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Gynaecological surveillance in high risk women

Dilley, J; Gentry-Maharaj, A; Menon, U; (2016) Gynaecological surveillance in high risk women. Minerva Ginecologica , 68 (5) pp. 497-508. Green open access

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Abstract

Increasing availability of genetic testing and falling costs of the tests suggests that growing numbers of unaffected women will be identified worldwide who are at increased risk of gynaecological malignancies. The challenge in those identified is to prevent and detect the disease early without causing significant harm. Currently surgery remains the cornerstone of management. Most women undergoing surgery do not report a significant deterioration of their physical and mental health-related quality of life (1). However the resulting premature menopause is associated with decrease in sexual functioning and vasomotor symptoms even in women on hormone replacement therapy (HRT)(2)(3). As a result there is a continued effort to develop effective screening strategies for high risk women.

Type: Article
Title: Gynaecological surveillance in high risk women
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.minervamedica.it/en/journals/minerva-gi...
Language: English
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/1482205
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