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Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007-12, with whole pathogen genome sequences: an observational study.

Walker, TM; Lalor, MK; Broda, A; Saldana Ortega, L; Morgan, M; Parker, L; Churchill, S; ... Conlon, CP; + view all (2014) Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007-12, with whole pathogen genome sequences: an observational study. Lancet Respir Med , 2 (4) 285 - 292. 10.1016/S2213-2600(14)70027-X. Green open access

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Abstract

Patients born outside the UK have contributed to a 20% rise in the UK's tuberculosis incidence since 2000, but their effect on domestic transmission is not known. Here we use whole-genome sequencing to investigate the epidemiology of tuberculosis transmission in an unselected population over 6 years.

Type: Article
Title: Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007-12, with whole pathogen genome sequences: an observational study.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/S2213-2600(14)70027-X
Publisher version: http://dx.doi.org/10.1016/S2213-2600(14)70027-X
Language: English
Additional information: Copyright © Walker et al. Open Access article distributed under the terms of CC BY
Keywords: Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, England, Genome, Bacterial, Humans, Incidence, Infant, Middle Aged, Mycobacterium tuberculosis, Risk Factors, Tuberculosis, Young Adult
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health
URI: https://discovery.ucl.ac.uk/id/eprint/1421157
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