adjust?
Statistics in Medicine
10.1002/sim.10060.
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Sydes, Matthew R;
Murray, Macey L;
Ahmed, Saiam;
Apostolidou, Sophia;
Bliss, Judith M;
Bloomfield, Claire;
Cannings-John, Rebecca;
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(2024)
Getting our ducks in a row: The need for data utility comparisons of healthcare systems data for clinical trials.
Contemporary Clinical Trials
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The Cryptic, Consortium;
(2024)
Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach.
Nature Communications
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The ROSSINI-Platform Investigators Collaborating Group;
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ROSSINI-Platform - Reduction of surgical site infection with a platform trial utilising a 'Basket-MAMS' design - Application acceleration award.
NIHR Open Research
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Thomas, Reenu;
Ondongo-Ezhet, Claude;
Motsoaledi, Nini;
Sharland, Mike;
Clements, Michelle;
Velaphi, Sithembiso;
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Incidence, pathogens and antimicrobial resistance of blood and cerebrospinal fluid isolates from a tertiary neonatal unit in South Africa: A 10 year retrospective review.
PloS One
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Tin Tin, Sandar;
Smith‐Byrne, Karl;
Ferrari, Pietro;
Rinaldi, Sabina;
McCullough, Marjorie L;
Teras, Lauren R;
Manjer, Jonas;
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(2024)
Alcohol intake and endogenous sex hormones in women: Meta‐analysis of cohort studies and Mendelian randomization.
Cancer
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Using healthcare systems data for outcomes in clinical trials: issues to consider at the design stage.
Trials
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Turkova, Anna;
Chan, Man K;
Kityo, Cissy;
Kekitiinwa, Adeodata R;
Musoke, Philippa;
Violari, Avy;
Variava, Ebrahim;
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(2024)
D3/Penta 21 clinical trial design: A randomised non-inferiority trial with nested drug licensing substudy to assess dolutegravir and lamivudine fixed dose formulations for the maintenance of virological suppression in children with HIV-1 infection, aged 2 to 15 years.
Contemporary Clinical Trials
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Turner, Rebecca M;
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Determining sample size in a personalized randomized controlled (PRACTical) trial.
Statistics in Medicine
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Tweed, Conor D;
Quartagno, Matteo;
Clements, Michelle N;
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White, Ian R;
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Exploring different objectives in non-inferiority trials.
BMJ
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Twine, Christopher P;
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Lugg-Widger, Fiona V;
Waldron, Cherry-Ann;
Bown, Matt J;
Sydes, Matthew R;
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Challenges of Using Routinely Collected Healthcare System Data in Randomised Trials.
European Journal of Vascular and Endovascular Surgery
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10.1016/j.ejvs.2024.05.010.
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Upton, Ross;
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Bajre, Mamta;
Breen, Maria;
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(2024)
PROTEUS: A Prospective RCT Evaluating Use of AI in Stress Echocardiography.
NEJM AI
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Journal of the Pediatric Infectious Diseases Society
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Subcortical Brain Volumes and Neurocognitive Function in Children With Perinatal HIV Exposure: A Population-Based Cohort Study in South Africa.
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AIDS Care
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Investigating the relationship between thalamic iron concentration and disease severity in secondary progressive multiple sclerosis using quantitative susceptibility mapping: Cross-sectional analysis from the MS-STAT2 randomised controlled trial.
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Improving Specificity for Ovarian Cancer Screening Using a Novel Extracellular Vesicle–Based Blood Test: Performance in a Training and Verification Cohort.
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Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-analyses.
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Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials.
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Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.
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Effect of dolutegravir on folate, vitamin B12 and mean corpuscular volume levels among children and adolescents with HIV: a sub‐study of the ODYSSEY randomized controlled trial.
Journal of the International AIDS Society
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Pharmacokinetic Data of Dolutegravir in Second-line Treatment of Children With Human Immunodeficiency Virus: Results From the CHAPAS4 Trial.
Clinical Infectious Diseases
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Re-examining advice to complete antibiotic courses: a qualitative study with clinicians and patients.
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Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance.
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Tropical Medicine & International Health
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The effect of combination prevention strategies on HIV incidence among gay and bisexual men who have sex with men in the UK: a model-based analysis.
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Impact of the COVID-19 pandemic on antimicrobial stewardship support for general practices in England: a qualitative interview study.
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Evolution of CD4 T-Cell count with age in a cohort of young people growing up with perinatally acquired HIV.
Clinical Infectious Diseases
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Inadequate Lopinavir Concentrations With Modified 8-hourly Lopinavir/Ritonavir 4:1 Dosing During Rifampicin-based Tuberculosis Treatment in Children Living With HIV.
The Pediatric Infectious Disease Journal (PIDJ)
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Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents.
Clinical Pharmacokinetics
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High-resolution characterisation of short-term temporal variability in the taxonomic and resistome composition of wastewater influent.
Microbial Genomics
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Percutaneous Revascularization for Ischemic Left Ventricular Dysfunction: Cost-Effectiveness Analysis of the REVIVED-BCIS2 Trial.
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Facilities for optimizing and designing multiarm multistage (MAMS) randomized controlled trials with binary outcomes.
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Statistics in Medicine
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Benefit From Fractionated Dose-Dense Chemotherapy in Patients With Poor Prognostic Ovarian Cancer: ICON-8 Trial.
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Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial.
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'Nothing about us without us': multi-country adolescent patient-led recruitment information in the long-acting treatment in adolescents (LATA) trial - an animated video to compliment 'traditional' participant information.
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Medical Mycology
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Type 2 Diabetes Mellitus and Efficacy Outcomes from Immune Checkpoint Blockade in Patients with Cancer.
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Polymorphisms in Cyclooxygenase, Lipoxygenase and TP53 genes predict colorectal polyp risk reduction by aspirin in the seAFOod polyp prevention trial.
Cancer Prevention Research
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Efficacy and moderators of efficacy of cognitive behavioural therapies with a trauma focus in children and adolescents: an individual participant data meta-analysis of randomised trials.
The Lancet Child and Adolescent Health
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Comparative study showed that children faced a 78% higher risk of new-onset conditions after they had COVID-19.
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Penicillin Binding Protein Substitutions Co-occur with Fluoroquinolone Resistance in ‘Epidemic’ Lineages of Multi Drug-Resistant Clostridioides difficile.
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COVID-19 and MIS-C treatment in children—results from an international survey.
European Journal of Pediatrics
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Colorectal polyp outcomes after participation in the seAFOod polyp prevention trial: Evidence of rebound elevated colorectal polyp risk after short-term aspirin use.
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Standards for clinical trials for treating TB.
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Electronic health records to capture primary outcome measures: two case studies in HIV prevention research.
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Interpretation of active-control randomised trials: the case for a new analytical perspective involving averted events.
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Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery.
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BMC Medicine
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Individual Participant Data Network Meta-Analysis of Neoadjuvant Chemotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Junction Carcinoma.
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Booster Vaccination Against SARS-CoV-2 Induces Potent Immune Responses in People With Human Immunodeficiency Virus.
Clinical Infectious Diseases
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The National COVID Cancer Antibody Survey: a hyper-accelerated study proof of principle for cancer research.
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Efficacy of ultra-short, response-guided sofosbuvir and daclatasvir therapy for hepatitis C in a single-arm mechanistic pilot study.
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Rise in alanine aminotransferase after HCV treatment is a highly sensitive screen for treatment failure.
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Behavioural intervention to reduce sexually transmitted infections in people aged 16–24 years in the UK: the safetxt RCT.
Public Health Research
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The hard part we often forget: providing care to children and adolescents with advanced HIV disease.
Journal of the International AIDS Society
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Fu, Zhuxuan;
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Lifetime ovulatory years and risk of epithelial ovarian cancer: a multinational pooled analysis.
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Plasma and rectal mucosal oxylipin levels during aspirin and eicosapentaenoic acid treatment in the seAFOod polyp prevention trial.
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Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis.
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Galante, Julieta;
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Individual participant data systematic review and meta-analysis of randomised controlled trials assessing adult mindfulness-based programmes for mental health promotion in non-clinical settings.
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Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis.
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Predictors of the experience of a Cytosponge test: analysis of patient survey data from the BEST3 trial.
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Co-trimoxazole prophylaxis for children who are HIV-exposed and uninfected: a systematic review.
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European Journal of Preventive Cardiology
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A Repurposing Programme Evaluating Repurposing Transdermal Oestradiol Patches for the Treatment of Prostate Cancer Within the PATCH and STAMPEDE Trials: Current Results and Adapting Trial Design.
Clinical Oncology
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Management of patients with advanced prostate cancer—metastatic and/or castration-resistant prostate cancer: report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022.
European Journal of Cancer
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Pre-operative prognostic factors for 5-year survival following pulmonary metastasectomy from colorectal cancer. A systematic review and meta-analysis.
European Journal of Cardio-Thoracic Surgery
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Godolphin, Peter;
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Outcome adjudication in randomised trials in leading medical journals: Protocol for a methodological review.
OSF Preprints: Charlottesville, VA, USA.
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Marlin, Nadine;
Cornett, Chantelle;
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Use of multiple covariates in assessing treatment-effect modifiers: A methodological review of individual participant data meta-analyses.
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Re: 'Evaluating the use of ¹⁸F-FDG PET/CT in the workup of Staphylococcus aureus bacteraemia: a cost-utility analysis' by Ong et al.
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Advanced Imaging for Detection of Foci of Infection in Staphylococcus aureus Bacteremia- Can a Scan Save Lives?
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Using re-randomisation designs to increase the efficiency and applicability of retention studies within trials: a case study.
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(2023)
Involving patients and the public In sTatistIcal Analysis pLans (INITIAL): A delphi survey.
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Enhancing involvement of people with multiple sclerosis in clinical trial design.
Multiple Sclerosis Journal
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Grosser, B;
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Stroma AReactive Invasion Front Areas (SARIFA) improves prognostic risk stratification of perioperative chemotherapy treated oesophagogastric cancer patients from the MAGIC and the ST03 trial.
British Journal of Cancer
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Key Components of Antenatal Lifestyle Interventions to Optimize Gestational Weight Gain: Secondary Analysis of a Systematic Review.
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Harrison, Rebecca E;
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Cycle Threshold Values as Indication of Increasing SARS-CoV-2 New Variants, England, 2020–2022.
Emerging Infectious Diseases
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“Sex without fear”: exploring the psychosocial impact of oral HIV pre-exposure prophylaxis on gay men in England.
AIDS Research and Therapy
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Heinze, Georg;
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Phases of methodological research in biostatistics—Building the evidence base for new methods.
Biometrical Journal
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Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening tria.
International Journal of Cancer
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Guideline adherence and survival of patients with candidaemia in Europe: results from the ECMM Candida III multinational European observational cohort study.
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Evidence-based antenatal interventions to reduce the incidence of small vulnerable newborns and their associated poor outcomes.
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(2023)
Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial.
The Lancet
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Hsieh, Shao-Fan;
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Lack of transparent reporting of trial monitoring approaches in randomised controlled trials: A systematic review of contemporary protocol papers.
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QT prolongation in patients treated for drug-resistant tuberculosis.
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Ellenberg, Susan S;
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Monitoring Multiple U.S. Government–Supported Covid-19 Vaccine Trials.
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Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility.
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Systematic reviews and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: mortality, morbidity, and organ failure.
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Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19.
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British Journal of Cancer
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Consensus Statement for Protocols of Factorial Randomized Trials Extension of the SPIRIT 2013 Statement.
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Bone mineral density among children living with HIV failing first-line anti-retroviral therapy in Uganda: A sub-study of the CHAPAS-4 trial.
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Care after premenopausal risk-reducing salpingo-oophorectomy in high-risk women: Scoping review and international consensus recommendations.
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The Smooth Away From Expected (SAFE) non-inferiority frontier: theory and implementation with an application to the D3 trial.
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A comparison of different population-level summary measures for randomised trials with time-to-event outcomes, with a focus on non-inferiority trials.
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Optimal maintenance strategy following FOLFOX plus anti-EGFR induction therapy in patients with RAS wild type metastatic colorectal cancer: An individual patient data pooled analysis of randomised clinical trials.
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Investigation of Causal Effects of Protein Biomarkers on Cardiovascular Disease in Persons with HIV.
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Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort study (NeoOBS).
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An observer-blinded, cluster randomised trial of a typhoid conjugate vaccine in an urban South Indian cohort.
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Peripheral Neuropathy in Virologically Suppressed People Living with HIV: Evidence from the PIVOT Trial.
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Defining Peri-Operative Myocardial Injury during Cardiac Surgery Using High-Sensitivity Troponin T.
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International Validation of the EORTC QLQ-ANL27, a Field Study to Test the Anal Cancer-Specific Health-Related Quality-of-Life Questionnaire.
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Patients’ priorities around drug-resistant tuberculosis treatment: A multi-national qualitative study from Mongolia, South Africa and Georgia.
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A population-scale temporal case-control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP).
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Regional Histopathology and Prostate MRI Positivity: A Secondary Analysis of the PROMIS Trial.
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The effect of aspirin and eicosapentaenoic acid on urinary biomarkers of prostaglandin E2 synthesis and platelet activation in participants of the seAFOod polyp prevention trial.
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A comparison of covariate adjustment approaches under model misspecification in individually randomized trials.
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Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial.
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Practical approaches to Bayesian sample size determination in non-inferiority trials with binary outcomes.
Statistics in Medicine
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Uddin, Masuma;
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Evaluating whether the proportional odds models to analyse ordinal outcomes in COVID-19 clinical trials is providing clinically interpretable treatment effects: A systematic review.
Clinical Trials
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Which patients with metastatic hormone-sensitive prostate cancer benefit from docetaxel: a systematic review and meta-analysis of individual participant data from randomised trials.
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Quality indicators for appropriate antibiotic prescribing in urinary tract infections in children.
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Omicron-Associated Changes in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Symptoms in the United Kingdom.
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First Pharmacokinetic Data of Tenofovir Alafenamide Fumarate and Tenofovir With Dolutegravir or Boosted Protease Inhibitors in African Children: A Substudy of the CHAPAS-4 Trial.
Clinical Infectious Diseases
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Implementing hierarchical network meta-analysis incorporating exchangeable dose effects compared to standard hierarchical network meta-analysis.
BMJ Evidence-Based Medicine
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Protection against SARS-CoV-2 Omicron BA.4/5 variant following booster vaccination or breakthrough infection in the UK.
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A DELPHI study priority setting the remaining challenges for the use of routinely collected data in trials: COMORANT-UK.
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Relationship between 233 colorectal cancer risk loci and survival in 1926 patients with advanced disease.
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Understanding experiences of potential harm among MSM (cis and trans) using HIV self-testing in the SELPHI randomised controlled trial in England and Wales: a mixed-methods study.
Sexually Transmitted Infections
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PROTEUS Study: A Prospective Randomised Controlled Trial Evaluating the Use of Artificial Intelligence in Stress Echocardiography.
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Long term pregnancy outcomes of women with cancer following fertility preservation: A systematic review and meta-analysis.
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A likelihood ratio approach for utilizing case-control data in the clinical classification of rare sequence variants: Application to BRCA1 and BRCA2.
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Spontaneous Clearance Of Vertically Acquired Hepatitis C Infection: Implications For Testing And Treatment.
Clinical Infectious Diseases
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Clinical Infectious Diseases
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Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
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Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomised ODYSSEY trial.
The Lancet HIV
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Learning and memory function in young people with and without perinatal HIV in England.
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Perceptions and Practicalities Influencing Pre-exposure Prophylaxis Adherence Among Men Who Have Sex with Men in England.
AIDS and Behavior
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American Journal of Epidemiology
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International Journal of Stroke
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British Journal of Cancer
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Core Outcome Measures for Perioperative and Anaesthetic Care (COMPAC): a modified Delphi process to develop a core outcome set for trials in perioperative care and anaesthesia.
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Demographics and Outcomes of Initial Phase of COVID-19 Medicines Delivery Units Across 4 UK Centers During Peak B1.1.529 Omicron Epidemic: A Service Evaluation.
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Adjuvant Chemotherapy for Muscle-invasive Bladder Cancer: A Systematic Review and Meta-analysis of Individual Participant Data from Randomised Controlled Trials.
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Systematic review of wastewater surveillance of antimicrobial resistance in human populations.
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The 2nd European Carotid Surgery Trial (ECST-2): rationale and protocol for a randomised clinical trial comparing immediate revascularisation versus optimised medical therapy alone in patients with symptomatic and asymptomatic carotid stenosis at low to intermediate risk of stroke.
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Examining oral pre-exposure prophylaxis (PrEP) literacy among participants in an HIV vaccine trial preparedness cohort study.
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Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal cancer treatment (ICON8): overall survival results from an open-label, randomised, controlled, phase 3 trial.
The Lancet Oncology
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Cost-utility analysis of adding abiraterone acetate plus prednisone/prednisolone to long-term hormone therapy in newly diagnosed advanced prostate cancer in England: Lifetime decision model based on STAMPEDE trial data.
PLoS One
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Coenzyme Q10 to manage chronic heart failure with a reduced ejection fraction: a systematic review and economic evaluation.
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BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age.
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Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance mechanisms.
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Epidemiological cutoff values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis.
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Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk.
European Journal of Human Genetics
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Polygenic risk modeling for prediction of epithelial ovarian cancer risk.
European Journal of Human Genetics
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Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci.
JNCI: Journal of the National Cancer Institute
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Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study.
British Journal of Sports Medicine
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American Journal of Respiratory and Critical Care Medicine
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Systematic review and meta-analysis of intravenous iron therapy for adults with non-anaemic iron deficiency: An abridged Cochrane review.
Journal of Cachexia, Sarcopenia and Muscle
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The Indian Journal of Medical Research
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Effects of regional citrate anticoagulation on thrombin generation, fibrinolysis and platelet function in critically ill patients receiving continuous renal replacement therapy for acute kidney injury: a prospective study.
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Adopt to adapt: Efforts to Keep the RAMPART Trial of Adjuvant Immunotherapy in Renal Cancer on Track in the COVID-19 Era.
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Whole blood versus red cell concentrates for children with severe anaemia: a secondary analysis of the Transfusion and Treatment of African Children (TRACT) trial.
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Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022.
European Urology
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High-dose Radiotherapy or Androgen Deprivation Therapy (HEAT) as Treatment Intensification for Localized Prostate Cancer: An Individual Patient–data Network Meta-analysis from the MARCAP Consortium.
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Diagnostic pathways for breast cancer in 10 International Cancer Benchmarking Partnership (ICBP) jurisdictions: An international comparative cohort study based on questionnaire and registry data.
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Dolutegravir dosing for children with HIV weighing less than 20 kg: pharmacokinetic and safety substudies nested in the open-label, multicentre, randomised, non-inferiority ODYSSEY trial.
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Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: a systematic review and meta-analysis.
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Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study.
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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease.
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A genomic epidemiological study shows that prevalence of antimicrobial resistance in Enterobacterales is associated with the livestock host, as well as antimicrobial usage.
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Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial.
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No need for secondary Pneumocystis jirovecii pneumonia prophylaxis in adult people living with HIV from Europe on ART with suppressed viraemia and a CD4 cell count greater than 100 cells/µL.
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Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol.
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Defeating Paediatric Tuberculous Meningitis: Applying the WHO "Defeating Meningitis by 2030: Global Roadmap".
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Do variations in primary care practice characteristics explain the effect of a financial incentive scheme on antibiotic prescribing? A longitudinal study of the Quality Premium intervention in NHS England.
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Genital secretion HIV RNA shedding in HIV-positive patients on ritonavir-boosted protease inhibitor monotherapy or standard combination ART: a cross-sectional sub-study from the PIVOT Trial.
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Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03).
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Withholding primary PcP prophylaxis in virologically suppressed HIV patients: An emulation of a pragmatic trial in COHERE.
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European Journal of Neurology
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Weekly platinum-based chemotherapy versus 3-weekly platinum-based chemotherapy for newly diagnosed ovarian cancer (ICON8): quality-of-life results of a phase 3, randomised, controlled trial.
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A lifecourse perspective on childhood hearing loss: prevalence, risk factors, and outcomes.
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Evaluation, Validation, and Recognition of the Point-of-Care Circulating Cathodic Antigen, Urine-Based Assay for Mapping Schistosoma mansoni Infections.
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Circulating Anodic Antigen (CAA): A Highly Sensitive Diagnostic Biomarker to Detect Active Schistosoma Infections-Improvement and Use during SCORE.
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Routine Antenatal Anti-D Prophylaxis in Women Who Are Rh(D) Negative: Meta-Analyses Adjusted for Differences in Study Design and Quality.
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Vale, CL;
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Involvement of consumers in studies run by the Medical Research Council Clinical Trials Unit: results of a survey.
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von Knorring, N;
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Quality Control and Performance of HIV Rapid Tests in a Microbicide Clinical Trial in Rural KwaZulu-Natal.
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Characterisation of Clostridium difficile hospital ward-based transmission using extensive epidemiological data and molecular typing.
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Young, J;
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2011
Amankwah, EK;
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Polymorphisms in Stromal Genes and Susceptibility to Serous Epithelial Ovarian Cancer: A Report from the Ovarian Cancer Association Consortium.
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Askie, LM;
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NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol.
BMC Pediatrics
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Beesley, J;
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Functional Polymorphisms in the TERT Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers.
PLOS ONE
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Brueton, V;
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Complexities of retention in primary care randomised trials: a thematic analysis of in-depth interviews.
Trials
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Brueton, V;
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Strategies to reduce attrition in randomised trials.
Trials
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Burnell, M;
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Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials.
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Candy, B;
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Laxatives or methylnaltrexone for the management of constipation in palliative care patients.
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Cozzi-Lepri, A;
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Can linear regression modeling help clinicians in the interpretation of genotypic resistance data? An application to derive a lopinavir-score.
PLOS One
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Davey, J;
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Characteristics of meta-analyses and their component studies in the Cochrane Database of Systematic Reviews: a cross-sectional, descriptive analysis.
BMC Medical Research Methodology
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Dingle, KE;
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Clinical Clostridium difficile: clonality and pathogenicity locus diversity.
PLoS One
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Finney, JM;
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An efficient record linkage scheme using graphical analysis for identifier error detection.
BMC Medical Informatics and Decision Making
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Gafos, M;
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“One Teabag Is Better than Four”: Participants Response to the Discontinuation of 2% PRO2000/5 Microbicide Gel in KwaZulu-Natal, South Africa.
PLoS ONE
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Haberer, JE;
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Excellent Adherence to Antiretrovirals in HIV plus Zambian Children Is Compromised by Disrupted Routine, HIV Nondisclosure, and Paradoxical Income Effects.
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Results of Antiretroviral Treatment Interruption and Intensification in Advanced Multi-Drug Resistant HIV Infection from the OPTIMA Trial.
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Lurie, G;
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Estrogen Receptor Beta rs1271572 Polymorphism and Invasive Ovarian Carcinoma Risk: Pooled Analysis within the Ovarian Cancer Association Consortium.
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Nankivell, M;
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Releasing interim results from a randomised clinical trial: an example from the QUARTZ trial.
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Phillips, PP;
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The evolution of and challenges in defining the clinical endpoint in tuberculosis treatment trials with non-inferiority designs.
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Royston, P;
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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit.
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Sen, EF;
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Assessment of pediatric asthma drug use in three European countries; a TEDDY study.
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A randomised controlled trial of ion-exchange water softeners for the treatment of eczema in children.
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Timms, JF;
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Early Detection of Ovarian Cancer in Samples Pre-Diagnosis Using CA125 and MALDI-MS Peaks.
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Wilks, DC;
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Dietary energy density and adiposity: Employing bias adjustments in a meta-analysis of prospective studies.
BMC Public Health
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Wilks, DC;
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Objectively Measured Physical Activity and Fat Mass in Children: A Bias-Adjusted Meta-Analysis of Prospective Studies.
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Causes of Acute Hospitalization in Adolescence: Burden and Spectrum of HIV-Related Morbidity in a Country with an Early-Onset and Severe HIV Epidemic: A Prospective Survey.
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Johnatty, SE;
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Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility "Hot-Spot''.
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McGregor, AH;
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Function after spinal treatment, exercise and rehabilitation (FASTER): improving the functional outcome of spinal surgery.
BMC Musculoskeletal Disorders
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Nicolaides, AN;
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Novel one-stop multidisciplinary follow-up clinic significantly improves cancer risk management in BRCA1/2 carriers.
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A mixed methods and triangulation model for increasing the accuracy of adherence and sexual behaviour data: the Microbicides Development Programme.
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Assessing the accuracy of adherence and sexual behaviour data in the MDP301 vaginal microbicides trial using a mixed methods and triangulation model.
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Reappraising the concept of massive transfusion in trauma.
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The Management of Staphylococcus aureus Bacteremia in the United Kingdom and Vietnam: A Multi-Centre Evaluation.
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Pretreatment CD4 Cell Slope and Progression to AIDS or Death in HIV-Infected Patients Initiating Antiretroviral Therapy-The CASCADE Collaboration: A Collaboration of 23 Cohort Studies.
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Young people in the United Kingdom and Ireland with perinatally acquired HIV: The pediatric legacy for adult services.
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Nunn, A;
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Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial.
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An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer.
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2008
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The Long-Term Effects of a Peer-Led Sex Education Programme (RIPPLE): A Cluster Randomised Trial in Schools in England.
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Are there better methods of monitoring MRSA control than bacteraemia surveillance? An observational database study.
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Epigenotyping in Peripheral Blood Cell DNA and Breast Cancer Risk: A Proof of Principle Study.
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