Browse by UCL Department: listings for include files
- UCL (198993)
- UCL (198993)
- Provost and Vice Provost Offices (197752)
- School of Life and Medical Sciences (96774)
- Faculty of Medical Sciences (21915)
- Cancer Institute (4089)
- Research Department of Cancer Bio (590)
- Cancer Institute (4089)
- Faculty of Medical Sciences (21915)
- School of Life and Medical Sciences (96774)
- Provost and Vice Provost Offices (197752)
- UCL (198993)
Number of items at this level: 590.
A
Aalto, AL;
Mohan, AK;
Schwintzer, L;
Kupka, S;
Kietz, C;
Walczak, H;
Broemer, M;
(2018)
M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila.
Cell Death & Differentiation
10.1038/s41418-018-0164-x.
(In press).
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Abbosh, Christopher;
Frankell, Alexander M;
Harrison, Thomas;
Kisistok, Judit;
Garnett, Aaron;
Johnson, Laura;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2023)
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
, 616
(7957)
pp. 553-562.
10.1038/s41586-023-05776-4.
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Abbosh, C;
Birkbak, NJ;
Wilson, GA;
Jamal-Hanjani, M;
Constantin, T;
Salari, R;
Le Quesne, J;
... Dessimoz, C; + view all
(2017)
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature
, 545
pp. 446-451.
10.1038/nature22364.
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AbdulJabbar, K;
Raza, SEA;
Rosenthal, R;
Jamal-Hanjani, M;
Veeriah, S;
Akarca, A;
Lund, T;
... Yuan, Y; + view all
(2020)
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma.
Nature Medicine
, 26
pp. 1054-1062.
10.1038/s41591-020-0900-x.
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Al Shareef, Zainab;
Kardooni, Hoda;
Murillo-Garzón, Virginia;
Domenici, Giacomo;
Stylianakis, Emmanouil;
Steel, Jennifer H;
Rabano, Miriam;
... Kypta, Robert M; + view all
(2018)
Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1.
Oncogene
, 37
pp. 5305-5324.
10.1038/s41388-018-0294-0.
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Al-Qassab, Hind;
Smith, Mark A;
Irvine, Elaine E;
Guillermet-Guibert, Julie;
Claret, Marc;
Choudhury, Agharul I;
Selman, Colin;
... Withers, Dominic J; + view all
(2009)
Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons.
Cell Metabolism
, 10
(5)
pp. 343-354.
10.1016/j.cmet.2009.09.008.
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Albert, MC;
Uranga-Murillo, I;
Arias, M;
De Miguel, D;
Peña, N;
Montinaro, A;
Varanda, AB;
... Walczak, H; + view all
(2024)
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
Cell Death & Differentiation
10.1038/s41418-024-01278-6.
(In press).
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Aligianni, S;
Lackner, DH;
Klier, S;
Rustici, G;
Wilhelm, BT;
Marguerat, S;
Codlin, S;
... Bahler, J; + view all
(2009)
The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback.
PLoS Genetics
, 5
(8)
, Article e1000626. 10.1371/journal.pgen.1000626.
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Alrasheed, N;
Lee, L;
Ghorani, E;
Henry, JY;
Conde, L;
Chin, M;
Galas-Filipowicz, D;
... Yong, KL; + view all
(2020)
Marrow-Infiltrating Regulatory T Cells Correlate with the Presence of Dysfunctional CD4⁺PD-1⁺ Cells and Inferior Survival in Patients with Newly Diagnosed Multiple Myeloma.
Clinical Cancer Research
, 26
(13)
pp. 3443-3454.
10.1158/1078-0432.CCR-19-1714.
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Alsulami, AF;
Torres, PHM;
Moghul, I;
Arif, SM;
Chaplin, AK;
Vedithi, SC;
Blundell, TL;
(2021)
COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets.
Briefings in Bioinformatics
, 22
(6)
, Article bbab220. 10.1093/bib/bbab220.
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Alsulami, AF;
Thomas, SE;
Jamasb, AR;
Beaudoin, CA;
Moghul, I;
Bannerman, B;
Copoiu, L;
... Blundell, TL; + view all
(2021)
SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets.
Briefings in Bioinformatics
, 22
(2)
pp. 769-780.
10.1093/bib/bbaa404.
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Altshuler, DM;
Durbin, RM;
Abecasis, GR;
Bentley, DR;
Chakravarti, A;
Clark, AG;
Donnelly, P;
... Abecasis, GR; + view all
(2015)
A global reference for human genetic variation.
NATURE
, 526
(7571)
68-+.
10.1038/nature15393.
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Amaral, AJ;
Andrade, J;
Foxall, RB;
Matoso, P;
Matos, AM;
Soares, RS;
Rocha, C;
... Sousa, AE; + view all
(2017)
miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication.
The EMBO Journal
, 36
(3)
pp. 346-360.
10.15252/embj.201694335.
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Amelina, H;
Moiseeva, V;
Collopy, LC;
Pearson, SR;
Armstrong, CA;
Tomita, K;
(2016)
Sequential and counter-selectable cassettes for fission yeast.
BMC Biotechnology
, 16
, Article 76. 10.1186/s12896-016-0307-4.
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Amelina, H;
Subramaniam, S;
Moiseeva, V;
Armstrong, CA;
Pearson, SR;
Tomita, K;
(2015)
Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation.
BMC Biol
, 13
(1)
, Article 37. 10.1186/s12915-015-0149-x.
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Amodeo, Valeria;
Davies, Timothy;
Martinez-Segura, Amalia;
Clements, Melanie;
Ragdale, Holly Simpson;
Bailey, Andrew;
Silva Dos Santos, Mariana;
... Parrinello, Simona; + view all
(2022)
Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells.
bioRxiv: Cold Spring Harbor, NY, USA.
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Amodeo, Valeria;
Davies, Timothy;
Martinez-Segura, Amalia;
Clements, Melanie P;
Ragdale, Holly Simpson;
Bailey, Andrew;
Dos Santos, Mariana Silva;
... Parrinello, Simona; + view all
(2023)
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells.
Developmental Cell
10.1016/j.devcel.2023.03.021.
(In press).
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Amodeo, V;
A, D;
Betts, J;
Bartesaghi, S;
Zhang, Y;
Richard-Londt, A;
Ellis, M;
... Salomoni, P; + view all
(2017)
A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS.
Cell Reports
, 20
(2)
pp. 411-426.
10.1016/j.celrep.2017.06.047.
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Anandagoda, N;
Roberts, L;
Willis, JCD;
Sarathchandra, P;
Xiao, F;
Jackson, I;
Hertweck, A;
... Lord, GM; + view all
(2020)
Dominant regulation of long-term allograft survival is mediated by microRNA-142.
American Journal of Transplantation
, 20
(10)
pp. 2715-2727.
10.1111/ajt.15907.
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Anandagoda, N;
Willis, JC;
Hertweck, A;
Roberts, LB;
Jackson, I;
Gökmen, MR;
Jenner, RG;
... Lord, GM; + view all
(2019)
microRNA-142-mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance.
Journal of Clinical Investigation
10.1172/JCI124725.
(In press).
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Anguita, E;
Gupta, R;
Olariu, V;
Valk, PJ;
Peterson, C;
Delwel, R;
Enver, T;
(2016)
A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network.
Developmental Biology
, 411
(2)
pp. 277-286.
10.1016/j.ydbio.2016.02.002.
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Annibaldi, A;
Walczak, H;
(2020)
Death Receptors and Their Ligands in Inflammatory Disease and Cancer.
Cold Spring Harbor Perspectives in Biology
10.1101/cshperspect.a036384.
(In press).
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Appios, Anna;
Davies, James;
Sirvent, Sofia;
Henderson, Stephen;
Trzebanski, Sébastien;
Schroth, Johannes;
Law, Morven L;
... Bennett, Clare L; + view all
(2024)
Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity.
Science Immunology
, 9
(99)
, Article eadp0344. 10.1126/sciimmunol.adp0344.
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Areso Zubiaur, Itziar Ibone;
(2020)
Pro-apoptotic TRAIL- and CDK9 inhibition-based cancer therapy.
Doctoral thesis (Ph.D), UCL (University College London).
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Armstrong, CA;
Moiseeva, V;
Collopy, LC;
Pearson, SR;
Ullah, TR;
Xi, ST;
Martin, J;
... Tomita, K; + view all
(2017)
Fission yeast Ccq1 is a modulator of telomerase activity.
Nucleic Acids Res
10.1093/nar/gkx1223.
(In press).
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Armstrong, CA;
Pearson, SR;
Amelina, H;
Moiseeva, V;
Tomita, K;
(2014)
Telomerase activation after recruitment in fission yeast.
Current Biology
, 24
(17)
2006 - 2011.
10.1016/j.cub.2014.07.035.
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Armstrong, CA;
Tomita, K;
(2017)
Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells.
Open Biology
, 7
(3)
, Article 160338. 10.1098/rsob.160338.
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Asghar, US;
Kanani, R;
Roylance, R;
Mittnacht, S;
(2022)
Systematic Review of Molecular Biomarkers Predictive of Resistance to CDK4/6 Inhibition in Metastatic Breast Cancer.
JCO Precision Oncology
, 6
pp. 1-13.
10.1200/po.21.00002.
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Astle, WJ;
Elding, H;
Jiang, T;
Allen, D;
Ruklisa, D;
Mann, AL;
Mead, D;
... Soranzo, N; + view all
(2016)
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
Cell
, 167
(5)
pp. 1415-1429.
10.1016/j.cell.2016.10.042.
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Atkinson, S;
Marguerat, S;
Bitton, D;
Bachand, F;
Rodriguez-Lopez, M;
Rallis, C;
Lemay, J-F;
... Bähler, J; + view all
(2018)
Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast.
RNA
, 24
(9)
pp. 1195-1213.
10.1261/rna.065524.118.
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Au, L;
Hatipoglu, E;
Robert de Massy, M;
Litchfield, K;
Beattie, G;
Rowan, A;
Schnidrig, D;
... TRACERx Renal Consortium; + view all
(2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Cancer Cell
, 39
pp. 1497-1518.
10.1016/j.ccell.2021.10.001.
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Averdam, A;
Petersen, B;
Rosner, C;
Neff, J;
Roos, C;
Eberle, M;
Aujard, F;
... Walter, L; + view all
(2009)
A Novel System of Polymorphic and Diverse NK Cell Receptors in Primates.
PLOS GENET
, 5
(10)
, Article e1000688. 10.1371/journal.pgen.1000688.
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Azzoni, E;
Frontera, V;
Anselmi, G;
Rode, C;
James, C;
Deltcheva, EM;
Demian, AS;
... de Bruijn, MFTR; + view all
(2021)
The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Cell Reports
, 37
(11)
, Article 110103. 10.1016/j.celrep.2021.110103.
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B
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Balogh, E;
Chandler, J;
Varga, M;
Tahoun, M;
Menyhárd, DK;
Schay, G;
Goncalves, T;
... Tory, K; + view all
(2020)
Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis.
Proceedings of the National Academy of Sciences of the United States of America
, 117
(26)
pp. 15137-15147.
10.1073/pnas.2002328117.
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Barbera, JPM;
Clements, M;
Thomas, P;
Rodriguez, T;
Meloy, D;
Kioussis, D;
Beddington, RSP;
(2000)
The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation.
Development
, 127
(11)
pp. 2433-2445.
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Barrett, JE;
Feber, A;
Herrero, J;
Tanic, M;
Wilson, GA;
Swanton, C;
Beck, S;
(2017)
Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.
BMC Bioinformatics
, 18
, Article 354. 10.1186/s12859-017-1753-2.
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Barrington, C;
Finn, R;
Hadjur, S;
(2017)
Cohesin biology meets the loop extrusion model.
Chromosome Research
, 25
(1)
pp. 51-60.
10.1007/s10577-017-9550-3.
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Barrington, C;
Georgopoulou, D;
Pezic, D;
Varsally, W;
Herrero, J;
Hadjur, S;
(2019)
Enhancer accessibility and CTCF occupancy underlie asymmetric TAD architecture and cell type specific genome topology.
Nature Communications
, 10
, Article 2908. 10.1038/s41467-019-10725-9.
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Barrington, C;
Pezic, D;
Hadjur, S;
(2017)
Chromosome structure dynamics during the cell cycle: a structure to fit every phase.
The EMBO Journal
, 36
(17)
, Article e201798014. 10.15252/embj.201798014.
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Bartlett, TE;
Chindera, K;
McDermott, J;
Breeze, CE;
Cooke, WR;
Jones, A;
Reisel, D;
... Widschwendter, M; + view all
(2016)
Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution.
Nature Communications
, 7
, Article ARTN 116. 10.1038/ncomms11620.
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Beck, S;
(2018)
Getting up close and personal with UK genomics and beyond.
Genome Medicine
, 10
(1)
p. 38.
10.1186/s13073-018-0552-3.
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Beck, S;
Berner, AM;
Bignell, G;
Bond, M;
Callanan, MJ;
Chervova, O;
Conde, L;
... Wood, JN; + view all
(2018)
Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine.
BMC Medical Genomics
, 11
, Article 108. 10.1186/s12920-018-0423-1.
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Bell, CG;
Finer, S;
Lindgren, CM;
Wilson, GA;
Rakyan, VK;
Teschendorff, AE;
Akan, P;
... Int Type 2 Diabet 1q Consortium; + view all
(2010)
Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus.
PLOS ONE
, 5
(11)
, Article e14040. 10.1371/journal.pone.0014040.
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Bell, CG;
Lowe, R;
Adams, PD;
Baccarelli, AA;
Beck, S;
Bell, JT;
Christensen, BC;
... Rakyan, VK; + view all
(2019)
DNA methylation aging clocks: challenges and recommendations.
Genome Biology
, 20
, Article 249. 10.1186/s13059-019-1824-y.
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Bell, CG;
Teschendorff, AE;
Rakyan, VK;
Maxwell, AP;
Beck, S;
Savage, DA;
(2010)
Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus.
BMC Medical Genomics
, 3
, Article 33. 10.1186/1755-8794-3-33.
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Bell, CG;
Wilson, GA;
Beck, S;
(2014)
Human-specific CpG 'beacons' identify human-specific prefrontal cortex H3K4me3 chromatin peaks.
Epigenomics
, 6
(1)
21 - 31.
10.2217/epi.13.74.
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Bell, CG;
Wilson, GA;
Butcher, LM;
Roos, C;
Walter, L;
Beck, S;
(2012)
Human-specific CpG "beacons" identify loci associated with human-specific traits and disease.
Epigenetics
, 7
(10)
1188 - 1199.
10.4161/epi.22127.
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Beltran, M;
Tavares, M;
Justin, N;
Khandelwal, G;
Ambrose, J;
Foster, BM;
Worlock, KB;
... Jenner, RG; + view all
(2019)
G-tract RNA removes Polycomb repressive complex 2 from genes.
Nature Structural & Molecular Biology
, 26
pp. 899-909.
10.1038/s41594-019-0293-z.
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Beltran, M;
Yates, CM;
Skalska, L;
Dawson, M;
Reis, FP;
Viiri, K;
Fisher, CL;
... Jenner, RG; + view all
(2016)
The interaction of PRC2 with RNA or chromatin is mutually antagonistic.
Genome Research
, 26
(7)
pp. 896-907.
10.1101/gr.197632.115.
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Bentham, R;
Litchfield, K;
Watkins, TBK;
Lim, EL;
Rosenthal, R;
Martinez-Ruiz, C;
Hiley, CT;
... McGranahan, N; + view all
(2021)
Using DNA sequencing data to quantify T cell fraction and therapy response.
Nature
, 597
pp. 555-560.
10.1038/s41586-021-03894-5.
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Bernatsky, S;
Velásquez García, HA;
Spinelli, JJ;
Gaffney, P;
Smedby, KE;
Ramsey-Goldman, R;
Wang, SS;
... Clarke, AE; + view all
(2017)
Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma.
Lupus Sci Med
, 4
(1)
, Article e000187. 10.1136/lupus-2016-000187.
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Berndt, Sonja I;
Vijai, Joseph;
Benavente, Yolanda;
Camp, Nicola J;
Nieters, Alexandra;
Wang, Zhaoming;
Smedby, Karin E;
... Rothman, Nathaniel; + view all
(2022)
Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
Leukemia
, 36
(12)
pp. 2835-2844.
10.1038/s41375-022-01711-0.
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Berry, V;
Ionides, A;
Pontikos, N;
Moghul, I;
Moore, AT;
Quinlan, RA;
Michaelides, M;
(2020)
Whole Exome Sequencing Reveals Novel and Recurrent Disease-Causing Variants in Lens Specific Gap Junctional Protein Encoding Genes Causing Congenital Cataract.
Genes
, 11
(5)
, Article 512. 10.3390/genes11050512.
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Berry, V;
Ionides, ACW;
Pontikos, N;
Moghul, I;
Moore, AT;
Cheetham, ME;
Michaelides, M;
(2018)
Whole-genome sequencing reveals a recurrent missense mutation in the Connexin 46 (GJA3) gene causing autosomal-dominant lamellar cataract.
Eye
, 32
pp. 1661-1668.
10.1038/s41433-018-0154-8.
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Bertaux, F;
von Kugelgen, J;
Marguerat, S;
Shahrezaei, V;
(2020)
A bacterial size law revealed by a coarse-grained model of cell physiology.
PLOS Computational Biology
, 16
(9)
10.1371/journal.pcbi.1008245.
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Bertaux, François;
Kleijn, Istvan T;
Marguerat, Samuel;
Shahrezaei, Vahid;
(2023)
Fission yeast obeys a linear size law under nutrient titration.
microPublication Biology
, 2023
10.17912/micropub.biology.000833.
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Bindreither, D;
Ecker, S;
Gschirr, B;
Kofler, A;
Kofler, R;
Rainer, J;
(2014)
The synthetic glucocorticoids prednisolone and dexamethasone regulate the same genes in acute lymphoblastic leukemia cells.
BMC Genomics
, 15
, Article 662. 10.1186/1471-2164-15-662.
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Biswas, D;
Birkbak, NJ;
Rosenthal, R;
Hiley, CT;
Lim, EL;
Papp, K;
Boeing, S;
... TRACERx Consortium; + view all
(2019)
A clonal expression biomarker associates with lung cancer mortality.
Nature Medicine
, 25
pp. 1540-1548.
10.1038/s41591-019-0595-z.
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Bitton, DA;
Atkinson, SR;
Rallis, C;
Smith, GC;
Ellis, DA;
Chen, Y;
Malecki, M;
... Bahler, J; + view all
(2015)
Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast.
Genome Research
, 25
(6)
pp. 884-896.
10.1101/gr.185371.114.
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Bitton, DA;
Rallis, C;
Jeffares, DC;
Smith, GC;
Chen, YY;
Codlin, S;
Marguerat, S;
(2014)
LaSSO, a strategy for genome-wide mapping of intronic lariats and branch-points using RNA-seq.
Genome Res
, 24
pp. 1169-1179.
10.1101/gr.166819.113.
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Bock, C;
Halbritter, F;
Carmona, FJ;
Tierling, S;
Datlinger, P;
Assenov, Y;
Berdasco, M;
... Zhang, K; + view all
(2016)
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications.
NATURE BIOTECHNOLOGY
, 34
(7)
pp. 726-737.
10.1038/nbt.3605.
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Boege, Y;
Malehmir, M;
Healy, ME;
Bettermann, K;
Lorentzen, A;
Vucur, M;
Ahuja, AK;
... Weber, A; + view all
(2017)
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development.
Cancer Cell
, 32
(3)
pp. 342-359.
10.1016/j.ccell.2017.08.010.
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Böiers, C;
Richardson, SE;
Laycock, E;
Zriwil, A;
Turati, VA;
Brown, J;
Wray, JP;
... Enver, T; + view all
(2018)
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Developmental Cell
, 44
(3)
pp. 362-377.
10.1016/j.devcel.2017.12.005.
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Bolik, J;
Krause, F;
Stevanovic, M;
Gandraß, M;
Thomsen, I;
Schacht, S-S;
Rieser, E;
... Schmidt-Arras, D; + view all
(2022)
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
J Exp Med
, 219
(1)
, Article e20201039. 10.1084/jem.20201039.
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|
|
Boned Del Río, I;
Young, LC;
Sari, S;
Jones, GG;
Ringham-Terry, B;
Hartig, N;
Rejnowicz, E;
... Rodriguez-Viciana, P; + view all
(2019)
SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics.
Proceedings of the National Academy of Sciences of the United States of America
10.1073/pnas.1902658116.
(In press).
|
|
|
Boned del Río, Isabel;
(2019)
Therapeutic potential of SHOC2 via its selective contribution of the ERK pathway activation.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Bonsor, Daniel A;
Alexander, Patrick;
Snead, Kelly;
Hartig, Nicole;
Drew, Matthew;
Messing, Simon;
Finci, Lorenzo I;
... Simanshu, Dhirendra K; + view all
(2022)
Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nature Structural and Molecular Biology
, 29
(10)
pp. 966-977.
10.1038/s41594-022-00841-4.
|
|
Boto, C;
Quartin, E;
Cai, Y;
Martin-Lorenzo, A;
Garcia Cenador, MB;
Pinto, S;
Gupta, R;
... Ferreira, L; + view all
(2017)
Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation.
Nature Communications
, 8
, Article 15204. 10.1038/ncomms15204.
|
|
Bouwman, RD;
Palser, A;
Parry, CM;
Coulter, E;
Rasaiyaah, J;
Kellam, P;
Jenner, RG;
(2014)
Human immunodeficiency virus Tat associates with a specific set of cellular RNAs.
Retrovirology
, 11
(1)
, Article 53. 10.1186/1742-4690-11-53.
|
|
|
Breeze, CE;
Beck, S;
Berndt, SI;
Franceschini, N;
(2022)
The missing diversity in human epigenomic studies.
Nature Genetics
, 54
pp. 737-739.
10.1038/s41588-022-01081-4.
|
|
Breeze, CE;
Haugen, E;
Reynolds, A;
Teschendorff, A;
van Dongen, J;
Lan, Q;
Rothman, N;
... Berndt, SI; + view all
(2022)
Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations.
Genome Biololgy
, 23
(1)
, Article 13. 10.1186/s13059-021-02560-3.
|
|
|
Breeze, Charles E;
Haugen, Eric;
Gutierrez-Arcelus, María;
Yao, Xiaozheng;
Teschendorff, Andrew;
Beck, Stephan;
Dunham, Ian;
... Berndt, Sonja I; + view all
(2024)
FORGEdb: a tool for identifying candidate functional variants and uncovering target genes and mechanisms for complex diseases.
Genome Biology
, 25
(1)
, Article 3. 10.1186/s13059-023-03126-1.
|
|
Breeze, Charles E;
Wong, Jason YY;
Beck, Stephan;
Berndt, Sonja I;
Franceschini, Nora;
(2022)
Diversity in EWAS: current state, challenges, and solutions.
Genome Medicine
, 14
, Article 71. 10.1186/s13073-022-01065-3.
|
|
|
Breeze, CE;
Batorsky, A;
Lee, MK;
Szeto, MD;
Xu, X;
McCartney, DL;
Jiang, R;
... Franceschini, N; + view all
(2021)
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
Genome Medicine
, 13
(1)
, Article 74. 10.1186/s13073-021-00877-z.
|
|
|
Breeze, CE;
Paul, DS;
van Dongen, J;
Butcher, LM;
Ambrose, JC;
Barrett, JE;
Lowe, R;
... Beck, S; + view all
(2016)
eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data.
Cell Reports
, 17
(8)
pp. 2137-2150.
10.1016/j.celrep.2016.10.059.
|
|
|
Breeze, CE;
Reynolds, AP;
van Dongen, J;
Dunham, I;
Lazar, J;
Neph, S;
Vierstra, J;
... Beck, S; + view all
(2019)
eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data.
Bioinformatics
10.1093/bioinformatics/btz456.
(In press).
|
|
|
Breeze, Charles E;
(2017)
Epigenetics of complex traits and diseases.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Brian, Duncan Langley;
(2023)
Targeting acute myeloid leukaemia by manipulation of retinoic acid receptor and C-terminal binding protein activity.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Brickman, JM;
Clements, M;
Tyrell, R;
McNay, D;
Woods, K;
Warner, J;
Stewart, A;
... Dattani, M; + view all
(2001)
Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders.
DEVELOPMENT
, 128
(24)
5189 - 5199.
|
|
|
Brooks, Lucy J;
Clements, Melanie P;
Burden, Jemima J;
Kocher, Daniela;
Richards, Luca;
Devesa, Sara Castro;
Zakka, Leila;
... Parrinello, Simona; + view all
(2022)
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 13
(1)
, Article 2163. 10.1038/s41467-022-29916-y.
|
|
Brooks, Lucy J;
Simpson Ragdale, Holly;
Hill, Ciaran Scott;
Clements, Melanie;
Parrinello, Simona;
(2022)
Injury programs shape glioblastoma.
Trends in Neurosciences
10.1016/j.tins.2022.08.006.
(In press).
|
|
Brooks, L;
Viardot, A;
Tsakmaki, A;
Stolarczyk, E;
Howard, JK;
Cani, PD;
Everard, A;
... Bewick, GA; + view all
(2017)
Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety.
Molecular Metabolism
, 6
(1)
pp. 48-60.
10.1016/j.molmet.2016.10.011.
|
|
|
Brooks, LJ;
Clements, MP;
Burden, JJ;
Kocher, D;
Richards, L;
Devesa, SC;
Zakka, L;
... Parrinello, S; + view all
(2021)
The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 12
, Article 2184. 10.1038/s41467-021-22225-w.
|
|
|
Brooks, LJ;
Parrinello, S;
(2017)
Vascular regulation of glioma stem-like cells: a balancing act.
Current Opinion in Neurobiology
, 47
pp. 8-15.
10.1016/j.conb.2017.06.008.
|
|
|
Budin-Ljøsne, I;
Teare, HJ;
Kaye, J;
Beck, S;
Bentzen, HB;
Caenazzo, L;
Collett, C;
... Mascalzoni, D; + view all
(2017)
Dynamic Consent: a potential solution to some of the challenges of modern biomedical research.
BMC Medical Ethics
, 18
, Article 4. 10.1186/s12910-016-0162-9.
|
|
|
Butcher, LM;
Beck, S;
(2017)
Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations.
Methods in Molecular Biology: Population Epigenetics
, 1589
pp. 115-138.
10.1007/7651_2015_259.
|
|
|
Butcher, LM;
Beck, S;
(2015)
Probe Lasso: a novel method to rope in differentially methylated regions with 450K DNA methylation data.
Methods
, 72
21 - 28.
10.1016/j.ymeth.2014.10.036.
|
 |
|
Butcher, LM;
Ito, M;
Brimpari, M;
Morris, TJ;
Soares, FA;
Ährlund-Richter, L;
Carey, N;
... Beck, S; + view all
(2016)
Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells.
Nature Communications
, 7
, Article 10458. 10.1038/ncomms10458.
|
|
C
|
Cantley, J;
Selman, C;
Shukla, D;
Abramov, AY;
Forstreuter, F;
Esteban, MA;
Claret, M;
... Withers, DJ; + view all
(2009)
Deletion of the von Hippel–Lindau gene in pancreatic β cells impairs glucose homeostasis in mice.
Journal of Clinical Investigation
, 119
(1)
pp. 125-135.
10.1172/JCI26934.
|
|
Carbone, L;
Harris, RA;
Gnerre, S;
Veeramah, KR;
Lorente-Galdos, B;
Huddleston, J;
Meyer, TJ;
... Gibbs, RA; + view all
(2014)
Gibbon genome and the fast karyotype evolution of small apes.
Nature
, 513
(7517)
pp. 195-201.
10.1038/nature13679.
|
|
Cardenas, Andres;
Ecker, Simone;
Fadadu, Raj P;
Huen, Karen;
Orozco, Allan;
McEwen, Lisa M;
Engelbrecht, Hannah-Ruth;
... Rehkopf, David H; + view all
(2022)
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults.
Scientific Reports
, 12
, Article 4277. 10.1038/s41598-022-08160-w.
|
|
|
Carters, R;
Cheraghchi-Bashi, A;
Westhorpe, A;
Yu, S;
Shanneik, Y;
Seraia, E;
Ouaret, D;
... Sharma, RA; + view all
(2019)
Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer.
Cancer Biology & Medicine
, 16
(2)
pp. 234-246.
10.20892/j.issn.2095-3941.2018.0284.
|
|
|
Cattin, AL;
Burden, JJ;
Van Emmenis, L;
Mackenzie, FE;
Hoving, JJ;
Garcia Calavia, N;
Guo, Y;
... Lloyd, AC; + view all
(2015)
Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves.
Cell
, 162
(5)
pp. 1127-1139.
10.1016/j.cell.2015.07.021.
|
|
|
Chakravarthy, Ankur;
Reddin, Ian;
Henderson, Stephen;
Dong, Cindy;
Kirkwood, Nerissa;
Jeyakumar, Maxmilan;
Rodriguez, Daniela Rothschild;
... Fenton, Tim R; + view all
(2022)
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Nature Communications
, 13
, Article 5818. 10.1038/s41467-022-33544-x.
|
|
Chakravarthy, A;
Henderson, S;
Fenton, T;
(2014)
When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer.
Molecular & Cellular Oncology
, 1
(1)
e29914 - e29914.
10.4161/mco.29914.
|
|
|
Chakravarthy, A;
Henderson, S;
Thirdborough, SM;
Ottensmeier, CH;
Su, X;
Lechner, M;
Feber, A;
... Fenton, TR; + view all
(2016)
Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.
Journal Of Clinical Oncology
, 34
(34)
pp. 4132-4141.
10.1200/JCO.2016.68.2955.
|
|
|
Chang, J-M;
Floden, EW;
Herrero, J;
Gascuel, O;
Di Tommaso, P;
Notredame, C;
(2019)
Incorporating alignment uncertainty into Felsenstein’s phylogenetic bootstrap to improve its reliability.
Bioinformatics
10.1093/bioinformatics/btz082.
(In press).
|
|
Chapman, MA;
Sive, J;
Ambrose, J;
Roddie, C;
Counsell, N;
Lach, A;
Abbasian, M;
... Yong, K; + view all
(2018)
RNA-Seq of newly diagnosed patients in the PADIMAC study leads to a bortezomib/lenalidomide decision signature.
Blood
, 132
(20)
pp. 2154-2165.
10.1182/blood-2018-05-849893.
|
|
Charlton, J;
Williams, RD;
Weeks, M;
Sebire, NJ;
Popov, S;
Vujanic, G;
Mifsud, W;
... Pritchard-Jones, K; + view all
(2014)
Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood.
Genome Biology
, 15
, Article 434. 10.1186/s13059-014-0434-y.
|
|
Chen, Kezhong;
Kang, Guannan;
Zhang, Zhihong;
Lizaso, Analyn;
Beck, Stephan;
Lyskjær, Iben;
Chervova, Olga;
... Wang, Jun; + view all
(2023)
Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer.
BMC Medicine
, 21
, Article 255. 10.1186/s12916-023-02954-z.
|
|
Chen, Kezhong;
Yang, Fan;
Shen, Haifeng;
Wang, Chenyang;
Li, Xi;
Chervova, Olga;
Wu, Shuailai;
... Wang, Jun; + view all
(2023)
Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer.
Cancer Cell
, 41
(10)
1749-1762.e6.
10.1016/j.ccell.2023.08.010.
|
|
Chen, Yu-Guang;
Rieser, Eva;
Bhamra, Amandeep;
Surinova, Silvia;
Kreuzaler, Peter;
Ho, Meng-Hsing;
Tsai, Wen-Chiuan;
... Walczak, Henning; + view all
(2024)
LUBAC enables tumor-promoting LTβ receptor signaling by
activating canonical NF-κB.
Cell Death & Differentiation
, 31
(10)
pp. 1267-1284.
10.1038/s41418-024-01355-w.
|
|
Chen, L;
Ge, B;
Casale, FP;
Vasquez, L;
Kwan, T;
Garrido-Martín, D;
Watt, S;
... Soranzo, N; + view all
(2016)
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.
Cell
, 167
(5)
1398-1414.e24.
10.1016/j.cell.2016.10.026.
|
|
Chen, W;
Morabito, SJ;
Kessenbrock, K;
Enver, T;
Meyer, KB;
Teschendorff, AE;
(2019)
Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome.
Communications Biology
, 2
, Article 306. 10.1038/s42003-019-0554-8.
|
|
|
Chen, Y;
Breeze, CE;
Zhen, S;
Beck, S;
Teschendorff, AE;
(2016)
Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer.
Epigenetics & Chromatin
, 9
, Article 10. 10.1186/s13072-016-0058-4.
|
|
|
Chervova, Olga;
Chernysheva, Elizabeth;
Panteleeva, Kseniia;
Widayati, Tyas Arum;
Hrbkova, Natalie;
Schneider, Jadesada;
Maximov, Vladimir;
... Beck, Stephan; + view all
(2022)
Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort.
Biology
, 12
(1)
, Article 68. 10.3390/biology12010068.
|
|
Chervova, O;
(2012)
The massless Dirac equation from the continuum mechanics and microlocal analysis perspectives.
Doctoral thesis , UCL (University College London).
|
|
|
Chervova, O;
Conde, L;
Guerra-Assunção, JA;
Moghul, I;
Webster, AP;
Berner, A;
Larose Cadieux, E;
... Beck, S; + view all
(2019)
The Personal Genome Project-UK, an open access resource of human multi-omics data.
Scientific Data
, 6
, Article 257. 10.1038/s41597-019-0205-4.
|
|
|
Chervova, O;
Oksanen, L;
(2016)
Time reversal method with stabilizing boundary conditions for Photoacoustic tomography.
Inverse Problems
, 32
(12)
, Article 125004. 10.1088/0266-5611/32/12/125004.
|
|
Cheung, WA;
Shao, X;
Morin, A;
Siroux, V;
Kwan, T;
Ge, B;
Aissi, D;
... Grundberg, E; + view all
(2017)
Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.
Genome Biology
, 18
, Article 50. 10.1186/s13059-017-1173-7.
|
|
|
Chhetri, JB;
Drousioti, E;
Guerra-Assunção, JA;
Herrero, J;
Ooi, SKT;
(2018)
Generation of a Cancer Testis Antigen Mcherry Reporter Hct116 Colorectal Carcinoma Cell Line.
Heliyon
, 4
(10)
, Article e00858. 10.1016/j.heliyon.2018.e00858.
|
|
|
Chia, Kim Hou;
Takaki, Hiroko;
Fujimitsu, Kazuyuki;
Darling, Sarah;
Zou, Juan;
Rappsilber, Juri;
Yamano, Hiroyuki;
(2024)
CDK1-PP2A-B55 interplay ensures cell cycle oscillation via Apc1-loop300.
Cell Reports
, 43
(5)
, Article 114155. 10.1016/j.celrep.2024.114155.
|
|
|
Chia, KH;
Fukuda, T;
Sofyantoro, F;
Matsuda, T;
Amai, T;
Shiozaki, K;
(2018)
Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases.
eLife
, 6
, Article e30880. 10.7554/eLife.30880.
|
|
|
Chickarmane, V;
Enver, T;
Peterson, C;
(2009)
Computational Modeling of the Hematopoietic Erythroid-Myeloid Switch Reveals Insights into Cooperativity, Priming, and Irreversibility.
PLOS COMPUT BIOL
, 5
(1)
, Article e1000268. 10.1371/journal.pcbi.1000268.
|
|
|
Childs, A;
Steele, CD;
Vesely, C;
Rizzo, FMM;
Ensell, L;
Lowe, H;
Dhami, P;
... Meyer, T; + view all
(2021)
Whole genome sequencing of single circulating tumor cells from neuroendocrine neoplasms.
Endocrine-Related Cancer
10.1530/ERC-21-0179.
(In press).
|
|
|
Choudhury, AI;
Heffron, H;
Smith, MA;
Al-Qassab, H;
Xu, AW;
Selman, C;
Simmgen, M;
... Withers, DJ; + view all
(2005)
The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
J CLIN INVEST
, 115
(4)
940 - 950.
|
|
|
Church, DM;
Schneider, VA;
Steinberg, K;
Schatz, MC;
Quinlan, AR;
Chin, C-S;
Kitts, PA;
... Flicek, P; + view all
(2015)
Extending reference assembly models.
Genome Biology
, 16
(1)
, Article 13. 10.1186/s13059-015-0587-3.
|
|
|
Claret, M;
Smith, MA;
Batterham, RL;
Selman, C;
Choudhury, AI;
Fryer, LGD;
Clements, M;
... Withers, DJ; + view all
(2007)
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
J CLIN INVEST
, 117
(8)
2325 - 2336.
10.1172/JCI31516.
|
|
|
Clements, Melanie;
Simpson Ragdale, Holly;
Garcia-Diaz, Claudia;
Parrinello, Simona;
(2024)
Generation of immunocompetent somatic glioblastoma mouse models through in situ transformation of subventricular zone neural stem cells.
STAR Protocols
, 5
(1)
, Article 102928. 10.1016/j.xpro.2024.102928.
|
|
Clements, Melanie;
Tang, Wenhao;
Florjanic Baronik, Zan;
Simpson Ragdale, Holly;
Oria, Roger;
Volteras, Dimitrios;
White, Ian J;
... Parrinello, Simona; + view all
(2025)
Axonal injury is a targetable driver of glioblastoma progression.
Nature
, 646
pp. 452-461.
10.1038/s41586-025-09411-2.
|
|
Clements, M;
Brickman, JM;
Jones, CM;
Clements, M;
Smith, JC;
Beddington, RS;
(2000)
Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function.
Development
, 127
(11)
pp. 2303-2315.
|
|
|
Clements, M;
Pernaute, B;
Vella, F;
Rodriguez, TA;
(2011)
Crosstalk between Nodal/Activin and MAPK p38 Signaling Is Essential for Anterior-Posterior Axis Specification.
Current Biology
, 21
(15)
pp. 1289-1295.
10.1016/j.cub.2011.06.048.
|
|
|
Clements, MP;
Byrne, E;
Camarillo Guerrero, LF;
Cattin, A-L;
Zakka, L;
Ashraf, A;
Burden, JJ;
... Parrinello, S; + view all
(2017)
The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration.
Neuron
, 96
(1)
98-114.e7.
10.1016/j.neuron.2017.09.008.
|
|
|
Cobb, BS;
Hertweck, A;
Smith, J;
O'Connor, E;
Graf, D;
Cook, T;
Smale, ST;
... Merkenschlager, M; + view all
(2006)
A role for Dicer in immune regulation.
Journal of Experimental Medicine
, 203
(11)
pp. 2519-2527.
10.1084/jem.20061692.
|
|
|
Collopy, LC;
Ware, TL;
Goncalves, T;
Í Kongsstovu, S;
Yang, Q;
Amelina, H;
Pinder, C;
... Tomita, K; + view all
(2018)
LARP7 family proteins have conserved function in telomerase assembly.
Nature Communications
, 9
(1)
, Article 557. 10.1038/s41467-017-02296-4.
|
|
|
Conesa, A;
Beck, S;
(2019)
Making multi-omics data accessible to researchers.
[Editorial comment].
Scientific Data
, 6
(1)
, Article 251. 10.1038/s41597-019-0258-4.
|
|
|
Cook, R;
Zoumpoulidou, G;
Luczynski, MT;
Rieger, S;
Moquet, J;
Spanswick, VJ;
Hartley, JA;
... Mittnacht, S; + view all
(2015)
Direct Involvement of Retinoblastoma Family Proteins in DNA Repair by Non-homologous End-Joining.
Cell Rep
, 10
(12)
2006 - 2018.
10.1016/j.celrep.2015.02.059.
|
|
|
Coppe, JP;
Patil, CK;
Rodier, F;
Krtolica, A;
Beausejour, CM;
Parrinello, S;
Hodgson, JG;
... Campisi, J; + view all
(2010)
A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen.
PLOS ONE
, 5
(2)
, Article e9188. 10.1371/journal.pone.0009188.
|
|
|
Corpas, M;
Beck, S;
Glusman, G;
Shabani, M;
(2021)
Editorial: Personal Genomes: Accessing, Sharing, and Interpretation.
Frontiers in Genetics
, 12
, Article 687584. 10.3389/fgene.2021.687584.
|
|
|
Cortés, E;
Huidobro, PA;
Sinclair, HG;
Guldbrand, S;
Peveler, WJ;
Davies, T;
Parrinello, S;
... Maier, SA; + view all
(2016)
Plasmonic Nanoprobes for Stimulated Emission Depletion Nanoscopy.
ACS Nano
, 10
(11)
pp. 10454-10461.
10.1021/acsnano.6b06361.
|
|
Cortese, R;
Lewin, J;
Backdahl, L;
Krispin, M;
Wasserkort, R;
Eckhardt, F;
Beck, S;
(2011)
Genome-Wide Screen for Differential DNA Methylation Associated with Neural Cell Differentiation in Mouse.
PLOS ONE
, 6
(10)
, Article e26002. 10.1371/journal.pone.0026002.
|
|
|
Cottone, Lucia;
Ligammari, Lorena;
Lee, Hang-Mao;
Knowles, Helen J;
Henderson, Stephen;
Bianco, Sara;
Davies, Christopher;
... Flanagan, Adrienne M; + view all
(2022)
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cell Death & Differentiation
, 29
pp. 2459-2471.
10.1038/s41418-022-01031-x.
|
|
Cottone, L;
Cribbs, AP;
Khandelwal, G;
Wells, G;
Ligammari, L;
Philpott, M;
Tumber, A;
... Flanagan, AM; + view all
(2020)
Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.
Cancer Research
, 80
(20)
pp. 4540-4551.
10.1158/0008-5472.CAN-20-1387.
|
|
Croucher, NJ;
Fookes, MC;
Perkins, TT;
Turner, DJ;
Marguerat, SB;
Keane, T;
Quail, MA;
... Thomson, NR; + view all
(2009)
A simple method for directional transcriptome sequencing using Illumina technology.
Nucleic Acids Research
, 37
(22)
, Article e148. 10.1093/nar/gkp811.
|
|
|
Cui, S;
McGranahan, N;
Gao, J;
Chen, P;
Jiang, W;
Yang, L;
Ma, L;
... Wu, S; + view all
(2023)
Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing.
Nature Communications
, 14
(1)
, Article 892. 10.1038/s41467-023-36558-1.
|
D
|
Danovi, D;
Cremona, CA;
Machado-da-Silva, G;
Basu, S;
Noon, LA;
Parrinello, S;
Lloyd, AC;
(2010)
A Genetic Screen for Anchorage-Independent Proliferation in Mammalian Cells Identifies a Membrane-Bound Neuregulin.
PLOS ONE
, 5
(7)
, Article e11774. 10.1371/journal.pone.0011774.
|
|
|
das Neves, RP;
Jones, NS;
Andreu, L;
Gupta, R;
Enver, T;
Iborra, FJ;
(2010)
Connecting Variability in Global Transcription Rate to Mitochondrial Variability.
PLoS Biology
, 8
(12)
, Article e1000560. 10.1371/journal.pbio.1000560.
|
|
|
Dawes, JC;
Webster, P;
Iadarola, B;
Garcia-Diaz, C;
Dore, M;
Bolt, BJ;
Dewchand, H;
... Uren, AG; + view all
(2020)
LUMI-PCR: an Illumina platform ligation-mediated PCR protocol for integration site cloning, provides molecular quantitation of integration sites.
Mobile DNA
, 11
, Article 7. 10.1186/s13100-020-0201-4.
|
|
|
de la Rosa, R;
Steinmaus, C;
Akers, NK;
Conde, L;
Ferreccio, C;
Kalman, D;
Zhang, KR;
... Smith, MT; + view all
(2017)
Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population.
Environmental and Molecular Mutagenesis
, 58
(6)
pp. 411-422.
10.1002/em.22104.
|
|
|
Denas, O;
Sandstrom, R;
Cheng, Y;
Beal, K;
Herrero, J;
Hardison, RC;
Taylor, J;
(2015)
Genome-wide comparative analysis reveals human-mouse regulatory landscape and evolution.
BMC Genomics
, 16
, Article 87. 10.1186/s12864-015-1245-6.
|
|
|
Dennis, MY;
Paracchini, S;
Scerri, TS;
Prokunina-Olsson, L;
Knight, JC;
Wade-Martins, R;
Coggill, P;
... Monaco, AP; + view all
(2009)
A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene.
PLOS GENET
, 5
(3)
, Article e1000436. 10.1371/journal.pgen.1000436.
|
|
|
Di Benedetto, Carolina;
Khan, Taimoor;
Serrano-Saenz, Santiago;
Rodriguez-Lemus, Anthony;
Klomsiri, Chananat;
Beutel, Tim-Mathis;
Thach, Alysia;
... Betancur, Paola; + view all
(2023)
Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis.
Cancers
, 15
(3)
, Article 967. 10.3390/cancers15030967.
|
|
Dieck, S;
Ibarra, M;
Moghul, I;
Yeung, MW;
Pantel, JT;
Thiele, S;
Pfau, M;
... Krawitz, PM; + view all
(2020)
Factors in color fundus photographs that can be used by humans to determine sex of individuals.
Translational Vision Science and Technology
, 9
(7)
, Article 8. 10.1167/tvst.9.7.8.
|
|
|
Diot, A;
Agnew, T;
Sanderson, J;
Liao, C;
Carver, J;
Neves, RPD;
Gupta, R;
... Poulton, J; + view all
(2018)
Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation.
Frontiers in Cell and Developmental Biology
, 6
, Article 103. 10.3389/fcell.2018.00103.
|
|
|
Dixon, JR;
Xu, J;
Dileep, V;
Zhan, Y;
Songs, F;
Le, VT;
Yardimci, GA;
... Yue, F; + view all
(2018)
Integrative detection and analysis of structural variation in cancer genomes.
Nature Genetics
, 50
pp. 1388-1398.
10.1038/s41588-018-0195-8.
|
|
Docherty, SJ;
Butcher, LM;
Schalkwyk, LC;
Plomin, R;
(2007)
Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies.
BMC Genomics
, 8
, Article 214. 10.1186/1471-2164-8-214.
|
|
|
Dondelinger, Y;
Darding, M;
Bertrand, MJ;
Walczak, H;
(2016)
Poly-ubiquitination in TNFR1-mediated necroptosis.
Cellular Molecular Life Sciences
, 73
(11)
pp. 2165-2176.
10.1007/s00018-016-2191-4.
|
|
|
Downes, RJ;
Vassiliev, D;
(2016)
Spectral theoretic characterization of the massless Dirac action.
Mathematika
, 62
pp. 701-718.
10.1112/S0025579315000509.
|
|
|
Dritsoula, A;
Kislikova, M;
Oomatia, A;
Webster, AP;
Beck, S;
Ponticos, M;
Lindsey, B;
... Caplin, B; + view all
(2021)
Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology.
Epigenetics
, 16
(7)
pp. 718-728.
10.1080/15592294.2020.1819666.
|
|
Dunwoodie, S;
Clements, M;
Sparrow, DB;
Sa, X;
Conlon, RA;
Beddington, RS;
(2002)
Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.
Development
, 129
(7)
pp. 1795-1806.
|
|
|
Dupras, Charles;
Knoppers, Terese;
Palmour, Nicole;
Beauchamp, Elisabeth;
Liosi, Stamatina;
Siebert, Reiner;
Berner, Alison May;
... Joly, Yann; + view all
(2022)
Researcher perspectives on ethics considerations in epigenetics: an international survey.
Clinical Epigenetics
, 14
(1)
, Article 110. 10.1186/s13148-022-01322-7.
|
|
Dyke, SOM;
Linden, M;
Lappalainen, I;
De Argila, JR;
Carey, K;
Lloyd, D;
Spalding, JD;
... Flicek, P; + view all
(2018)
Registered access: authorizing data access.
European Journal of Human Genetics
, 26
pp. 1721-1731.
10.1038/s41431-018-0219-y.
|
|
Dyke, SOM;
Saulnier, KM;
Dupras, C;
Webster, AP;
Maschke, K;
Rothstein, M;
Siebert, R;
... Joly, Y; + view all
(2019)
Points-to-consider on the return of results in epigenetic research.
Genome Medicine
, 11
(1)
, Article 31. 10.1186/s13073-019-0646-6.
|
|
E
|
Ebinger, S;
Oezdemir, EZ;
Ziegenhain, C;
Tiedt, S;
Alves, CC;
Grunert, M;
Dworzak, M;
... Jeremias, I; + view all
(2016)
Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.
Cancer Cell
, 30
(6)
pp. 849-862.
10.1016/j.ccell.2016.11.002.
|
|
|
Ecker, S;
Beck, S;
(2019)
The epigenetic clock: a molecular crystal ball for human aging?
Aging (Albany NY)
, 11
(2)
pp. 833-835.
10.18632/aging/101712.
|
|
|
Ecker, S;
Beck, S;
(2017)
Epigenetic variation taking center stage in immunological research.
Epigenomics
, 9
(4)
pp. 375-378.
10.2217/epi-2017-0006.
|
|
Ecker, S;
Chen, L;
Pancaldi, V;
Bagger, FO;
Fernández, JM;
Carrillo de Santa Pau, E;
Juan, D;
... Paul, DS; + view all
(2017)
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Genome Biology
, 18
, Article 18. 10.1186/s13059-017-1156-8.
|
|
|
Ecker, S;
Pancaldi, V;
Rico, D;
Valencia, A;
(2015)
Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia.
Genome Medicine
, 7
, Article 8. 10.1186/s13073-014-0125-z.
|
|
|
Ecker, S;
Pancaldi, V;
Valencia, A;
Beck, S;
Paul, DS;
(2018)
Epigenetic and Transcriptional Variability Shape Phenotypic Plasticity.
BioEssays
, 40
(2)
, Article 1700148. 10.1002/bies.201700148.
|
|
|
Ellis, DA;
Reyes-Martín, F;
Rodríguez-López, M;
Cotobal, C;
Sun, X-M;
Saintain, Q;
Jeffares, DC;
... Bähler, J; + view all
(2021)
R-loops and regulatory changes in chronologically ageing fission yeast cells drive non-random patterns of genome rearrangements.
PLOS Genetics
, 17
(8)
, Article e1009784. 10.1371/journal.pgen.1009784.
|
|
|
Emuss, V;
Lagos, D;
Pizzey, A;
Gratrix, F;
Henderson, SR;
Boshoff, C;
(2009)
KSHV Manipulates Notch Signaling by DLL4 and JAG1 to Alter Cell Cycle Genes in Lymphatic Endothelia.
PLoS Pathogens
, 5
(10)
, Article e1000616. 10.1371/journal.ppat.1000616.
|
|
|
Engelbrecht, Hannah-Ruth;
Merrill, Sarah M;
Gladish, Nicole;
MacIsaac, Julie L;
Lin, David TS;
Ecker, Simone;
Chrysohoou, Christina A;
... Rehkopf, David H; + view all
(2022)
Sex differences in epigenetic age in Mediterranean high longevity regions.
Frontiers in Aging
, 3
, Article 1007098. 10.3389/fragi.2022.1007098.
|
|
Enriquez-Gasca, Rocio;
Gould, Poppy A;
Tunbak, Hale;
Conde, Lucia;
Herrero, Javier;
Chittka, Alexandra;
Beck, Christine R;
... Rowe, Helen M; + view all
(2023)
Co-option of endogenous retroviruses through genetic escape from TRIM28 repression.
Cell Reports
, 42
(6)
, Article 112625. 10.1016/j.celrep.2023.112625.
|
|
|
Evans, CM;
Jenner, RG;
(2013)
Transcription factor interplay in T helper cell differentiation.
Briefings in Functional Genomics
, 12
(6)
pp. 499-511.
10.1093/bfgp/elt025.
|
|
F
|
Fanale, D;
Amodeo, V;
Caruso, S;
(2017)
The Interplay between Metabolism, PPAR Signaling Pathway, and Cancer.
PPAR Research
, 2017
, Article 1830626. 10.1155/2017/1830626.
|
|
|
Fatima, Roshan;
Akhade, Vijay Suresh;
Pal, Debosree;
Rao, Satyanarayana MR;
(2015)
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets.
Molecular and Cellular Therapies
, 3
, Article 5. 10.1186/s40591-015-0042-6.
|
|
|
Feber, A;
Arya, M;
De Winter, P;
Saqib, M;
Nigam, R;
Malone, PR;
Tan, WS;
... Kelly, JD; + view all
(2015)
Epigenetics Markers of Metastasis and HPV-Induced Tumorigenesis in Penile Cancer.
Clinical Cancer Research
, 21
(5)
pp. 1196-1206.
10.1158/1078-0432.CCR-14-1656.
|
|
|
Feber, A;
Dhami, P;
Dong, L;
de Winter, P;
Tan, WS;
Martínez-Fernández, M;
Paul, DS;
... Kelly, JD; + view all
(2017)
UroMark - a urinary biomarker assay for the detection of bladder cancer.
Clinical Epigenetics
, 9
, Article 8. 10.1186/s13148-016-0303-5.
|
|
|
Feber, A;
Guilhamon, P;
Lechner, M;
Fenton, T;
Wilson, GA;
Thirlwell, C;
Morris, TJ;
... Beck, S; + view all
(2014)
Using high-density DNA methylation arrays to profile copy number alterations.
Genome Biol
, 15
(2)
, Article R30. 10.1186/gb-2014-15-2-r30.
|
|
|
Feber, A;
Worth, DC;
Chakravarthy, A;
de Winter, P;
Shah, K;
Arya, M;
Saqib, M;
... Kelly, JD; + view all
(2016)
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.
Cancer Research
, 76
(16)
pp. 4720-4727.
10.1158/0008-5472.CAN-15-3134.
|
|
Fennell, A;
Fernández-Álvarez, A;
Tomita, K;
Cooper, JP;
(2015)
Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation.
Journal of Cell Biology
, 208
(4)
pp. 415-428.
10.1083/jcb.201409058.
|
|
|
Fernandes, Liane P;
Enriquez-Gasca, Rocio;
Gould, Poppy A;
Holt, James H;
Conde, Lucia;
Ecco, Gabriela;
Herrero, Javier;
... Rowe, Helen M; + view all
(2022)
A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819.
Science Advances
, 8
(43)
, Article eabp8085. 10.1126/sciadv.abp8085.
|
|
Ferreira, PG;
Jares, P;
Rico, D;
Gomez-Lopez, G;
Martinez-Trillos, A;
Villamor, N;
Ecker, S;
... Guigo, R; + view all
(2014)
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia.
Genome Research
, 24
(2)
pp. 212-226.
10.1101/gr.152132.112.
|
 |
|
Ferreira, R;
Napoli, J;
Enver, T;
Bernardino, L;
Ferreira, L;
(2020)
Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine.
Nature Communications
, 11
, Article 4265. 10.1038/s41467-020-18042-2.
|
|
|
Ferrer, IR;
West, HC;
Henderson, S;
Ushakov, DS;
Santos E Sousa, P;
Strid, J;
Chakraverty, R;
... Bennett, CL; + view all
(2019)
A wave of monocytes is recruited to replenish the long-term Langerhans cell network after immune injury.
Science Immunology
, 4
(38)
, Article eaax8704. 10.1126/sciimmunol.aax8704.
|
|
|
Flicek, P;
Amode, MR;
Barrell, D;
Beal, K;
Billis, K;
Brent, S;
Carvalho-Silva, D;
... Searle, SMJ; + view all
(2014)
Ensembl 2014.
Nucleic Acids Research
, 42
(D1)
D749-D755.
10.1093/nar/gkt1196.
|
|
|
Frampton, D;
Schwenzer, H;
Marino, G;
Butcher, LM;
Pollara, G;
Kriston-Vizi, J;
Venturini, C;
... Fassati, A; + view all
(2018)
Molecular Signatures of Regression of the Canine Transmissible Venereal Tumor.
Cancer Cell
, 33
(4)
620-633.e6.
10.1016/j.ccell.2018.03.003.
|
|
|
Frankell, Alexander M;
Dietzen, Michelle;
Al Bakir, Maise;
Lim, Emilia L;
Karasaki, Takahiro;
Ward, Sophia;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2024)
The evolution of lung cancer and impact of subclonal selection in TRACERx (vol 616, pg 525, 2023).
[Corrigendum].
Nature
, 631
, Article E15. 10.1038/s41586-024-07738-w.
|
|
|
Frankell, AM;
Dietzen, M;
Al Bakir, M;
Lim, EL;
Karasaki, T;
Ward, S;
Veeriah, S;
... Gilbert, K; + view all
(2023)
The evolution of lung cancer and impact of subclonal selection in TRACERx.
Nature
, 616
pp. 525-533.
10.1038/s41586-023-05783-5.
|
|
Fujimitsu, K;
Grimaldi, M;
Yamano, H;
(2016)
Cyclin dependent kinase 1-dependent activation of APC/C ubiquitin ligase.
Science
, 352
(6289)
pp. 1121-1124.
10.1126/science.aad3925.
|
|
|
Fujimitsu, K;
Yamano, H;
(2021)
Dynamic regulation of mitotic ubiquitin ligase APC/C by coordinated Plx1 kinase and PP2A phosphatase action on a flexible Apc1 loop.
EMBO Journal
, Article ARTN e10. 10.15252/embj.2020107516.
(In press).
|
|
|
Fujimitsu, K;
Yamano, H;
(2019)
PP2A-B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis.
EMBO Reports
, Article e48503. 10.15252/embr.201948503.
(In press).
|
|
|
Funes, JM;
Henderson, S;
Kaufman, R;
Flanagan, JM;
Robson, M;
Pedley, B;
Moncada, S;
(2014)
Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival.
Molecular Cancer
, 13
, Article 20. 10.1186/1476-4598-13-20.
|
|
Furniss, DJ;
Blandford, A;
Mayer, A;
(2011)
Unremarkable errors: low-level disturbances in infusion pump use.
In:
Proceedings of the 25th British Computer Society Conference on Human-Computer Interaction, BCS-HCI 2011, Newcastle Upon Tyne, United Kingdom, 4-8 July 2011.
(pp. pp. 197-204).
BCS: Swindon, UK.
|
|
G
|
Gaizley, Emily;
(2024)
Proteomic characterisation of cellular quiescence in glioblastoma.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Gaizley, Emily J;
Chen, Xiuyuan;
Bhamra, Amandeep;
Enver, Tariq;
Surinova, Silvia;
(2025)
Multiplexed phosphoproteomics of low cell numbers using SPARCE.
Communications Biology
, 8
, Article 666. 10.1038/s42003-025-08068-x.
|
|
|
Gaizley, Emily J;
Surinova, Silvia;
(2025)
The pursuit of ultrasensitive phosphoproteomics to unravel signalling in rare cells.
Communications Biology
10.1038/s42003-025-09131-3.
(In press).
|
|
|
Galleu, A;
Riffo-Vasquez, Y;
Trento, C;
Lomas, C;
Dolcetti, L;
Cheung, TS;
von Bonin, M;
... Dazzi, F; + view all
(2017)
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation.
Science Translational Medicine
, 9
(416)
, Article eaam7828. 10.1126/scitranslmed.aam7828.
|
|
|
Galluzzi, L;
Bravo-San Pedro, JM;
Vitale, I;
Aaronson, SA;
Abrams, JM;
Adam, D;
Alnemri, ES;
... Kroemer, G; + view all
(2015)
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.
Cell Death and Differentiation
, 22
(1)
pp. 58-73.
10.1038/cdd.2014.137.
|
|
Galluzzi, L;
Vitale, I;
Aaronson, SA;
Abrams, JM;
Adam, D;
Agostinis, P;
Alnemri, ES;
... Kroemer, G; + view all
(2018)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Cell Death & Differentiation
10.1038/s41418-017-0012-4.
|
|
|
Galvez-Cancino, Felipe;
Navarrete, Mariela;
Beattie, Gordon;
Puccio, Simone;
Conde-Gallastegi, Enrique;
Foster, Kane;
Morris, Yasmin;
... Quezada, Sergio A; + view all
(2025)
Correction:
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies.
[Corrigendum].
Immunity
, 58
(7)
pp. 1862-1864.
10.1016/j.immuni.2025.05.019.
|
|
Gangoso, E;
Southgate, B;
Bradley, L;
Rus, S;
Galvez-Cancino, F;
McGivern, N;
Güç, E;
... Pollard, SM; + view all
(2021)
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Cell
10.1016/j.cell.2021.03.023.
(In press).
|
|
|
Garcia Diaz, Claudia;
(2022)
Novel de novo Glioblastoma mouse models reveal differences in the biology of the tumour bulk and invasive margin.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Garcia-Diaz, Claudia;
Mereu, Elisabetta;
Clements, Melanie;
Pöysti, Anni;
Galvez-Cancino, Felipe;
Castillo, Simon;
Courtot, Lilas;
... Parrinello, Simona; + view all
(2021)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin.
bioRxiv: Cold Spring Harbor, NY, USA.
|
|
|
Garcia-Diaz, Claudia;
Pöysti, Anni;
Mereu, Elisabetta;
Clements, Melanie P;
Brooks, Lucy J;
Galvez-Cancino, Felipe;
Castillo, Simon P;
... Parrinello, Simona; + view all
(2023)
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Cell Reports
, 42
(5)
, Article 112472. 10.1016/j.celrep.2023.112472.
|
|
|
Gerber, JP;
Russ, J;
Chandrasekar, V;
Offermann, N;
Lee, H-M;
Spear, S;
Guzzi, N;
... Salomoni, P; + view all
(2021)
Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Nature Cell Biology
10.1038/s41556-021-00774-y.
|
|
|
Geron, Ifat;
Savino, Angela Maria;
Fishman, Hila;
Tal, Noa;
Brown, John;
Turati, Virginia A;
James, Chela;
... Izraeli, Shai; + view all
(2022)
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
Nature Communications
, 13
, Article 659. 10.1038/s41467-022-28218-7.
|
|
|
Ghorani, E;
Reading, JL;
Henry, JY;
Massy, MRD;
Rosenthal, R;
Turati, V;
Joshi, K;
... Quezada, SA; + view all
(2020)
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Nature Cancer
, 1
(5)
pp. 546-561.
10.1038/s43018-020-0066-y.
|
|
Giampazolias, E;
Zunino, B;
Dhayade, S;
Bock, F;
Cloix, C;
Cao, K;
Roca, A;
... Tait, SWG; + view all
(2017)
Mitochondrial permeabilization engages NF-kappa B-dependent anti-tumour activity under caspase deficiency.
Nature Cell Biology
, 19
(9)
pp. 1116-1129.
10.1038/ncb3596.
|
|
|
Godfrey, M;
Touati, SA;
Kataria, M;
Jones, A;
Snijders, AP;
Uhlmann, F;
(2017)
PP2A(Cdc55) Phosphatase Imposes Ordered Cell- Cycle Phosphorylation by Opposing Threonine Phosphorylation.
Molecular Cell
, 65
(3)
393-402.e3.
10.1016/j.molcel.2016.12.018.
|
|
|
Goh, G;
Schmid, R;
Guiver, K;
Arpornwirat, W;
Chitapanarux, I;
Ganju, V;
Im, SA;
... Swanton, C; + view all
(2016)
Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine.
PLOS Med
, 13
(12)
, Article e1002136. 10.1371/journal.pmed.1002136.
|
|
Goldberg, R;
Clough, JN;
Roberts, LB;
Sanchez, J;
Kordasti, S;
Petrov, N;
Hertweck, A;
... Lord, GM; + view all
(2021)
A Crohn’s Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling.
Journal of Crohn's and Colitis
, 15
(12)
pp. 2054-2065.
10.1093/ecco-jcc/jjab103.
|
|
|
Goncalves, T;
Zoumpoulidou, G;
Alvarez-Mendoza, C;
Mancusi, C;
Collopy, LC;
Strauss, SJ;
Mittnacht, S;
(2020)
Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors.
ACS Pharmacology & Translational Science
, 3
(6)
pp. 1253-1264.
10.1021/acsptsci.0c00125.
|
|
Gong, Grace Q;
Bilanges, Benoit;
Allsop, Ben;
Masson, Glenn R;
Roberton, Victoria;
Askwith, Trevor;
Oxenford, Sally;
... Vanhaesebroeck, Bart; + view all
(2023)
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Nature
, 618
pp. 159-168.
10.1038/s41586-023-05972-2.
|
|
|
Gravells, P;
Ahrabi, S;
Vangala, RK;
Tomita, K;
Brash, JT;
Brustle, LA;
Chung, C;
... Porter, AC; + view all
(2015)
Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.
Human Molecular Genetics
, 24
(24)
pp. 7097-7110.
10.1093/hmg/ddv409.
|
|
Gravells, P;
Tomita, K;
Booth, A;
Poznansky, J;
Porter, AC;
(2013)
Chemical genetic analyses of quantitative changes in Cdk1 activity during the human cell cycle.
Human Molecular Genetics
, 22
(14)
pp. 2842-2851.
10.1093/hmg/ddt133.
|
|
|
Gripp, KW;
Schill, L;
Schoyer, L;
Stronach, B;
Bennett, AM;
Blaser, S;
Brown, A;
... Ratner, N; + view all
(2020)
The sixth international RASopathies symposium: Precision medicine—From promise to practice.
American Journal of Medical Genetics Part A
, 182
(3)
pp. 597-606.
10.1002/ajmg.a.61434.
|
|
Guerra-Assunção, JA;
Conde, L;
Moghul, I;
Webster, AP;
Ecker, S;
Chervova, O;
Chatzipantsiou, C;
... Herrero, J; + view all
(2020)
GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline.
Frontiers in Genetics
, 11
, Article 518644. 10.3389/fgene.2020.518644.
|
|
|
Guibentif, C;
Ronn, RE;
Boiers, C;
Lang, S;
Saxena, S;
Soneji, S;
Enver, T;
... Woods, N-B; + view all
(2017)
Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition.
Cell Reports
, 19
(1)
pp. 10-19.
10.1016/j.celrep.2017.03.023.
|
|
|
Guilhamon, P;
Butcher, LM;
Presneau, N;
Wilson, GA;
Feber, A;
Paul, DS;
Schütte, M;
... Beck, S; + view all
(2014)
Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics.
Genome Med
, 6
(12)
, Article 116. 10.1186/s13073-014-0116-0.
|
|
|
Guilhamon, P;
Eskandarpour, M;
Halai, D;
Wilson, GA;
Feber, A;
Teschendorff, AE;
Gomez, V;
... Beck, S; + view all
(2013)
Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.
Nature Communications
, 4
, Article 2166. 10.1038/ncomms3166.
|
|
|
Gunnell, A;
Webb, HM;
Wood, CD;
McClellan, MJ;
Wichaidit, B;
Kempkes, B;
Jenner, RG;
... West, MJ; + view all
(2016)
RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth.
Nucleic Acids Research
, 44
(10)
, Article 4636-4650. 10.1093/nar/gkw085.
|
|
|
Guo, L;
Davis, B;
Nizari, S;
Normando, EM;
Shi, H;
Galvao, J;
Turner, L;
... Cordeiro, MF; + view all
(2014)
Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo.
Cell Death Dis
, 5
, Article e1460. 10.1038/cddis.2014.399.
|
|
|
Gupta, R;
Gant, VA;
Williams, B;
Enver, T;
(2020)
Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms.
International Journal of Infectious Diseases
10.1016/j.ijid.2020.08.004.
(In press).
|
|
|
Gupta, R;
Turati, V;
Brian, D;
Thrussel, C;
Wilbourn, B;
May, G;
Enver, T;
(2020)
Nov/CCN3 Enhances Cord Blood Engraftment by Rapidly Recruiting Latent Human Stem Cell Activity.
Cell Stem Cell
10.1016/j.stem.2020.02.012.
(In press).
|
H
|
Haefliger, Simon;
Chervova, Olga;
Davies, Christopher;
Nottley, Steven;
Hargreaves, Steven;
Sumathi, Vaiyapuri P;
Amary, Fernanda;
... Lyskjaer, Iben; + view all
(2023)
Subclassification of epithelioid sarcoma with potential therapeutic impact.
The Journal of Pathology
10.1002/path.6135.
(In press).
|
|
|
Hagan, AE;
Znati, SA;
Carter, R;
Westhorpe, A;
Macfarlane, WM;
Phillips, GJ;
Lloyd, AW;
... Lewis, AL; + view all
(2021)
Vandetanib-eluting radiopaque beads for chemoembolization: physicochemical evaluation and biological activity of vandetanib in hypoxia.
Anti-Cancer Drugs
10.1097/CAD.0000000000001082.
(In press).
|
|
Hall Hickman, Alexander;
Jenner, Richard G;
(2024)
Apparent RNA bridging between PRC2 and chromatin is an artifact of non-specific chromatin precipitation upon RNA degradation.
Cell Reports
, 43
(3)
, Article 113856. 10.1016/j.celrep.2024.113856.
|
|
Hartig, N;
(2013)
Role of VANGL1 as an effector of R-RAS.
Doctoral thesis (PhD), UCL (University College London).
|
|
Hartwig, T;
Montinaro, A;
von Karstedt, S;
Sevko, A;
Surinova, S;
Chakravarthy, A;
Taraborrelli, L;
... Walczak, H; + view all
(2017)
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.
Molecular Cell
, 65
(4)
pp. 730-742.
10.1016/j.molcel.2017.01.021.
|
|
Hasenoehrl, C;
Feuersinger, D;
Sturm, EM;
Bärnthaler, T;
Heitzer, E;
Graf, R;
Grill, M;
... Schicho, R; + view all
(2018)
G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.
International Journal of Cancer
, 142
(1)
pp. 121-132.
10.1002/ijc.31030.
|
|
Häsler, R;
Feng, Z;
Bäckdahl, L;
Spehlmann, ME;
Franke, A;
Teschendorff, A;
Rakyan, VK;
... Rosenstiel, P; + view all
(2012)
A functional methylome map of ulcerative colitis.
Genome Research
, 22
(11)
2130 -2137.
10.1101/gr.138347.112.
|
|
|
HAYNES, SR;
DOLLARD, C;
WINSTON, F;
BECK, S;
TROWSDALE, J;
DAWID, IB;
(1992)
The bromodomain - a conserved sequence found in human, drosophila and yeast proteins.
Nucleic Acids Research
, 20
(10)
2603 - 2603.
10.1093/nar/20.10.2603.
|
|
|
Henderson, S;
Pullabhatla, V;
Hertweck, A;
de Rinaldis, E;
Herrero, J;
Lord, GM;
Jenner, RG;
(2021)
The Th1 cell regulatory circuitry is largely conserved between human and mouse.
Life Science Alliance
, 4
(11)
, Article e202101075. 10.26508/lsa.202101075.
|
|
|
Henderson, S;
Chakravarthy, A;
Su, X;
Boshoff, C;
Fenton, TR;
(2014)
APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development.
Cell Rep
, 7
(6)
pp. 1833-1841.
10.1016/j.celrep.2014.05.012.
|
|
|
Henderson, S;
Fenton, T;
(2015)
APOBEC3 genes: retroviral restriction factors to cancer drivers.
Trends in Molecular Medicine
, 21
(5)
pp. 274-284.
10.1016/j.molmed.2015.02.007.
|
|
Henderson, SR;
Guiliano, D;
Presneau, N;
McLean, S;
Frow, R;
Vujovic, S;
Anderson, J;
... Boshoff, C; + view all
(2005)
A molecular map of mesenchymal tumors.
GENOME BIOL
, 6
(9)
, Article R76. 10.1186/gb-2005-6-9-r76.
|
|
|
Herrero, J;
Muffato, M;
Beal, K;
Fitzgerald, S;
Gordon, L;
Pignatelli, M;
Vilella, AJ;
... Flicek, P; + view all
(2016)
Database: The Journal of Biological Databases and Curation.
Database (Oxford)
, 2016
pp. 1-17.
10.1093/database/bav096.
|
|
|
Hertweck, A;
Jenner, RG;
(2021)
The Study of Protein–DNA Interactions in CD4+ T-Cells Using ChIPmentation.
Methods in Molecular Biology
, 2285
pp. 201-216.
10.1007/978-1-0716-1311-5_17.
|
|
Hertweck, Arnulf;
Vila de Mucha, Maria;
Barber, Paul R;
Dagil, Robert;
Porter, Hayley;
Ramos, Andres;
Lord, Graham M;
(2022)
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.
Nucleic Acids Research
, Article gkac258. 10.1093/nar/gkac258.
(In press).
|
|
Hertweck, A;
Evans, CM;
Eskandarpour, M;
Lau, JC;
Oleinika, K;
Jackson, I;
Kelly, A;
... Jenner, RG; + view all
(2016)
T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex.
Cell Reports
, 15
(12)
pp. 2756-2770.
10.1016/j.celrep.2016.05.054.
|
|
Hildebrandt, X;
Veli, Ö;
Hyoubi, A;
Zinngrebe, J;
Abdallah, AT;
Rodefeld, J;
Hoffmann, A;
... Peltzer, N; + view all
(2025)
Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome.
Science Advances
, 11
(38)
, Article eadw2539. 10.1126/sciadv.adw2539.
|
|
Hobor, S;
Al Bakir, M;
Hiley, CT;
Skrzypski, M;
Frankell, AM;
Bakker, B;
Watkins, TBK;
... Clipson, A; + view all
(2024)
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Nature Communications
, 15
, Article 4871. 10.1038/s41467-024-47606-9.
|
|
Huerne, Katherine;
Palmour, Nicole;
Wu, Angela Ruohao;
Beck, Stephan;
Berner, Alison;
Siebert, Reiner;
Joly, Yann;
(2022)
Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing.
The CRISPR Journal
10.1089/crispr.2021.0094.
|
|
Huettenhain, R;
Choi, M;
de la Fuente, LM;
Oehl, K;
Chang, C-YV;
Zimmermann, A-K;
Malander, S;
... Aebersold, R; + view all
(2019)
A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer.
Molecular & Cellular Proteomics
, 18
(9)
pp. 1836-1850.
10.1074/mcp.RA118.001221.
|
|
|
Hynds, Robert E;
Huebner, Ariana;
Pearce, David R;
Hil, Mark S;
Akarca, Ayse U;
Moore, David A;
Ward, Sophia;
... Swanton, Charles; + view all
(2024)
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nature Communications
, 15
, Article 4653. 10.1038/s41467-024-47547-3.
|
|
J
|
Jain, R;
Zhao, K;
Sheridan, JM;
Heinlein, M;
Kupresanin, F;
Abeysekera, W;
Hall, C;
... Gray, DHD; + view all
(2021)
Dual roles for LUBAC signaling in thymic epithelial cell development and survival.
Cell Death & Differentiation
, 28
(10)
pp. 2946-2956.
10.1038/s41418-021-00850-8.
|
|
Jamal-Hanjani, M;
Wilson, GA;
McGranahan, N;
Birkbak, NJ;
Watkins, TBK;
Veeriah, S;
Shafi, S;
... Swanton, C; + view all
(2017)
Tracking the Evolution of Non-Small-Cell Lung Cancer.
New England Journal of Medicine
, 376
(22)
pp. 2109-2121.
10.1056/NEJMoa1616288.
|
|
Johnston, IG;
Gaal, B;
Neves, RP;
Enver, T;
Iborra, FJ;
Jones, NS;
(2012)
Mitochondrial variability as a source of extrinsic cellular noise.
PLoS Comput Biol
, 8
(3)
, Article e1002416. 10.1371/journal.pcbi.1002416.
|
|
|
Jones, GG;
Del Río, IB;
Sari, S;
Sekerim, A;
Young, LC;
Hartig, N;
Areso Zubiaur, I;
... Rodriguez-Viciana, P; + view all
(2019)
SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.
Nature Communications
, 10
(1)
, Article 2532. 10.1038/s41467-019-10367-x.
|
|
|
Jones, Greg Gordon;
(2018)
The SHOC2 phosphatase complex as a therapeutic target for ERK pathway inhibition in RAS-driven tumors.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Jones, S;
King, PJ;
Antonescu, CN;
Sugiyama, MG;
Bhamra, A;
Surinova, S;
Angelopoulos, N;
... Hochhauser, D; + view all
(2020)
Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Scientific Reports
, 10
, Article 663. 10.1038/s41598-019-57153-9.
|
|
|
Joshi, K;
Robert de Massy, M;
Ismail, M;
Reading, JL;
Uddin, I;
Woolston, A;
Hatipoglu, E;
... Chain, B; + view all
(2019)
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Nature Medicine
, 25
pp. 1549-1559.
10.1038/s41591-019-0592-2.
|
|
Jovanovic, KK;
Tanic, M;
Ivanovic, I;
Gligorijevic, N;
Dojcinovic, BP;
Radulovic, S;
(2016)
Cell cycle, apoptosis, cellular uptake and whole-transcriptome microarray gene expression analysis of HeLa cells treated with a ruthenium(II)-arene complex with an isoquinoline-3-carboxylic acid ligand.
Journal of Inorganic Biochemistry
, 163
pp. 362-373.
10.1016/j.jinorgbio.2016.04.011.
|
|
|
Jozsa, F;
Gaier, C;
Ma, Y;
Kitchen, N;
McEvoy, A;
Miserocchi, A;
Samandouras, G;
... Darie, L; + view all
(2023)
Safety and efficacy of brain biopsy: Results from a single institution retrospective cohort study.
Brain and Spine
, 3
, Article 101763. 10.1016/j.bas.2023.101763.
|
|
Jørgensen, Andreas Christ Sølvsten;
Hill, Ciaran Scott;
Sturrock, Marc;
Tang, Wenhao;
Karamched, Saketh R;
Gorup, Dunja;
Lythgoe, Mark F;
... Shahrezaei, Vahid; + view all
(2023)
Data-driven spatio-temporal modelling of glioblastoma.
Royal Society Open Science
, 10
(3)
, Article 221444. 10.1098/rsos.221444.
|
K
|
Kanu, Nnennaya;
Lu, Wei-Ting;
Swanton, Charles;
Bartek, Jiri;
(2025)
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Nature Cell Biology
, 27
(1)
pp. 154-168.
10.1038/s41556-024-01558-w.
|
|
|
Kardooni, Hoda;
Gonzalez-Gualda, Estela;
Stylianakis, Emmanouil;
Saffaran, Sina;
Waxman, Jonathan;
Kypta, Robert M;
(2018)
CRISPR-Mediated Reactivation of DKK3 Expression Attenuates TGF-β Signaling in Prostate Cancer.
Cancers
, 10
(6)
p. 165.
10.3390/cancers10060165.
|
|
|
Karpathakis, A;
(2015)
Molecular profiling of gastrointestinal neuroendocrine tumours.
Doctoral thesis , UCL (University College London).
|
|
Karpathakis, A;
Dibra, H;
Pipinikas, C;
Feber, A;
Morris, T;
Francis, JM;
Oukrif, D;
... Thirlwell, C; + view all
(2017)
Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis.
Endocrine-Related Cancer
, 24
(2)
L21-L25.
10.1530/ERC-16-0419.
|
|
Kataria, M;
(2017)
How does Cdc14 order exit from mitosis?
Doctoral thesis , UCL (University College London).
|
|
Kataria, M;
Yamano, H;
(2019)
Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis.
MDPI — Cells
, 8
(8)
, Article 814. 10.3390/cells8080814.
|
|
|
Kato, I;
Nishinaka, Y;
Nakamura, M;
Akarca, AU;
Niwa, A;
Ozawa, H;
Yoshida, K;
... Enver, T; + view all
(2017)
Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.
Blood
, 129
(23)
pp. 3126-3129.
10.1182/blood-2016-06-721712.
|
|
Kelepouras, Konstantinos;
Saggau, Julia;
Bonasera, Debora;
Kiefer, Christine;
Locci, Federica;
Rakhsh-Khorshid, Hassan;
Grauvogel, Louisa;
... Liccardi, Gianmaria; + view all
(2025)
STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD.
Nature
10.1038/s41586-025-09536-4.
(In press).
|
|
Kenny, PA;
Enver, T;
Ashworth, A;
(2005)
Receptor and secreted targets of Wnt-I/beta-catenin signalling in mouse mammary epithelial cells.
BMC Cancer
, 5
, Article 3. 10.1186/1471-2407-5-3.
|
|
|
Kenny, PA;
Enver, T;
Ashworth, A;
(2002)
Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line.
BMC MOL BIOL
, 3
, Article 13. 10.1186/1471-2199-3-13.
|
|
|
Khan, A.;
(2008)
A screen for interactors of Lkb1 and a role for Lkb1 in the regulation of polarity in the Drosophila eye.
Doctoral thesis , University of London.
|
|
|
Khatun, Suniya;
(2024)
Computational Tool and Experimental Method Development for Unveiling Cell Competition with Mass Spectrometry.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Kleijn, Istvan T;
Martínez-Segura, Amalia;
Bertaux, François;
Saint, Malika;
Kramer, Holger;
Shahrezaei, Vahid;
Marguerat, Samuel;
(2022)
Growth-rate-dependent and nutrient-specific gene expression resource allocation in fission yeast.
Life Science Alliance
, 5
(5)
, Article e202101223. 10.26508/lsa.202101223.
|
|
Kling, T;
Wenger, A;
Beck, S;
Caren, H;
(2017)
Validation of the Methylation EPIC BeadChip for fresh-frozen and formalin-fixed paraffinembedded tumours.
Clinical Epigenetics
, 9
, Article 33. 10.1186/s13148-017-0333-7.
|
|
|
Koeferle, A;
Worf, K;
Breunig, C;
Baumann, V;
Herrero, J;
Wiesbeck, M;
Hutter, LH;
... Stricker, SH; + view all
(2016)
CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening.
BMC Genomics
, 17
, Article 917. 10.1186/s12864-016-3268-z.
|
|
|
Kolluri, KK;
Alifrangis, C;
Kumar, N;
Ishii, Y;
Price, S;
Michaut, M;
Williams, S;
... Janes, SM; + view all
(2018)
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.
eLIFE
, 7
, Article e30224. 10.7554/eLife.30224.
|
|
|
Koschny, R;
Brost, S;
Hinz, U;
Sykora, J;
Batke, EM;
Singer, S;
Breuhahn, K;
... Ganten, TM; + view all
(2013)
Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma.
BMC Cancer
, 13
, Article 532. 10.1186/1471-2407-13-532.
|
|
|
Krishna-Subramanian, S;
Singer, S;
Armaka, M;
Banales, JM;
Holzer, K;
Schirmacher, P;
Walczak, H;
... Kondylis, V; + view all
(2019)
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury.
Cell Death & Differentiation
10.1038/s41418-019-0330-9.
(In press).
|
|
Krusche, B;
Ottone, C;
clements, MP;
Johnstone, ER;
Goetsch, K;
Lieven, H;
Mota, SG;
... Parrinello, S; + view all
(2016)
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.
eLife
, 5
, Article e14845. 10.7554/eLife.14845.
|
|
|
Kuderna, LFK;
Tomlinson, C;
Hillier, LW;
Tran, A;
Fiddes, I;
Armstrong, J;
Laayouni, H;
... Marques-Bonet, T; + view all
(2017)
A 3-way hybrid approach to generate a new high quality chimpanzee reference genome (Pan_tro_3.0).
GigaScience
, 6
(11)
pp. 1-6.
10.1093/gigascience/gix098.
|
|
|
Kular, L;
Needhamsen, M;
Adzemovic, MZ;
Kramarova, T;
Gomez-Cabrero, D;
Ewing, E;
Piket, E;
... Jagodic, M; + view all
(2019)
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis.
Clinical Epigenetics
, 11
(1)
, Article 86. 10.1186/s13148-019-0678-1.
|
|
Kulis, M;
Merkel, A;
Heath, S;
Queirós, AC;
Schuyler, RP;
Castellano, G;
Beekman, R;
... Martín-Subero, JI; + view all
(2015)
Whole-genome fingerprint of the DNA methylome during human B cell differentiation.
Nature Genetics
, 47
(7)
pp. 746-756.
10.1038/ng.3291.
|
|
|
Kumari, R;
Hummerich, H;
Shen, X;
Fischer, M;
Litovchick, L;
Mittnacht, S;
DeCaprio, JA;
(2021)
Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence.
Scientific Reports
, 11
(1)
, Article 21506. 10.1038/s41598-021-01012-z.
|
|
|
Kupka, S;
(2017)
Regulation of theTNFR1-signalling complex by LUBAC and associated deubiquitinases.
Doctoral thesis , UCL (University College London).
|
|
|
Kupka, S;
De Miguel, D;
Draber, P;
Martino, L;
Surinova, S;
Rittinger, K;
Walczak, H;
(2016)
SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.
Cell Reports
, 16
(9)
pp. 2271-2280.
10.1016/j.celrep.2016.07.086.
|
L
|
La Paglia, L;
Listi, A;
Caruso, S;
Amodeo, V;
Passiglia, F;
Bazan, V;
Fanale, D;
(2017)
Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway.
PPAR Research
, 2017
, Article 8187235. 10.1155/2017/8187235.
|
|
|
Lafont, E;
Draber, P;
Rieser, E;
Reichert, M;
Kupka, S;
de Miguel, D;
Draberova, H;
... Walczak, H; + view all
(2018)
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.
Nature Cell Biology
, 20
(12)
pp. 1389-1399.
10.1038/s41556-018-0229-6.
|
|
Lafont, E;
Hartwig, T;
Walczak, H;
(2018)
Paving TRAIL's Path with Ubiquitin.
Trends in Biochemical Sciences
, 43
(1)
pp. 44-60.
10.1016/j.tibs.2017.11.002.
|
|
Lafont, E;
Kantari-Mimoun, C;
Draber, P;
De Miguel, D;
Hartwig, T;
Reichert, M;
Kupka, S;
... Walczak, H; + view all
(2017)
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.
EMBO Journal
, 36
(6)
, Article e201695699. 10.15252/embj.201695699.
|
|
|
Lagunas, Kristel Martinez;
Savcigil, Deniz Pinar;
Zrilic, Matea;
Fraile, Carlos Carvajal;
Craxton, Andrew;
Self, Emily;
Uranga-Murillo, Iratxe;
... Annibaldi, Alessandro; + view all
(2023)
Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair.
Science Advances
, 9
(30)
, Article eadg2829. 10.1126/sciadv.adg2829.
|
|
Lai, AG;
Pasea, L;
Banerjee, A;
Hall, G;
Denaxas, S;
Chang, WH;
Katsoulis, M;
... Hemingway, H; + view all
(2020)
Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.
BMJ Open
, 10
(11)
, Article e043828. 10.1136/bmjopen-2020-043828.
|
|
|
Lallo, A;
Frese, KK;
Morrow, CJ;
Sloane, R;
Gulati, S;
Schenk, MW;
Trapani, F;
... Dive, C; + view all
(2018)
The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer.
Clinical Cancer Research
, 24
(20)
pp. 5153-5164.
10.1158/1078-0432.CCR-17-2805.
|
|
Lamber, EP;
Beuron, F;
Morris, EP;
Svergun, DI;
Mittnacht, S;
(2013)
Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein.
PLoS One
, 8
(3)
, Article e58463. 10.1371/journal.pone.0058463.
|
|
|
Lämmle, Bernhard;
(2021)
Endothelial Dysfunction, Atherosclerosis, and Increase of Von Willebrand Factor and Factor VIII: A Randomized Controlled Trial in Swine.
Thrombosis and Haemostasis
, 121
(05)
p. 552.
10.1055/a-1347-8761.
|
|
Laun, K;
Coggill, P;
Palmer, S;
Sims, S;
Ning, ZM;
Ragoussis, J;
Volpi, E;
... Volz, A; + view all
(2006)
The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like loci.
PLoS Genetics
, 2
(5)
, Article e73. 10.1371/journal.pgen.0020073.
|
|
|
Law, PJ;
Berndt, SI;
Speedy, HE;
Camp, NJ;
Sava, GP;
Skibola, CF;
Holroyd, A;
... Slager, S; + view all
(2017)
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.
Nature Communications
, 8
, Article 14175. 10.1038/ncomms14175.
|
|
|
Lazebnik, Teddy;
Beck, Stephan;
Shami, Labib;
(2023)
Academic co-authorship is a risky game.
Scientometrics
, 128
, Article 12. 10.1007/s11192-023-04843-x.
|
|
Lechner, M;
Takahashi, Y;
Turri-Zanoni, M;
Liu, J;
Counsell, N;
Hermsen, M;
Kaur, RP;
... Hanna, EY; + view all
(2022)
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma.
European Journal of Cancer
, 162
pp. 221-236.
10.1016/j.ejca.2021.09.046.
|
|
Lechner, M;
Breeze, CE;
O'Mahony, JF;
Masterson, L;
(2019)
Early detection of HPV-associated oropharyngeal cancer.
[Letter].
Lancet
, 393
(10186)
p. 2123.
10.1016/S0140-6736(19)30227-2.
|
|
Lechner, M;
Fenton, T;
West, J;
Wilson, G;
Feber, A;
Henderson, S;
Thirlwell, C;
... Beck, S; + view all
(2013)
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Genome Medicine
, 5
(2)
p. 15.
10.1186/gm419.
|
|
|
Lechner, M;
Frampton, G;
Fenton, T;
Feber, A;
Palmer, G;
Jay, A;
Pillay, N;
... Boshoff, C; + view all
(2013)
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors.
Genome Medicine
, 5
, Article 49. 10.1186/gm453.
|
|
|
Lechner, M;
Jones, OS;
Breeze, CE;
Gilson, R;
(2019)
Gender-neutral HPV vaccination in the UK, rising male oropharyngeal cancer rates, and lack of HPV awareness.
[Letter].
Lancet Infectious Diseases
, 19
(2)
pp. 131-132.
10.1016/S1473-3099(18)30802-8.
|
|
Lee, L;
Alrasheed, N;
Khandelwal, G;
Fitzsimons, E;
Richards, H;
Wilson, W;
Chavda, SJ;
... Yong, K; + view all
(2021)
Increased Immune-Regulatory Receptor Expression on Effector T Cells as Early Indicators of Relapse Following Autologous Stem Cell Transplantation for Multiple Myeloma.
Frontiers Immunology
, 12
, Article 618610. 10.3389/fimmu.2021.618610.
|
|
|
Lee, RJ;
Khandelwal, G;
Baenke, F;
Cannistraci, A;
Macleod, K;
Mundra, P;
Ashton, G;
... Marais, R; + view all
(2020)
Brain microenvironment-driven resistance to immune and targeted therapies in acral melanoma.
ESMO Open
, 5
(4)
, Article e000707. 10.1136/esmoopen-2020-000707.
|
|
|
Lehmann, DJ;
Barnardo, MCNM;
Fuggle, S;
Quiroga, I;
Sutherland, A;
Warden, DR;
Barnetson, L;
... Smith, AD; + view all
(2006)
Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity?
J NEUROINFLAMM
, 3
, Article 33. 10.1186/1742-2094-3-33.
|
|
|
Lemay, J-F;
Marguerat, S;
Larochelle, M;
Liu, X;
Van Nues, R;
Hunyadkurti, J;
Hoque, M;
... Bachand, F; + view all
(2016)
The Nrd1-like protein Seb1 coordinates cotranscriptional 3′ end processing and polyadenylation site selection.
Genes and Development
, 30
(13)
pp. 1558-1572.
10.1101/gad.280222.116.
|
|
Lemke, J;
von Karstedt, S;
Abd El Hay, M;
Conti, A;
Arce, F;
Montinaro, A;
Papenfuss, K;
... Walczak, H; + view all
(2014)
Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1.
Cell Death Differ
, 21
(3)
pp. 491-502.
10.1038/cdd.2013.179.
|
|
|
Lemke, J;
von Karstedt, S;
Zinngrebe, J;
Walczak, H;
(2014)
Getting TRAIL back on track for cancer therapy.
Cell Death Differ
, 21
(9)
pp. 1350-1364.
10.1038/cdd.2014.81.
|
|
|
Leon, TE;
Rapoz-D'Silva, T;
Bertoli, C;
Rahman, S;
Magnussen, M;
Philip, B;
Farah, N;
... Mansour, MR; + view all
(2020)
EZH2 deficient T-cell acute lymphoblastic leukemia is sensitized to CHK1 inhibition through enhanced replication stress.
Cancer Discovery
, 10
(7)
10.1158/2159-8290.CD-19-0789.
|
|
Lewis, J;
Breeze, CE;
Charlesworth, J;
Maclaren, OJ;
Cooper, J;
(2016)
Where next for the reproducibility agenda in computational biology?
BMC Systems Biology
, 10
, Article 52. 10.1186/s12918-016-0288-x.
|
|
Li, Xiang;
Huang, Chun-Hao;
Sánchez-Rivera, Francisco J;
Kennedy, Margaret C;
Tschaharganeh, Darjus F;
Morris, John P;
Montinaro, Antonella;
... Lowe, Scott W; + view all
(2022)
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Proceedings of the National Academy of Sciences
, 119
(17)
, Article e2110557119. 10.1073/pnas.2110557119.
|
|
Li, Y;
Jiang, G;
Wu, W;
Yang, H;
Jin, Y;
Wu, M;
Liu, W;
... Chen, K; + view all
(2023)
Multi-omics integrated circulating cell-free DNA genomic signatures enhanced the diagnostic performance of early-stage lung cancer and postoperative minimal residual disease.
eBioMedicine
, 91
, Article 104553. 10.1016/j.ebiom.2023.104553.
|
|
Li, Y;
Wang, D;
Wang, L;
Yu, J;
Du, D;
Chen, Y;
Gao, P;
... Fu, S; + view all
(2013)
Distinct Genomic Aberrations between Low-Grade and High-Grade Gliomas of Chinese Patients.
PLoS ONE
, 8
(2)
, Article e57168. 10.1371/journal.pone.0057168.
|
|
|
Li, YR;
Zhu, JD;
Tian, G;
Li, N;
Li, QB;
Ye, MZ;
Zheng, HC;
... Zhang, XQ; + view all
(2010)
The DNA Methylome of Human Peripheral Blood Mononuclear Cells.
PLoS Biology
, 8
(11)
, Article e1000533. 10.1371/journal.pbio.1000533.
|
|
|
Libertini, E;
Heath, SC;
Hamoudi, RA;
Gut, M;
Ziller, MJ;
Czyz, A;
Ruotti, V;
... Beck, S; + view all
(2016)
Information recovery from low coverage whole-genome bisulfite sequencing.
Nature Communications
, 7
, Article 11306. 10.1038/ncomms11306.
|
|
|
Libertini, E;
Heath, SC;
Hamoudi, RA;
Gut, M;
Ziller, MJ;
Herrero, J;
Czyz, A;
... Beck, S; + view all
(2016)
Saturation analysis for whole-genome bisulfite sequencing data.
[Letter].
Nature Biotechnology
, 34
(7)
pp. 691-693.
10.1038/nbt.3524.
|
|
Lima, AF;
May, G;
Colunga, J;
Pedreiro, S;
Paiva, A;
Ferreira, L;
Enver, T;
... Pires das Neves, R; + view all
(2018)
Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation.
Scientific Reports
, 8
, Article 7210. 10.1038/s41598-018-25517-2.
|
|
|
Lima, AF;
May, G;
Díaz-Colunga, J;
Pedreiro, S;
Paiva, A;
Ferreira, L;
Enver, T;
... Pires das Neves, R; + view all
(2018)
Author Correction: Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation.
[Corrigendum].
Scientific Reportsvolume
, 8
, Article 11303. 10.1038/s41598-018-29328-3.
|
|
|
Linch, M;
Goh, G;
Hiley, C;
Shanmugabavan, Y;
McGranahan, N;
Rowan, A;
Wong, YNS;
... Swanton, C; + view all
(2017)
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of Oncology
, 28
(10)
pp. 2472-2480.
10.1093/annonc/mdx355.
|
|
Litchfield, K;
Reading, JL;
Lim, EL;
Xu, H;
Liu, P;
Al-Bakir, M;
Wong, YNS;
... Swanton, C; + view all
(2020)
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity.
Nature Communications
, 11
, Article 3800. 10.1038/s41467-020-17526-5.
|
|
|
Litchfield, K;
Reading, JL;
Puttick, C;
Thakkar, K;
Abbosh, C;
Bentham, R;
Watkins, TBK;
... Swanton, C; + view all
(2021)
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Cell
, 184
(3)
596-614.e14.
10.1016/j.cell.2021.01.002.
|
|
|
Litchfield, K;
Stanislaw, S;
Spain, L;
Gallegos, LL;
Rowan, A;
Schnidrig, D;
Rosenbaum, H;
... Turajlic, S; + view all
(2020)
Representative Sequencing: Unbiased Sampling of Solid Tumor Tissue.
Cell Reports
, 31
(5)
p. 107550.
10.1016/j.celrep.2020.107550.
|
|
Liu, TH;
Tang, YJ;
Huang, Y;
Wang, L;
Guo, XL;
Mi, JQ;
Liu, LG;
... Hong, DL; + view all
(2017)
Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin.
Leukemia
, 31
(5)
pp. 1079-1086.
10.1038/leu.2016.313.
|
|
Liu, Y;
Dodds, P;
Emilion, G;
Mungall, AJ;
Dunham, I;
Beck, S;
Wells, RS;
... Ganesan, TS; + view all
(2002)
The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.
BMC Genetics
, 3
, Article 20. 10.1186/1471-2156-3-20.
|
|
|
Lo, Jonathan W;
Schroeder, Jan-Hendrik;
Roberts, Luke B;
Mohamed, Rami;
Cozzetto, Domenico;
Beattie, Gordon;
Omer, Omer S;
... Lord, Graham M; + view all
(2024)
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner.
Nature Communications
, 15
(1)
, Article 9520. 10.1038/s41467-024-51719-6.
|
|
|
López, S;
Lim, EL;
Horswell, S;
Haase, K;
Huebner, A;
Dietzen, M;
Mourikis, TP;
... McGranahan, N; + view all
(2020)
Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution.
Nature Genetics
, 52
(3)
pp. 283-293.
10.1038/s41588-020-0584-7.
|
|
Lujan, Celia;
Tyler, Eleanor;
Ecker, Simone;
Webster, Amy;
Stead, Eleanor;
Martinez Miguel, Victoria;
Milligan, Deborah;
... Bjedov, Ivana; + view all
(2020)
A CellAgeClock for expedited discovery of anti-ageing compounds.
bioRxiv: Cold Spring Harbor, NY, USA.
|
|
|
Lyons Rimmer, J;
Ercolano, E;
Baiz, D;
Makhija, M;
Berger, A;
Sells, T;
Stroud, S;
... Hanemann, CO; + view all
(2020)
The Potential of MLN3651 in Combination with Selumetinib as a Treatment for Merlin-Deficient Meningioma.
Cancers
, 12
(7)
, Article 1744. 10.3390/cancers12071744.
|
|
|
Lyskjaer, I;
De Noon, S;
Tirabosco, R;
Rocha, AM;
Lindsay, D;
Amary, F;
Ye, H;
... Flanagan, AM; + view all
(2021)
DNA methylation-based profiling of bone and soft tissue tumours: a validation study of the 'DKFZ Sarcoma Classifier'.
The Journal of Pathology: Clinical Research
10.1002/cjp2.215.
(In press).
|
|
|
Lyskjær, Iben;
Kara, Neesha;
De Noon, Solange;
Davies, Christopher;
Rocha, Ana Maia;
Strobl, Anna-Christina;
Usher, Inga;
... Flanagan, Adrienne M; + view all
(2022)
Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.
European Journal of Cancer
, 168
pp. 1-11.
10.1016/j.ejca.2022.03.002.
|
|
M
|
MacGregor, TP;
Carter, R;
Gillies, RS;
Findlay, JM;
Kartsonaki, C;
Castro-Giner, F;
Sahgal, N;
... Sharma, RA; + view all
(2018)
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.
Scientific Reports
, 8
, Article 7265. 10.1038/s41598-018-24232-2.
|
|
Maher, GJ;
Ralph, HK;
Ding, Z;
Koelling, N;
Mlcochova, H;
Giannoulatou, E;
Dhami, P;
... Goriely, A; + view all
(2018)
Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.
Genome Research
, 28
(12)
pp. 1779-1790.
10.1101/gr.239186.118.
|
|
|
Maile, H;
Li, J-PO;
Gore, D;
Leucci, M;
Mulholland, P;
Hau, S;
Szabo, A;
... Pontikos, N; + view all
(2021)
Machine Learning Algorithms to Detect Subclinical Keratoconus: Systematic Review.
JMIR Medical Informatics
, 9
(12)
, Article e27363. 10.2196/27363.
|
|
Malyutina, S;
Chervova, O;
Tillmann, T;
Maximov, V;
Ryabikov, A;
Gafarov, V;
Hubacek, JA;
... Bobak, M; + view all
(2022)
The Relationship between Epigenetic Age and Myocardial Infarction/Acute Coronary Syndrome in a Population-Based Nested Case-Control Study.
Journal of Personalized Medicine
, 12
(1)
p. 110.
10.3390/jpm12010110.
|
|
|
Malyutina, Sofia;
Maximov, Vladimir;
Chervova, Olga;
Orlov, Pavel;
Ivanova, Anastasiya;
Mazdorova, Ekaterina;
Ryabikov, Andrew;
... Voevoda, Mikhail; + view all
(2023)
The Relationship between All-Cause Natural Mortality and Copy Number of Mitochondrial DNA in a 15-Year Follow-Up Study.
International Journal of Molecular Sciences
, 24
(13)
, Article 10469. 10.3390/ijms241310469.
|
|
Malyutina, Sofia;
Maximov, Vladimir;
Chervova, Olga;
Orlov, Pavel;
Voloshin, Vitaly;
Ryabikov, Andrew;
Voevoda, Mikhail;
(2023)
Leukocyte telomere length and mitochondrial DNA copy number association with colorectal cancer risk in an aging population.
Global Translational Medicine
, 2
(1)
, Article 184. 10.36922/gtm.v2i1.184.
|
|
Mansell, E;
Sigurdsson, V;
Deltcheva, E;
Brown, J;
James, C;
Miharada, K;
Soneji, S;
... Enver, T; + view all
(2020)
Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function.
Cell Stem Cell
10.1016/j.stem.2020.09.018.
(In press).
|
|
|
Marelli, S;
(2017)
Characterization of molecular pathways regulating the latent-to-lytic switch in γ-herpesviruses.
Doctoral thesis , UCL (University College London).
|
|
Marguerat, S;
Bähler, J;
(2012)
Coordinating genome expression with cell size.
Trends Genet
, 28
(11)
560 - 565.
10.1016/j.tig.2012.07.003.
|
|
|
Marguerat, S;
Lawler, K;
Brazma, A;
Bähler, J;
(2014)
Contributions of transcription and mRNA decay to gene expression dynamics of fission yeast in response to oxidative stress.
RNA Biol
, 11
(6)
702 - 714.
10.4161/rna.29196.
|
|
|
Marioni, RE;
Suderman, M;
Chen, BH;
Horvath, S;
Bandinelli, S;
Morris, T;
Beck, S;
... Hägg, S; + view all
(2019)
Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data.
The Journals of Gerontology: Series A
, 74
(1)
pp. 57-61.
10.1093/gerona/gly060.
|
|
|
Marqués-Torrejón, MÁ;
Williams, CAC;
Southgate, B;
Alfazema, N;
Clements, MP;
Garcia-Diaz, C;
Blin, C;
... Pollard, SM; + view all
(2021)
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Nature Communications
, 12
(1)
, Article 2594. 10.1038/s41467-021-22813-w.
|
|
|
Marshall, A;
Kasturiarachchi, J;
Datta, P;
Guo, Y;
Deltcheva, E;
James, C;
Brown, J;
... Nimmo, R; + view all
(2020)
Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes.
Scientific Reports
, 10
, Article 19390. 10.1038/s41598-020-76218-8.
|
|
Martinez-Miguel, VE;
Lujan, C;
Espie-Caullet, T;
Martinez-Martinez, D;
Moore, S;
Backes, C;
Gonzalez, S;
... Bjedov, I; + view all
(2021)
Increased fidelity of protein synthesis extends lifespan.
Cell Metabolism
10.1016/j.cmet.2021.08.017.
(In press).
|
|
|
Martynoga, B;
Mateo, JL;
Zhou, B;
Andersen, J;
Achimastou, A;
Urbán, N;
van den Berg, D;
... Guillemot, F; + view all
(2013)
Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence.
Genes Dev
, 27
(16)
1769 - 1786.
10.1101/gad.216804.113.
|
|
|
Marzi, SJ;
Leung, SK;
Ribarska, T;
Hannon, E;
Smith, AR;
Pishva, E;
Poschmann, J;
... Mill, J; + view all
(2018)
A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex.
Nature Neuroscience
, 21
pp. 1618-1627.
10.1038/s41593-018-0253-7.
|
|
Maselli, V;
Di Bernardo, D;
Banfi, S;
(2008)
CoGemiR: a comparative genomics microRNA database.
BMC Genomics
, 9
, Article 457. 10.1186/1471-2164-9-457.
|
|
|
Massoner, P;
Kugler, KG;
Unterberger, K;
Kuner, R;
Mueller, LAJ;
Fälth, M;
Schäfer, G;
... Klocker, H; + view all
(2013)
Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y.
PLOS One
, 8
(2)
, Article e55207. 10.1371/journal.pone.0055207.
|
|
|
May, G;
Soneji, S;
Tipping, AJ;
Teles, J;
McGowan, SJ;
Wu, M;
Guo, Y;
... Enver, T; + view all
(2013)
Dynamic Analysis of Gene Expression and Genome-wide Transcription Factor Binding during Lineage Specification of Multipotent Progenitors.
Cell Stem Cell
, 13
(6)
pp. 754-768.
10.1016/j.stem.2013.09.003.
|
|
|
McClellan, MJ;
Wood, CD;
Ojeniyi, O;
Cooper, TJ;
Kanhere, A;
Arvey, A;
Webb, HM;
... West, MJ; + view all
(2013)
Modulation of enhancer looping and differential gene targeting by epstein-barr virus transcription factors directs cellular reprogramming.
PLoS Pathogens
, 9
(9)
, Article e1003636. 10.1371/journal.ppat.1003636.
|
|
|
McErlean, P;
Bell, CG;
Hewitt, RJ;
Busharat, Z;
Ogger, PP;
Ghai, P;
Albers, GJ;
... Byrne, AJ; + view all
(2021)
DNA Methylome Alterations are Associated with Airway Macrophage Differentiation and Phenotype During Lung Fibrosis.
American Journal of Respiratory and Critical Care Medicine
, 204
(8)
pp. 954-966.
10.1164/rccm.202101-0004OC.
|
|
McGranahan, N;
Rosenthal, R;
Hiley, CT;
Rowan, AJ;
Watkins, TBK;
Wilson, GA;
Birkbak, NJ;
... Swanton, C; + view all
(2017)
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.
Cell
10.1016/j.cell.2017.10.001.
(In press).
|
|
|
McMaster, ML;
Berndt, S;
Zhang, J;
Slager, SL;
Li, SA;
Vajdic, CM;
Smedby, KE;
... Caporaso, NE; + view all
(2018)
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenstrom macroglobulinemia.
Nature Communications
, 9
, Article 4182. 10.1038/s41467-018-06541-2.
|
|
|
Meghini, Francesco;
Martins, Torcato;
Zhang, Qian;
Loyer, Nicolas;
Trickey, Michelle;
Abula, Yusanjiang;
Yamano, Hiroyuki;
... Kimata, Yuu; + view all
(2023)
APC/C-dependent degradation of Spd2 regulates centrosome asymmetry in Drosophila neural stem cells.
EMBO Reports
, Article e55607. 10.15252/embr.202255607.
|
|
Meghini, F;
Martins, T;
Tait, X;
Fujimitsu, K;
Yamano, H;
Glover, DM;
Kimata, Y;
(2016)
Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit.
Nature Communications
, 7
, Article 12607. 10.1038/ncomms12607.
|
|
|
Meijles, DN;
Zoumpoulidou, G;
Markou, T;
Rostron, KA;
Patel, R;
Lay, K;
Handa, BS;
... Clerk, A; + view all
(2019)
The cardiomyocyte “redox rheostat”: Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death.
Journal of Molecular and Cellular Cardiology
, 129
pp. 118-129.
10.1016/j.yjmcc.2019.02.006.
|
|
Mendoza-Naranjo, A;
El-Naggar, A;
Wai, DH;
Mistry, P;
Lazic, N;
Ayala, FR;
da Cunha, IW;
... Sorensen, PH; + view all
(2013)
ERBB4 confers metastatic capacity in Ewing sarcoma.
EMBO Mol Med
, 5
(7)
1019 - 1034.
10.1002/emmm.201202343.
|
|
|
Menger, L;
Sledzinska, A;
Bergerhoff, K;
Vargas, FA;
Smith, J;
Poirot, L;
Pule, M;
... Quezada, SA; + view all
(2016)
TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors.
Cancer Research
, 76
(8)
pp. 2087-2093.
10.1158/0008-5472.CAN-15-3352.
|
|
|
Migueles, RP;
Shaw, L;
Rodrigues, NP;
May, G;
Henseleit, K;
Anderson, KGV;
Goker, H;
... Enver, T; + view all
(2017)
Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny.
Developmental Biology
, 424
(2)
pp. 236-245.
10.1016/j.ydbio.2016.12.021.
|
|
Minoda, A.;
(2005)
The role of fission yeast nuclear actin-related protein in mitosis.
Doctoral thesis , University of London.
|
|
|
Mladenovic, J;
Susnjar, S;
Tanic, M;
Jankovic, R;
Karadzic, K;
Gavrilovic, D;
Stojanovic, S;
(2017)
Tumor response and patient outcome after preoperative radiotherapy in locally advanced non-inflammatory breast cancer patients.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology
, 22
(2)
pp. 325-333.
|
|
|
Moghul, Muhammad Ismail;
(2021)
Imputation Aided Methylation Analysis.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Moiseeva, V;
Amelina, H;
Collopy, LC;
Armstrong, CA;
Pearson, SR;
Tomita, K;
(2017)
The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast.
Cell Discovery
, 3
, Article 17041. 10.1038/celldisc.2017.41.
|
|
|
Moniz, LS;
Surinova, S;
Ghazaly, E;
Velasco, LG;
Haider, S;
Rodriguez-Prados, JC;
Berenjeno, IM;
... Vanhaesebroeck, B; + view all
(2017)
Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.
Scientific Reports
, 7
(39985)
10.1038/srep39985.
|
|
|
Montinaro, A;
Areso Zubiaur, I;
Saggau, J;
Kretz, A-L;
Ferreira, RMM;
Hassan, O;
Kitzig, E;
... Walczak, H; + view all
(2021)
Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers.
Cell Death & Differentiation
10.1038/s41418-021-00869-x.
(In press).
|
|
|
Montinaro, Antonella;
Walczak, Henning;
(2022)
Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries.
Cell Death & Differentiation
10.1038/s41418-022-01059-z.
(In press).
|
|
Montinaro, A;
Walczak, H;
(2018)
Sterile Inflammation Fuels Gastric Cancer.
Immunity
, 48
(3)
pp. 481-483.
10.1016/j.immuni.2018.03.011.
|
|
Moore, A;
Machiela, MJ;
Machado, M;
Wang, SS;
Kane, E;
Slager, SL;
Zhou, W;
... Berndt, SI; + view all
(2021)
Genome-wide homozygosity and risk of four non-Hodgkin lymphoma subtypes.
Journal of Translational Genetics and Genomics
, 5
pp. 200-217.
10.20517/jtgg.2021.08.
|
|
|
Moore, A;
Kane, E;
Wang, Z;
Panagiotou, OA;
Teras, LR;
Monnereau, A;
Wong Doo, N;
... Berndt, SI; + view all
(2019)
Genetically Determined Height and Risk of Non-hodgkin Lymphoma.
Frontiers in Oncology
, 9
, Article 1539. 10.3389/fonc.2019.01539.
|
|
|
Morris, TJ;
Beck, S;
(2015)
Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data.
Methods
, 72
3 - 8.
10.1016/j.ymeth.2014.08.011.
|
|
|
Mughal, S;
Moghul, I;
Yu, J;
Clark, T;
Gregory, DS;
Pontikos, N;
(2017)
Pheno4J: a gene to phenotype graph database.
Bioinformatics
, 33
(20)
pp. 3317-3319.
10.1093/bioinformatics/btx397.
|
|
|
Mutalima, N;
Molyneux, E;
Jaffe, H;
Kamiza, S;
Borgstein, E;
Mkandawire, N;
Liomba, G;
... Newton, R; + view all
(2008)
Associations between Burkitt Lymphoma among Children in Malawi and Infection with HIV, EBV and Malaria: Results from a Case-Control Study.
PLOS ONE
, 3
(6)
, Article e2505. 10.1371/journal.pone.0002505.
|
|
|
Myers, RM;
Stamatoyannopoulos, J;
Snyder, M;
Dunham, I;
Hardison, RC;
Bernstein, BE;
Gingeras, TR;
... Good, PJ; + view all
(2011)
A user's guide to the Encyclopedia of DNA elements (ENCODE).
PLoS Biology
, 9
(4)
, Article e1001046. 10.1371/journal.pbio.1001046.
|
|
N
|
Nguyen, HP;
Stewart, S;
Kukwikila, MN;
Jones, SF;
Offenbartl-Stiegert, D;
Mao, S;
Balasubramanian, S;
... Howorka, S; + view all
(2019)
A Photo‐responsive Small‐Molecule Approach for the Opto‐epigenetic Modulation of DNA Methylation.
Angewandte Chemie: International Edition
, 58
(20)
pp. 6620-6624.
10.1002/anie.201901139.
|
|
Nikitenko, LL;
Shimosawa, T;
Henderson, S;
Mäkinen, T;
Shimosawa, H;
Qureshi, U;
Pedley, RB;
... Boshoff, C; + view all
(2013)
Adrenomedullin haploinsufficiency predisposes to secondary lymphedema.
J Invest Dermatol
, 133
(7)
1768 - 1776.
10.1038/jid.2013.47.
|
|
|
Novakovic, B;
Sibson, M;
Ng, HK;
Manuelpillai, U;
Rakyan, V;
Down, T;
Beck, S;
... Saffery, R; + view all
(2009)
Placenta-specific methylation of the vitamin d 24-hydroxylase gene implications for feedback autoregulation of active vitamin d levels at the fetomaternal interface.
The journal of biological chemistry
, 284
(22)
14838 - 14848.
10.1074/jbc.M809542200.
|
|
|
Nowosad, A;
Besson, A;
(2020)
CDKN1B/p27 regulates autophagy via the control of Ragulator and MTOR activity in amino acid-deprived cells.
Autophagy
, 16
(12)
pp. 2297-2298.
10.1080/15548627.2020.1831217.
|
|
Nyoni, Lynet;
(2022)
Targeting the tumour microenvironment through death ligand inhibition.
Doctoral thesis (Ph.D), UCL (University College London).
|
O
|
O'Connor, David;
Demeulemeester, Jonas;
Conde, Lucia;
Kirkwood, Amy;
Fung, Kent;
Papaleonidopoulou, Foteini;
Bloye, Gianna;
... Mansour, Marc R; + view all
(2023)
The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia.
Journal of Clinical Oncology
10.1200/JCO.22.02734.
|
|
O'Connor, David;
Espejo Valle-Inclán, Jose;
Conde, Lucia;
Bloye, Gianna;
Rahman, Sunniyat;
Costa, Joana R;
Bartram, Jack;
... Mansour, Marc R; + view all
(2024)
Non-coding mutations drive persistence of a founder pre-leukemic clone which initiates late relapse in T-ALL.
Blood
, 143
(10)
pp. 933-937.
10.1182/blood.2023021906.
|
|
Oda, Hirotsugu;
Manthiram, Kalpana;
Chavan, Pallavi Pimpale;
Rieser, Eva;
Veli, Oenay;
Kaya, Oeykue;
Rauch, Charles;
... Kastner, Daniel L; + view all
(2024)
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Nature Immunology
, 25
(5)
pp. 764-777.
10.1038/s41590-024-01817-w.
|
|
|
Oka, A;
Asano, Y;
Hasegawa, M;
Fujimoto, M;
Ishikawa, O;
Kuwana, M;
Kawaguchi, Y;
... Ihn, H; + view all
(2017)
RXRB is a MHC-encoded susceptibility gene associated with anti-topoisomerase I antibody-positive systemic sclerosis.
Journal of Investigative Dermatology
, 137
(9)
pp. 1878-1886.
10.1016/j.jid.2017.04.028.
|
|
Oka, A;
Takagi, A;
Komiyama, E;
Yoshihara, N;
Mano, S;
Hosomichi, K;
Suzuki, S;
... Ikeda, S; + view all
(2020)
Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss.
EBioMedicine
, 57
, Article 102810. 10.1016/j.ebiom.2020.102810.
|
|
|
Olsson, M;
Beck, S;
Kogner, P;
Martinsson, T;
Carén, H;
(2016)
Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumors.
Epigenetics
pp. 1-11.
10.1080/15592294.2016.1138195.
|
|
Omer, Omer S;
Hertweck, Arnulf;
Roberts, Luke B;
Lo, Jonathan W;
Clough, Jennie N;
Jackson, Ian;
Pantazi, Eirini D;
... Lord, Graham M; + view all
(2022)
Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease.
Cellular and Molecular Gastroenterology and Hepatology
10.1016/j.jcmgh.2022.05.011.
(In press).
|
|
Ometto, G;
Moghul, I;
Montesano, G;
Hunter, A;
Pontikos, N;
Jones, P;
Keane, P;
... Crabb, D; + view all
(2019)
ReLayer: a free, online tool for extracting retinal thickness from cross-platform OCT images.
Translational Vision Science and Technology
, 8
(3)
, Article 25. 10.1167/tvst.8.3.25.
|
|
|
Ottone, Cristina;
Krusche, Benjamin;
Whitby, Ariadne;
Clements, Melanie;
Quadrato, Giorgia;
Pitulescu, Mara E;
Adams, Ralf H;
(2014)
Direct cell–cell contact with the vascular niche maintains quiescent neural stem cells.
Nature Cell Biology
, 16
(11)
pp. 1045-1056.
10.1038/ncb3045.
|
|
Owen, Nicholas;
Toms, Maria;
Tian, Yuan;
Toualbi, Lyes;
Richardson, Rose;
Young, Rodrigo;
Tracey-White, Dhani;
... Moosajee, Mariya; + view all
(2023)
Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina.
The Journal of Pathology
, 259
pp. 441-454.
10.1002/path.6056.
|
P
|
Pal, Debosree;
Neha, CV;
Bhaduri, Utsa;
Zenia, Zenia;
Dutta, Sangeeta;
Chidambaram, Subbulakshmi;
Rao, MRS;
(2021)
LncRNA Mrhl orchestrates differentiation programs in mouse embryonic stem cells through chromatin mediated regulation.
Stem Cell Research
, 53
, Article 102250. 10.1016/j.scr.2021.102250.
|
|
Pal, Debosree;
Patel, Manthan;
Boulet, Fanny;
Sundarraj, Jayakumar;
Grant, Olivia A;
Branco, Miguel R;
Basu, Srinjan;
... Pradeepa, Madapura M; + view all
(2023)
H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function.
Nature Structural & Molecular Biology
, 30
pp. 935-947.
10.1038/s41594-023-01016-5.
|
|
|
Pan, S;
Lai, H;
Shen, Y;
Breeze, C;
Beck, S;
Hong, T;
Wang, C;
(2017)
DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve.
Cardiovascular Research
, 113
(6)
pp. 692-704.
10.1093/cvr/cvx050.
|
|
Pataillot-Meakin, T;
Pillay, N;
Beck, S;
(2016)
3-methylcytosine in cancer: an underappreciated methyl lesion?
Epigenomics
, 8
(4)
pp. 451-454.
10.2217/epi.15.121.
|
|
Pathania, M;
De Jay, N;
Maestro, N;
Harutyunyan, AS;
Nitarska, J;
Pahlavan, P;
Henderson, S;
... Salomoni, P; + view all
(2017)
H3.3(K27M) Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Cancer Cell
, 32
(5)
, Article e9. 10.1016/j.ccell.2017.09.014.
|
|
Paul, DS;
Beck, S;
(2014)
Advances in epigenome-wide association studies for common diseases.
Trends in Molecular Medicine
, 20
(10)
pp. 541-543.
10.1016/j.molmed.2014.07.002.
|
|
|
Paul, DS;
Guilhamon, P;
Karpathakis, A;
Butcher, LM;
Thirlwell, C;
Feber, A;
Beck, S;
(2014)
Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.
Epigenetics
, 9
(5)
pp. 678-684.
10.4161/epi.28041.
|
|
|
Paul, DS;
Jones, A;
Sellar, RS;
Mayor, NP;
Feber, A;
Webster, AP;
Afonso, N;
... Beck, S; + view all
(2015)
A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation.
Genome Medicine
, 7
(1)
, Article 128. 10.1186/s13073-015-0246-z.
|
|
|
Paul, DS;
Soranzo, N;
Beck, S;
(2013)
Functional interpretation of non-coding sequence variation: Concepts and challenges.
Bioessays
, 36
(2)
pp. 191-199.
10.1002/bies.201300126.
|
|
|
Paul, DS;
Teschendorff, AE;
Dang, MA;
Lowe, R;
Hawa, MI;
Ecker, S;
Beyan, H;
... Leslie, RD; + view all
(2016)
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types.
Nature Communications
, 7
, Article 13555. 10.1038/ncomms13555.
|
|
Peltzer, N;
Darding, M;
Montinaro, A;
Draber, P;
Draberova, H;
Kupka, S;
Rieser, E;
... Walczak, H; + view all
(2018)
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Nature
, 557
(7703)
pp. 112-117.
10.1038/s41586-018-0064-8.
|
|
Peltzer, N;
Darding, M;
Walczak, H;
(2016)
Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling.
Trends in Cell Biology
, 26
(6)
pp. 445-461.
10.1016/j.tcb.2016.01.006.
|
|
|
Peltzer, N;
Rieser, E;
Taraborrelli, L;
Draber, P;
Darding, M;
Pemaute, B;
Shimizu, Y;
... Walczak, H; + view all
(2014)
HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death.
Cell Reports
, 9
(1)
pp. 153-165.
10.1016/j.celrep.2014.08.066.
|
|
|
Peltzer, N;
Walczak, H;
(2019)
Cell Death and Inflammation - A Vital but Dangerous Liaison.
Trends in Immunology
, 40
(5)
pp. 387-402.
10.1016/j.it.2019.03.006.
|
|
Peltzer, N;
Walczak, H;
(2019)
Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy.
Developmental Cell
, 48
(2)
pp. 127-128.
10.1016/j.devcel.2019.01.011.
|
|
Pescatore, A;
Esposito, E;
Draber, P;
Walczak, H;
Ursini, MV;
(2016)
NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II.
Cell Death and Disease
, 7
(ARTN e23)
10.1038/cddis.2016.245.
|
|
|
Petricevic, Branka;
Kabiljo, Julijan;
Zirnbauer, Rebecca;
Walczak, Henning;
Laengle, Johannes;
Bergmann, Michael;
(2022)
Neoadjuvant immunotherapy in gastrointestinal cancers - The new standard of care?
Seminars in Cancer Biology
, 86
(Pt 2)
pp. 834-850.
10.1016/j.semcancer.2022.05.015.
|
|
Pezic, Dubravka;
Weeks, Samuel;
Varsally, Wazeer;
Dewari, Pooran S;
Pollard, Steven;
Branco, Miguel R;
Hadjur, Suzana;
(2023)
The N-terminus of Stag1 is required to repress the 2C program by maintaining rRNA expression and nucleolar integrity.
Stem Cell Reports
10.1016/j.stemcr.2023.09.004.
|
|
|
Pezic, D;
Weeks, SL;
Hadjur, S;
(2017)
More to cohesin than meets the eye: complex diversity for fine-tuning of function.
Current Opinion in Genetics & Development
, 43
pp. 93-100.
10.1016/j.gde.2017.01.004.
|
|
|
Pignatelli, M;
Vilella, AJ;
Muffato, M;
Gordon, L;
White, S;
Flicek, P;
Herrero, J;
(2016)
ncRNA orthologies in the vertebrate lineage.
Database (Oxford)
, 2016
, Article bav127. 10.1093/database/bav127.
|
|
|
Pipinikas, C;
Dibra, H;
Karpathakis, A;
Feber, A;
Novelli, M;
Oukrif, D;
Fusai, G;
... Thirlwell, C; + view all
(2015)
Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours.
[Letter].
Endocrine-Related Cancer
, 22
(3)
L13-L18.
10.1530/ERC-15-0108.
|
|
Pollara, G;
Turner, CT;
Rosenheim, J;
Chandran, A;
Bell, LCK;
Khan, A;
Patel, A;
... Noursadeghi, M; + view all
(2021)
Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease.
Science Translational Medicine
, 13
(592)
, Article eabg7673. 10.1126/scitranslmed.abg7673.
|
|
|
Pontikos, N;
Murphy, C;
Moghul, I;
Arno, G;
Fujinami, K;
Fujinami, Y;
Sumodhee, D;
... UK Inherited Retinal Dystrophy Consortium, Phenopolis Consortium; + view all
(2020)
Phenogenon: Gene to phenotype associations for rare genetic diseases.
PLOS ONE
, 15
(4)
, Article e0230587. 10.1371/journal.pone.0230587.
|
|
|
Pontikos, N;
Yu, J;
Moghul, I;
Withington, L;
Blanco-Kelly, F;
Vulliamy, T;
Wong, TL;
... Plagnol, V; + view all
(2017)
Phenopolis: an open platform for harmonization and analysis of genetic and phenotypic data.
Bioinformatics
, 33
(15)
pp. 2421-2423.
10.1093/bioinformatics/btx147.
|
|
Popovic Krneta, Marina;
Sobic Saranovic, Dragana;
Mijatovic Teodorovic, Ljiljana;
Krajcinovic, Nemanja;
Avramovic, Natasa;
Bojovic, Zivko;
Bukumiric, Zoran;
... Tanic, Miljana; + view all
(2023)
Prediction of Cervical Lymph Node Metastasis in Clinically Node-Negative T1 and T2 Papillary Thyroid Carcinoma Using Supervised Machine Learning Approach.
Journal of Clinical Medicine
, 12
(11)
, Article 3641. 10.3390/jcm12113641.
|
|
Porter, Hayley;
Li, Yang;
Neguembor, Maria Victoria;
Beltran, Manuel;
Varsally, Wazeer;
Martin, Laura;
Cornejo, Manuel Tavares;
... Hadjur, Suzana; + view all
(2023)
Cohesin-independent STAG proteins interact with RNA and localise to R-loops to promote complex loading.
bioRxiv: Cold Spring Harbor, NY, USA.
|
|
|
Porter, Hayley;
Li, Yang;
Neguembor, Maria Victoria;
Beltran, Manuel;
Varsally, Wazeer;
Martin, Laura;
Cornejo, Manuel Tavares;
... Hadjur, Suzana; + view all
(2023)
Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading.
eLife
10.7554/eLife.79386.
(In press).
|
|
Pöysti, Anni;
(2023)
Understanding dormancy in Glioblastoma.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Priessner, M;
Gaboriau, DCA;
Sheridan, A;
Lenn, T;
Garzon-Coral, C;
Dunn, AR;
Chubb, JR;
... Laine, RF; + view all
(2024)
Content-aware frame interpolation (CAFI): deep learning-based temporal super-resolution for fast bioimaging.
Nature Methods
10.1038/s41592-023-02138-w.
(In press).
|
|
Priyann, A;
Woodcroft, BJ;
Rai, V;
Moghul, I;
Munagala, A;
Ter, F;
Chowdhary, H;
... Wurm, Y; + view all
(2019)
Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases.
Molecular Biology and Evolution
, 36
(12)
pp. 2922-2924.
10.1093/molbev/msz185.
|
|
|
Provenzano, L;
Ryan, Y;
Hilton, DA;
Lyons-Rimmer, J;
Dave, F;
Maze, EA;
Adams, CL;
... Hanemann, CO; + view all
(2017)
Cellular prion protein (PrPC) in the development of Merlin-deficient tumours.
Oncogene
, 36
pp. 6132-6142.
10.1038/onc.2017.200.
|
|
|
Puntervoll, P;
Linding, R;
Gemund, C;
Chabanis-Davidson, S;
Mattingsdal, M;
Cameron, S;
Martin, DM;
... Gibson, TJ; + view all
(2003)
ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.
Nucleic Acids Research
, 31
(13)
3625 - 3630.
10.1093/nar/gkg545.
|
|
|
Puttick, Clare;
Jones, Thomas P;
Leung, Michelle M;
Galvez-Cancino, Felipe;
Liu, Jiali;
Varas-Godoy, Manuel;
Rowan, Andrew;
... Mcgranahan, Nicholas; + view all
(2024)
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Nature Genetics
, 56
(10)
pp. 2121-2131.
10.1038/s41588-024-01883-8.
|
|
Q
|
Qing, Chen;
(2023)
Investigating secondary resistance to immunotherapy in a murine melanoma model: characterisation and potential therapeutic strategies.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Qureshi, Yasser M;
Voloshin, Vitaly;
Facchinelli, Luca;
McCall, Philip J;
Chervova, Olga;
Towers, Cathy E;
Covington, James A;
(2023)
Finding a Husband: Using Explainable AI to Define Male Mosquito Flight Differences.
Biology
, 12
(4)
, Article 496. 10.3390/biology12040496.
|
R
|
Rahman, Sunniyat;
Bloye, Gianna;
Farah, Nadine;
Demeulemeester, Jonas;
Costa, Joana R;
O'Connor, David;
Pocock, Rachael;
... Mansour, Marc R; + view all
(2024)
Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.
BLOOD
, 144
(22)
pp. 2319-2326.
10.1182/blood.2024024300.
|
|
|
Rakyan, VK;
Beyan, H;
Down, TA;
Hawa, MI;
Maslau, S;
Aden, D;
Daunay, A;
... Leslie, RD; + view all
(2011)
Identification of Type 1 Diabetes-Associated DNA Methylation Variable Positions That Precede Disease Diagnosis.
PLOS GENET
, 7
(9)
, Article e1002300. 10.1371/journal.pgen.1002300.
|
|
|
Rakyan, VK;
Hildmann, T;
Novik, KL;
Lewin, J;
Tost, J;
Cox, AV;
Andrews, TD;
... Beck, S; + view all
(2004)
DNA methylation profiling of the human major histocompatibility complex: A pilot study for the Human Epigenome Project.
PLOS BIOL
, 2
(12)
, Article e405. 10.1371/journal.pbio.0020405.
|
|
|
Ramos Zapatero, María;
(2023)
Single-cell screening of heterocellular patient-derived organoid drug responses.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
|
Reichert, M;
Bhamra, A;
Kupka, S;
Walczak, H;
(2018)
Characterization of the TNFR1-SC Using “Modified Tandem Affinity Purification” in Conjunction with Liquid Chromatography–Mass Spectrometry (LC-MS).
In: Ting, AT, (ed.)
Programmed Necrosis. Methods and Protocols.
(pp. 161-169).
Springer Nature: New York (NY), USA.
|
|
Reichert, Matthias;
(2017)
Regulation of TNFR1 signalling by LUBAC-dependent and -associated proteins.
Doctoral thesis , UCL (University College London).
|
|
Renfree, MB;
Papenfuss, AT;
Deakin, JE;
Lindsay, J;
Heider, T;
Belov, K;
Rens, W;
... Worley, KC; + view all
(2011)
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development.
GENOME BIOLOGY
, 12
(8)
10.1186/gb-2011-12-8-r81.
|
|
|
Ribeiro, S;
Napoli, I;
White, IJ;
Parrinello, S;
Flanagan, AM;
Suter, U;
Parada, LF;
(2013)
Injury Signals Cooperate with Nf1 Loss to Relieve the Tumor-Suppressive Environment of Adult Peripheral Nerve.
Cell Rep
, 5
(1)
pp. 126-136.
10.1016/j.celrep.2013.08.033.
|
|
|
Richardson, E;
Stockwell, SR;
Li, H;
Aherne, W;
Cuomo, ME;
Mittnacht, S;
(2012)
Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response.
PLOS ONE
, 7
(2)
, Article e31627. 10.1371/journal.pone.0031627.
|
|
|
Richardson, E;
Stockwell, SR;
Li, H;
Aherne, W;
Cuomo, ME;
Mittnacht, S;
(2012)
Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response.
PLoS One
, 7
(2)
, Article e31627. 10.1371/journal.pone.0031627.
|
|
|
Richardson, SE;
Ghazanfari, R;
Chhetri, J;
Enver, T;
Böiers, C;
(2021)
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture.
STAR Protocols
, 2
(2)
, Article 100420. 10.1016/j.xpro.2021.100420.
|
|
|
Ringham-Terry, Benjamin;
(2023)
The Role of SHOC2 in Skin Homeostasis and Inflammation.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Rizza, SA;
Challagundla, KB;
Natesampillai, S;
Bren, GD;
Sykora, J;
Walczak, H;
Badley, AD;
(2011)
TRAIL Dependent Fratricidal Killing of gp120 Primed Hepatocytes by HCV Core Expressing Hepatocytes.
PLoS ONE
, 6
(11)
, Article e27171. 10.1371/journal.pone.0027171.
|
|
|
Robbez-Masson, L;
Tie, CHC;
Conde, L;
Tunbak, H;
Husovsky, C;
Tchasovnikarova, IA;
Timms, RT;
... Rowe, HM; + view all
(2018)
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes.
Genome Research
, 28
(6)
pp. 836-845.
10.1101/gr.228171.117.
|
|
|
Roberts, Luke B;
Jowett, Geraldine M;
Read, Emily;
Zabinski, Tomas;
Berkachy, Rita;
Selkirk, Murray E;
Jackson, Ian;
... Lord, Graham M; + view all
(2021)
MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function.
The Journal of Immunology
, 206
(11)
pp. 2725-2739.
10.4049/jimmunol.2000647.
|
|
Robey, RC;
Lagos, D;
Gratrix, F;
Henderson, S;
Matthews, NC;
Vart, RJ;
Bower, M;
... Gotch, FM; + view all
(2009)
The CD8 and CD4 T-Cell Response against Kaposi's Sarcoma-Associated Herpesvirus Is Skewed Towards Early and Late Lytic Antigens.
PLOS ONE
, 4
(6)
, Article e5890. 10.1371/journal.pone.0005890.
|
|
|
Rodriguez, TA;
Srinivas, S;
Clements, MP;
Smith, JC;
Beddington, RSP;
(2005)
Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm.
Development
, 132
(11)
pp. 2513-2520.
10.1242/dev.01847.
|
|
Rodríguez-Hernández, Guillermo;
Casado-García, Ana;
Isidro-Hernández, Marta;
Picard, Daniel;
Raboso-Gallego, Javier;
Alemán-Arteaga, Silvia;
Orfao, Alberto;
... Vicente-Dueñas, Carolina; + view all
(2021)
The Second Oncogenic Hit Determines the Cell Fate of ETV6-RUNX1 Positive Leukemia.
Frontiers in Cell and Developmental Biology
, 9
, Article 704591. 10.3389/fcell.2021.704591.
|
|
Rodriguez-Lopez, Maria;
Anver, Shajahan;
Cotobal, Cristina;
Kamrad, Stephan;
Malecki, Michal;
Correia-Melo, Clara;
Hoti, Mimoza;
... Bähler, Jürg; + view all
(2022)
Correction: Functional profiling of long intergenic non-coding RNAs in fission yeast.
[Corrigendum].
eLife
, 11
, Article e77337. 10.7554/eLife.77337.
|
|
|
Roehrig, AE;
Klupsch, K;
Oses-Prieto, JA;
Chaib, S;
Henderson, S;
Emmett, W;
Young, LC;
... Rodriguez-Viciana, P; + view all
(2021)
Cell-cell adhesion regulates Merlin/NF2 interaction with the PAF complex.
PLoS One
, 16
(8)
, Article e0254697. 10.1371/journal.pone.0254697.
|
|
|
Roques, M;
Wall, RJ;
Douglass, AP;
Ramaprasad, A;
Ferguson, DJ;
Kaindama, ML;
Brusini, L;
... Tewari, R; + view all
(2015)
Plasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in Mosquitoes.
PLOS Pathogens
, 11
(11)
, Article e1005273. 10.1371/journal.ppat.1005273.
|
|
|
Ros, Uris;
Martinez-Osorio, Veronica;
Valiente, Pedro A;
Abdelwahab, Yasmin;
Gojkovic, Milos;
Shalaby, Raed;
Zanna, Silvia;
... Garcia-Saez, Ana J; + view all
(2025)
MLKL activity requires a splicing-regulated, druggable intramolecular interaction.
Molecular Cell
, 85
(8)
pp. 1589-1605.
10.1016/j.molcel.2025.03.015.
|
|
Rosenthal, R;
Cadieux, EL;
Salgado, R;
Bakir, MA;
Moore, DA;
Hiley, CT;
Lund, T;
... TRACERx consortium; + view all
(2019)
Neoantigen-directed immune escape in lung cancer evolution.
Nature
10.1038/s41586-019-1032-7.
(In press).
|
|
Rosenthal, R;
McGranahan, N;
Herrero, J;
Swanton, C;
(2017)
Deciphering Genetic Intratumor Heterogeneity and Its Impact on Cancer Evolution.
Annual Review of Cancer Biology
, 1
pp. 223-240.
10.1146/annurev-cancerbio-042516-011348.
|
|
Rosenthal, R;
McGranahan, N;
Herrero, J;
Taylor, BS;
Swanton, C;
(2016)
deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution.
Genome Biol
, 17
(1)
p. 31.
10.1186/s13059-016-0893-4.
|
|
Rudan, MV;
Barrington, C;
Henderson, S;
Ernst, C;
Odom, DT;
Tanay, A;
Hadjur, S;
(2015)
Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture.
Cell Reports
, 10
(8)
pp. 1297-1309.
10.1016/j.celrep.2015.02.004.
|
|
|
Rydström, A;
Grahn, THM;
Niroula, A;
Mansell, E;
van der Garde, M;
Pertesi, M;
Subramaniam, A;
... Karlsson, S; + view all
(2023)
Functional and molecular profiling of hematopoietic stem cells during regeneration.
Experimental Hematology
10.1016/j.exphem.2023.08.010.
|
|
S
|
Saint, M;
Bertaux, F;
Tang, W;
Sun, X-M;
Game, L;
Köferle, A;
Bähler, J;
... Marguerat, S; + view all
(2019)
Single-cell imaging and RNA sequencing reveal patterns of gene expression heterogeneity during fission yeast growth and adaptation.
Nature Microbiology
, 4
(3)
pp. 480-491.
10.1038/s41564-018-0330-4.
|
|
Sajic, T;
Liu, Y;
Arvaniti, E;
Surinova, S;
Williams, EG;
Schiess, R;
Hüttenhain, R;
... Aebersold, R; + view all
(2018)
Similarities and Differences of Blood N-Glycoproteins in Five Solid Carcinomas at Localized Clinical Stage Analyzed by SWATH-MS.
Cell Reports
, 23
(9)
2819-2831.e5.
10.1016/j.celrep.2018.04.114.
|
|
|
Sakthivelu, Vignesh;
Schmitt, Anna;
Odenthal, Franka;
Ndoci, Kristiano;
Touet, Marian;
Shaib, Ali H;
Chihab, Abdulla;
... Beleggia, Filippo; + view all
(2025)
Functional synapses between neurons and small cell lung cancer.
Nature
10.1038/s41586-025-09434-9.
(In press).
|
|
Salomonsen, J;
Chattaway, JA;
Chan, AC;
Parker, A;
Huguet, S;
Marston, DA;
Rogers, SL;
... Kaufman, J; + view all
(2014)
Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns.
PLoS Genetics
, 10
(6)
, Article e1004417. 10.1371/journal.pgen.1004417.
|
|
|
Sambrook, JG;
Bashirova, A;
Andersen, H;
Piatak, M;
Vernikos, GS;
Coggill, P;
Lifson, JD;
... Beck, S; + view all
(2006)
Identification of the ancestral killer immunoglobulin-like receptor gene in primates.
BMC GENOMICS
, 7
, Article 209. 10.1186/1471-2164-7-209.
|
|
|
Sambrook, JG;
Figueroa, F;
Beck, S;
(2005)
A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish.
BMC GENOMICS
, 6
, Article 152. 10.1186/1471-2164-6-152.
|
|
|
Santos e Sousa, P;
Ciré, S;
Conlan, T;
Jardine, L;
Tkacz, C;
Ferrer, IR;
Lomas, C;
... Chakraverty, R; + view all
(2018)
Peripheral tissues re-program CD8+ T cells for pathogenicity during graftversus- host disease.
JCI Insight
, 3
(5)
, Article e97011. 10.1172/jci.insight.97011.
|
|
|
Saulnier, KM;
Bujold, D;
Dyke, SOM;
Dupras, C;
Beck, S;
Bourque, G;
Joly, Y;
(2019)
Benefits and barriers in the design of harmonized access agreements for international data sharing.
Scientific Data
, 6
, Article 297. 10.1038/s41597-019-0310-4.
|
|
|
Schaller, T;
Ocwieja, KE;
Rasaiyaah, J;
Price, AJ;
Brady, TL;
Roth, SL;
Hué, S;
... Towers, GJ; + view all
(2011)
HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.
PLoS Pathog
, 7
(12)
, Article e1002439. 10.1371/journal.ppat.1002439.
|
|
|
Schiffmann, LM;
de Groot, E;
Albert, MC;
Quaas, A;
dos Santos, D Pinto;
Babic, B;
Fuchs, HF;
... van Hillegersberg, R; + view all
(2023)
Laparoscopic ischemic conditioning of the stomach prior to esophagectomy induces gastric neo-angiogenesis.
European Journal of Surgical Oncology
, 49
(11)
, Article 107096. 10.1016/j.ejso.2023.107096.
|
|
|
Schütte, M;
Risch, T;
Abdavi-Azar, N;
Boehnke, K;
Schumacher, D;
Keil, M;
Yildiriman, R;
... Yaspo, ML; + view all
(2017)
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.
Nature Communications
, 8
, Article 14262. 10.1038/ncomms14262.
|
|
Serbanovic-Canic, J;
de Luca, A;
Warboys, C;
Ferreira, PF;
Luong, LA;
Hsiao, S;
Gauci, I;
... Evans, PC; + view all
(2017)
Zebrafish Model for Functional Screening of Flow-Responsive Genes.
Arteriosclerosis, Thrombosis and Vascular Biology
, 37
(1)
pp. 130-143.
10.1161/ATVBAHA.116.308502.
|
|
|
Shimizu, Y;
(2017)
Molecular and functional characterisation of linear ubiquitination in the liver.
Doctoral thesis , UCL (University College London).
|
|
Shimizu, Y;
Peltzer, N;
Sevko, A;
Lafont, E;
Sarr, A;
Draberova, H;
Walczak, H;
(2017)
The linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis.
Hepatology
, 65
(6)
pp. 1963-1978.
10.1002/hep.29074.
|
|
|
Shimizu, Y;
Taraborrelli, L;
Walczak, H;
(2015)
Linear ubiquitination in immunity.
Immunol Rev
, 266
(1)
pp. 190-207.
10.1111/imr.12309.
|
|
Shroff, Aditya Shishir;
(2023)
Deciphering the role of mutant IDH in gliomas via development of novel in vivo models.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Siddle, HV;
Deakin, JE;
Coggill, P;
Whilming, L;
Harrow, J;
Kaufman, J;
Beck, S;
(2011)
The tammar wallaby major histocompatibility complex shows evidence of past genomic instability.
BMC GENOMICS
, 12
, Article 421. 10.1186/1471-2164-12-421.
|
|
|
Silvestre Patallo, I;
Carter, R;
Maughan, D;
Nisbet, A;
Schettino, G;
Subiel, A;
(2021)
Evaluation of a micro ionization chamber for dosimetric measurements in image-guided preclinical irradiation platforms.
Physics in Medicine and Biology
10.1088/1361-6560/ac3b35.
(In press).
|
|
Simpson Ragdale, Holly;
Clements, Melanie;
Tang, Wenhao;
Deltcheva, Elitza;
Andreassi, Catia;
Lai, Alvina G;
Chang, Wai Hoong;
... Parrinello, Simona; + view all
(2023)
Injury primes mutation-bearing astrocytes for dedifferentiation in later life.
Current Biology
10.1016/j.cub.2023.02.013.
(In press).
|
|
Simpson Ragdale, Holly;
(2020)
p53 restricts injury-induced plasticity in cortical astrocytes.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Singh, A;
Mishra, A;
Khosravi, A;
Khandelwal, G;
Jayaram, B;
(2017)
Physico-chemical fingerprinting of RNA genes.
Nucleic Acids Research
, 45
(7)
, Article e47. 10.1093/nar/gkw1236.
|
|
|
Singh, HD;
Otano, I;
Rombouts, K;
Singh, KP;
Peppa, D;
Gill, US;
Bottcher, K;
... Maini, MK; + view all
(2017)
TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis.
Scientific Reports
, 7
, Article 5514. 10.1038/s41598-017-05845-5.
|
|
|
Sivakumaran, S;
Henderson, S;
De Ascensao Santos E Sousa, P;
Ward, S;
Chakraverty, R;
Bennett, CL;
(2014)
Depletion of DC drives expansion of a unique population of monocytes poised for innate immune activation.
Presented at: 13th International Symposium on Dendritic Cells (DC 2014), Tours, France.
|
|
Sivakumaran, S;
Henderson, S;
Ward, S;
Santos E Sousa, P;
Manzo, T;
Zhang, L;
Conlan, T;
... Bennett, CL; + view all
(2016)
Depletion of CD11c(+) cells in the CD11c.DTR model drives expansion of unique CD64(+) Ly6C(+) monocytes that are poised to release TNF-α.
European Journal of Immunology
, 46
(1)
pp. 192-203.
10.1002/eji.201545789.
|
|
|
Skalska, L;
Begley, V;
Beltran, M;
Lukauskas, S;
Khandelwal, G;
Faull, P;
Bhamra, A;
... Jenner, RG; + view all
(2021)
Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin.
Molecular Cell
, 81
(14)
2944-2959.e10.
10.1016/j.molcel.2021.05.026.
|
|
Skalska, L;
Beltran-Nebot, M;
Ule, J;
Jenner, RG;
(2017)
Regulatory feedback from nascent RNA to chromatin and transcription.
Nature Reviews Molecular Cell Biology
, 18
(5)
pp. 331-337.
10.1038/nrm.2017.12.
|
|
Skinner, BM;
Sargent, CA;
Churcher, C;
Hunt, T;
Herrero, J;
Loveland, JE;
Dunn, M;
... Tyler-Smith, C; + view all
(2016)
The pig X and Y Chromosomes: structure, sequence, and evolution.
Genome Research
, 26
(1)
pp. 130-139.
10.1101/gr.188839.114.
|
|
|
Smeeth, Demelza;
Beck, Stephan;
Karam, Elie G;
Pluess, Michael;
(2021)
The role of epigenetics in psychological resilience.
The Lancet Psychiatry
, 8
(7)
pp. 620-629.
10.1016/S2215-0366(20)30515-0.
|
|
Smeeth, Demelza;
Ecker, Simone;
Chervova, Olga;
McEwen, Fiona;
Karam, Elie;
Beck, Stephan;
Pluess, Michael;
(2024)
War Exposure and DNA Methylation in Syrian Refugee Children and Adolescents.
JAMA Psychiatry
10.1001/jamapsychiatry.2024.3714.
(In press).
|
|
Soderquest, K;
Hertweck, A;
Giambartolomei, C;
Henderson, S;
Mohamed, R;
Goldberg, R;
Perucha, E;
... Lord, GM; + view all
(2017)
Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease.
PLOS GENETICS
, 13
(2)
10.1371/journal.pgen.1006587.
|
|
|
Sousa-Nunes, R;
Rana, AA;
Kettleborough, R;
Brickman, JM;
Clements, M;
Forrest, A;
Grimmond, S;
... Beddington, RS; + view all
(2003)
Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.
Genome Research
, 13
(12)
pp. 2609-2620.
10.1101/gr.1362303.
|
|
|
Spit, M;
Rieser, E;
Walczak, H;
(2019)
Linear ubiquitination at a glance.
Journal of Cell Science
, 132
(2)
, Article jcs208512. 10.1242/jcs.208512.
|
|
Srinivas, S;
Rodriguez, T;
Clements, M;
Smith, JC;
Beddington, RSP;
(2004)
Active cell migration drives the unilateral movements of the anterior visceral endoderm.
Development
, 131
(5)
pp. 1157-1164.
10.1242/dev.01005.
|
|
Stathopoulou, A;
Chhetri, JB;
Ambrose, JC;
Estève, P-O;
Ji, L;
Erdjument-Bromage, H;
Zhang, G;
... Ooi, SKT; + view all
(2017)
A novel requirement for DROSHA in maintenance of mammalian CG methylation.
Nucleic Acids Research
, 45
(16)
pp. 9398-9412.
10.1093/nar/gkx695.
|
|
Stathopoulou, A;
Chhetri, JB;
Ambrose, JC;
Estève, P-O;
Ji, L;
Erdjument-Bromage, H;
Zhang, G;
... Ooi, SKT; + view all
(2017)
A novel requirement for DROSHA in maintenance of mammalian CG methylation.
[Corrigendum].
Nucleic Acids Research
, 45
(16)
p. 9810.
10.1093/nar/gkx736.
|
|
|
Stavish, D;
Böiers, C;
Price, C;
Frith, TJR;
Halliwell, J;
Saldaña-Guerrero, I;
Wray, J;
... Enver, T; + view all
(2020)
Generation and trapping of a mesoderm biased state of human pluripotency.
Nature Communications
, 11
, Article 4989. 10.1038/s41467-020-18727-8.
|
|
|
Steele, CD;
Tarabichi, M;
Oukrif, D;
Webster, AP;
Ye, H;
Fittall, M;
Lombard, P;
... Pillay, N; + view all
(2019)
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways.
Cancer Cell
, 35
(3)
441-456.e8.
10.1016/j.ccell.2019.02.002.
|
|
|
Stewart, SK;
Morris, TJ;
Guilhamon, P;
Bulstrode, H;
Bachman, M;
Balasubramanian, S;
Beck, S;
(2014)
oxBS-450K: A method for analysing hydroxymethylation using 450K BeadChips.
Methods
, 72
pp. 9-15.
10.1016/j.ymeth.2014.08.009.
|
|
|
Stockwell, SR;
Mittnacht, S;
(2017)
High-Content Imaging and RNAi Screens for Investigating Kinase Network Plasticity.
Kinase Signaling Networks
, 1636
pp. 133-161.
10.1007/978-1-4939-7154-1_10.
|
|
|
Stockwell, SR;
Mittnacht, S;
(2014)
Workflow for high-content, individual cell quantification of fluorescent markers from universal microscope data, supported by open source software.
Journal of Visualized Experiments
(94)
, Article e51882. 10.3791/51882.
|
|
Stockwell, SR;
Platt, G;
Barrie, SE;
Zoumpoulidou, G;
Te Poele, RH;
Aherne, GW;
Wilson, SC;
... Mittnacht, S; + view all
(2012)
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
PLOS One
, 7
(1)
, Article e28568. 10.1371/journal.pone.0028568.
|
|
|
Stricker, SH;
Koferle, A;
Beck, S;
(2017)
From profiles to function in epigenomics.
[Review].
Nature Reviews Genetics
, 18
(1)
pp. 51-66.
10.1038/nrg.2016.138.
|
|
Stuckey, Daniel W;
Clements, Melanie;
Di-Gregorio, Aida;
Senner, Claire E;
Le Tissier, Paul;
Srinivas, Shankar;
Rodriguez, Tristan A;
(2011)
Coordination of cell proliferation and anterior-posterior axis establishment in the mouse embryo.
Development
, 138
(8)
pp. 1521-1530.
10.1242/dev.063537.
|
|
Stuckey, DW;
Di Gregorio, A;
Clements, M;
Rodriguez, TA;
(2011)
Correct Patterning of the Primitive Streak Requires the Anterior Visceral Endoderm.
PLoS ONE
, 6
(3)
, Article e17620. 10.1371/journal.pone.0017620.
|
|
Stunnenberg, HG;
Abrignani, S;
Adams, D;
de Almeida, M;
Altucci, L;
Amin, V;
Amit, I;
... Kim, SC; + view all
(2016)
The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery.
Cell
, 167
(5)
pp. 1145-1149.
10.1016/j.cell.2016.11.007.
|
|
Sun, Xi-Ming;
Bowman, Anthony;
Priestman, Miles;
Bertaux, Francois;
Martinez-Segura, Amalia;
Tang, Wenhao;
Whilding, Chad;
... Marguerat, Samuel; + view all
(2020)
Size-Dependent Increase in RNA Polymerase II Initiation Rates Mediates Gene Expression Scaling with Cell Size.
Current Biology
, 30
(7)
1217-1230.e7.
10.1016/j.cub.2020.01.053.
|
|
Swanton, C;
Beck, SA;
(2014)
Epigenetic noise fuels cancer evolution.
Cancer Cell
, 26
(6)
pp. 775-776.
10.1016/j.ccell.2014.11.003.
|
|
|
Szlosarek, PW;
Steele, JP;
Nolan, L;
Gilligan, D;
Taylor, P;
Spicer, J;
Lind, M;
... Hackshaw, A; + view all
(2017)
Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma A Randomized Clinical Trial.
JAMA Oncology
, 3
(1)
pp. 58-66.
10.1001/jamaoncol.2016.3049.
|
T
|
Taiwo, O;
Wilson, GA;
Emmett, W;
Morris, T;
Bonnet, D;
Schuster, E;
Adejumo, T;
... Pearce, DJ; + view all
(2013)
DNA methylation analysis of murine hematohematopoietic side population cells during aging.
Epigenetics
, 8
(10)
pp. 1114-1122.
10.4161/epi.26017.
|
|
|
Tan, G;
Muffato, M;
Ledergerber, C;
Herrero, J;
Goldman, N;
Gil, M;
Dessimoz, C;
(2015)
Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference.
Systematic Biology
, 64
(5)
pp. 778-791.
10.1093/sysbio/syv033.
|
|
|
Tanic, Miljana;
Ecker, Simone;
Lyskjaer, Iben;
(2024)
Editorial: Epigenetic biomarkers for cancer risk stratification and patient management.
Frontiers in Genetics
, 15
, Article 1421500. 10.3389/fgene.2024.1421500.
|
|
|
Tanić, Miljana;
Moghul, Ismail;
Rodney, Simon;
Dhami, Pawan;
Vaikkinen, Heli;
Ambrose, John;
Barrett, James;
... Beck, Stephan; + view all
(2022)
Comparison and imputation-aided integration of five commercial platforms for targeted DNA methylome analysis.
Nature Biotechnology
, 40
pp. 1478-1487.
10.1038/s41587-022-01336-9.
|
|
Tanic, M;
Beck, S;
(2017)
Cell-free DNA: Treasure trove for cancer medicine.
Nature Materials
, 16
(11)
pp. 1056-1057.
10.1038/nmat5019.
|
|
Tanic, M;
Beck, S;
(2017)
Epigenome-wide association studies for cancer biomarker discovery in circulating cell-free DNA: technical advances and challenges.
Current Opinion in Genetics and Development
, 42
pp. 48-55.
10.1016/j.gde.2017.01.017.
|
|
|
Tanić, M;
Krivokuća, A;
Čavić, M;
Mladenović, J;
Plesinac Karapandžić, V;
Beck, S;
Radulović, S;
... Janković, R; + view all
(2018)
Molecular signature of response to preoperative radiotherapy in locally advanced breast cancer.
Radiation Oncology
, 13
(1)
, Article 193. 10.1186/s13014-018-1129-4.
|
|
|
Taraborrelli, L;
(2017)
The Role Of Lubac In Tissue Homeostasis And Cancer.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Taraborrelli, L;
Peltzer, N;
Montinaro, A;
Kupka, S;
Rieser, E;
Hartwig, T;
Sarr, A;
... Walczak, H; + view all
(2018)
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.
Nature Communications
, 9
(1)
, Article 3910. 10.1038/s41467-018-06155-8.
|
|
|
Tavares, Manuel;
Khandelwal, Garima;
Muter, Joanne;
Viiri, Keijo;
Beltran, Manuel;
Brosens, Jan J;
Jenner, Richard G;
(2022)
JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation.
Cell Reports
, 39
(9)
, Article 110889. 10.1016/j.celrep.2022.110889.
|
|
Tavares Cornejo, Manuel de Jesus;
(2020)
Disregulation of PRC2 function caused by the JAZF1-SUZ12 fusion protein.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Teh, CE;
Lalaoui, N;
Jain, R;
Policheni, AN;
Heinlein, M;
Alvarez-Diaz, S;
Sheridan, JM;
... Gray, DH; + view all
(2016)
Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis.
Nat Commun
, 7
, Article 13353. 10.1038/ncomms13353.
|
|
|
Teixeira, VH;
Pipinikas, CP;
Pennycuick, A;
Lee-Six, H;
Chandrasekharan, D;
Beane, J;
Morris, TJ;
... Janes, SM; + view all
(2019)
Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.
Nature Medicine
, 25
pp. 517-525.
10.1038/s41591-018-0323-0.
|
|
Teles, J;
Pina, C;
Edén, P;
Ohlsson, M;
Enver, T;
Peterson, C;
(2013)
Transcriptional regulation of lineage commitment - a stochastic model of cell fate decisions.
PLoS Computational Biology
, 9
(8)
, Article e1003197. 10.1371/journal.pcbi.1003197.
|
|
|
Teschendorff, AE;
Breeze, CE;
Zheng, SC;
Beck, S;
(2017)
A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies.
BMC Bioinformatics
, 18
(1)
, Article 105. 10.1186/s12859-017-1511-5.
|
|
Teschendorff, AE;
Enver, T;
(2017)
Single-cell entropy for accurate estimation of differentiation potency from a cell's transcriptome.
Nature Communications
, 8
, Article 15599. 10.1038/ncomms15599.
|
|
Teschendorff, AE;
Lee, SH;
Jones, A;
Fiegl, H;
Kalwa, M;
Wagner, W;
Chindera, K;
... Widschwendter, M; + view all
(2015)
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer.
Genome Medicine
, 7
(1)
, Article 108. 10.1186/s13073-015-0233-4.
|
|
|
Teschendorff, AE;
Liu, X;
Caren, H;
Pollard, SM;
Beck, S;
Widschwendter, M;
Chen, L;
(2014)
The dynamics of DNA methylation covariation patterns in carcinogenesis.
PLoS Comput Biol
, 10
(7)
, Article e1003709. 10.1371/journal.pcbi.1003709.
|
|
|
Teschendorff, AE;
Marabita, F;
Lechner, M;
Bartlett, T;
Tegner, J;
Gomez-Cabrero, D;
Beck, S;
(2013)
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data.
Bioinformatics
, 29
(2)
189 - 196.
10.1093/bioinformatics/bts680.
|
|
|
Teschendorff, AE;
Menon, U;
Gentry-Maharaj, A;
Ramus, SJ;
Gayther, SA;
Apostolidou, S;
Jones, A;
... Widschwendter, M; + view all
(2009)
An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer.
PLOS ONE
, 4
(12)
, Article e8274. 10.1371/journal.pone.0008274.
|
|
|
Teschendorff, AE;
West, J;
Beck, S;
(2013)
Age-associated epigenetic drift: implications, and a case of epigenetic thrift?
Human Molecular Genetics
, 22
(R1)
R7-R15.
10.1093/hmg/ddt375.
|
|
|
Teschendorff, AE;
Zheng, SC;
Feber, A;
Yang, Z;
Beck, S;
Widschwendter, M;
(2016)
The multi-omic landscape of transcription factor inactivation in cancer.
Genome Medicine
, 8
, Article 89. 10.1186/s13073-016-0342-8.
|
|
|
Teschendorff, AE;
Zhu, T;
Breeze, CE;
Beck, S;
(2020)
EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data.
Genome Biology
, 21
, Article 221. 10.1186/s13059-020-02126-9.
|
|
|
Thanki, AS;
Soranzo, N;
Herrero, J;
Haerty, W;
Davey, RP;
(2018)
Aequatus: An open-source homology browser.
Gigascience
, 7
(11)
, Article giy128. 10.1093/gigascience/giy128.
|
|
|
Theobald, Sebastian J;
Simonis, Alexander;
Mudler, Julie M;
Goebel, Ulrike;
Acton, Richard;
Kohlhas, Viktoria;
Albert, Marie-Christine;
... Rybniker, Jan; + view all
(2022)
Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination.
EMBO Molecular Medicine
, 14
(8)
, Article e15888. 10.15252/emmm.202215888.
|
|
Thurner, M;
van de Bunt, M;
Torres, JM;
Mahajan, A;
Nylander, V;
Bennett, AJ;
Gaulton, KJ;
... McCarthy, MI; + view all
(2018)
Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci.
eLife
, 7
, Article e31977. 10.7554/eLife.31977.
|
|
|
Tian, Y;
Morris, TJ;
Webster, AP;
Yang, Z;
Beck, S;
Feber, A;
Teschendorff, AE;
(2017)
ChAMP: Updated Methylation Analysis Pipeline for Illumina BeadChips.
Bioinformatics
, 33
(24)
pp. 3982-3984.
10.1093/bioinformatics/btx513.
|
|
|
Tibarewal, Priyanka;
Rathbone, Victoria;
Conduit, Sarah E;
Classen, Gala Anastasia Electra;
Black, Fiona;
Danesh, Mohammad Amin;
Constantinou, Georgia;
... Vanhaesebroeck, Bart; + view all
(2025)
Impaired nuclear PTEN function drives macrocephaly, lymphadenopathy and late-onset cancer in PTEN Hamartoma Tumour Syndrome.
Disease Models & Mechanisms
, Article dmm.052527. 10.1242/dmm.052527.
(In press).
|
|
|
Tie, CH;
Fernandes, L;
Conde, L;
Robbez-Masson, L;
Sumner, RP;
Peacock, T;
Rodriguez-Plata, MT;
... Rowe, HM; + view all
(2018)
KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control.
EMBO Reports
, 19
(10)
, Article e45000. 10.15252/embr.201745000.
|
|
|
Tomazou, EM;
Rakyan, VK;
Lefebvre, G;
Andrews, R;
Ellis, P;
Jackson, DK;
Langford, C;
... Beck, S; + view all
(2008)
Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis.
BMC Medical Genomics
, 1
, Article 19. 10.1186/1755-8794-1-19.
|
 |
|
Tomita, K;
Cooper, JP;
(2008)
Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller.
Genes and Developement
, 22
(24)
3461 - 3474.
10.1101/gad.498608.
|
|
Tomita, K;
(2018)
How long does telomerase extend telomeres? Regulation of telomerase release and telomere length homeostasis.
Current Genetics
, 64
(6)
pp. 1177-1181.
10.1007/s00294-018-0836-6.
|
|
Tomkiewicz, Tomasz Z;
Suarez-Herrera, Nuria;
Cremers, Frans PM;
Collin, Rob WJ;
Garanto, Alejandro;
(2021)
Antisense Oligonucleotide-Based Rescue of Aberrant Splicing Defects Caused by 15 Pathogenic Variants in ABCA4.
International Journal of Molecular Sciences
, 22
(9)
, Article 4621. 10.3390/ijms22094621.
|
|
|
Touati, SA;
Kataria, M;
Jones, AW;
Snijders, AP;
Uhlmann, F;
(2018)
Phosphoproteome dynamics during mitotic exit in budding yeast.
EMBO Journal
, 37
(10)
, Article e98745. 10.15252/embj.201798745.
|
|
|
Traherne, JA;
Horton, R;
Roberts, AN;
Miretti, M;
Hurles, ME;
Stewart, CA;
Ashurst, JL;
... Beck, S; + view all
(2006)
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.
PLOS GENET
, 2
(1)
, Article e9. 10.1371/journal.pgen.0020009.
|
|
|
Trichas, G;
Joyce, B;
Crompton, LA;
Wilkins, V;
Clements, M;
Tada, M;
Rodriguez, TA;
(2011)
Nodal Dependent Differential Localisation of Dishevelled-2 Demarcates Regions of Differing Cell Behaviour in the Visceral Endoderm.
PLoS Biology
, 9
(2)
, Article e1001019. 10.1371/journal.pbio.1001019.
|
|
|
Tsuzuki, S;
Hong, DL;
Gupta, R;
Matsuo, K;
Seto, M;
Enver, T;
(2007)
Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1.
PLoS Medicine
, 4
(5)
, Article e172. 10.1371/journal.pmed.0040172.
|
|
|
Tsuzuki, S;
Seto, M;
Hong, D;
Gupta, R;
Enver, T;
Matsuo, K;
(2007)
Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1.
PLoS Medicine
, 4
(5)
, Article e172. 10.1371/journal.pmed.0040172.
|
|
|
Tummala, H;
Collopy, LC;
Walne, AJ;
Ellison, A;
Cardoso, S;
Aksu, T;
Yarali, N;
... Dokal, I; + view all
(2018)
Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita like phenotypes.
Blood
, 132
(12)
pp. 1349-1353.
10.1182/blood-2018-03-837799.
|
|
Turajlic, S;
Xu, H;
Litchfield, K;
Rowan, A;
Horswell, S;
Chambers, T;
O'Brien, T;
... TRACERx Renal Consortium, .; + view all
(2018)
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.
Cell
, 173
(3)
595-610.e11.
10.1016/j.cell.2018.03.043.
|
|
|
Turati, VA;
Guerra-Assunção, JA;
Potter, NE;
Gupta, R;
Ecker, S;
Daneviciute, A;
Tarabichi, M;
... Enver, T; + view all
(2021)
Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.
Nature Cancer
, 2
pp. 835-852.
10.1038/s43018-021-00219-3.
|
U
|
Uuskula-Reimand, L;
Hou, H;
Samavarchi-Tehrani, P;
Rudan, MV;
Liang, M;
Medina-Rivera, A;
Mohammed, H;
... Wilson, MD; + view all
(2016)
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders.
Genome Biology
, 17
, Article 182. 10.1186/s13059-016-1043-8.
|
V
|
Valdez Capuccino, L;
Kleitke, T;
Szokol, B;
Svajda, L;
Martin, F;
Bonechi, F;
Kreko, M;
... Peltzer, N; + view all
(2024)
CDK9 inhibition as an effective therapy for small cell
lung cancer.
Cell Death and Disease
, 15
, Article 345. 10.1038/s41419-024-06724-4.
|
|
Van Dongen, J;
Nivard, MG;
Willemsen, G;
Hottenga, JJ;
Helmer, Q;
Dolan, CV;
Ehli, EA;
... Boomsma, DI; + view all
(2016)
Genetic and environmental influences interact with age and sex in shaping the human methylome.
Nature Communications
, 7
, Article 11115. 10.1038/ncomms11115.
|
|
|
Vargas, FA;
Furness, AJS;
Litchfield, K;
Joshi, K;
Rosenthal, R;
Ghorani, E;
Solomon, I;
... Quezada, SA; + view all
(2018)
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer Cell
, 33
(4)
pp. 649-663.
10.1016/j.ccell.2018.02.010.
|
|
|
Vargas, FA;
Furness, AJS;
Solomon, I;
Joshi, K;
Mekkaoui, L;
Lesko, MH;
Rota, EM;
... Quezada, SA; + view all
(2017)
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.
Immunity
, 46
(4)
pp. 577-586.
10.1016/j.immuni.2017.03.013.
|
|
|
Varsally, W;
Hadjur, S;
(2018)
Capturing Complex Enhancer Regulatory Hubs? Try Tri-C.
[Editorial comment].
Developmental Cell
, 47
(5)
pp. 543-544.
10.1016/j.devcel.2018.11.021.
|
|
Veli, Ö;
Kaya, Ö;
Varanda, AB;
Hildebrandt, X;
Xiao, P;
Estornes, Y;
Poggenberg, M;
... Peltzer, N; + view all
(2024)
RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia.
Molecular Metabolism
, 87
, Article 101988. 10.1016/j.molmet.2024.101988.
|
|
Vesely, Clare;
Wong, Yien Ning Sophia;
Childs, Alexa;
Akarca, Ayse U;
Dhami, Pawan;
Vaikkinen, Heli;
Conde, Lucia;
... Meyer, Tim; + view all
(2022)
Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumours.
Clinical Cancer Research
10.1158/1078-0432.CCR-21-4203.
(In press).
|
|
|
Veturi, Yoga Advaith;
Woof, William;
Lazebnik, Teddy;
Moghul, Ismail;
Woodward-Court, Peter;
Wagner, Siegfried K;
Cabral de Guimarães, Thales Antonio;
... Pontikos, Nikolas; + view all
(2023)
SynthEye: Investigating the Impact of Synthetic Data on Artificial Intelligence-assisted Gene Diagnosis of Inherited Retinal Disease.
Ophthalmology Science
, 3
(2)
, Article 100258. 10.1016/j.xops.2022.100258.
|
|
Vila De Mucha, Maria Antonieta;
(2021)
Transcriptional regulation of tumour infiltrating cytotoxic CD4+ T cell differentiation.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Villegas-Mendez, A;
Khandelwal, G;
McGowan, LM;
Dookie, RS;
Haley, MJ;
George, C;
Sims, D;
... Couper, KN; + view all
(2020)
Exhausted CD4⁺ T Cells during Malaria Exhibit Reduced mTORc1 Activity Correlated with Loss of T-bet Expression.
The Journal of Immunology
, 205
(6)
pp. 1608-1619.
10.4049/jimmunol.2000450.
|
|
Vlachogiannis, G;
(2013)
Investigation of unique dependencies of cells lacking the PTEN tumour suppressor gene.
Doctoral thesis , UCL (University College London).
|
|
Vlachogiannis, G;
Niederhuth, CE;
Tuna, S;
Stathopoulou, A;
Viiri, K;
de Rooij, DG;
Jenner, RG;
... Ooi, SK; + view all
(2015)
The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis.
Cell Rep
, 10
(6)
pp. 944-956.
10.1016/j.celrep.2015.01.021.
|
|
Voersmann, H;
Groeber, F;
Walles, H;
Busch, S;
Beissert, S;
Walczak, H;
Kulms, D;
(2013)
Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing.
Cell Death and Disease
, 4
, Article e719. 10.1038/cddis.2013.249.
|
|
|
Vohringer, Harald S;
Sanderson, Theo;
Sinnott, Matthew;
De Maio, Nicola;
Thuy, Nguyen;
Goater, Richard;
Schwach, Frank;
... Gerstung, Moritz; + view all
(2021)
Genomic reconstruction of the SARS-CoV-2 epidemic in England.
Nature
, 600
(7889)
pp. 506-511.
10.1038/s41586-021-04069-y.
|
|
von Karstedt, S;
Montinaro, A;
Walczak, H;
(2017)
Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy.
Nature Reviews Cancer
, 17
(6)
pp. 352-366.
10.1038/nrc.2017.28.
|
|
|
von Karstedt, S;
Walczak, H;
(2020)
An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer.
Cell Death Discovery
, 6
, Article 14. 10.1038/s41420-020-0249-4.
|
|
|
Vukovic, Miodrag;
Tanic, Miljana;
Damjanovic, Ana;
Pavlovic, Marijana;
Stanojevic, Aleksandra;
Zivic, Katarina;
Karadzic, Valentina;
... Cavic, Milena; + view all
(2023)
EGFR mutation testing from pleural effusions of non-small cell lung cancer patients at the institute for oncology and radiology of Serbia.
Translational Oncology
, 37
, Article 101772. 10.1016/j.tranon.2023.101772.
|
|
W
|
Walczak, H;
Iwai, K;
Dikic, I;
(2012)
Generation and physiological roles of linear ubiquitin chains.
BMC Biology
, 10
, Article 23. 10.1186/1741-7007-10-23.
|
|
|
Wall, RJ;
Ferguson, DJP;
Freville, A;
Franke-Fayard, B;
Brady, D;
Zeeshan, M;
Bottrill, AR;
... Tewari, R; + view all
(2018)
Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.
Scientific Reports
, 8
, Article 5610. 10.1038/s41598-018-23871-9.
|
|
|
Wang, Y;
Karlsson, R;
Lampa, E;
Zhang, Q;
Hedman, ÅK;
Almgren, M;
Almqvist, C;
... Hägg, S; + view all
(2018)
Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins.
Epigenetics
10.1080/15592294.2018.1526028.
|
|
|
Watt, S;
Mata, J;
Lopez-Maury, L;
Marguerat, S;
Burns, G;
Bahler, J;
(2008)
urg1: A Uracil-Regulatable Promoter System for Fission Yeast with Short Induction and Repression Times.
PLOS ONE
, 3
(1)
, Article e1428. 10.1371/journal.pone.0001428.
|
|
|
Watt, S;
Vasquez, L;
Walter, K;
Mann, AL;
Kundu, K;
Chen, L;
Sims, Y;
... Soranzo, N; + view all
(2021)
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.
Nature Communications
, 12
, Article 2298. 10.1038/s41467-021-22548-8.
|
|
|
Webster, Amy P;
Ecker, Simone;
Moghul, Ismail;
Dhami, Pawan;
Marzi, Sarah;
Paul, Dirk S;
Kuxhausen, Michelle;
... Beck, Stephan; + view all
(2022)
Donor whole blood DNA methylation is not a strong predictor of acute graft versus host disease in unrelated donor allogeneic haematopoietic cell transplantation.
medRxiv
10.1101/2022.03.08.22272071.
(In press).
|
|
|
Webster, AP;
Plant, D;
Ecker, S;
Zufferey, F;
Bell, JT;
Feber, A;
Paul, DS;
... Worthington, J; + view all
(2018)
Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins.
Genome Medicine
, 10
(1)
, Article 64. 10.1186/s13073-018-0575-9.
|
|
|
Weeks, Samuel Luke;
(2022)
Characterisation of the roles of Stag paralogs in transitions of pluripotency.
Doctoral thesis (Ph.D), UCL (University College London).
|
|
Werdehausen, R;
Mittnacht, S;
McLaughlin, LA;
Minett, MS;
Armbruster, A;
Bauer, I;
Wood, JN;
... Eulenburg, V; + view all
(2015)
The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain.
PAIN
, 156
(9)
pp. 1647-1659.
10.1097/j.pain.0000000000000206.
|
|
West, J;
Beck, S;
Wang, X;
Teschendorff, AE;
(2013)
An integrative network algorithm identifies age-associated differential methylation interactome hotspots targeting stem-cell differentiation pathways.
Scientific Reports
, 3
, Article 1630. 10.1038/srep01630.
|
|
|
Widayati, Tyas Arum;
Schneider, Jadesada;
Panteleeva, Kseniia;
Chernysheva, Elizabeth;
Hrbkova, Natalie;
Beck, Stephan;
Voloshin, Vitaly;
(2023)
Open access-enabled evaluation of epigenetic age acceleration in colorectal cancer and development of a classifier with diagnostic potential.
Frontiers in Genetics
, 14
, Article 1258648. 10.3389/fgene.2023.1258648.
|
|
|
Willms, A;
Schupp, H;
Poelker, M;
Adawy, A;
Debus, JF;
Hartwig, T;
Krichel, T;
... Trauzold, A; + view all
(2021)
TRAIL-receptor 2-a novel negative regulator of p53.
Cell Death & Disease
, 12
(8)
, Article 757. 10.1038/s41419-021-04048-1.
|
|
|
Wilson, GA;
Butcher, LM;
Foster, HR;
Feber, A;
Roos, C;
Walter, L;
Woszczek, G;
... Bell, CG; + view all
(2014)
Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases.
Genome Med
, 6
(3)
, Article 19. 10.1186/gm536.
|
|
|
Wilson, GA;
Lechner, M;
Köferle, A;
Carén, H;
Butcher, LM;
Feber, A;
Fenton, T;
... Beck, S; + view all
(2013)
Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.
Epigenetics
, 8
(9)
pp. 953-961.
10.4161/epi.25614.
|
|
|
Wong, DCS;
Olivera, M;
Yu, J;
Szabo, A;
Moghul, I;
Balaskas, KS;
Luben, R;
... Keane, PA; + view all
(2021)
Cloud-based genomics pipelines for ophthalmology: Reviewed from research to clinical practice.
Journal for Modeling in Ophthalmology
, 3
(1)
pp. 101-140.
10.35119/maio.v3i1.115.
|
|
|
Woods, Angela;
Heslegrave, Amanda J;
Muckett, Phillip J;
Levene, Adam P;
Clements, Melanie;
Mobberley, Margaret;
Ryder, Timothy A;
... Carling, David; + view all
(2011)
LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice.
Biochemical Journal
, 434
(1)
pp. 49-60.
10.1042/BJ20101721.
|
|
Worley, KC;
Warren, WC;
Rogers, J;
Locke, D;
Muzny, DM;
Mardis, ER;
Weinstock, GM;
... Wilson, RK; + view all
(2014)
The common marmoset genome provides insight into primate biology and evolution.
Nature Genetics
, 46
(8)
pp. 850-857.
10.1038/ng.3042.
|
|
|
Wray, Jason P;
Deltcheva, Elitza M;
Boiers, Charlotta;
Richardson, Simon Е;
Chhetri, Jyoti Bikram;
Brown, John;
Gagrica, Sladjana;
... Enver, Tariq; + view all
(2022)
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability.
Nature Communications
, 13
, Article 7124. 10.1038/s41467-022-34653-3.
|
Y
|
Yamano, H;
(2019)
APC/C: current understanding and future perspectives.
F1000Research
, 8
, Article 725. 10.12688/f1000research.18582.1.
|
|
|
Yanez-Guerra, LA;
Zhong, X;
Moghul, I;
Butts, T;
Zampronio, CG;
Jones, AM;
Mirabeau, O;
(2020)
Echinoderms provide missing link in the evolution of PrRP/sNPF-type neuropeptide signalling.
eLife
, 9
, Article e57640. 10.7554/eLife.57640.
|
|
|
Yang, Z;
Wong, A;
Kuh, D;
Paul, DS;
Rakyan, VK;
Leslie, RD;
Zheng, SC;
... Teschendorff, AE; + view all
(2016)
Correlation of an epigenetic mitotic clock with cancer risk.
GENOME BIOLOGY
, 17
(ARTN 205)
10.1186/s13059-016-1064-3.
|
|
|
Yogev, O;
Henderson, S;
Hayes, MJ;
Marelli, SS;
Ofir-Birin, Y;
Regev-Rudzki, N;
Herrero, J;
(2017)
Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs.
PLoS Pathogens
, 13
(8)
, Article e1006524. 10.1371/journal.ppat.1006524.
|
|
|
Yogev, O;
Lagos, D;
Enver, T;
Boshoff, C;
(2014)
Kaposi's Sarcoma Herpesvirus MicroRNAs Induce Metabolic Transformation of Infected Cells.
PLoS Pathog
, 10
(9)
, Article e1004400 . 10.1371/journal.ppat.1004400.
|
|
|
Young, LC;
(2016)
Regulation of the RAS-ERK pathway by SHOC2.
Doctoral thesis , UCL (University College London).
|
|
Young, LC;
Hartig, N;
del Rio, IB;
Sari, S;
Ringham-Terry, B;
Wainwright, JR;
Jones, GG;
... Rodriguez-Viciana, P; + view all
(2018)
SHOC2-MRAS-PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis.
Proceedings of the National Academy of Sciences of the United States of America
, 115
(45)
E10576-E10585.
10.1073/pnas.1720352115.
|
|
|
Young, LC;
Rodriguez-Viciana, P;
(2018)
MRAS: A Close but Understudied Member of the RAS Family.
Cold Spring Harb Perspect Med
10.1101/cshperspect.a033621.
(In press).
|
|
|
Youssef, G;
(2016)
Mechanisms of Hyperkeratosis in Autosomal Recessive Congenital Ichthyosis (ARCI).
Doctoral thesis , UCL (University College London).
|
|
Yuan, G-C;
Cai, L;
Elowitz, M;
Enver, T;
Fan, G;
Guo, G;
Irizarry, R;
... Tirosh, I; + view all
(2017)
Challenges and emerging directions in single-cell analysis.
Genome Biology
, 18
, Article 84. 10.1186/s13059-017-1218-y.
|
|
|
Yue, F;
Cheng, Y;
Breschi, A;
Vierstra, J;
Wu, W;
Ryba, T;
Sandstrom, R;
... Ren, B; + view all
(2014)
A comparative encyclopedia of DNA elements in the mouse genome.
Nature
, 515
(7527)
pp. 355-364.
10.1038/nature13992.
|
|
Z
|
Zhang, Xiaoyan;
Yang, Ling;
Lei, Wanjun;
Hou, Qiang;
Huang, Ming;
Zhou, Rongjing;
Enver, Tariq;
(2022)
Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer.
EBioMedicine
, 82
, Article 104125. 10.1016/j.ebiom.2022.104125.
|
|
Zhang, C;
Stockwell, SR;
Elbanna, M;
Ketteler, R;
Freeman, J;
Al-Lazikani, B;
Eccles, S;
... Mittnacht, S; + view all
(2019)
Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.
Oncogene
, 38
pp. 5905-5920.
10.1038/s41388-019-0850-2.
|
|
Zhang, J;
Riby, JE;
Conde, L;
Grizzle, WE;
Cui, X;
Skibola, CF;
(2016)
A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines.
BMC Complement Altern Med
, 16
p. 151.
10.1186/s12906-016-1129-6.
|
|
Zheng, S;
Breeze, C;
Beck, S;
Teschendorff, AE;
(2018)
Identification of differentially methylated cell types in epigenome-wide association studies.
Nature Methods
, 15
1059 -1066.
10.1038/s41592-018-0213-x.
|
|
Zheng, SC;
Beck, S;
Jaffe, AE;
Koestler, DC;
Hansen, KD;
Houseman, AE;
Irizarry, RA;
(2017)
Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses.
Nature Methods
, 14
(3)
pp. 216-217.
10.1038/nmeth.4187.
|
|
Zheng, SC;
Breeze, CE;
Beck, S;
Dong, D;
Zhu, T;
Ma, L;
Ye, W;
... Teschendorff, AE; + view all
(2020)
EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI.
Bioinformatics
, 36
(6)
pp. 1950-1951.
10.1093/bioinformatics/btz833.
|
|
|
Zheng, SC;
Webster, AP;
Dong, D;
Feber, A;
Graham, DG;
Sullivan, R;
Jevons, S;
... Teschendorff, AE; + view all
(2018)
A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix.
Epigenomics
, 10
(7)
pp. 925-940.
10.2217/epi-2018-0037.
|
|
Zhou, L;
Lyons-Rimmer, J;
Ammoun, S;
Müller, J;
Lasonder, E;
Sharma, V;
Ercolano, E;
... Hanemann, CO; + view all
(2016)
The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.
Oncogene
, 35
pp. 3443-3453.
10.1038/onc.2015.404.
|
|
|
Zhou, L;
Ng, HK;
Drautz-Moses, DI;
Schuster, SC;
Beck, S;
Kim, C;
Chambers, JC;
(2019)
Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing.
Scientific Reports
, 9
, Article 10383. 10.1038/s41598-019-46875-5.
|
|
|
Zhu, Tianyu;
Liu, Jacklyn;
Beck, Stephan;
Pan, Sun;
Capper, David;
Lechner, Matt;
Thirlwell, Chrissie;
... Teschendorff, Andrew E; + view all
(2022)
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution.
Nature Methods
, 19
pp. 296-306.
10.1038/s41592-022-01412-7.
|
|
Zierhut, C.;
(2007)
The involvement of single-stranded DNA, replication protein A, and the DNA double-strand break dose in the damage checkpoint of Saccharomyces cerevisiae.
Doctoral thesis , University of London.
|
|
|
Zinngrebe, Julia;
Moepps, Barbara;
Monecke, Thomas;
Gierschik, Peter;
Schlichtig, Ferdinand;
Barth, Thomas FE;
Strauß, Gudrun;
... Debatin, Klaus-Michael; + view all
(2022)
Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS.
EMBO Molecular Medicine
, 14
(3)
, Article e14901. 10.15252/emmm.202114901.
|
|
Zinngrebe, J;
Montinaro, A;
Peltzer, N;
Walczak, H;
(2014)
Ubiquitin in the immune system.
EMBO Rep
, 15
(1)
pp. 28-45.
10.1002/embr.201338025.
|
|
|
Zinngrebe, J;
Rieser, E;
Taraborrelli, L;
Peltzer, N;
Hartwig, T;
Ren, H;
Kovacs, I;
... Walczak, H; + view all
(2016)
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation.
Journal of Experimental Medicine
, 213
(12)
pp. 2671-2689.
10.1084/jem.20160041.
|
|
Zinngrebe, J;
Walczak, H;
(2017)
TLRs Go Linear – On the Ubiquitin Edge.
Trends in Molecular Medicine
, 23
(4)
pp. 296-309.
10.1016/j.molmed.2017.02.003.
|
   |
|
Znati, S;
Carter, R;
Vasquez, M;
Westhorpe, A;
Shahbakhti, H;
Prince, J;
Vlckova, P;
... Sharma, RA; + view all
(2020)
Radiosensitisation of Hepatocellular Carcinoma Cells by Vandetanib.
Cancers
, 12
(7)
, Article 1878. 10.3390/cancers12071878.
|
|
Zoumpoulidou, G;
Alvarez-Mendoza, C;
Mancusi, C;
Ahmed, R-M;
Denman, M;
Steele, CD;
Tarabichi, M;
... Mittnacht, S; + view all
(2021)
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma.
Nature Communications
, 12
(1)
, Article 7064. 10.1038/s41467-021-27291-8.
|
|
Ś
|
Śledzińska, A;
Vila de Mucha, M;
Bergerhoff, K;
Hotblack, A;
Demane, DF;
Ghorani, E;
Akarca, AU;
... Quezada, SA; + view all
(2020)
Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.
Immunity
, 52
(1)
151-166.e6.
10.1016/j.immuni.2019.12.007.
|
