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High Rate of HIV Re-suppression After Viral Failure on First Line Antiretroviral Therapy in the Absence of Switch to Second Line.

Gupta, RK; Goodall, RL; Ranopa, M; Kityo, C; Munderi, P; Lyagoba, F; Mugarura, L; ... DART Virology Group and Trial Team; + view all (2014) High Rate of HIV Re-suppression After Viral Failure on First Line Antiretroviral Therapy in the Absence of Switch to Second Line. Clin Infect Dis , 58 (7) pp. 1023-1026. 10.1093/cid/cit933. Green open access

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Abstract

In a randomised comparison of nevirapine or abacavir with zidovudine + lamivudine, routine viral load monitoring was not performed yet 27% of individuals with viral failure at w48 re-suppressed by w96 without switching. This supports WHO recommendations that suspected viral failure should trigger adherence counselling and repeat measurement before considering treatment switch.

Type: Article
Title: High Rate of HIV Re-suppression After Viral Failure on First Line Antiretroviral Therapy in the Absence of Switch to Second Line.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/cid/cit933
Publisher version: http://dx.doi.org/10.1093/cid/cit933
Additional information: © The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/1423480
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