Browse by UCL people
2025
Ahn, Jehyun;
Lee, Eun Hye;
Yoo, Heejin;
Shin, Daeun;
Kang, Heekyoung;
Yim, Sohyun;
Kim, Seongmi;
... K-ROAD study group; + view all
(2025)
Tailoring thresholds for interpreting plasma p-tau217 levels.
Journal of Neurology, Neurosurgery and Psychiatry
10.1136/jnnp-2025-335830.
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Ao, Jiarui;
Picard, Cynthia;
Auld, Daniel;
Zetterberg, Henrik;
Brinkmalm, Ann;
Blennow, Kaj;
Villeneuve, Sylvia;
... PREVENT-AD research group; + view all
(2025)
Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer’s disease.
Molecular Psychiatry
, 30
pp. 2810-2820.
10.1038/s41380-024-02884-z.
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Belder, Christopher RS;
Boche, Delphine;
Nicoll, James AR;
Jaunmuktane, Zane;
Zetterberg, Henrik;
Schott, Jonathan M;
Barkhof, Frederik;
(2025)
Amyloid-related iatrogenic atrophy of the brain: data transparency is an urgent safety priority – Authors' reply.
The Lancet Neurology
, 24
(3)
p. 190.
10.1016/S1474-4422(25)00030-4.
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Cacciaglia, R;
Falcón, C;
Benavides, GS;
Brugulat-Serrat, A;
Alomà, MM;
Calvet, MS;
Molinuevo, JL;
... The ALFA study; + view all
(2025)
Soluble Aβ pathology predicts neurodegeneration and cognitive decline independently on p-tau in the earliest Alzheimer's continuum: Evidence across two independent cohorts.
Alzheimer's and Dementia
, Article e14415. 10.1002/alz.14415.
(In press).
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Carrol, D;
Busse, WW;
Frye, CJ;
Klaus, DR;
Bach, JC;
Floerke, H;
Bendlin, BB;
... Rosenkranz, MA; + view all
(2025)
Regional brain structural alterations in reward and salience networks in asthma.
Brain, Behavior, and Immunity
, 126
pp. 80-97.
10.1016/j.bbi.2025.01.028.
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De Strooper, Bart;
Haass, Christian;
Hardy, John;
Zetterberg, Henrik;
(2025)
The regulatory rollercoaster continues—EMA refuses donanemab.
The Lancet
, 405
(10492)
pp. 1810-1812.
10.1016/S0140-6736(25)00833-5.
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Delvenne, Aurore;
Gobom, Johan;
Reus, Lianne M;
Dobricic, Valerija;
Ten Kate, Mara;
Schindler, Suzanne E;
Ramakers, Inez;
... Vos, Stephanie JB; + view all
(2025)
Cerebrospinal fluid proteomic profiling of cognitively unimpaired individuals with suspected non-Alzheimer's disease pathophysiology.
Brain Communications
, 7
(4)
, Article fcaf253. 10.1093/braincomms/fcaf253.
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Eratne, Dhamidhu;
Li, Qiao-Xin;
Lewis, Courtney;
Dang, Christa;
Kang, Matthew JY;
Grewal, Jasleen;
Loi, Samantha;
... MiND Study Group; + view all
(2025)
Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical cohort.
Journal of Neurology
, 272
, Article 25. 10.1007/s00415-024-12732-3.
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Gogniat, Marissa A;
Khan, Omair A;
Ratangee, Brina;
Bolton, Corey J;
Zhang, Panpan;
Liu, Dandan;
Pechman, Kimberly R;
... Jefferson, Angela L; + view all
(2025)
Cross-Sectional and Longitudinal Associations of Neighborhood Disadvantage With Fluid Biomarkers of Neuroinflammation and Neurodegeneration.
Neurology
, 105
(2)
, Article e213770. 10.1212/WNL.0000000000213770.
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Heneka, Michael T;
Van der Flier, Wiesje M;
Jessen, Frank;
Hoozemanns, Jeroen;
Thal, Dietmar Rudolf;
Boche, Delphine;
Brosseron, Frederic;
... Riechers, Sean-Patrick; + view all
(2025)
Neuroinflammation in Alzheimer disease.
Nature Reviews Immunology
, 25
pp. 321-352.
10.1038/s41577-024-01104-7.
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Knorr, Ulla;
Simonsen, Anja Hviid;
Nilsson, Johanna;
Brinkmalm, Ann;
Zetterberg, Henrik;
Blennow, Kaj;
Knudsen, Mark Bech;
... Kessing, Lars Vedel; + view all
(2025)
Associations between cerebrospinal fluid synaptic protein biomarkers and cognitive function in bipolar disorder.
Journal of Psychiatric Research
, 184
pp. 288-296.
10.1016/j.jpsychires.2025.03.005.
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Kodosaki, E;
Zetterberg, H;
Heslegrave, A;
(2025)
Current Methods in Clinical Alzheimer’s Disease Research and Diagnosis.
Molecular Diagnosis and Therapy
10.1007/s40291-025-00789-3.
(In press).
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Leuzy, Antoine;
Bollack, Ariane;
Pellegrino, Daniela;
Teunissen, Charlotte E;
La Joie, Renaud;
Rabinovici, Gil D;
Franzmeier, Nicolai;
... Farrar, Gill; + view all
(2025)
Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease.
Alzheimer's & Dementia
, 21
(3)
, Article e14528. 10.1002/alz.14528.
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Liu, Ella;
Jones, Sherri Lee;
Light, Victoria;
Teunissen, Charlotte;
Bouzigues, Arabella;
Russell, Lucy L;
Foster, Phoebe H;
... Ducharme, Simon; + view all
(2025)
Accuracy of blood-based neurofilament light to different genetic frontotemporal dementia from primary psychiatric disorders.
Journal of Alzheimer’s Disease
, 106
(4)
pp. 1337-1354.
10.1177/13872877251352103.
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Ly, Monica T;
Altaras, Caroline;
Tripodis, Yorghos;
Adler, Charles H;
Balcer, Laura J;
Bernick, Charles;
Zetterberg, Henrik;
... Alosco, Michael L; + view all
(2025)
Single- versus two-test criteria for cognitive impairment: associations with CSF and imaging markers in former American football players.
The Clinical Neuropsychologist
10.1080/13854046.2025.2451828.
(In press).
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Michaëlsson, Isak;
Hallén, Tobias;
Farahmand, Dan;
Mahamud, Ubah;
Blennow, Kaj;
Zetterberg, Henrik;
Jakola, Asgeir S;
(2025)
Assessing Brain Injury After Extra-Axial Brain Tumor Resection: Circulating Neurofilament Light Levels, Neurological Deficits, and Fatigue.
Neurosurgery
10.1227/neu.0000000000003612.
(In press).
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Mossavar-Rahmani, Y;
Hyun, N;
Hakun, JG;
Katz, MJ;
Pavlovic, JM;
Zetterberg, H;
Wang, Z;
... Shaw, PA; + view all
(2025)
The effects of the Multicultural Healthy Diet on cognitive decline and Alzheimer's disease risk: a phase II randomized controlled trial in middle-aged adults.
The American Journal of Clinical Nutrition
, 122
(1)
pp. 48-59.
10.1016/j.ajcnut.2025.05.011.
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Pilotto, Andrea;
Quaresima, Virginia;
Trasciatti, Chiara;
Tolassi, Chiara;
Bertoli, Diego;
Mordenti, Cristina;
Galli, Alice;
... Padovani, Alessandro; + view all
(2025)
Plasma p-tau217 in Alzheimer’s disease: Lumipulse and ALZpath SIMOA head-to-head comparison.
Brain
, 148
(2)
pp. 408-415.
10.1093/brain/awae368.
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Pussinen, Christel;
Anttonen, Mikko;
Wihersaari, Lauri;
Tiainen, Marjaana;
Reinikainen, Matti;
Hästbacka, Johanna;
Zetterberg, Henrik;
... Skrifvars, Markus B; + view all
(2025)
Neurofilament light chain evaluated with a new automated commercially available method for outcome prediction in out-of-hospital cardiac arrest patients.
Resuscitation
, 215
, Article 110698. 10.1016/j.resuscitation.2025.110698.
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Sanchez, Erlan;
Coughlan, Gillian T;
Wilkinson, Tim;
Ramirez, Joel;
Mirza, Saira Saeed;
Baril, Andrée-Ann;
Dilliott, Allison A;
... ONDRI Investigators; + view all
(2025)
Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases.
Neurology
, 104
(7)
, Article e213438. 10.1212/WNL.0000000000213438.
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Sanfilippo, Cristina;
Castrogiovanni, Paola;
Imbesi, Rosa;
Vecchio, Michele;
Vinciguerra, Manlio;
Blennow, Kaj;
Zetterberg, Henrik;
(2025)
Sex-specific modulation of FOLR1 and its cycle enzyme genes in Alzheimer’s disease brain regions.
Metabolic Brain Disease
, 40
(4)
, Article 163. 10.1007/s11011-025-01578-x.
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Scahill, Rachael I;
Farag, Mena;
Murphy, Michael J;
Hobbs, Nicola Z;
Leocadi, Michela;
Langley, Christelle;
Knights, Harry;
... Tabrizi, Sarah J; + view all
(2025)
Somatic CAG repeat expansion in blood associates with biomarkers of neurodegeneration in Huntington's disease decades before clinical motor diagnosis.
Nature Medicine
10.1038/s41591-024-03424-6.
(In press).
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Selma-Gonzalez, Judit;
Rubio-Guerra, Sara;
García-Castro, Jesús;
Vera-Campuzano, Elena;
Sala, Isabel;
Sánchez-Saudinós, María Belén;
Zhu, Nuole;
... Illan-Gala, Ignacio; + view all
(2025)
Association of Plasma Phosphorylated Tau 217 With Clinical Deterioration Across Alzheimer Disease Stages.
Neurology
, 105
(1)
, Article e213769. 10.1212/WNL.0000000000213769.
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Sogorb-Esteve, Aitana;
Weiner, Sophia;
Simrén, Joel;
Swift, Imogen J;
Bocchetta, Martina;
Todd, Emily G;
Cash, David M;
... GENFI; + view all
(2025)
Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypes.
Science Translational Medicine
, 17
(784)
, Article eadm9654. 10.1126/scitranslmed.adm9654.
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Terracciano, Antonio;
Walker, Keenan A;
An, Yang;
Bilgel, Murat;
Sutin, Angelina R;
Luchetti, Martina;
Karakose, Selin;
... Resnick, Susan M; + view all
(2025)
Loneliness and biomarkers of Alzheimer's disease, axonal damage, and astrogliosis: A coordinated analysis of two longitudinal cohorts.
The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences
, Article gbaf006. 10.1093/geronb/gbaf006.
(In press).
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Therriault, J;
Brum, WS;
Trudel, L;
Macedo, AC;
Bitencourt, FV;
Martins-Pfeifer, CC;
Nakouzi, M;
... Rosa-Neto, P; + view all
(2025)
Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis.
Lancet Neurology
, 24
(9)
pp. 740-752.
10.1016/S1474-4422(25)00227-3.
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Wiels, WA;
Oomens, JE;
Engelborghs, S;
Baeken, C;
Von Arnim, CAF;
Boada, M;
Didic, M;
... Ramakers, IH; + view all
(2025)
Depressive Symptoms and Amyloid Pathology.
JAMA Psychiatry
, 82
(3)
pp. 296-310.
10.1001/jamapsychiatry.2024.4305.
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Yun, Jihwan;
Shin, Daeun;
Lee, Eun Hye;
Kim, Jun Pyo;
Ham, Hongki;
Gu, Yuna;
Chun, Min Young;
... Jang, Hyemin; + view all
(2025)
Temporal Dynamics and Biological Variability of Alzheimer Biomarkers.
JAMA Neurology
, 82
(4)
pp. 384-396.
10.1001/jamaneurol.2024.5263.
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Zhang, Jingwei;
Wang, Zicong;
Liu, Yuan;
Zetterberg, Henrik;
Li, Lingjun;
(2025)
Boosting Quantification of N-Glycans by an Enhanced Isobaric Multiplex Reagents for Carbonyl-Containing Compound (SUGAR) Tagging Strategy.
Journal of the American Society for Mass Spectrometry
, Article jasms.5c00153. 10.1021/jasms.5c00153.
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2024
Alagaratnam, J;
Stöhr, W;
Hamlyn, E;
Porter, K;
Toombs, J;
Heslegrave, A;
Zetterberg, H;
... Fidler, S; + view all
(2024)
Impact of interrupting antiretroviral therapy started during primary HIV-1 infection on plasma neurofilament light chain protein, a marker of neuronal injury: The SPARTAC trial.
Journal of Virus Eradication
, 10
(2)
, Article 100381. 10.1016/j.jve.2024.100381.
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Ashton, Nicholas J;
Brum, Wagner S;
Di Molfetta, Guglielmo;
Benedet, Andrea L;
Arslan, Burak;
Jonaitis, Erin;
Langhough, Rebecca E;
... Zetterberg, Henrik; + view all
(2024)
Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology.
JAMA Neurology
10.1001/jamaneurol.2023.5319.
(In press).
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Ashton, Nicholas J;
Di Molfetta, Guglielmo;
Tan, Kübra;
Blennow, Kaj;
Zetterberg, Henrik;
Messing, Albee;
(2024)
Plasma concentrations of glial fibrillary acidic protein, neurofilament light, and tau in Alexander disease.
Neurological Sciences
10.1007/s10072-024-07495-8.
(In press).
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Bastgen, T;
Evers, J;
Oedekoven, C;
Weide, C;
Herzog, L;
Ashton, N;
Zetterberg, H;
... Ross, JA; + view all
(2024)
Repetitive head injuries in German American football players do not change blood-based biomarker candidates for CTE during a single season.
Neurological Research and Practice
, 6
(1)
, Article 13. 10.1186/s42466-024-00307-6.
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Bavato, Francesco;
Barro, Christian;
Schnider, Laura K;
Simrén, Joel;
Zetterberg, Henrik;
Seifritz, Erich;
Quednow, Boris B;
(2024)
Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls.
Molecular Psychiatry
10.1038/s41380-024-02524-6.
(In press).
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Belder, CRS;
Boche, D;
Nicoll, JAR;
Jaunmuktane, Z;
Zetterberg, H;
Schott, JM;
Barkhof, F;
(2024)
Brain volume change following anti-amyloid β immunotherapy for Alzheimer's disease: amyloid-removal-related pseudo-atrophy.
The Lancet Neurology
, 23
(10)
pp. 1025-1034.
10.1016/S1474-4422(24)00335-1.
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Bieger, Andrei;
Brum, Wagner S;
Borelli, Wyllians V;
Therriault, Joseph;
De Bastiani, Marco A;
Moreira, Amanda G;
Benedet, Andrea L;
... Alzheimer's Disease Neuroimaging Initiative; + view all
(2024)
Influence of Different Diagnostic Criteria on Alzheimer Disease Clinical Research.
Neurology
, 103
(5)
, Article e209753. 10.1212/WNL.0000000000209753.
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Bjursten, Sara;
Zhao, Zhiyuan;
Al Remawi, Hifaa;
Studahl, Marie;
Pandita, Ankur;
Simrén, Joel;
Zetterberg, Henrik;
... Levin, Max; + view all
(2024)
Concentrations of S100B and neurofilament light chain in blood as biomarkers for checkpoint inhibitor–induced CNS inflammation.
eBioMedicine
, 100
, Article 104955. 10.1016/j.ebiom.2023.104955.
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Brum, Wagner S;
Cullen, Nicholas C;
Therriault, Joseph;
Janelidze, Shorena;
Rahmouni, Nesrine;
Stevenson, Jenna;
Servaes, Stijn;
... Hansson, Oskar; + view all
(2024)
A blood-based biomarker workflow for optimal tau-PET referral in memory clinic settings.
Nature Communications
, 15
(1)
, Article 2311. 10.1038/s41467-024-46603-2.
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Chong, JR;
Chai, YL;
Yam, ATY;
Hilal, S;
Vrooman, H;
Venketasubramanian, N;
Blennow, K;
... Lai, MKP; + view all
(2024)
Association of plasma GFAP with elevated brain amyloid is dependent on severity of white matter lesions in an Asian cognitively impaired cohort.
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
, 16
(2)
, Article e12576. 10.1002/dad2.12576.
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Cook, N;
Driscoll, I;
Gaitán, JM;
Glittenberg, M;
Betthauser, TJ;
Carlsson, CM;
Johnson, SC;
... Okonkwo, OC; + view all
(2024)
Amyloid-β positivity is less prevalent in cognitively unimpaired KLOTHO KL-VS heterozygotes.
Journal of Alzheimer’s Disease
, 102
(2)
pp. 480-490.
10.1177/13872877241289785.
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De Strooper, Bart;
Haass, Christian;
Hardy, John;
Zetterberg, Henrik;
(2024)
Divisions over the regulation of lecanemab.
The Lancet
, 404
(10468)
pp. 2160-2161.
10.1016/S0140-6736(24)02513-3.
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Dittrich, Anna;
Westman, Eric;
Shams, Sara;
Skillbäck, Tobias;
Zetterberg, Henrik;
Blennow, Kaj;
Zettergren, Anna;
... Kern, Silke; + view all
(2024)
Proportion of Community-Dwelling Individuals Older Than 70 Years Eligible for Lecanemab Initiation: The Gothenburg H70 Birth Cohort Study.
Neurology
, 102
(9)
, Article e209402. 10.1212/WNL.0000000000209402.
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Emeršič, Andreja;
Karikari, Thomas K;
Kac, Przemysław R;
Gonzalez-Ortiz, Fernando;
Dulewicz, Maciej;
Ashton, Nicholas J;
Brecl Jakob, Gregor;
... Blennow, Kaj; + view all
(2024)
Biomarkers of tau phosphorylation state are associated with the clinical course of multiple sclerosis.
Multiple Sclerosis and Related Disorders
, 90
, Article 105801. 10.1016/j.msard.2024.105801.
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Ferrari-Souza, JP;
Brum, WS;
Hauschild, LA;
Da Ros, LU;
Ferreira, PCL;
Bellaver, B;
Leffa, DT;
... Zimmer, ER; + view all
(2024)
Vascular risk burden is a key player in the early progression of Alzheimer's disease.
Neurobiology of Aging
, 136
pp. 88-98.
10.1016/j.neurobiolaging.2023.12.008.
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Frank, Brandon;
Walsh, Michael;
Hurley, Landon;
Groh, Jenna;
Blennow, Kaj;
Zetterberg, Henrik;
Tripodis, Yorghos;
... Alosco, Michael L; + view all
(2024)
Cognition Mediates the Association Between Cerebrospinal Fluid Biomarkers of Amyloid and P-Tau and Neuropsychiatric Symptoms.
Journal of Alzheimer's Disease
, 100
(3)
pp. 1055-1073.
10.3233/JAD-240125.
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Franzmeier, Nicolai;
Dehsarvi, Amir;
Steward, Anna;
Biel, Davina;
Dewenter, Anna;
Roemer, Sebastian Niclas;
Wagner, Fabian;
... Schöll, Michael; + view all
(2024)
Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's disease.
Nature Communications
, 15
(1)
, Article 202. 10.1038/s41467-023-44374-w.
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Friberg, Susanna;
Lindblad, Caroline;
Zeiler, Frederick A;
Zetterberg, Henrik;
Granberg, Tobias;
Svenningsson, Per;
Piehl, Fredrik;
(2024)
Fluid biomarkers of chronic traumatic brain injury.
Nature Reviews Neurology
, 20
pp. 671-684.
10.1038/s41582-024-01024-z.
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Garcia-Cordero, Indira;
Vasilevskaya, Anna;
Taghdiri, Foad;
Khodadadi, Mozhgan;
Mikulis, David;
Tarazi, Apameh;
Mushtaque, Asma;
... Tartaglia, Maria C; + view all
(2024)
Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions.
Journal of Neurology
, 271
pp. 4180-4190.
10.1007/s00415-024-12340-1.
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Gobom, Johan;
Brinkmalm, Ann;
Brinkmalm, Gunnar;
Blennow, Kaj;
Zetterberg, Henrik;
(2024)
Alzheimer's disease biomarker analysis using targeted mass spectrometry.
Molecular & Cellular Proteomics
, 23
(2)
, Article 100721. 10.1016/j.mcpro.2024.100721.
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Gómez-Pascual, A;
Naccache, T;
Xu, J;
Hooshmand, K;
Wretlind, A;
Gabrielli, M;
Lombardo, MT;
... Legido-Quigley, C; + view all
(2024)
Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease.
Computers in Biology and Medicine
, 176
, Article 108588. 10.1016/j.compbiomed.2024.108588.
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Gonzalez-Ortiz, Fernando;
Kirsebom, Bjørn-Eivind;
Contador, José;
Tanley, Jordan E;
Selnes, Per;
Gísladóttir, Berglind;
Pålhaugen, Lene;
... Blennow, Kaj; + view all
(2024)
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease.
Nature Communications
, 15
, Article 2908. 10.1038/s41467-024-47286-5.
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Gustafsson, Johan;
Robinson, Jonathan L;
Zetterberg, Henrik;
Nielsen, Jens;
(2024)
Brain energy metabolism is optimized to minimize the cost of enzyme synthesis and transport.
Proceedings of the National Academy of Sciences (PNAS)
, 121
(7)
, Article e2305035121. 10.1073/pnas.2305035121.
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Hale, MR;
Langhough, R;
Du, L;
Hermann, BP;
Van Hulle, CA;
Carboni, M;
Kollmorgen, G;
... Mueller, KD; + view all
(2024)
Associations between recall of proper names in story recall and CSF amyloid and tau in adults without cognitive impairment.
Neurobiology of Aging
, 133
pp. 87-98.
10.1016/j.neurobiolaging.2023.09.018.
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Jha, D;
Blennow, K;
Zetterberg, H;
Savas, JN;
Hanrieder, J;
(2024)
Spatial neurolipidomics—MALDI mass spectrometry imaging of lipids in brain pathologies.
Journal of Mass Spectrometry
, 59
(3)
, Article e5008. 10.1002/jms.5008.
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Kac, Przemysław R;
González-Ortiz, Fernando;
Emeršič, Andreja;
Dulewicz, Maciej;
Koutarapu, Srinivas;
Turton, Michael;
An, Yang;
... Karikari, Thomas K; + view all
(2024)
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease neuropathology.
Nature Communications
, 15
(1)
, Article 2615. 10.1038/s41467-024-46876-7.
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Kalaria, R;
Maestre, G;
Mahinrad, S;
Acosta, DM;
Akinyemi, RO;
Alladi, S;
Allegri, RF;
... Ismail, O; + view all
(2024)
The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact.
Alzheimer's and Dementia
10.1002/alz.13836.
(In press).
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Khalil, Michael;
Teunissen, Charlotte E;
Lehmann, Sylvain;
Otto, Markus;
Piehl, Fredrik;
Ziemssen, Tjalf;
Bittner, Stefan;
... Kuhle, Jens; + view all
(2024)
Neurofilaments as biomarkers in neurological disorders - towards clinical application.
Nature Reviews Neurology
, 20
(5)
pp. 269-287.
10.1038/s41582-024-00955-x.
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Leckey, Claire A;
Coulton, John B;
Giovannucci, Tatiana A;
He, Yingxin;
Aslanyan, Aram;
Laban, Rhiannon;
Heslegrave, Amanda;
... Paterson, Ross W; + view all
(2024)
Cerebrospinal fluid neurofilament light chain profiling and quantitation in neurological diseases.
Brain Communications
, 6
(3)
, Article fcae132. 10.1093/braincomms/fcae132.
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Li, Ge;
Iliff, Jeffrey;
Shofer, Jane;
Mayer, Cynthia L;
Meabon, James;
Cook, David;
Pagulayan, Kathleen F;
... Peskind, Elaine R; + view all
(2024)
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A feasibility study of the combination of intranasal insulin with dulaglutide for cognition in older adults with metabolic syndrome at high dementia risk – Study rationale and design.
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Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration: The H70 Birth Cohort Study in Gothenburg.
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ADVANCE-TBI study protocol: traumatic brain injury outcomes in UK military personnel serving in Afghanistan between 2003 and 2014 - a longitudinal cohort study.
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A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter.
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Transient Changes in the Plasma of Astrocytic and Neuronal Injury Biomarkers in COVID-19 Patients without Neurological Syndromes.
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Plasma Biomarkers of Alzheimer Disease in Women With and Without HIV.
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Reference Data for Attentional, Executive, Linguistic, and Visual Processing Tests Obtained from Cognitively Healthy Individuals with Normal Alzheimer's Disease Cerebrospinal Fluid Biomarker Levels.
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Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults.
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Analytical and clinical validation of a blood progranulin ELISA in frontotemporal dementias.
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Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid.
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European Journal of Neurology
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Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down syndrome.
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Alzheimer's & Dementia
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Cellular and Molecular Neurobiology
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Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances.
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Plasma neurofilament light chain level is not a biomarker of Charcot–Marie–Tooth disease progression: Results of 3-year follow-up study.
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Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis.
Multiple Sclerosis Journal
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Cerebrospinal fluid catecholamines in Alzheimer's disease patients with and without biological disease.
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The Neuroimmune Response to Surgery – An Exploratory Study of Trauma-Induced Changes in Innate Immunity and Heart Rate Variability.
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Functional Applications of Stable Tau Oligomers in Cell Biology and Electrophysiology Studies.
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A Validated Method to Prepare Stable Tau Oligomers.
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Hossain, Iftakher;
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Tau as a fluid biomarker of concussion and neurodegeneration.
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GFAp and tau protein as predictors of neurological outcome after out-of-hospital cardiac arrest: A post hoc analysis of the COMACARE trial.
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Plasma Cystatin C correlates with plasma NfL levels and predicts disease progression in Parkinson's disease.
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Cerebrospinal fluid proteomic study of two bipolar disorder cohorts.
Molecular Psychiatry
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Examining four blood biomarkers for the detection of acute intracranial abnormalities following mild traumatic brain injury in older adults.
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Jaervilehto, Julius;
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Serum Creatine, Not Neurofilament Light, Is Elevated in CHCHD10-Linked Spinal Muscular Atrophy.
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Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease.
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Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma Aβ42/Aβ40 and p-tau.
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
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Shared CSF Biomarker Profile in Idiopathic Normal Pressure Hydrocephalus and Subcortical Small Vessel Disease.
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Cerebrospinal fluid amyloid precursor protein as a potential biomarker of fatigue in multiple sclerosis: A pilot study.
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No increase of serum neurofilament light in relapsing-remitting multiple sclerosis patients switching from standard to extended-interval dosing of natalizumab.
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Crosswalk study on blood collection-tube types for Alzheimer's disease biomarkers.
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The Influence of Orthopedic Surgery on Circulating Metabolite Levels, and their Associations with the Incidence of Postoperative Delirium.
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A Neuropsychological Perspective on Defining Cognitive Impairment in the Clinical Study of Alzheimer's Disease: Towards a More Continuous Approach.
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Diagnostic value of serum versus plasma phospho-tau for Alzheimer's disease.
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Association of plasma neurofilament light chain with disease activity in chronic inflammatory demyelinating polyradiculoneuropathy.
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Editorial: Blood Biomarkers of Neurodegenerative Diseases.
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Alzheimer's disease diagnosis and management: Perspectives from around the world.
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Blood-brain barrier dysfunction and reduced cerebrospinal fluid levels of soluble amyloid precursor protein-β in patients with subcortical small-vessel disease.
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Cardiac troponin T is elevated and increases longitudinally in ALS patients.
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Neurofilament light chain and total tau in the differential diagnosis and prognostic evaluation of acute and chronic inflammatory polyneuropathies.
European Journal of Neurology
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Alzheimer's disease related biomarkers in bipolar disorder - A longitudinal one-year case-control study.
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Small extracellular vesicles in plasma reveal molecular effects of modified Mediterranean-ketogenic diet in participants with mild cognitive impairment.
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Brain injury markers in blood predict signs of hypoxic ischaemic encephalopathy on head computed tomography after cardiac arrest.
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Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus.
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Correlation between CD4/CD8 ratio and neurocognitive performance during early HIV infection.
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Isotopic N,N-dimethyl leucine tags for absolute quantification of clusterin and apolipoprotein E in Alzheimer's disease.
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Altered Balance of Reelin Proteolytic Fragments in the Cerebrospinal Fluid of Alzheimer's Disease Patients.
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Cerebrospinal fluid biomarkers that reflect clinical symptoms in idiopathic normal pressure hydrocephalus patients.
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Concordance of Alzheimer's Disease-Related Biomarkers Between Intraventricular and Lumbar Cerebrospinal Fluid in Idiopathic Normal Pressure Hydrocephalus.
Journal of Alzheimer's Disease
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Inflammation, tau pathology, and synaptic integrity associated with sleep spindles and memory prior to β-amyloid positivity.
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Comparing the effect of xenon and sevoflurane anesthesia on postoperative neural injury biomarkers: a randomized controlled trial.
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Neurofilament Light in Cerebrospinal Fluid is Associated With Disease Staging in European Lyme Neuroborreliosis.
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Increased intrathecal neurofilament light and immunoglobulin M predict severe disability in relapsing-remitting multiple sclerosis.
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Neurofilament Light Regulates Axon Caliber, Synaptic Activity, and Organelle Trafficking in Cultured Human Motor Neurons.
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Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.
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Exploring common genetic contributors to neuroprotection from amyloid pathology.
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Association of Plasma Biomarker Levels With Their CSF Concentration and the Number and Severity of Concussions in Professional Athletes.
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CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals.
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Decreased Electroencephalography Global Field Synchronization in Slow-Frequency Bands Characterizes Synaptic Dysfunction in Amnestic Subtypes of Mild Cognitive Impairment.
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ASIC-E4: Interplay of Beta-Amyloid, Synaptic Density and Neuroinflammation in Cognitively Normal Volunteers With Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease – Study Protocol and Baseline Characteristics.
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A translatable RNAi-driven gene therapy silences PMP22/Pmp22 genes and improves neuropathy in CMT1A mice.
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British Journal of Haematology
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A Longitudinal Study of Plasma pTau181 in Mild Cognitive Impairment with Lewy Bodies and Alzheimer's Disease.
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Investigating the use of plasma pTau181 in retired contact sports athletes.
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Combining biomarkers for prognostic modelling of Parkinson's disease.
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Assessing Neurofilaments as Biomarkers of Neuroprotection in Progressive Multiple Sclerosis: From the MS-STAT Randomized Controlled Trial.
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CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia.
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Serum Neurofilament Light is elevated in COVID-19 Positive Adults in the ICU and is associated with Co-Morbid Cardiovascular Disease, Neurological Complications, and Acuity of Illness.
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2015
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Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls.
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Do cerebrospinal fluid transfer methods affect measured amyloid β42, total tau, and phosphorylated tau in clinical practice?
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Using florbetapir positron emission tomography to explore cerebrospinal fluid cut points and gray zones in small sample sizes.
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Wild, EJ;
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Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.
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2014
Ahmed, RM;
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Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.
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Magdalinou, N;
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Toombs, J;
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von Otter, M;
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2013
Hölttä, M;
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Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer's Disease.
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2012
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CSF T-Tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease.
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Hölttä, M;
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Mattsson, N;
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BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system.
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Neselius, S;
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CSF-biomarkers in Olympic boxing: diagnosis and effects of repetitive head trauma.
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Palmqvist, S;
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Comparison of brief cognitive tests and CSF biomarkers in predicting Alzheimer's disease in mild cognitive impairment: six-year follow-up study.
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Petkova, VI;
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Rubber hands feel touch, but not in blind individuals.
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Pillai, A;
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Plasma BDNF levels vary in relation to body weight in females.
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2011
Zetterberg, H;
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Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans.
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2010
Gao, CM;
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Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease.
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2009
Buchhave, P;
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Zetterberg, H;
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Longitudinal study of CSF biomarkers in patients with Alzheimer's disease.
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