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Syphilis, hepatitis C and HIV in Eastern Europe

Bailey, H; Turkova, A; Thorne, C; (2017) Syphilis, hepatitis C and HIV in Eastern Europe. Current Opinion in Infectious Diseases , 30 (1) pp. 93-100. 10.1097/QCO.0000000000000326. Green open access

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Abstract

PURPOSE OF REVIEW: Eastern Europe and Central Asia (EECA) has experienced large-scale epidemics of syphilis, hepatitis C virus (HCV) and HIV over the past few decades. Here, we review recent evidence on the epidemiology of and the response to these intersecting epidemics. RECENT FINDINGS: The HIV epidemic in EECA continues to expand, with new infections increasing by more than 50% between 2010 and 2015. HCV is now in the top 10 causes of death in EECA, with Russia accounting for more than half of the global burden of HCV infections, but access to direct-acting antivirals remains a major obstacle for control of the epidemic. Although syphilis incidence is generally declining, high prevalence is reported in key populations, particularly sex workers and people who inject drugs. Recent epidemiological studies have highlighted very high prevalence of HIV, syphilis and HCV in prison populations, alongside poor access to prevention and treatment. SUMMARY: Multiple factors are contributing to the ongoing and overlapping HIV, HCV and syphilis epidemics in EECA, including low coverage with antiretroviral therapy and insufficient scale of prevention services. Further research is required to estimate the burden of infections and identify effective prevention and treatment strategies in hard-to-reach key populations, particularly men who have sex with men.

Type: Article
Title: Syphilis, hepatitis C and HIV in Eastern Europe
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/QCO.0000000000000326
Publisher version: http://dx.doi.org/10.1097/QCO.0000000000000326
Language: English
Additional information: Copyright © 2017 Wolters Kluwer Health, Inc. This is the accepted manuscript version of this article published in Current Opinion in Infectious Diseases; the final published version of record can be found at http://dx.doi.org/10.1097/QCO.0000000000000326.
Keywords: Science & Technology, Life Sciences & Biomedicine, Infectious Diseases, Eastern Europe, Epidemiology, Hepatitis C Virus, HIV, Syphilis, Female Sex Workers, Be Released Prisoners, Inject Drugs, Macrolide Resistance, Russian-Federation, Treponema-Pallidum, Global Burden, Central-Asia, Viral-Hepatitis, People
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1524608
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