Kahan, BC;
Jairath, V;
Doré, CJ;
Morris, TP;
(2014)
The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies.
Trials
, 15
, Article 139. 10.1186/1745-6215-15-139.
![[thumbnail of 1745-6215-15-139.pdf]](https://discovery.ucl.ac.uk/style/images/fileicons/application_pdf.png) Preview |
PDF
1745-6215-15-139.pdf Available under License : See the attached licence file. Download (326kB) |
|
PDF (Additional file 1: Study information, simulation details and results)
1745-6215-15-139-s1.docx Available under License : See the attached licence file. Download (43kB) |
Abstract
Adjustment for prognostic covariates can lead to increased power in the analysis of randomized trials. However, adjusted analyses are not often performed in practice.
| Type: | Article |
|---|---|
| Title: | The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1745-6215-15-139 |
| Publisher version: | http://dx.doi.org/10.1186/1745-6215-15-139 |
| Language: | English |
| Additional information: | © 2014 Kahan et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1428523 |
Downloads since deposit
178Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months
Archive Staff Only
 |
View Item |
