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Reporting and analysis of trials using stratified randomisation in leading medical journals: review and reanalysis

Kahan, BC; Morris, TP; (2012) Reporting and analysis of trials using stratified randomisation in leading medical journals: review and reanalysis. BMJ , 345 , Article e5840. 10.1136/bmj.e5840. Green open access

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Abstract

To assess how often stratified randomisation is used, whether analysis adjusted for all balancing variables, and whether the method of randomisation was adequately reported, and to reanalyse a previously reported trial to assess the impact of ignoring balancing factors in the analysis.

Type: Article
Title: Reporting and analysis of trials using stratified randomisation in leading medical journals: review and reanalysis
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/bmj.e5840
Publisher version: http://dx.doi.org/10.1136/bmj.e5840
Language: English
Additional information: © 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License (CC BY-NC 2.0), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode. PMCID: PMC3444136
Keywords: Data interpretation, statistical, documentation, humans, multicenter studies as topic, periodicals as topic, randomized controlled trials as topic
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/1406687
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