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The UK register of HIV seroconverters: Methods and analytical issues

Beral, V; Babiker, A; Brettle, RP; Carne, C; Darbyshire, JH; Evans, BG; Gilson, RJC; ... Wellsteed, S; + view all (1996) The UK register of HIV seroconverters: Methods and analytical issues. EPIDEMIOL INFECT , 117 (2) 305 - 312. 10.1017/S0950268800001485. Green open access

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Abstract

A Register of HIV-infected persons who have had a negative antibody test within 3 years of their first antibody positive test (seroconverters) is being set up in the UK to monitor the distribution of times from HIV seroconversion to AIDS (the incubation period) and to death. It will also provide a national resource for use by those designing studies in this group of individuals. Clinicians caring for HIV-positive persons in Genito-Urinary Medicine, Infectious Disease and other departments throughout the UK were asked to participate by providing information on eligible subjects. Most laboratories undertaking HIV antibody testing were also contacted and asked to provide the name of the attending clinician for all seroconverters identified through the HIV laboratory reporting systems of the PHLS Communicable Disease Surveillance Centre (CDSC) and the Scottish Centre for Infection and Environmental Health (SCIEH) and for any other seroconverters known to them but not identified by CDSC or SCIEH. Data items sought for the Register include: sex, ethnic group, probable route of HIV transmission, annual CD4 counts, details of therapy and prophylaxis prescribed, AIDS-defining events and vital status. Follow up information is collected annually. Wherever possible, all seroconverters known to a clinic have been identified, whether currently alive or dead, either from clinic records or laboratory reporting or both. The objective is to establish and update a complete register of seroconverters on a long-term basis to provide reliable estimates of the incubation period on which future projections of AIDS cases in the UK can be made.

Type: Article
Title: The UK register of HIV seroconverters: Methods and analytical issues
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S0950268800001485
Publisher version: http://dx.doi.org/10.1017/S0950268800001485
Language: English
Additional information: © 1996 Cambridge University Press
Keywords: HUMAN-IMMUNODEFICIENCY-VIRUS, MULTICENTER AIDS COHORT, HOMOSEXUAL MEN, DISEASE PROGRESSION, INCUBATION PERIOD, BLOOD PRODUCTS, INFECTION, HEMOPHILIACS, TRANSFUSION, PREDICTORS
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/101627
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