Bertaux, François;
Kleijn, Istvan T;
Marguerat, Samuel;
Shahrezaei, Vahid;
(2023)
Fission yeast obeys a linear size law under nutrient titration.
microPublication Biology
, 2023
10.17912/micropub.biology.000833.
Preview |
Text
micropub-biology-000833.pdf - Published Version Download (528kB) | Preview |
Abstract
Steady-state cell size and geometry depend on growth conditions. Here, we use an experimental setup based on continuous culture and single-cell imaging to study how cell volume, length, width and surface-to-volume ratio vary across a range of growth conditions including nitrogen and carbon titration, the choice of nitrogen source, and translation inhibition. Overall, we find cell geometry is not fully determined by growth rate and depends on the specific mode of growth rate modulation. However, under nitrogen and carbon titrations, we observe that the cell volume and the growth rate follow the same linear scaling.
| Type: | Article |
|---|---|
| Title: | Fission yeast obeys a linear size law under nutrient titration |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.17912/micropub.biology.000833 |
| Publisher version: | http://doi.org/10.17912/micropub.biology.000833 |
| Language: | English |
| Additional information: | © 2023 by the authors. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10185808 |
Archive Staff Only
 |
View Item |
