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Number of items: 125.
Article
Asghar, US;
Kanani, R;
Roylance, R;
Mittnacht, S;
(2022)
Systematic Review of Molecular Biomarkers Predictive of Resistance to CDK4/6 Inhibition in Metastatic Breast Cancer.
JCO Precision Oncology
, 6
pp. 1-13.
10.1200/po.21.00002.
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Atsamnia, Djamel;
Hanini, Salah;
Oukrif, Dahmane;
Benachour, Karine;
Benkortbi, Othmane;
Hamadache, Mabrouk;
(2022)
Comparative Therapeutic Properties of Garlic Extract and Metformin on Hyperglycaemia, Hypercholesterolaemia, and Hypertriglyceridaemia in Alloxan-induced Type1-like Diabetic Rats.
Kemija u Industriji
, 71
(3-4)
pp. 141-149.
10.15255/kui.2021.035.
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Beaton, Laura;
Tregidgo, Henry Fj;
Znati, Sami A;
Forsyth, Sharon;
Counsell, Nicholas;
Clarkson, Matthew J;
Bandula, Steven;
... Sharma, Ricky A; + view all
(2022)
Phase 0 study of vandetanib-eluting radiopaque embolics as a pre-operative embolization treatment in patients with resectable liver malignancies.
Journal of Vascular and Interventional Radiology
10.1016/j.jvir.2022.04.033.
(In press).
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Bennett, Clare;
(2022)
Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages.
Cell Reports
, 39
(7)
, Article 110819. 10.1016/j.celrep.2022.110819.
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Bergstrom, Erik N;
Luebeck, Jens;
Petljak, Mia;
Khandekar, Azhar;
Barnes, Mark;
Zhang, Tongwu;
Steele, Christopher D;
... Alexandrov, Ludmil B; + view all
(2022)
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA.
Nature
10.1038/s41586-022-04398-6.
(In press).
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Best, Jonathan G;
Arram, Liz;
Ahmed, Norin;
Balogun, Maryam;
Bennett, Kate;
Bordea, Ekaterina;
Campos, Marta G;
... OPTIMAS investigators, .; + view all
(2022)
Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial.
International Journal of Stroke
10.1177/17474930211057722.
(In press).
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Bolik, J;
Krause, F;
Stevanovic, M;
Gandraß, M;
Thomsen, I;
Schacht, S-S;
Rieser, E;
... Schmidt-Arras, D; + view all
(2022)
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
J Exp Med
, 219
(1)
, Article e20201039. 10.1084/jem.20201039.
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Bowes, Amy;
Tarabichi, Maxime;
Pillay, Nischalan;
Van Loo, Peter;
(2022)
Leveraging single cell sequencing to unravel intra-tumour heterogeneity and tumour evolution in human cancers.
Journal of Pathology
10.1002/path.5914.
(In press).
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Breeze, CE;
Haugen, E;
Reynolds, A;
Teschendorff, A;
van Dongen, J;
Lan, Q;
Rothman, N;
... Berndt, SI; + view all
(2022)
Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations.
Genome Biololgy
, 23
(1)
, Article 13. 10.1186/s13059-021-02560-3.
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Bridgewater, John;
Fletcher, Peter;
Palmer, Daniel H;
Malik, Hassan Z;
Prasad, Raj;
Mirza, Darius;
Anthony, Alan;
... BILCAP study group, .; + view all
(2022)
Long-Term Outcomes and Exploratory Analyses of the Randomized Phase III BILCAP Study.
Journal of Clinical Oncology
, Article JCO2102568. 10.1200/JCO.21.02568.
(In press).
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Brimble, MA;
Cheng, PH;
Winston, SM;
Reeves, IL;
Souquette, A;
Spence, Y;
Zhou, J;
... Davidoff, AM; + view all
(2022)
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps.
Molecular Therapy - Methods and Clinical Development
, 24
pp. 280-291.
10.1016/j.omtm.2022.01.008.
(In press).
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Brown, Sarah R;
Hinsley, Samantha;
Hall, Emma;
Hurt, Chris;
Baird, Richard D;
Forster, Martin;
Scarsbrook, Andrew F;
(2022)
A Road Map for Designing Phase I Clinical Trials of Radiotherapy–Novel Agent Combinations.
Clinical Cancer Research
10.1158/1078-0432.CCR-21-4087.
(In press).
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Camilleri, Marquita;
Bekris, Georgios;
Sidhu, Govundeep;
Buck, Caroline;
Elsden, Esma;
McCourt, Orla;
Horder, Jackie;
... Fisher, Abigail; + view all
(2022)
The impact of COVID-19 on autologous stem cell transplantation in multiple myeloma: A single-centre, qualitative evaluation study.
Supportive Care in Cancer
10.1007/s00520-022-07173-5.
(In press).
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Cardenas, Andres;
Ecker, Simone;
Fadadu, Raj P;
Huen, Karen;
Orozco, Allan;
McEwen, Lisa M;
Engelbrecht, Hannah-Ruth;
... Rehkopf, David H; + view all
(2022)
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults.
Scientific Reports
, 12
, Article 4277. 10.1038/s41598-022-08160-w.
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Casali, PG;
Blay, JY;
Abecassis, N;
Bajpai, J;
Bauer, S;
Biagini, R;
Bielack, S;
... Stacchiotti, S; + view all
(2022)
Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 33
(1)
pp. 20-33.
10.1016/j.annonc.2021.09.005.
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Chan, WY;
Zhu, C;
Sanchez, E;
Gupta, R;
Fielding, AK;
Khwaja, A;
Payne, EM;
(2022)
Antibody responses to SARS-CoV-2 vaccination in patients with acute myeloid leukaemia and high risk MDS on active anti-cancer therapies.
British Journal of Haematology
10.1111/bjh.18248.
(In press).
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Cortellini, Alessio;
Gennari, Alessandra;
Pommeret, Fanny;
Patel, Grisma;
Newsom-Davis, Thomas;
Bertuzzi, Alexia;
Viladot, Margarita;
... OnCovid study group, .; + view all
(2022)
COVID-19 Sequelae and the Host Pro-Inflammatory Response: An Analysis From the OnCovid Registry.
JNCI: Journal of the National Cancer Institute
10.1093/jnci/djac057.
(In press).
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Cortellini, Alessio;
Salazar, Ramon;
Gennari, Alessandra;
Aguilar-Company, Juan;
Bower, Mark;
Bertuzzi, Alexia;
Brunet, Joan;
... Pinato, David J; + view all
(2022)
Persistence of long-term COVID-19 sequelae in patients with cancer: an analysis from the OnCovid registry.
European Journal of Cancer
, 170
pp. 10-16.
10.1016/j.ejca.2022.03.019.
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Day, James W;
Fox, Thomas A;
Gupta, Rajeev;
Khwaja, Asim;
Wilson, Andrew J;
Kottaridis, Panagiotis D;
(2022)
Gilteritinib monotherapy as a transplant bridging option for high risk FLT3-mutated AML with t(6;9)(p23;q34.1);DEK-NUP214 in morphological but not cytogenetic or molecular remission following standard induction chemotherapy.
Leukemia Research Reports
, 17
, Article 100291. 10.1016/j.lrr.2022.100291.
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Dinneen, E;
Allen, C;
Strange, T;
Heffernan-Ho, D;
Banjeglav, J;
Lindsay, J;
Mulligan, JP;
... Punwani, S; + view all
(2022)
Negative mpMRI Rules Out Extra-Prostatic Extension in Prostate Cancer before Robot-Assisted Radical Prostatectomy.
Diagnostics
, 12
(5)
, Article 1057. 10.3390/diagnostics12051057.
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Doki, Yuichiro;
Ajani, Jaffer A;
Kato, Ken;
Xu, Jianming;
Wyrwicz, Lucjan;
Motoyama, Satoru;
Ogata, Takashi;
... CheckMate 648 Trial Investigators; + view all
(2022)
Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma.
New England Journal of Medicine
, 386
(5)
pp. 449-462.
10.1056/NEJMoa2111380.
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Efthymiou, M;
Lane, PJ;
Isenberg, D;
Cohen, H;
Mackie, IJ;
(2022)
Comparison of acquired activated protein C resistance, using the CAT and ST-genesia® analysers and three thrombin generation methods, in APS and SLE patients.
Journal of Clinical Medicine
, 11
(1)
, Article 69. 10.3390/jcm11010069.
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El-Khoueiry, Anthony B;
Meyer, Tim;
Cheng, Ann-Lii;
Rimassa, Lorenza;
Sen, Suvajit;
Milwee, Steven;
Kelley, Robin Kate;
(2022)
Safety and efficacy of cabozantinib for patients with advanced hepatocellular carcinoma who advanced to Child-Pugh B liver function at study week 8: a retrospective analysis of the CELESTIAL randomised controlled trial.
BMC Cancer
, 22
, Article 377. 10.1186/s12885-022-09453-z.
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Elstein, D;
Belmatoug, N;
Deegan, P;
Göker-Alpan, Ö;
Hughes, DA;
Schwartz, IVD;
Weinreb, N;
... Zimran, A; + view all
(2022)
Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials.
Orphanet Journal of Rare Diseases
, 17
, Article 9. 10.1186/s13023-021-02163-y.
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Eschweiler, Simon;
Ramírez-Suástegui, Ciro;
Li, Yingcong;
King, Emma;
Chudley, Lindsey;
Thomas, Jaya;
Wood, Oliver;
... Ottensmeier, Christian H; + view all
(2022)
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Nature
10.1038/s41586-022-04685-2.
(In press).
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Evans, JA;
Carlotti, E;
Lin, M-L;
Hackett, RJ;
Haughey, MJ;
Passman, AM;
Dunn, L;
... McDonald, SA; + view all
(2022)
Clonal Transitions and Phenotypic Evolution in Barrett's Esophagus.
Gastroenterology
, 162
(4)
1197-1209.e13.
10.1053/j.gastro.2021.12.271.
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Freemantle, Nick;
Mollon, Patrick;
Meyer, Tim;
Cheng, Ann-Lii;
El-Khoueiry, Anthony B;
Kelley, Robin K;
Baron, Ari D;
... Abou-Alfa, Ghassan K; + view all
(2022)
Quality of life assessment of cabozantinib in patients with advanced hepatocellular carcinoma in the CELESTIAL trial.
European Journal of Cancer
, 168
pp. 91-98.
10.1016/j.ejca.2022.03.021.
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Gatenbee, CD;
Baker, AM;
Schenck, RO;
Strobl, M;
West, J;
Neves, MP;
Hasan, SY;
... Anderson, ARA; + view all
(2022)
Immunosuppressive niche engineering at the onset of human colorectal cancer.
Nature Communications
, 13
, Article 1798. 10.1038/s41467-022-29027-8.
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Geron, Ifat;
Savino, Angela Maria;
Fishman, Hila;
Tal, Noa;
Brown, John;
Turati, Virginia A;
James, Chela;
... Izraeli, Shai; + view all
(2022)
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
Nature Communications
, 13
, Article 659. 10.1038/s41467-022-28218-7.
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Gomez, V;
Galazi, M;
Weitsman, G;
Monypenny, J;
Al-Salemee, F;
Barber, P;
Ng, K;
... Ng, T; + view all
(2022)
HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models.
Molecular Cancer Therapeutics
, 21
(4)
pp. 667-676.
10.1158/1535-7163.MCT-21-0320.
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Green, HM;
Counsell, N;
Ward, A;
McCormack, M;
(2022)
Neoadjuvant Chemotherapy in Locally Advanced Cervical Carcinoma – a Role in Patients with Para-aortic Lymph Node Involvement? A 10-year Institutional Experience.
Clinical Oncology
10.1016/j.clon.2021.12.005.
(In press).
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Hackshaw, Allan;
Clarke, Christina A;
Hartman, Anne-Renee;
(2022)
New genomic technologies for multi-cancer early detection: Rethinking the scope of cancer screening.
Cancer Cell
10.1016/j.ccell.2022.01.012.
(In press).
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Hagos, Yeman B;
Akarca, Ayse U;
Ramsay, Alan;
Rossi, Riccardo L;
Pomplun, Sabine;
Ngai, Victoria;
Moioli, Alessia;
... Marafioti, Teresa; + view all
(2022)
High inter-follicular spatial co-localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma.
Hematological Oncology
10.1002/hon.3003.
(In press).
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Hames-Fathi, S;
Nottley, SWG;
Pillay, N;
(2022)
Unravelling undifferentiated soft tissue sarcomas: insights from genomics.
Histopathology
, 80
(1)
pp. 109-121.
10.1111/his.14446.
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Harrasser, Micaela;
Gohil, Satyen Harish;
Lau, Hiu;
Della Peruta, Marco;
Muczynski, Vincent;
Patel, Dominic;
Miranda, Elena;
... Nathwani, Amit Chunilal; + view all
(2022)
Inducible localized delivery of an anti-PD-1 scFv enhances anti-tumor activity of ROR1 CAR-T cells in TNBC.
Breast Cancer Research
, 24
(1)
, Article 39. 10.1186/s13058-022-01531-1.
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Helfen, A;
Rieß, J;
Fehler, O;
Stölting, M;
An, Z;
Kocman, V;
Schnepel, A;
... Eisenblätter, M; + view all
(2022)
In vivo imaging of microenvironmental and anti-PD-L1-mediated dynamics in cancer using S100A8/S100A9 as an imaging biomarker.
Neoplasia
, 28
, Article 100792. 10.1016/j.neo.2022.100792.
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Hertweck, Arnulf;
Vila de Mucha, Maria;
Barber, Paul R;
Dagil, Robert;
Porter, Hayley;
Ramos, Andres;
Lord, Graham M;
(2022)
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.
Nucleic Acids Research
, Article gkac258. 10.1093/nar/gkac258.
(In press).
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Holm, Jeppe Sejerø;
Funt, Samuel A;
Borch, Annie;
Munk, Kamilla Kjærgaard;
Bjerregaard, Anne-Mette;
Reading, James L;
Maher, Colleen;
... Hadrup, Sine Reker; + view all
(2022)
Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma.
Nature Communications
, 13
, Article 1935. 10.1038/s41467-022-29342-0.
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Horgan, D;
Borisch, B;
Cattaneo, I;
Caulfield, M;
Chiti, A;
Chomienne, C;
Cole, A;
... von Meyenn, M; + view all
(2022)
Factors Affecting Citizen Trust and Public Engagement Relating to the Generation and Use of Real-World Evidence in Healthcare.
International Journal of Environmental Research and Public Health
, 19
(3)
, Article 1674. 10.3390/ijerph19031674.
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Hough, R;
Lopes, A;
Patrick, P;
Russell, N;
Raj, K;
Tholouli, E;
Snowden, JA;
... Marks, D; + view all
(2022)
Primary graft failure, but not relapse, may be identified by early chimerism following double cord blood unit transplantation.
Blood Advances
, 6
(7)
pp. 2414-2426.
10.1182/bloodadvances.2021005106.
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Howell, Rowan;
Clarke, Matthew A;
Reuschl, Ann-Kathrin;
Chen, Tianyi;
Abbott-Imboden, Sean;
Singer, Mervyn;
Lowe, David M;
... Fisher, Jasmin; + view all
(2022)
Executable network of SARS-CoV-2-host interaction predicts drug combination treatments.
npj Digital Medicine
, 5
(1)
, Article 18. 10.1038/s41746-022-00561-5.
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Huerne, Katherine;
Palmour, Nicole;
Wu, Angela Ruohao;
Beck, Stephan;
Berner, Alison;
Siebert, Reiner;
Joly, Yann;
(2022)
Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing.
The CRISPR Journal
10.1089/crispr.2021.0094.
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Hughes, Derralynn A;
Aguiar, Patrício;
Lidove, Olivier;
Nicholls, Kathleen;
Nowak, Albina;
Thomas, Mark;
Torra, Roser;
... Feriozzi, Sandro; + view all
(2022)
Do clinical guidelines facilitate or impede drivers of treatment in Fabry disease?
Orphanet Journal of Rare Diseases
, 17
(1)
, Article 42. 10.1186/s13023-022-02181-4.
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Ingley, KM;
Maleddu, A;
Le Grange, F;
Gerrand, C;
Bleyer, A;
Yasmin, E;
Whelan, J;
(2022)
Current approaches to management of bone sarcoma in adolescent and young adult patients.
Pediatric Blood & Cancer
, 69
(2)
, Article e29442. 10.1002/pbc.29442.
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Kleijn, Istvan T;
Martínez-Segura, Amalia;
Bertaux, François;
Saint, Malika;
Kramer, Holger;
Shahrezaei, Vahid;
Marguerat, Samuel;
(2022)
Growth-rate-dependent and nutrient-specific gene expression resource allocation in fission yeast.
Life Science Alliance
, 5
(5)
, Article e202101223. 10.26508/lsa.202101223.
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Klemm, Cinzia;
Howell, Rowan SM;
Thorpe, Peter H;
(2022)
ScreenGarden: a shinyR application for fast and easy analysis of plate-based high-throughput screens.
BMC Bioinformatics
, 23
(1)
, Article 60. 10.1186/s12859-022-04586-1.
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Kos, K;
Aslam, MA;
van de Ven, R;
Wellenstein, MD;
Pieters, W;
van Weverwijk, A;
Duits, DEM;
... de Visser, KE; + view all
(2022)
Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche.
Cell Reports
, 38
(9)
, Article 110447. 10.1016/j.celrep.2022.110447.
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Kumar, Shankar;
Parry, Thomas;
Mallett, Sue;
Bhatnagar, Gauraang;
Plumb, Andrew;
Walsh, Shaun;
Scott, Nigel;
... Taylor, Stuart; + view all
(2022)
Diagnostic performance of magnetic resonance enterography disease activity indices compared with a histological reference standard for adult terminal ileal Crohn's disease: experience from the METRIC trial.
Journal of Crohn's and Colitis
10.1093/ecco-jcc/jjac062.
(In press).
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Lally, P;
Miller, N;
Roberts, A;
Beeken, RJ;
Greenfield, DM;
Potts, HWW;
Counsell, N;
... Fisher, A; + view all
(2022)
An app with brief behavioural support to promote physical activity after a cancer diagnosis (APPROACH): study protocol for a pilot randomised controlled trial.
Pilot and Feasibility Studies
, 8
(1)
, Article 74. 10.1186/s40814-022-01028-w.
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Land, Joanne;
Hackett, Julia;
Sidhu, Govundeep;
Heinrich, Malgorzata;
McCourt, Orla;
Yong, Kwee L;
Fisher, Abi;
(2022)
Myeloma patients' experiences of a supervised physical activity programme: a qualitative study.
Support Care Cancer
, 30
pp. 6273-6286.
10.1007/s00520-022-07062-x.
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Ledermann, JA;
(2022)
Testing for homologous recombination deficiency – does it provide new insights for the use of veliparib?
Gynecologic Oncology
, 164
(2)
pp. 243-244.
10.1016/j.ygyno.2022.01.018.
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Lee, DDH;
Cardinale, D;
Saman, Y;
Hirst, RA;
Wilson, N;
Corden, V;
Rutman, A;
... O'Callaghan, C; + view all
(2022)
COVID-19: Extensive epithelial damage and ciliary dyskinesia in hospitalised patients.
Rhinology
10.4193/Rhin21.233.
(In press).
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Lee, Lennard YW;
Starkey, Thomas;
Ionescu, Maria C;
Little, Martin;
Tilby, Michael;
Tripathy, Arvind R;
Mckenzie, Hayley S;
... Robinson, Kate; + view all
(2022)
Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study.
The Lancet Oncology
, 23
(6)
pp. 748-757.
10.1016/s1470-2045(22)00202-9.
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Lee, Yeh Chen;
King, Madeleine T;
O'Connell, Rachel L;
Lanceley, Anne;
Joly, Florence;
Hilpert, Felix;
Davis, Alison;
... GCIG Symptom Benefit Group, .; + view all
(2022)
Symptom burden and quality of life with chemotherapy for recurrent ovarian cancer: the Gynecologic Cancer InterGroup-Symptom Benefit Study.
International Journal of Gynecologic Cancer
10.1136/ijgc-2021-003142.
(In press).
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Li, Xiang;
Huang, Chun-Hao;
Sánchez-Rivera, Francisco J;
Kennedy, Margaret C;
Tschaharganeh, Darjus F;
Morris, John P;
Montinaro, Antonella;
... Lowe, Scott W; + view all
(2022)
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Proceedings of the National Academy of Sciences
, 119
(17)
, Article e2110557119. 10.1073/pnas.2110557119.
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Liebert, Casril;
Morka, Naomi;
Satish, Pranav;
Freeman, Alex;
Kelly, Daniel;
Kirkham, Alex;
Orczyk, Clement;
... Norris, Joseph M; + view all
(2022)
Diagnostic potential of radiological apical tumor involvement.
Journal of Robotic Surgery
10.1007/s11701-022-01413-w.
(In press).
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Liu, ZJ;
Deschmann, E;
Ramsey, HE;
Feldman, HA;
Psaila, B;
Cooper, N;
Vlachodimitropoulou, E;
... Sola-Visner, M; + view all
(2022)
Iron status influences the response of cord blood megakaryocyte progenitors to eltrombopag in vitro.
Blood Advances
, 6
(1)
pp. 13-27.
10.1182/bloodadvances.2021004207.
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Llimos, Gerard;
Gardeux, Vincent;
Koch, Ute;
Kribelbauer, Judith F;
Hafner, Antonina;
Alpern, Daniel;
Pezoldt, Joern;
... Deplancke, Bart; + view all
(2022)
A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation.
Nature Communications
, 13
(1)
, Article 2042. 10.1038/s41467-022-29625-6.
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Llombart, V;
Mansour, MR;
(2022)
Therapeutic targeting of "undruggable" MYC.
EBioMedicine
, 75
, Article 103756. 10.1016/j.ebiom.2021.103756.
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Lyskjær, Iben;
Kara, Neesha;
De Noon, Solange;
Davies, Christopher;
Rocha, Ana Maia;
Strobl, Anna-Christina;
Usher, Inga;
... Flanagan, Adrienne M; + view all
(2022)
Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.
European Journal of Cancer
, 168
pp. 1-11.
10.1016/j.ejca.2022.03.002.
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In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial.
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Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial.
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Journal of Neuroendocrinology
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Results of a UK real world study of polatuzumab vedotin, bendamustine, and rituximab for relapsed/refractory large B-cell lymphoma.
Blood Advances
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Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease.
Cellular and Molecular Gastroenterology and Hepatology
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Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay.
NAR Cancer
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Technologies bringing young Zebrafish from a niche field to the limelight.
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The path for medical associations to sponsor trustworthy guidelines: is it feasible?
Journal of the Royal Society of Medicine
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The translational challenges of precision oncology.
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European Journal of Cancer
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A phase 1b study evaluating the safety and preliminary efficacy of berzosertib in combination with gemcitabine in patients with advanced non-small cell lung cancer.
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Olaparib maintenance monotherapy in platinum-sensitive relapsed ovarian cancer patients without a germline BRCA1/BRCA2 mutation: OPINION primary analysis.
Gynecologic Oncology
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A UK consensus algorithm for early treatment modification in newly diagnosed systemic light-chain amyloidosis.
British Journal of Haematology
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Signatures of TOP1 transcription-associated mutagenesis in cancer and germline.
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Novel Cellular Therapies for Hepatocellular Carcinoma.
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Correction: Functional profiling of long intergenic non-coding RNAs in fission yeast.
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Parsimonious Clone Tree Integration in cancer.
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Relationship of prostate cancer topography and tumour conspicuity on multiparametric magnetic resonance imaging: a protocol for a systematic review and meta-analysis.
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International Journal of Stroke
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Characteristics of Antiphospholipid Antibody Positive Patients in AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking.
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Effects of Photobiomodulation Therapy on Regulation of Myogenic Regulatory Factor mRNA Expression In Vivo: A Systematic Review.
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Activity and toxicity of intramuscular 1000 iu/m² polyethylene glycol-E. coli L-asparaginase in the UKALL 2003 and UKALL 2011 clinical trials.
British Journal of Haematology
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A compact and simple method of achieving differential transgene expression by exploiting translational readthrough.
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Histo-MRI map study protocol: a prospective cohort study mapping MRI to histology for biomarker validation and prediction of prostate cancer.
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An overview of mutational and copy number signatures in human cancer.
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MGP Panel is a comprehensive targeted genomics panel for molecular profiling of multiple myeloma patients.
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A Novel and Automated Approach to Classify Radiation Induced Lung Tissue Damage on CT Scans.
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Prognostic value of Oncogenetic mutations in pediatric T Acute Lymphoblastic Leukemia: a comparison of UKALL2003 and FRALLE2000T protocols.
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JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation.
Cell Reports
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Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges.
British Journal of Cancer
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Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation.
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Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19.
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Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumours.
Clinical Cancer Research
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Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans.
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Image enhanced endoscopy and molecular biomarkers vs Seattle protocol to diagnose dysplasia in Barrett's esophagus.
Clinical Gastroenterology and Hepatology
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Outcome predictors for maternal red blood cell alloimmunisation with anti-K and anti-D managed with intrauterine blood transfusion.
British Journal of Haematology
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Lack of consensus identifies important areas for future clinical research: Advanced Prostate Cancer Consensus Conference (APCCC) 2019 findings.
European Journal of Cancer
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Donor whole blood DNA methylation is not a strong predictor of acute graft versus host disease in unrelated donor allogeneic haematopoietic cell transplantation.
medRxiv
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Research Progress on Postoperative Minimal/Molecular Residual Disease Detection in Lung Cancer.
Chronic Diseases and Translational Medicine
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A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Nature Cancer
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Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases.
Human Molecular Genetics
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Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma.
Nature Communications
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Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers.
Molecular Cancer Therapeutics
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Plasma Tie2 trajectories identify vascular response criteria for VEGF inhibitors across advanced biliary tract, colorectal and ovarian cancers.
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A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution.
Nature Methods
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Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS.
EMBO Molecular Medicine
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Mak, Ka-Man;
McDonald, Fiona;
Teague, Jonathan;
Faivre-Finn, Corinne;
Forster, Martin;
Hanna, Gerard;
Moinuddin, Syed;
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SARON: stereotactic ablative radiotherapy for oligometastatic non-small cell lung cancer (NSCLC).
Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual.
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Chen, Yu-Guang;
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Investigating the role of the linear ubiquitin chain assembly complex in
lymphotoxin beta receptor signalling and obesity-derived hepatitis.
Doctoral thesis (Ph.D), UCL (University College London).
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Ghorani, Ehsan;
(2022)
Intratumour CD4 T cell differentiation skewing and loss of immune fitness in non-small cell lung cancer.
Doctoral thesis (Ph.D), UCL (University College London).
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Hatipoglu, Emine;
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Deciphering the Immune Landscape in Renal Cell Carcinoma and in Anti-PD-1 Therapy.
Doctoral thesis (Ph.D), UCL (University College London).
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Holohan, Sean David;
(2022)
Dissecting the Role of Trisomy 21 in Childhood Acute Lymphoblastic Leukaemia.
Doctoral thesis (Ph.D), UCL (University College London).
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Nyoni, Lynet;
(2022)
Targeting the tumour microenvironment through death ligand inhibition.
Doctoral thesis (Ph.D), UCL (University College London).
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Zhai, Haoran;
(2022)
Investigating the role of genomic alterations and altered DNA replication timing during malignant transformation in tumours.
Doctoral thesis (Ph.D), UCL (University College London).
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Znati, Sami;
(2022)
A Translational Study of Vandetanib Treatment for Hepatocellular Carcinoma.
Doctoral thesis (Ph.D), UCL (University College London).
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