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Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline

Howard, Sasha R; Freeston, Sarah; Harrison, Barney; Izatt, Louise; Natu, Sonali; Newbold, Kate; Pomplun, Sabine; ... Gaze, Mark N; + view all (2022) Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline. Endocrine-Related Cancer , 29 (11) G1-G33. 10.1530/ERC-22-0035. Green open access

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Abstract

This guideline is written as a reference document for clinicians presented with the challenge of managing paediatric patients with differentiated thyroid carcinoma up to the age of 19 years. Care of paediatric patients with differentiated thyroid carcinoma differs in key aspects from that of adults, and there have been several re cent developments in the care pathways for this condition; this guideline has sought to identify and attend to these areas. It addresses the presentation, clinical assessment, diagnosis, management (both surgical and medical), genetic counselling, follow-up and prognosis of affected patients. The guideline development group formed of a multi-disciplinary panel of sub-speciality experts carried out a systematic primary literature review and Delphi Consensus exercise. The guideline was developed in accordance with The Appraisal of Guidelines Research and Evaluation Instrument II criteria, with input from stakeholders including charities and patient groups. Based on scientific evidence and expert opinion, 58 recommendations have been collected to produce a clear, pragmatic set of manage ment guidelines. It is intended as an evidence base for future optimal management and to improve the quality of clinical care of paediatric patients with differentiated thyroid carcinoma.

Type: Article
Title: Paediatric differentiated thyroid carcinoma: a UK National Clinical Practice Consensus Guideline
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1530/ERC-22-0035
Publisher version: https://doi.org/10.1530/ERC-22-0035
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License.
Keywords: thyroid; papillary thyroid cancer; follicular thyroid cancer; paediatric cancer; differentiated thyroid cancer
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: https://discovery.ucl.ac.uk/id/eprint/10182208
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