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Longitudinal study of CSF biomarkers in patients with Alzheimer's disease

Buchhave, P; Blennow, K; Zetterberg, H; Stomrud, E; Londos, E; Andreasen, N; Minthon, L; (2009) Longitudinal study of CSF biomarkers in patients with Alzheimer's disease. PLoS One , 4 (7) , Article e6294. 10.1371/journal.pone.0006294. Green open access

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Abstract

The CSF biomarkers tau and Abeta42 can identify patients with AD, even during the preclinical stages. However, previous studies on longitudinal changes of tau and Abeta42 in individual patients with AD and elderly controls report somewhat inconsistent results.

Type: Article
Title: Longitudinal study of CSF biomarkers in patients with Alzheimer's disease
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0006294
Publisher version: http://dx.doi.org/10.1371/journal.pone.0006294
Language: English
Additional information: © 2009 Buchhave et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC2707615
Keywords: Aged, Aged, 80 and over, Alzheimer Disease, Amyloid beta-Peptides, Biological Markers, Case-Control Studies, Cohort Studies, Female, Humans, Longitudinal Studies, Male, Middle Aged, tau Proteins
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases
URI: https://discovery.ucl.ac.uk/id/eprint/1411805
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