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Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative.

Bogaerts, J; Sydes, MR; Keat, N; McConnell, A; Benson, A; Ho, A; Roth, A; ... Seymour, M; + view all (2015) Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative. Eur J Cancer , 51 (3) pp. 271-281. 10.1016/j.ejca.2014.10.027. Green open access

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Abstract

The past three decades have seen rapid improvements in the diagnosis and treatment of most cancers and the most important contributor has been research. Progress in rare cancers has been slower, not least because of the challenges of undertaking research.

Type: Article
Title: Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ejca.2014.10.027
Publisher version: http://dx.doi.org/10.1016/j.ejca.2014.10.027
Additional information: © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
Keywords: Bayesian, Clinical trials, Frequentist, Methodology, Multi-arm, Randomised controlled trials, Rare cancers, Humans, International Cooperation, Neoplasms, Public-Private Sector Partnerships, Randomized Controlled Trials as Topic, Rare Diseases, Research Design
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/1460034
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