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Number of items: 318.
Article
Abdul-Kadir, Rezan;
Gomez, Keith;
(2022)
Reproductive health and hemostatic issues in women and girls with congenital factor VII deficiency: A systematic review.
Journal of Thrombosis and Haemostasis
, 20
(12)
pp. 2758-2772.
10.1111/jth.15872.
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Agbuduwe, Charles;
Iqbal, Gulnaz;
Cairns, David A;
Menzies, Tom;
Dunn, Janet;
Gregory, Walter Martin;
Kaiser, Martin F;
... Basu, Supratik; + view all
(2022)
Clinical Characteristics and Outcomes of IgD Myeloma: Experience across UK National Trials.
Blood Advances
10.1182/bloodadvances.2022007608.
(In press).
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Agerbæk, M;
Bang-Christensen, SR;
Yang, MH;
Clausen, TM;
Pereira, MA;
Sharma, S;
Ditlev, SB;
... Salanti, A; + view all
(2022)
Author Correction to: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner (Nature Communications, (2018), 9, 1, (3279), 10.1038/s41467-018-05793-2).
Nature Communications
, 13
(1)
, Article 3285. 10.1038/s41467-022-29351-z.
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Aggarwal, D;
Page, AJ;
Schaefer, U;
Savva, GM;
Myers, R;
Volz, E;
Ellaby, N;
... Harrison, EM; + view all
(2022)
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission.
Nature Communications
, 13
, Article 1012. 10.1038/s41467-022-28371-z.
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Ahrenfeldt, Johanne;
Christensen, Ditte S;
Sokac, Mateo;
Kisistok, Judit;
McGranahan, Nicholas;
Birkbak, Nicolai J;
(2022)
Computational Analysis Reveals the Temporal Acquisition of Pathway Alterations during the Evolution of Cancer.
Cancers
, 14
(23)
, Article 5817. 10.3390/cancers14235817.
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Ariëns, RA;
Hunt, BJ;
Agbani, EO;
Ahnström, J;
Ahrends, R;
Alikhan, R;
Assinger, A;
... Zhou, J; + view all
(2022)
Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress.
Research and Practice in Thrombosis and Haemostasis
, 6
(5)
, Article e12747. 10.1002/rth2.12747.
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Ascierto, Paolo A;
Agarwala, Sanjiv S;
Blank, Christian;
Caraco, Corrado;
Carvajal, Richard D;
Ernstoff, Marc S;
Ferrone, Soldano;
... Thurin, Magdalena; + view all
(2022)
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy).
Journal of Translational Medicine
, 20
, Article 391. 10.1186/s12967-022-03592-4.
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Asghar, US;
Kanani, R;
Roylance, R;
Mittnacht, S;
(2022)
Systematic Review of Molecular Biomarkers Predictive of Resistance to CDK4/6 Inhibition in Metastatic Breast Cancer.
JCO Precision Oncology
, 6
pp. 1-13.
10.1200/po.21.00002.
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Ashby, C;
Boyle, EM;
Bauer, MA;
Mikulasova, A;
Wardell, CP;
Williams, L;
Siegel, A;
... Morgan, GJ; + view all
(2022)
Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.
Blood Cancer Journal
, 12
(5)
, Article 85. 10.1038/s41408-022-00673-x.
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Asher, Samir;
Kazantzi, Aikaterini;
Dekaj, Fatjon;
Steventon, Luke;
Khatun, Aisha;
Ainley, Louise;
McMillan, Annabel;
... Popat, Rakesh; + view all
(2022)
Under-representation of ethnic minorities in early phase clinical trials for multiple myeloma.
Haematologica
, 107
(12)
pp. 2961-2965.
10.3324/haematol.2022.281322.
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Ashford, F;
Best, A;
Dunn, SJ;
Ahmed, Z;
Siddiqui, H;
Melville, J;
Wilkinson, S;
... Jamrozy, D; + view all
(2022)
SARS-CoV-2 Testing in the Community: Testing Positive Samples with the TaqMan SARS-CoV-2 Mutation Panel To Find Variants in Real Time.
Journal of Clinical Microbiology
, 60
(4)
, Article e02408-21. 10.1128/jcm.02408-21.
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Atsamnia, Djamel;
Hanini, Salah;
Oukrif, Dahmane;
Benachour, Karine;
Benkortbi, Othmane;
Hamadache, Mabrouk;
(2022)
Comparative Therapeutic Properties of Garlic Extract and Metformin on Hyperglycaemia, Hypercholesterolaemia, and Hypertriglyceridaemia in Alloxan-induced Type1-like Diabetic Rats.
Kemija u Industriji
, 71
(3-4)
pp. 141-149.
10.15255/kui.2021.035.
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Bahl, Amit;
Wilson, William;
Ball, Jessica;
Renninson, Emily;
Dubey, Sidharth;
Bravo, Alicia;
Foulstone, Emily;
... Churn, Mark; + view all
(2022)
Concept: A randomised multicentre trial of first line chemotherapy comparing three weekly cabazitaxel versus weekly paclitaxel in HER2 negative metastatic breast cancer.
The Breast
, 66
pp. 69-76.
10.1016/j.breast.2022.09.005.
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Bakhai, Ameet;
McCauley, Leah;
Stones, Liba;
Khalil, Saria;
Mehta, Jay;
Price, Nicola;
Krishnamurthy, Vinodh;
... Hughes, Derralynn; + view all
(2022)
Shining a light on an additional clinical burden: work-related digital communication survey study – COVID-19 impact on NHS staff wellbeing.
Humanities and Social Sciences Communications
, 9
, Article 414. 10.1057/s41599-022-01427-7.
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Barber, Paul R;
Mustapha, Rami;
Flores-Borja, Fabian;
Alfano, Giovanna;
Ng, Kenrick;
Weitsman, Gregory;
Dolcetti, Luigi;
... Ng, Tony; + view all
(2022)
Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development.
eLife
, 11
, Article e73288. 10.7554/eLife.73288.
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Beaton, Laura;
Tregidgo, Henry Fj;
Znati, Sami A;
Forsyth, Sharon;
Counsell, Nicholas;
Clarkson, Matthew J;
Bandula, Steven;
... Sharma, Ricky A; + view all
(2022)
Phase 0 study of vandetanib-eluting radiopaque embolics as a pre-operative embolization treatment in patients with resectable liver malignancies.
Journal of Vascular and Interventional Radiology
, 33
(9)
1034-1044.e29.
10.1016/j.jvir.2022.04.033.
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Beck, Michael;
Ramaswami, Uma;
Hernberg-Stahl, Elizabeth;
Hughes, Derralynn A;
Kampmann, Christoph;
Mehta, Atul B;
Nicholls, Kathleen;
... Giugliani, Roberto; + view all
(2022)
Twenty years of the Fabry Outcome Survey (FOS): insights, achievements, and lessons learned from a global patient registry.
Orphanet Journal of Rare Diseases
, 17
, Article 238. 10.1186/s13023-022-02392-9.
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Beird, H;
Bielack, Stefan;
Flanagan, Adrienne;
Gill, B;
Heymann, Dominique;
Janeway, Katherine;
Livingston, JA;
... Gorlick, Richard; + view all
(2022)
Osteosarcoma.
Nature Reviews Disease Primers
, 8
, Article 77. 10.1038/s41572-022-00409-y.
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Bennett, Clare;
(2022)
Loss of T cell tolerance in the skin following immunopathology is linked to failed restoration of the dermal niche by recruited macrophages.
Cell Reports
, 39
(7)
, Article 110819. 10.1016/j.celrep.2022.110819.
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Bergstrom, Erik N;
Luebeck, Jens;
Petljak, Mia;
Khandekar, Azhar;
Barnes, Mark;
Zhang, Tongwu;
Steele, Christopher D;
... Alexandrov, Ludmil B; + view all
(2022)
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA.
Nature
10.1038/s41586-022-04398-6.
(In press).
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Berndt, Sonja I;
Vijai, Joseph;
Benavente, Yolanda;
Camp, Nicola J;
Nieters, Alexandra;
Wang, Zhaoming;
Smedby, Karin E;
... Rothman, Nathaniel; + view all
(2022)
Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
Leukemia
, 36
(12)
pp. 2835-2844.
10.1038/s41375-022-01711-0.
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Best, Jonathan G;
Arram, Liz;
Ahmed, Norin;
Balogun, Maryam;
Bennett, Kate;
Bordea, Ekaterina;
Campos, Marta G;
... OPTIMAS investigators, .; + view all
(2022)
Optimal timing of anticoagulation after acute ischemic stroke with atrial fibrillation (OPTIMAS): Protocol for a randomized controlled trial.
International Journal of Stroke
, 17
(5)
pp. 583-589.
10.1177/17474930211057722.
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Bolik, J;
Krause, F;
Stevanovic, M;
Gandraß, M;
Thomsen, I;
Schacht, S-S;
Rieser, E;
... Schmidt-Arras, D; + view all
(2022)
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
J Exp Med
, 219
(1)
, Article e20201039. 10.1084/jem.20201039.
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Bonsor, Daniel A;
Alexander, Patrick;
Snead, Kelly;
Hartig, Nicole;
Drew, Matthew;
Messing, Simon;
Finci, Lorenzo I;
... Simanshu, Dhirendra K; + view all
(2022)
Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nature Structural and Molecular Biology
, 29
(10)
pp. 966-977.
10.1038/s41594-022-00841-4.
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Bortolomeazzi, Michele;
Montorsi, Lucia;
Temelkovski, Damjan;
Keddar, Mohamed Reda;
Acha-Sagredo, Amelia;
Pitcher, Michael J;
Basso, Gianluca;
... Ciccarelli, Francesca D; + view all
(2022)
A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially-resolved tissue phenotyping at single-cell resolution.
Nature Communications
, 13
, Article 781. 10.1038/s41467-022-28470-x.
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Boumelha, Jesse;
de Carné Trécesson, Sophie;
Law, Emily K;
Romero-Clavijo, Pablo;
Coelho, Matthew;
Ng, Kevin;
Mugarza, Edurne;
... Downward, Julian; + view all
(2022)
An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations.
Cancer Research
, 82
(19)
pp. 3435-3448.
10.1158/0008-5472.CAN-22-0325.
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Bowes, Amy;
Tarabichi, Maxime;
Pillay, Nischalan;
Van Loo, Peter;
(2022)
Leveraging single cell sequencing to unravel intra-tumour heterogeneity and tumour evolution in human cancers.
Journal of Pathology
, 257
(4)
pp. 466-478.
10.1002/path.5914.
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Breeze, CE;
Beck, S;
Berndt, SI;
Franceschini, N;
(2022)
The missing diversity in human epigenomic studies.
Nature Genetics
, 54
pp. 737-739.
10.1038/s41588-022-01081-4.
|
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Breeze, CE;
Haugen, E;
Reynolds, A;
Teschendorff, A;
van Dongen, J;
Lan, Q;
Rothman, N;
... Berndt, SI; + view all
(2022)
Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations.
Genome Biololgy
, 23
(1)
, Article 13. 10.1186/s13059-021-02560-3.
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Breeze, Charles E;
Wong, Jason YY;
Beck, Stephan;
Berndt, Sonja I;
Franceschini, Nora;
(2022)
Diversity in EWAS: current state, challenges, and solutions.
Genome Medicine
, 14
, Article 71. 10.1186/s13073-022-01065-3.
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Brennan, B;
Kirton, L;
Marec-Bérard, P;
Gaspar, N;
Laurence, V;
Martín-Broto, J;
Sastre, A;
... Wheatley, K; + view all
(2022)
Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.
The Lancet
, 400
(10362)
pp. 1513-1521.
10.1016/S0140-6736(22)01790-1.
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Bridgewater, John;
Fletcher, Peter;
Palmer, Daniel H;
Malik, Hassan Z;
Prasad, Raj;
Mirza, Darius;
Anthony, Alan;
... BILCAP study group, .; + view all
(2022)
Long-Term Outcomes and Exploratory Analyses of the Randomized Phase III BILCAP Study.
Journal of Clinical Oncology
, 40
(18)
pp. 2048-2057.
10.1200/JCO.21.02568.
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Bridgewater, John;
Jiao, Xiaolong;
Parimi, Mounika;
Flach, Clare;
Stratford, Jeran;
Kamburov, Atanas;
Schmitz, Arndt A;
... Bazhenova, Lyudmila; + view all
(2022)
Prognosis and oncogenomic profiling of patients with tropomyosin receptor kinase fusion cancer in the 100,000 genomes project.
Cancer Treatment and Research Communications
, 33
, Article 100623. 10.1016/j.ctarc.2022.100623.
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Brimble, MA;
Cheng, PH;
Winston, SM;
Reeves, IL;
Souquette, A;
Spence, Y;
Zhou, J;
... Davidoff, AM; + view all
(2022)
Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps.
Molecular Therapy - Methods and Clinical Development
, 24
pp. 280-291.
10.1016/j.omtm.2022.01.008.
(In press).
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Brooks, Lucy J;
Clements, Melanie P;
Burden, Jemima J;
Kocher, Daniela;
Richards, Luca;
Devesa, Sara Castro;
Zakka, Leila;
... Parrinello, Simona; + view all
(2022)
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 13
(1)
, Article 2163. 10.1038/s41467-022-29916-y.
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Brooks, Lucy J;
Simpson Ragdale, Holly;
Hill, Ciaran Scott;
Clements, Melanie;
Parrinello, Simona;
(2022)
Injury programs shape glioblastoma.
Trends in Neurosciences
10.1016/j.tins.2022.08.006.
(In press).
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Brown, Sarah R;
Hinsley, Samantha;
Hall, Emma;
Hurt, Chris;
Baird, Richard D;
Forster, Martin;
Scarsbrook, Andrew F;
(2022)
A Road Map for Designing Phase I Clinical Trials of Radiotherapy–Novel Agent Combinations.
Clinical Cancer Research
, 28
(17)
pp. 3639-3651.
10.1158/1078-0432.CCR-21-4087.
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Budde, Axel;
Baust, Katja;
Weinhold, Leonie;
Bernstein, Mark;
Bielack, Stefan;
Dhooge, Catharina;
Hjorth, Lars;
... Schmid, Matthias; + view all
(2022)
Erratum to 'Linking EORTC QLQ-C-30 and PedsQL/PEDQOL physical functioning scores in patients with osteosarcoma' [Eur J Cancer 170 (2022) 209-235].
European Journal of Cancer
, 177
pp. 208-209.
10.1016/j.ejca.2022.06.053.
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Bustoros, Mark;
Anand, Shankara;
Sklavenitis-Pistofidis, Romanos;
Redd, Robert;
Boyle, Eileen M;
Zhitomirsky, Benny;
Dunford, Andrew J;
... Ghobrial, Irene M; + view all
(2022)
Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes.
Nature Communications
, 13
, Article 3449. 10.1038/s41467-022-30694-w.
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Cabeza-Segura, M;
Gambardella, V;
Gimeno-Valiente, F;
Carbonell-Asins, JA;
Alarcón-Molero, L;
González-Vilanova, A;
Zuñiga-Trejos, S;
... Fleitas, T; + view all
(2022)
Integrative immune transcriptomic classification improves patient selection for precision immunotherapy in advanced gastro-oesophageal adenocarcinoma.
British Journal of Cancer
, 127
(12)
pp. 2198-2206.
10.1038/s41416-022-02005-z.
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Camilleri, Marquita;
Bekris, Georgios;
Sidhu, Govundeep;
Buck, Caroline;
Elsden, Esma;
McCourt, Orla;
Horder, Jackie;
... Fisher, Abigail; + view all
(2022)
The impact of COVID-19 on autologous stem cell transplantation in multiple myeloma: A single-centre, qualitative evaluation study.
Supportive Care in Cancer
10.1007/s00520-022-07173-5.
(In press).
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Campbell, Rachel;
Costa, Daniel SJ;
Stockler, Martin R;
Lee, Yeh Chen;
Ledermann, Jonathan A;
Berton, Dominique;
Sehouli, Jalid;
... GCIG Symptom Benefit Group; + view all
(2022)
Measure of Ovarian Symptoms and Treatment concerns (MOST) indexes and their associations with health-related quality of life in recurrent ovarian cancer.
Gynecologic Oncology
, 166
(2)
pp. 254-262.
10.1016/j.ygyno.2022.05.024.
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Cardenas, Andres;
Ecker, Simone;
Fadadu, Raj P;
Huen, Karen;
Orozco, Allan;
McEwen, Lisa M;
Engelbrecht, Hannah-Ruth;
... Rehkopf, David H; + view all
(2022)
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults.
Scientific Reports
, 12
, Article 4277. 10.1038/s41598-022-08160-w.
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Casali, PG;
Blay, JY;
Abecassis, N;
Bajpai, J;
Bauer, S;
Biagini, R;
Bielack, S;
... Stacchiotti, S; + view all
(2022)
Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Annals of Oncology
, 33
(1)
pp. 20-33.
10.1016/j.annonc.2021.09.005.
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Chakravarthy, Ankur;
Reddin, Ian;
Henderson, Stephen;
Dong, Cindy;
Kirkwood, Nerissa;
Jeyakumar, Maxmilan;
Rodriguez, Daniela Rothschild;
... Fenton, Tim R; + view all
(2022)
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Nature Communications
, 13
, Article 5818. 10.1038/s41467-022-33544-x.
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Chan, WY;
Counsell, N;
de Tute, R;
De-Silva, D;
Phillips, EH;
Cavenagh, J;
Adedayo, T;
... Yong, KL; + view all
(2022)
Outcomes of relapse in patients with deferred autologous stem cell transplant after achieving at least very good partial response following bortezomib, adriamycin, dexamethasone chemotherapy for newly diagnosed multiple myeloma in the phase II PADIMAC trial.
British Journal of Haematology
, 196
(4)
e33-e37.
10.1111/bjh.17903.
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Chan, WY;
Zhu, C;
Sanchez, E;
Gupta, R;
Fielding, AK;
Khwaja, A;
Payne, EM;
(2022)
Antibody responses to SARS-CoV-2 vaccination in patients with acute myeloid leukaemia and high risk MDS on active anti-cancer therapies.
British Journal of Haematology
, 198
(3)
pp. 478-481.
10.1111/bjh.18248.
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Chen, Kezhong;
Yang, Airong;
Carbone, David P;
Kanu, Nnennaya;
Liu, Ke;
Wang, Ruiru;
Nie, Yuntao;
... Wang, Jun; + view all
(2022)
Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers.
Cell Reports
, 40
(2)
, Article 111047. 10.1016/j.celrep.2022.111047.
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Cheok, Kathleen PL;
Kirkwood, Amy A;
Menne, Tobias;
Tholouli, Eleni;
Chaganti, Sridhar;
Mathew, Amrith;
Uttenthal, Ben;
... Roddie, Claire; + view all
(2022)
Severe presentations and high mortality from SARS-CoV-2 in patients undergoing chimeric antigen receptor (CAR-T) therapy: a UK NCCP analysis.
Leukemia & Lymphoma
, 63
(8)
pp. 1980-1984.
10.1080/10428194.2022.2057487.
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Chervova, Olga;
Chernysheva, Elizabeth;
Panteleeva, Kseniia;
Widayati, Tyas Arum;
Hrbkova, Natalie;
Schneider, Jadesada;
Maximov, Vladimir;
... Beck, Stephan; + view all
(2022)
Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort.
Biology
, 12
(1)
, Article 68. 10.3390/biology12010068.
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Chowdary, P;
Nathwani, A;
(2022)
Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B: The authors reply.
New England Journal of Medicine
, 387
(14)
pp. 1336-1337.
10.1056/NEJMc2210918.
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Chowdary, P;
Shapiro, S;
Makris, M;
Evans, G;
Boyce, S;
Talks, K;
Dolan, G;
... Nathwani, A; + view all
(2022)
Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B.
The New England Journal of Medicine
, 387
(3)
pp. 237-247.
10.1056/NEJMoa2119913.
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Christensen, Ditte S;
Ahrenfeldt, Johanne;
Sokac, Mateo;
Kisistok, Judit;
Thomsen, Martin K;
Maretty, Lasse;
McGranahan, Nicholas;
(2022)
Treatment Represents a Key Driver of Metastatic Cancer Evolution.
Cancer Research
, 82
(16)
pp. 2918-2927.
10.1158/0008-5472.CAN-22-0562.
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Cooke, EA;
Smith, NAS;
Thomas, SA;
Ruston, C;
Hothi, S;
Hughes, D;
(2022)
An integrated discrete event simulation and particle swarm optimisation model for optimising efficiency of cancer diagnosis pathways.
Healthcare Analytics
, 2
, Article 100082. 10.1016/j.health.2022.100082.
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Cortellini, Alessio;
Aguilar-Company, Juan;
Salazar, Ramon;
Bower, Mark;
Sita-Lumsden, Ailsa;
Plaja, Andrea;
Lee, Alvin JX;
... Pinato, David J; + view all
(2022)
Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer.
British Journal of Cancer
10.1038/s41416-022-01952-x.
(In press).
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Cortellini, Alessio;
Gennari, Alessandra;
Pommeret, Fanny;
Patel, Grisma;
Newsom-Davis, Thomas;
Bertuzzi, Alexia;
Viladot, Margarita;
... OnCovid study group, .; + view all
(2022)
COVID-19 Sequelae and the Host Pro-Inflammatory Response: An Analysis From the OnCovid Registry.
JNCI: Journal of the National Cancer Institute
, 114
(7)
pp. 979-987.
10.1093/jnci/djac057.
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Cortellini, Alessio;
Salazar, Ramon;
Gennari, Alessandra;
Aguilar-Company, Juan;
Bower, Mark;
Bertuzzi, Alexia;
Brunet, Joan;
... Pinato, David J; + view all
(2022)
Persistence of long-term COVID-19 sequelae in patients with cancer: an analysis from the OnCovid registry.
European Journal of Cancer
, 170
pp. 10-16.
10.1016/j.ejca.2022.03.019.
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Cottone, Lucia;
Ligammari, Lorena;
Lee, Hang-Mao;
Knowles, Helen J;
Henderson, Stephen;
Bianco, Sara;
Davies, Christopher;
... Flanagan, Adrienne M; + view all
(2022)
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cell Death & Differentiation
, 29
pp. 2459-2471.
10.1038/s41418-022-01031-x.
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Cross, William;
Lyskjær, Iben;
Lesluyes, Tom;
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A Phase II Trial of a Personalized, Dose-Intense Administration Schedule of 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-Risk Neuroblastoma–LuDO-N.
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A Novel and Automated Approach to Classify Radiation Induced Lung Tissue Damage on CT Scans.
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Role of 3'-Deoxy-3'-[¹⁸F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase.
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Nature Biotechnology
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JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation.
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British Gynaecological Cancer Society Recommendations for Women With Gynecological Cancer Who Received Non-standard Care During the COVID-19 Pandemic.
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Community voices: policy proposals to promote inclusion in academia through the lens of women in science.
Nature Communications
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Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination.
EMBO Molecular Medicine
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Genome Medicine
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Constantinou, Georgia;
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Long-term treatment of cancer-prone germline PTEN mutant mice with low-dose rapamycin extends lifespan and delays tumour development.
The Journal of Pathology
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Detection of COPD in the SUMMIT Study Lung Cancer Screening Cohort using Symptoms and Spirometry.
European Respiratory Journal
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Wu, Anjui;
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Blood-based liquid biopsies for prostate cancer: clinical opportunities and challenges.
British Journal of Cancer
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Haefliger, Simon;
Ameline, Baptiste;
Alborelli, Ilaria;
Calgua, Byron;
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Brown Tumors Belong to the Spectrum of KRAS-driven Neoplasms.
The American Journal of Surgical Pathology
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Biphenotypic sinonasal sarcoma: European multicentre case-series and systematic literature review.
Acta Otorhinolaryngologica Italica
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Bond, Gareth L;
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Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants.
Frontiers in Genome Editing
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Precision Targeting of Mutant PI3Kα in Cancer by Selective Degradation.
Cancer Discovery
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Arnold, Roland;
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Cheng, Vinton WT;
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Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19.
JAMA Network Open
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Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.
The Lancet Oncology
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Akarca, Ayse U;
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Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumours.
Clinical Cancer Research
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Deng, J;
Treacy, C;
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Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans.
Cell Death & Disease
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Ortiz-Fernandez-Sordo, Jacobo;
Oukrif, Dahmane;
Pappas, Apostolos;
Januszewicz, Wladyslaw;
O'Donovan, Maria;
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(2022)
Image enhanced endoscopy and molecular biomarkers vs Seattle protocol to diagnose dysplasia in Barrett's esophagus.
Clinical Gastroenterology and Hepatology
10.1016/j.cgh.2022.01.060.
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Vlachodimitropoulou, E;
Garbowski, M;
Anne Solomon, S;
Abbasi, N;
Seaward, G;
Windrim, R;
Keunen, J;
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(2022)
Outcome predictors for maternal red blood cell alloimmunisation with anti-K and anti-D managed with intrauterine blood transfusion.
British Journal of Haematology
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10.1111/bjh.17956.
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Beer, TM;
Davis, ID;
Shore, ND;
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Ost, P;
Attard, G;
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(2022)
Lack of consensus identifies important areas for future clinical research: Advanced Prostate Cancer Consensus Conference (APCCC) 2019 findings.
European Journal of Cancer
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10.1016/j.ejca.2021.09.036.
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Wald, Nicholas J;
Duffy, Stephen W;
Hackshaw, Allan;
(2022)
When alternatives to screening should be the priority.
Journal of Medical Screening
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Walker, K;
Hinsley, S;
Phillip, R;
Oughton, JB;
Murden, G;
Chalmers, AJ;
Faivre-Finn, C;
... Young, R; + view all
(2022)
Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations-CONCORDE.
JCO Precision Oncology
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Webster, Amy P;
Ecker, Simone;
Moghul, Ismail;
Dhami, Pawan;
Marzi, Sarah;
Paul, Dirk S;
Kuxhausen, Michelle;
... Beck, Stephan; + view all
(2022)
Donor whole blood DNA methylation is not a strong predictor of acute graft versus host disease in unrelated donor allogeneic haematopoietic cell transplantation.
medRxiv
10.1101/2022.03.08.22272071.
(In press).
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Willett, BJ;
Grove, J;
MacLean, OA;
Wilkie, C;
De Lorenzo, G;
Furnon, W;
Cantoni, D;
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(2022)
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Nature Microbiology
10.1038/s41564-022-01143-7.
(In press).
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Wilson, MR;
Eyre, TA;
Kirkwood, AA;
Wong Doo, N;
Soussain, C;
Choquet, S;
Martinez-Calle, N;
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(2022)
Timing of high-dose methotrexate CNS prophylaxis in DLBCL: a multicenter international analysis of 1384 patients.
Blood
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10.1182/blood.2021014506.
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Windsor, Rachael;
Hamilton, Anthony;
McTiernan, Anne;
Dileo, Palma;
Michelagnoli, Maria;
Seddon, Beatrice;
Strauss, Sandra J;
(2022)
Survival after high-dose chemotherapy for refractory and recurrent Ewing sarcoma.
European Journal of Cancer
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10.1016/j.ejca.2022.04.007.
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Wood, GE;
Ledermann, JA;
(2022)
Adjuvant and post-surgical treatment in high-grade epithelial ovarian cancer.
Best Practice & Research Clinical Obstetrics & Gynaecology
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pp. 64-73.
10.1016/j.bpobgyn.2021.09.002.
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Wray, Jason P;
Deltcheva, Elitza M;
Boiers, Charlotta;
Richardson, Simon Е;
Chhetri, Jyoti Bikram;
Brown, John;
Gagrica, Sladjana;
... Enver, Tariq; + view all
(2022)
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability.
Nature Communications
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Wright, DW;
Harvey, WT;
Hughes, J;
Cox, M;
Peacock, TP;
Colquhoun, R;
Jackson, B;
... Hassan-Ibrahim, MO; + view all
(2022)
Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer.
Virus Evolution
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Wu, Honghan;
Wang, Minhong;
Wu, Jinge;
Francis, Farah;
Chang, Yun-Hsuan;
Shavick, Alex;
Dong, Hang;
... Dobson, Richard JB; + view all
(2022)
A survey on clinical natural language processing in the United Kingdom from 2007 to 2022.
npj Digital Medicine
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, Article 186. 10.1038/s41746-022-00730-6.
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Wu, M;
Shen, H;
Wang, Z;
Kanu, N;
Chen, K;
(2022)
Research Progress on Postoperative Minimal/Molecular Residual Disease Detection in Lung Cancer.
Chronic Diseases and Translational Medicine
10.1002/cdt3.10.
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Wu, Mary Y;
Carr, Edward J;
Harvey, Ruth;
Mears, Harriet V;
Kjaer, Svend;
Townsley, Hermaleigh;
Hobbs, Agnieszka;
... Bauer, David LV; + view all
(2022)
WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed.
The Lancet
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pp. 2193-2196.
10.1016/s0140-6736(22)01938-9.
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Wu, Wenyi;
Ma, Gaoen;
Qi, Hui;
Dong, Lijun;
Chen, Fang;
Wang, Yun;
Mao, Xingxing;
... Lei, Hetian; + view all
(2022)
Genome Editing of Pik3cd Impedes Abnormal Retinal Angiogenesis.
Human Gene Therapy
10.1089/hum.2022.079.
(In press).
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Wu, Yin;
Biswas, Dhruva;
Usaite, Ieva;
Angelova, Mihaela;
Boeing, Stefan;
Karasaki, Takahiro;
Veeriah, Selvaraju;
... Swanton, Charles; + view all
(2022)
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Nature Cancer
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10.1038/s43018-022-00376-z.
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Xu, Ke;
Childerhouse, Anna;
Gupta, Rajeev;
(2022)
Burkitt leukaemia with B-cell precursor immunophenotype.
eJHaem
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pp. 1044-1045.
10.1002/jha2.450.
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Yngvadottir, Bryndis;
Andreou, Avgi;
Bassaganyas, Laia;
Larionov, Alexey;
Cornish, Alex J;
Chubb, Daniel;
Saunders, Charlie N;
... Maher, Eamonn R; + view all
(2022)
Frequency of pathogenic germline variants in cancer susceptibility genes in 1336 renal cell carcinoma cases.
Human Molecular Genetics
, Article ddac089. 10.1093/hmg/ddac089.
(In press).
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Yong, K;
Wilson, W;
de Tute, RM;
Camilleri, M;
Ramasamy, K;
Streetly, M;
Sive, J;
... Popat, R; + view all
(2022)
Upfront autologous haematopoietic stem-cell transplantation versus carfilzomib–cyclophosphamide–dexamethasone consolidation with carfilzomib maintenance in patients with newly diagnosed multiple myeloma in England and Wales (CARDAMON): a randomised, phase 2, non-inferiority trial.
The Lancet Haematology
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e93-e106.
10.1016/S2352-3026(22)00350-7.
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Yousefi, Maryam;
Boross, Gábor;
Weiss, Carly;
Murray, Christopher W;
Hebert, Jess D;
Cai, Hongchen;
Ashkin, Emily L;
... Winslow, Monte M; + view all
(2022)
Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities.
Cancer Research
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pp. 1589-1602.
10.1158/0008-5472.CAN-22-0059.
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Zachara, Magda;
Rainer, Pernille Y;
Hashimi, Horia;
Russeil, Julie M;
Alpern, Daniel;
Ferrero, Radiana;
Litovchenko, Maria;
(2022)
Mammalian adipogenesis regulator (Areg) cells use retinoic acid signalling to be non- and anti-adipogenic in age-dependent manner.
The EMBO Journal
, Article e108206. 10.15252/embj.2021108206.
(In press).
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Zakeri, N;
Hall, A;
Swadling, L;
Pallett, LJ;
Schmidt, NM;
Diniz, MO;
Kucykowicz, S;
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(2022)
Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma.
Nature Communications
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Zammarchi, Francesca;
Havenith, Karin Eg;
Chivers, Simon;
Hogg, Paul;
Bertelli, Francois;
Tyrer, Peter;
Janghra, Narinder;
... van Berkel, Patrick H; + view all
(2022)
Preclinical Development of ADCT-601, a Novel Pyrrolobenzodiazepine Dimer-based Antibody-drug Conjugate Targeting AXL-expressing Cancers.
Molecular Cancer Therapeutics
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pp. 582-593.
10.1158/1535-7163.MCT-21-0715.
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Zhang, Xiaoyan;
Yang, Ling;
Lei, Wanjun;
Hou, Qiang;
Huang, Ming;
Zhou, Rongjing;
Enver, Tariq;
(2022)
Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer.
EBioMedicine
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Zhao, Yi;
Simpson, Benjamin S;
Morka, Naomi;
Freeman, Alex;
Kirkham, Alex;
Kelly, Daniel;
Whitaker, Hayley C;
... Norris, Joseph M; + view all
(2022)
Comparison of Multiparametric Magnetic Resonance Imaging with Prostate-Specific Membrane Antigen Positron-Emission Tomography Imaging in Primary Prostate Cancer Diagnosis: A Systematic Review and Meta-Analysis.
Cancers
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Zhou, C;
O'Connor, J;
Backen, A;
Valle, JW;
Bridgewater, J;
Dive, C;
Jayson, GC;
(2022)
Plasma Tie2 trajectories identify vascular response criteria for VEGF inhibitors across advanced biliary tract, colorectal and ovarian cancers.
ESMO Open
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Zhu, Tianyu;
Liu, Jacklyn;
Beck, Stephan;
Pan, Sun;
Capper, David;
Lechner, Matt;
Thirlwell, Chrissie;
... Teschendorff, Andrew E; + view all
(2022)
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution.
Nature Methods
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pp. 296-306.
10.1038/s41592-022-01412-7.
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Zinngrebe, Julia;
Moepps, Barbara;
Monecke, Thomas;
Gierschik, Peter;
Schlichtig, Ferdinand;
Barth, Thomas FE;
Strauß, Gudrun;
... Debatin, Klaus-Michael; + view all
(2022)
Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS.
EMBO Molecular Medicine
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, Article e14901. 10.15252/emmm.202114901.
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Proceedings paper
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Barmpoutis, P;
Waddingham, W;
Ross, C;
Hamzeh, K;
Alexander, DC;
Jansen, M;
(2022)
Gland segmentation in gastric histology images: detection of intestinal metaplasia.
In:
2022 30th European Signal Processing Conference (EUSIPCO).
(pp. pp. 1338-1342).
IEEE: Belgrade, Serbia.
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Barmpoutis, Panagiotis;
Yuan, Jing;
Waddingham, William;
Ross, Christopher;
Hamzeh, Kayhanian;
Stathaki, Tania;
Alexander, Daniel C;
(2022)
Multi-scale Deformable Transformer for the Classification of Gastric Glands: The IMGL Dataset.
In: Ali, S and VanDerSommen, F and Papiez, BW and VanEijnatten, M and Jin, Y and Kolenbrander, I, (eds.)
MICCAI Workshop on Cancer Prevention through Early Detection CaPTion 2022: Cancer Prevention Through Early Detection.
(pp. pp. 24-33).
Springer, Cham
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Zhang, H;
AbdulJabbar, K;
Grunewald, T;
Akarca, A;
Hagos, Y;
Lecat, C;
Pate, D;
... Yuan, Y; + view all
(2022)
Self-supervised Antigen Detection Artificial Intelligence (SANDI).
In: Xu, X and Li, X and Mahapatra, D and Cheng, L and Petitjean, C and Fu, H, (eds.)
Resource-Efficient Medical Image Analysis: First MICCAI Workshop, REMIA 2022, Singapore, September 22, 2022, Proceedings.
(pp. pp. 12-21).
Springer: Cham, Switzerland.
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Report
|
HSIB;
(2022)
Clinical decision making: diagnosis and treatment of pulmonary embolism in emergency departments.
Healthcare Safety Investigation Branch
|
|
Royal College of Physicians;
Royal College of Pathologists;
British Society for Genetic Medicine;
(2022)
Genetic testing in childhood: Guidance for clinical practice.
Royal College of Physicians, Royal College of Pathologists and British Society for Genetic Medicine: London, UK.
|
Working / discussion paper
|
Amodeo, Valeria;
Davies, Timothy;
Martinez-Segura, Amalia;
Clements, Melanie;
Ragdale, Holly Simpson;
Bailey, Andrew;
Silva Dos Santos, Mariana;
... Parrinello, Simona; + view all
(2022)
Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells.
bioRxiv: Cold Spring Harbor, NY, USA.
|
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Conference item
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Mak, Ka-Man;
McDonald, Fiona;
Teague, Jonathan;
Faivre-Finn, Corinne;
Forster, Martin;
Hanna, Gerard;
Moinuddin, Syed;
... Saron, TMG; + view all
(2022)
SARON: stereotactic ablative radiotherapy for oligometastatic non-small cell lung cancer (NSCLC).
Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual.
|
Poster
|
Rane, Jayant;
Harsanyi, Csilla;
Grimes, Helen;
Moinuddin, Syed;
Quingua, Kristina;
Petkar, Shabnam;
Dubash, Suraiya;
... Wilson, James; + view all
(2022)
Tumour location is important in selecting patients who may benefit from abdominal compression when receiving SABR for lung tumours.
Presented at: 20th Annual British Thoracic Oncology Group Conference 2022, Virtual conference.
|
|
Thesis
|
Chandy, Edward T. J.;
(2022)
Quantitative Analysis of Radiation-Associated Parenchymal Lung Change.
Doctoral thesis (M.D(Res)), UCL (University College London).
|
|
|
Charalambous, Xenia;
(2022)
Tumour-Priming of Human Natural Killer Cells and the Impact of Tumour Microenvironment in Ovarian Cancer.
Doctoral thesis (Ph.D), UCL (University College London.
|
|
Chen, Yu-Guang;
(2022)
Investigating the role of the linear ubiquitin chain assembly complex in
lymphotoxin beta receptor signalling and obesity-derived hepatitis.
Doctoral thesis (Ph.D), UCL (University College London).
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Fiaccadori, Valeria;
(2022)
Development of a CD30-directed CAR-T cell for the treatment of relapsed/refractory classical Hodgkin Lymphoma.
Doctoral thesis (Ph.D), UCL (University College London).
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Ganguli, Sushila;
(2022)
The Effects of Oncogenic Ras on Epithelial Cell Division.
Doctoral thesis (Ph.D), UCL (University College London).
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Garcia Diaz, Claudia;
(2022)
Novel de novo Glioblastoma mouse models reveal differences in the biology of the tumour bulk and invasive margin.
Doctoral thesis (Ph.D), UCL (University College London).
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Ghorani, Ehsan;
(2022)
Intratumour CD4 T cell differentiation skewing and loss of immune fitness in non-small cell lung cancer.
Doctoral thesis (Ph.D), UCL (University College London).
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Grist, Emily;
(2022)
Biomarker Development for Advanced Prostate Cancer.
Doctoral thesis (Ph.D), UCL (University College London).
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Hatipoglu, Emine;
(2022)
Deciphering the Immune Landscape in Renal Cell Carcinoma and in Anti-PD-1 Therapy.
Doctoral thesis (Ph.D), UCL (University College London).
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Holohan, Sean David;
(2022)
Dissecting the Role of Trisomy 21 in Childhood Acute Lymphoblastic Leukaemia.
Doctoral thesis (Ph.D), UCL (University College London).
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Jha, Ram;
(2022)
Development of a protein-protein displacement platform using an anti-minocycline single domain antibody and a dedicated displaceable peptide for the generation of an OFF-switch CAR T cell.
Doctoral thesis (Ph.D), UCL (University College London).
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Maciocia, Nicola Christina;
(2022)
Anti-CD21 Chimeric Antigen Receptor Therapy for the Treatment of T-cell Acute Lymphoblastic Leukaemia.
Doctoral thesis (Ph.D), UCL (University College London).
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Main, Kavit Harpal Singh;
(2022)
Targeting Twist: Single Molecule Insights into the
Effect of DNA Supercoiling on Topoisomerase
Interactions and Topoisomerase Inhibitor
Chemotherapeutics.
Doctoral thesis (Ph.D), UCL (University College London).
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McCourt, Orla;
(2022)
Exercise during stem cell transplantation for haematological cancer - exploring the feasibility of embedding exercise within a clinical pathway in multiple myeloma.
Doctoral thesis (Ph.D), UCL (University College London).
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Ng, Kien Hoe;
(2022)
Mapping the MHC-I Immunopeptidome in Solid Tumours: The Impact of Cellular Stress on Antigen Presentation.
Doctoral thesis (Ph.D), UCL (University College London).
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Nyoni, Lynet;
(2022)
Targeting the tumour microenvironment through death ligand inhibition.
Doctoral thesis (Ph.D), UCL (University College London).
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Simpson, Benjamin Scott;
(2022)
Evaluating novel prognostic biomarkers in prostate cancer.
Doctoral thesis (Ph.D), UCL (University College London).
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Tanner, Lewis E. S.;
(2022)
Characterising the effect of novel SFK phosphorylation on ADP Ribosylation Factor (ARF) state changes.
Doctoral thesis (Ph.D), UCL (University College London).
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Weeks, Samuel Luke;
(2022)
Characterisation of the roles of Stag paralogs in transitions of pluripotency.
Doctoral thesis (Ph.D), UCL (University College London).
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Zhai, Haoran;
(2022)
Investigating the role of genomic alterations and altered DNA replication timing during malignant transformation in tumours.
Doctoral thesis (Ph.D), UCL (University College London).
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Znati, Sami;
(2022)
A Translational Study of Vandetanib Treatment for Hepatocellular Carcinoma.
Doctoral thesis (Ph.D), UCL (University College London).
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