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Detection of α-Synuclein in Biological Samples Using Mass Spectrometry

Brinkmalm, A; Öhrfelt, A; Bhattacharjee, P; Zetterberg, H; (2019) Detection of α-Synuclein in Biological Samples Using Mass Spectrometry. In: Alpha-Synuclein Methods and Protocols. (pp. 209-220). Humana Press: New York, NY, USA. Green open access

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Abstract

Here we describe a method using mass spectrometry to characterize and quantify immuno-enriched α-synuclein forms from biochemically fractionated brain tissue.

Type: Book chapter
Title: Detection of α-Synuclein in Biological Samples Using Mass Spectrometry
ISBN-13: 978-1-4939-9123-5
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-1-4939-9124-2_16
Publisher version: https://doi.org/10.1007/978-1-4939-9124-2_16
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Brain, CSF, Mass spectrometry, Parkinson’s disease, α-Synuclein
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/10069669
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