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A systematic review exploring challenges of informed consent processes in antipsychotic prescribing

Thompson, Jemima; Grunwald, Lisa M; (2023) A systematic review exploring challenges of informed consent processes in antipsychotic prescribing. Psychosis - Psychological, Social and Integrative Approaches 10.1080/17522439.2023.2285967. (In press). Green open access

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Abstract

Introduction: Informed consent is the process whereby individuals make decisions about their medical care. Information provision, presumption of capability and absence of coercion are three fundamental assumptions required to provide informed consent. Informed consent may be complex to achieve in the context of antipsychotic prescribing. This systematic review aimed to explore challenges relating to informed consent processes in antipsychotic prescribing in the UK. Method: This was a systematic review of the literature relating to informed consent in antipsychotic prescribing in community settings. Data were analysed using Framework analysis. Results: Twenty-eight articles were included. Information provision has been perceived as lacking for a long time. Capacity has often not been assumed and loss of capacity has sometimes been viewed as permanent. Power imbalances associated with prescriber status and legal framework surrounding the Mental Health Act can blur lines between coercion and persuasion. Discussion: Challenges relating to process of informed consent in antipsychotic prescribing have persisted throughout the last few decades. People prescribed antipsychotics need to be made aware of their effects in line with current research. Further research is required to develop models for best practices for informed consent.

Type: Article
Title: A systematic review exploring challenges of informed consent processes in antipsychotic prescribing
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/17522439.2023.2285967
Publisher version: http://dx.doi.org/10.1080/17522439.2023.2285967
Language: English
Additional information: © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http:// creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
Keywords: Social Sciences, Science & Technology, Life Sciences & Biomedicine, Psychology, Clinical, Psychiatry, Psychology, Informed consent, antipsychotics, information, TARDIVE-DYSKINESIA, NEUROLEPTIC MEDICATION, SCHIZOPHRENIA, INFORMATION, PATIENT, PEOPLE, EXPERIENCES, ATTITUDES, FAMILY, TRIAL
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10192404
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