UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

ChAMP: Updated Methylation Analysis Pipeline for Illumina BeadChips

Tian, Y; Morris, TJ; Webster, AP; Yang, Z; Beck, S; Feber, A; Teschendorff, AE; (2017) ChAMP: Updated Methylation Analysis Pipeline for Illumina BeadChips. Bioinformatics , 33 (24) pp. 3982-3984. 10.1093/bioinformatics/btx513. Green open access

[thumbnail of Beck_btx513.pdf]
Preview
Text
Beck_btx513.pdf - Published Version

Download (174kB) | Preview

Abstract

Summary: The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput DNA methylation analysis, effectively doubling the coverage compared to the older 450 K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including correction for cell-type heterogeneity, network analysis and a series of interactive graphical user interfaces. / Availability and implementation: ChAMP is a BioC package available from https://bioconductor.org/packages/release/bioc/html/ChAMP.html. / Contact: a.teschendorff@ucl.ac.uk or s.beck@ucl.ac.uk or a.feber@ucl.ac.uk / Supplementary information: Supplementary data are available at Bioinformatics online.

Type: Article
Title: ChAMP: Updated Methylation Analysis Pipeline for Illumina BeadChips
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/bioinformatics/btx513
Publisher version: https://doi.org/10.1093/bioinformatics/btx513
Language: English
Additional information: Copyright © The Author 2017. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/10024459
Downloads since deposit
104Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item