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Blood biomarkers for HIV infection with focus on neurologic complications-A review

Hagberg, Lars; Edén, Arvid; Zetterberg, Henrik; Price, Richard W; Gisslén, Magnus; (2022) Blood biomarkers for HIV infection with focus on neurologic complications-A review. Acta Neurologica Scandinavica 10.1111/ane.13629. (In press). Green open access

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Abstract

Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA concentrations, CD4 +T-cell count, and neurofilament light chain protein (NfL) concentration, along with tests for opportunistic infections can provide important information for clinical decisions.

Type: Article
Title: Blood biomarkers for HIV infection with focus on neurologic complications-A review
Location: Denmark
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/ane.13629
Publisher version: https://doi.org/10.1111/ane.13629
Language: English
Additional information: © 2022 The Authors. Acta Neurologica Scandinavica published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Keywords: HIV, blood biomarkers, neurology
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10147765
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