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Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape

Phillips, PPJ; Mitnick, CD; Neaton, JD; Nahid, P; Lienhardt, C; Nunn, AJ; (2019) Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape. PLOS Medicine , 16 (3) , Article e1002767. 10.1371/journal.pmed.1002767. Green open access

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Abstract

In a Collection Review, Patrick Phillips and colleagues discuss developments in clinical trial design for the evaluation of TB therapeutics.

Type: Article
Title: Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pmed.1002767
Publisher version: https://doi.org/10.1371/journal.pmed.1002767
Language: English
Additional information: Copyright: © 2019 World Health Organization. Licensee Public Library of Science. This is an open access article distributed under the Creative Commons Attribution IGO License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (http://creativecommons.org/licenses/by/3.0/igo/). In any use of this article, there should be no suggestion that WHO endorses any specific organization, products or services. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL.
Keywords: Tuberculosis, Extensively drug-resistant tuberculosis, Treatment guidelines, Drug therapy, Clinical trials, Phase III clinical investigation, Multi-drug-resistant tuberculosis, Tuberculosis diagnosis and management
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/10071566
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