UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Cancer in adolescents and young adults living with HIV

Bohlius, J; Foster, C; Naidu, G; Sengayi, M; Turkova, A; (2018) Cancer in adolescents and young adults living with HIV. Current Opinion in HIV and AIDS , 13 (3) pp. 196-203. 10.1097/COH.0000000000000460. Green open access

[thumbnail of Turkova_Cancer in adolescents and young adults living with HIV_AAM.pdf]
Preview
Text
Turkova_Cancer in adolescents and young adults living with HIV_AAM.pdf - Accepted Version

Download (705kB) | Preview

Abstract

PURPOSE OF REVIEW: Adults living with HIV have an increased risk of malignancy yet there is little data for adolescents and young adults. We reviewed recently published cancer epidemiology, treatment, and outcome data for adolescents and young adults living with HIV (AYALHIV) aged 10 to less than 25 years between 2016 and 2017. RECENT FINDINGS: AYALHIV are at increased risk of developing cancer compared to their uninfected peers. Kaposi sarcoma and non-Hodgkin lymphoma occur most frequently with variation by geographical region. Increased cancer risk is associated with HIV-related immunosuppression and coinfection with oncogenic viruses. Published data, particularly on posttreatment outcomes, remain limited and analyses are hampered by lack of data disaggregation by age and route of HIV transmission. SUMMARY: Although data are sparse, the increased cancer risk for AYALHIV is the cause for concern and must be modified by improving global access and uptake of antiretroviral therapy, human papilloma virus (HPV) and hepatitis B virus (HBV) vaccination, screening for hepatitis B and C infection, and optimized cancer screening programs. Education aimed at reducing traditional modifiable cancer risk factors should be embedded within multidisciplinary services for AYALHIV.

Type: Article
Title: Cancer in adolescents and young adults living with HIV
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/COH.0000000000000460
Publisher version: https://journals.lww.com/co-hivandaids/Fulltext/20...
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: adolescents, cancer, HIV, prevention, young adults
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10053477
Downloads since deposit
79Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item