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Comparison of brief cognitive tests and CSF biomarkers in predicting Alzheimer's disease in mild cognitive impairment: six-year follow-up study

Palmqvist, S; Hertze, J; Minthon, L; Wattmo, C; Zetterberg, H; Blennow, K; Londos, E; (2012) Comparison of brief cognitive tests and CSF biomarkers in predicting Alzheimer's disease in mild cognitive impairment: six-year follow-up study. PLoS One , 7 (6) , Article e38639. 10.1371/journal.pone.0038639. Green open access

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Abstract

Early identification of Alzheimer's disease (AD) is needed both for clinical trials and in clinical practice. In this study, we compared brief cognitive tests and cerebrospinal fluid (CSF) biomarkers in predicting conversion from mild cognitive impairment (MCI) to AD.

Type: Article
Title: Comparison of brief cognitive tests and CSF biomarkers in predicting Alzheimer's disease in mild cognitive impairment: six-year follow-up study
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0038639
Publisher version: http://dx.doi.org/10.1371/journal.pone.0038639
Language: English
Additional information: © 2012 Palmqvist et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3382225
Keywords: Aged, Aged, 80 and over, Alzheimer Disease, Amyloid beta-Peptides, Biological Markers, Cognition Disorders, Dementia, Female, Follow-Up Studies, Humans, Male, Middle Aged, Mild Cognitive Impairment, Neuropsychological Tests, ROC Curve, tau Proteins
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/1411978
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