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The association of abdominal muscle with outcomes after scheduled abdominal aortic aneurysm repair

Shah, N; Abeysundara, L; Dutta, P; Christodoulidou, M; Wylie, S; Richards, T; Schofield, N; (2017) The association of abdominal muscle with outcomes after scheduled abdominal aortic aneurysm repair. Anaesthesia , 72 (9) pp. 1107-1111. 10.1111/anae.13980. Green open access

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Abstract

Sarcopenia is the degenerative loss of core muscle mass. It is an aspect of frailty, which is associated with increased rates of peri‐operative harm. We assessed the association of the cross‐sectional areas of abdominal muscles, including psoas, with survival during a median (IQR [range]) follow‐up of 3.8 (3.2–4.4 [0.0–5.1]) years after scheduled endovascular (132) or open (5) abdominal aortic aneurysm repair in 137 patients. In multivariate analysis, mortality hazard (95%CI) was independently associated with: age, 1.06 (1.01–1.13) per year, p = 0.03; and the adjusted area of the left psoas muscle, 0.94 (0.81–1.01) per mm2.kg−0.83, p = 0.08. Shortened hospital stay was independently associated with haemoglobin concentration and adjusted left psoas muscle area, hazard ratio (95%) 1.01 (1.00–1.02) per g.l−1 and 1.05 (1.02–1.07) per mm2.kg−0.83, p = 0.04 and 0.001, respectively.

Type: Article
Title: The association of abdominal muscle with outcomes after scheduled abdominal aortic aneurysm repair
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/anae.13980
Publisher version: http://dx.doi.org/10.1111/anae.13980
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Anesthesiology, aneurysm, aortic, frailty, sarcopenia, LIVER-TRANSPLANTATION, SARCOPENIC OBESITY, PROGNOSTIC-FACTOR, MASS INDEX, COMPLICATIONS, PREDICTION, MORTALITY, SURVIVAL, EXERCISE, SURGERY
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10046888
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