UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data.

Morris, TJ; Beck, S; (2015) Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data. Methods , 72 3 - 8. 10.1016/j.ymeth.2014.08.011. Green open access

[thumbnail of 1-s2.0-S1046202314002692-main.pdf] PDF
1-s2.0-S1046202314002692-main.pdf

Download (634kB)

Abstract

The Illumina HumanMethylation450 BeadChip has become a popular platform for interrogating DNA methylation in epigenome-wide association studies (EWAS) and related projects as well as resource efforts such as the International Cancer Genome Consortium (ICGC) and the International Human Epigenome Consortium (IHEC). This has resulted in an exponential increase of 450k data in recent years and triggered the development of numerous integrated analysis pipelines and stand-alone packages. This review will introduce and discuss the currently most popular pipelines and packages and is particularly aimed at new 450k users.

Type: Article
Title: Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ymeth.2014.08.011
Publisher version: http://dx.doi.org/10.1016/j.ymeth.2014.08.011
Language: English
Additional information: Copyright © 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
Keywords: 450k BeadChip, Analysis pipelines, DNA methylation, EWAS, Epigenetics, HumanMethylation450
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio
URI: https://discovery.ucl.ac.uk/id/eprint/1450650
Downloads since deposit
312Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item