sheppard, A;
Vaughan, A;
Jones, N;
Turner, P;
Turner, C;
Efstratiou, A;
Patel, D;
... Seale, AC; + view all
(2016)
Capsular typing method for Streptococcus agalactiae using whole genome sequence data.
Journal of Clinical Microbiology
, 54
(5)
pp. 1388-1390.
10.1128/JCM.03142-15.
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Abstract
Group B streptococcus (GBS) capsular serotype is a major determinant of virulence, and affects potential vaccine coverage. Here we report a whole genome sequencing-based method for GBS serotype assignment. This shows high agreement (kappa=0.92) with conventional methods, and increased serotype assignment (100%) to all ten capsular types.
| Type: | Article |
|---|---|
| Title: | Capsular typing method for Streptococcus agalactiae using whole genome sequence data |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1128/JCM.03142-15 |
| Publisher version: | http://dx.doi.org/10.1128/JCM.03142-15 |
| Language: | English |
| Additional information: | Copyright © 2016 Sheppard et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1475474 |
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