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Number of items: 444.

Article

Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; ... Dessimoz, C; + view all Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; Moore, DA; Veeriah, S; Rosenthal, R; Marafioti, T; Kirkizlar, E; Watkins, TBK; McGranahan, N; Ward, S; Martinson, L; Riley, J; Fraioli, F; Al Bakir, M; Gronroos, E; Zambrana, F; Endozo, R; Bi, WL; Fennessy, FM; Sponer, N; Johnson, D; Laycock, J; Shafi, S; Czyzewska-Khan, J; Rowan, A; Chambers, T; Matthews, N; Turajlic, S; Hiley, C; Lee, SM; Forster, MD; Ahmad, T; Falzon, M; Borg, E; Lawrence, D; Hayward, M; Kolvekar, S; Panagiotopoulos, N; Janes, SM; Thakrar, R; Ahmed, A; Blackhall, F; Summers, Y; Hafez, D; Naik, A; Ganguly, A; Kareht, S; Shah, R; Joseph, L; Quinn, AM; Crosbie, PA; Naidu, B; Middleton, G; Langman, G; Trotter, S; Nicolson, M; Remmen, H; Kerr, K; Chetty, M; Gomersall, L; Fennell, DA; Nakas, A; Rathinam, S; Anand, G; Khan, S; Russell, P; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Lester, JF; Kornaszewska, M; Attanoos, R; Adams, H; Davies, H; Oukrif, D; Akarca, AU; Hartley, JA; Lowe, HL; Lock, S; Iles, N; Bell, H; Ngai, Y; Elgar, G; Szallasi, Z; Schwarz, RF; Herrero, J; Stewart, A; Quezada, SA; Peggs, KS; Van Loo, P; Dive, C; Lin, CJ; Rabinowitz, M; Aerts, HJWL; Hackshaw, A; Shaw, JA; Zimmermann, BG; Swanton, C; Jamal-Hanjani, M; Abbosh, C; Veeriah, S; Shafi, S; Czyzewska-Khan, J; Johnson, D; Laycock, J; Bosshard-Carter, L; Goh, G; Rosenthal, R; Gorman, P; Murugaesu, N; Hynds, RE; Wilson, GA; Birkbak, NJ; Watkins, TBK; McGranahan, N; Horswell, S; Al Bakir, M; Gronroos, E; Mitter, R; Escudero, M; Stewart, A; Van Loo, P; Rowan, A; Xu, H; Turajlic, S; Hiley, C; Goldman, J; Stone, RK; Denner, T; Matthews, N; Elgar, G; Ward, S; Biggs, J; Costa, M; Begum, S; Phillimore, B; Chambers, T; Nye, E; Graca, S; Joshi, K; Furness, A; Ben Aissa, A; Wong, YNS; Georgiou, A; Quezada, SA; Peggs, KS; Hartley, JA; Lowe, HL; Herrero, J; Lawrence, D; Hayward, M; Panagiotopoulos, N; Kolvekar, S; Falzon, M; Borg, E; Marafioti, T; Simeon, C; Hector, G; Smith, A; Aranda, M; Novelli, M; Oukrif, D; Akarca, AU; Janes, SM; Thakrar, R; Forster, MD; Ahmad, T; Lee, SM; Papadatos-Pastos, D; Carnell, D; Mendes, R; George, J; Navani, N; Ahmed, A; Taylor, M; Choudhary, J; Summers, Y; Califano, R; Taylor, P; Shah, R; Krysiak, P; Rammohan, K; Fontaine, E; Booton, R; Evison, M; Crosbie, PA; Moss, S; Idries, F; Joseph, L; Bishop, P; Chaturvedi, A; Quinn, AM; Doran, H; Leek, A; Harrison, P; Moore, K; Waddington, R; Novasio, J; Blackhall, F; Rogan, J; Smith, E; Dive, C; Tugwood, J; Brady, G; Rothwell, DG; Chemi, F; Pierce, J; Gulati, S; Naidu, B; Langman, G; Trotter, S; Bellamy, M; Bancroft, H; Kerr, A; Kadiri, S; Webb, J; Middleton, G; Djearaman, M; Fennell, DA; Shaw, JA; Le Quesne, J; Moore, DA; Thomas, A; Walter, H; Riley, J; Martinson, L; Nakas, A; Rathinam, S; Monteiro, W; Marshall, H; Nelson, L; Bennett, J; Primrose, L; Anand, G; Khan, S; Amadi, A; Nicolson, M; Kerr, K; Palmer, S; Remmen, H; Miller, J; Buchan, K; Chetty, M; Gomersall, L; Lester, JF; Edwards, A; Morgan, F; Adams, H; Davies, H; Kornaszewska, M; Attanoos, R; Lock, S; Verjee, A; MacKenzie, M; Wilcox, M; Bell, H; Iles, N; Hackshaw, A; Ngai, Y; Smith, S; Gower, N; Ottensmeier, C; Chee, S; Johnson, B; Alzetani, A; Shaw, E; Lim, E; De Sousa, P; Barbosa, MT; Bowman, A; Jordan, S; Rice, A; Raubenheimer, H; Proli, C; Cufari, ME; Ronquillo, JC; Kwayie, A; Bhayani, H; Hamilton, M; Bakar, Y; Mensah, N; Ambrose, L; Devaraj, A; Buderi, S; Finch, J; Azcarate, L; Chavan, H; Green, S; Mashinga, H; Nicholson, AG; Lau, K; Sheaff, M; Schmid, P; Conibear, J; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Russell, P; Light, T; Horey, T; Danson, S; Bury, J; Edwards, J; Hill, J; Matthews, S; Kitsanta, Y; Suvarna, K; Fisher, P; Keerio, AD; Shackcloth, M; Gosney, J; Postmus, P; Feeney, S; Asante-Siaw, J; Constantin, T; Salari, R; Sponer, N; Naik, A; Zimmermann, BG; Rabinowitz, M; Aerts, HJWL; Dentro, S; Dessimoz, C; - view fewer (2017) Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution. Nature , 545 pp. 446-451. 10.1038/nature22364.

Abbosh, C; Venkatesan, S; Janes, SM; Fitzgerald, RC; Swanton, C; (2017) Evolutionary dynamics in pre-invasive neoplasia. Current Opinion in System Biology , 2 pp. 1-8. 10.1016/j.coisb.2017.02.009.

Abdallah, S; Benetos, E; Gold, NE; Hargreaves, S; Weyde, T; Wolff, D; (2017) The Digital Music Lab: A Big Data Infrastructure for Digital Musicology. ACM Journal on Computing and Cultural Heritage , 10 (1) , Article 2. 10.1145/2983918.

Abraham, BJ; Hnisz, D; Weintraub, AS; Kwiatkowski, N; Li, CH; Li, Z; Weichert-Leahey, N; ... Young, RA; + view all Abraham, BJ; Hnisz, D; Weintraub, AS; Kwiatkowski, N; Li, CH; Li, Z; Weichert-Leahey, N; Rahman, S; Liu, Y; Etchin, J; Li, B; Shen, S; Lee, TI; Zhang, J; Look, AT; Mansour, MR; Young, RA; - view fewer (2017) Small genomic insertions form enhancers that misregulate oncogenes. Nature Communications , 8 , Article 14385. 10.1038/ncomms14385.

Abrol, E; Groszmann, M; Pitman, A; Hough, R; Taylor, RM; Aref-Adib, G; (2017) Exploring the digital technology preferences of teenagers and young adults (TYA) with cancer and survivors: a cross-sectional service evaluation questionnaire. Journal of Cancer Survivorship , 11 (6) pp. 670-682. 10.1007/s11764-017-0618-z.

Afaq, A; Fraioli, F; Sidhu, H; Wan, S; Punwani, S; Chen, S-H; Akin, O; ... Kayani, I; + view all Afaq, A; Fraioli, F; Sidhu, H; Wan, S; Punwani, S; Chen, S-H; Akin, O; Linch, D; Ardeshna, K; Lambert, J; Miles, K; Groves, A; Kayani, I; - view fewer (2017) Comparison of PET/MRI With PET/CT in the Evaluation of Disease Status in Lymphoma. Clinical Nuclear Medicine , 42 (1) e1-e7. 10.1097/RLU.0000000000001344.

Ahern, AL; Wheeler, GM; Aveyard, P; Boyland, EJ; Halford, JCG; Mander, AP; Woolston, J; ... Jebb, SA; + view all Ahern, AL; Wheeler, GM; Aveyard, P; Boyland, EJ; Halford, JCG; Mander, AP; Woolston, J; Thomson, AM; Tsiountsioura, M; Cole, D; Mead, BR; Irvine, L; Turner, D; Suhrcke, M; Pimpin, L; Retat, L; Jaccard, A; Webber, L; Cohn, SR; Jebb, SA; - view fewer (2017) Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial. The Lancet , 389 (10085) pp. 2214-2225. 10.1016/S0140-6736(17)30647-5.

Ali, A; Gale, RE; Shakoori, AR; (2017) Detection of FLT3/TKD and IDH1 Mutations in Pakistani Acute Myeloid Leukemia Patients by Denaturing HPLC. Journal of Cellular Biochemistry , 118 (5) pp. 1174-1181. 10.1002/jcb.25761.

Amaral, AJ; Andrade, J; Foxall, RB; Matoso, P; Matos, AM; Soares, RS; Rocha, C; ... Sousa, AE; + view all Amaral, AJ; Andrade, J; Foxall, RB; Matoso, P; Matos, AM; Soares, RS; Rocha, C; Ramos, CG; Tendeiro, R; Serra-Caetano, A; Guerra-Assunção, JA; Santa-Marta, M; Gonçalves, J; Gama-Carvalho, M; Sousa, AE; - view fewer (2017) miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication. The EMBO Journal , 36 (3) pp. 346-360. 10.15252/embj.201694335.

Amary, F; Berisha, F; Ye, H; Gupta, M; Gutteridge, A; Baumhoer, D; Gibbons, R; ... Flanagan, AM; + view all Amary, F; Berisha, F; Ye, H; Gupta, M; Gutteridge, A; Baumhoer, D; Gibbons, R; Tirabosco, R; O'Donnell, P; Flanagan, AM; - view fewer (2017) H3F3A (Histone 3.3) G34W Immunohistochemistry: A Reliable Marker Defining Benign and Malignant Giant Cell Tumor of Bone. American Journal of Surgical Pathology , 41 (8) pp. 1059-1068. 10.1097/PAS.0000000000000859.

Amary, F; Pillay, N; Flanagan, AM; (2017) Molecular testing of sarcomas. Diagnostic Histopathology , 23 (10) pp. 431-441. 10.1016/j.mpdhp.2017.08.003.

Amodeo, V; A, D; Betts, J; Bartesaghi, S; Zhang, Y; Richard-Londt, A; Ellis, M; ... Salomoni, P; + view all Amodeo, V; A, D; Betts, J; Bartesaghi, S; Zhang, Y; Richard-Londt, A; Ellis, M; Roshani, R; Vouri, M; Galavotti, S; Oberndorfer, S; Leite, AP; Mackay, A; Lampada, A; Wessel Stratford, E; Li, N; Dinsdale, D; Grimwade, D; Jones, C; Nicotera, P; Michod, D; Brandner, S; Salomoni, P; - view fewer (2017) A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS. Cell Reports , 20 (2) pp. 411-426. 10.1016/j.celrep.2017.06.047.

Angelis, A; Montibeller, G; Hochhauser, D; Kanavos, P; (2017) Multiple criteria decision analysis in the context of health technology assessment: a simulation exercise on metastatic colorectal cancer with multiple stakeholders in the English setting. BMC Medical Informatics and Decision Making , 17 (1) , Article 149. 10.1186/s12911-017-0524-3.

Ansari, T; Lange, P; Southgate, A; Greco, K; Carvalho, C; Partington, L; Bullock, A; ... Birchall, MA; + view all Ansari, T; Lange, P; Southgate, A; Greco, K; Carvalho, C; Partington, L; Bullock, A; MacNeil, S; Lowdell, MW; Sibbons, PD; Birchall, MA; - view fewer (2017) Stem Cell-Based Tissue-Engineered Laryngeal Replacement. Stem Cells Translational Medicine , 6 (2) pp. 677-687. 10.5966/sctm.2016-0130.

Arends, M; Biegstraaten, M; Hughes, DA; Mehta, A; Elliott, PM; Oder, D; Watkinson, OT; ... Hollak, CEM; + view all Arends, M; Biegstraaten, M; Hughes, DA; Mehta, A; Elliott, PM; Oder, D; Watkinson, OT; Vaz, FM; van Kuilenburg, ABP; Wanner, C; Hollak, CEM; - view fewer (2017) Retrospective study of long-term outcomes of enzyme replacement therapy in Fabry disease: Analysis of prognostic factors. PLoS One , 12 (8) , Article e0182379. 10.1371/journal.pone.0182379.

Arends, M; Körver, S; Hughes, DA; Mehta, A; Hollak, CEM; Biegstraaten, M; (2017) Phenotype, disease severity and pain are major determinants of quality of life in Fabry disease: results from a large multicenter cohort study. J Inherit Metab Dis 10.1007/s10545-017-0095-6. (In press).

Armstrong, CA; Moiseeva, V; Collopy, LC; Pearson, SR; Ullah, TR; Xi, ST; Martin, J; ... Tomita, K; + view all Armstrong, CA; Moiseeva, V; Collopy, LC; Pearson, SR; Ullah, TR; Xi, ST; Martin, J; Subramaniam, S; Marelli, S; Amelina, H; Tomita, K; - view fewer (2017) Fission yeast Ccq1 is a modulator of telomerase activity. Nucleic Acids Res 10.1093/nar/gkx1223. (In press).

Armstrong, CA; Tomita, K; (2017) Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells. Open Biology , 7 (3) , Article 160338. 10.1098/rsob.160338.

Artim-Esen, B; Smoktunowicz, N; McDonnell, T; Ripoll, VM; Pericleous, C; Mackie, I; Robinson, E; ... Giles, I; + view all Artim-Esen, B; Smoktunowicz, N; McDonnell, T; Ripoll, VM; Pericleous, C; Mackie, I; Robinson, E; Isenberg, D; Rahman, A; Ioannou, Y; Chambers, RC; Giles, I; - view fewer (2017) Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome. Scientific Reports , 7 (1) , Article 10788. 10.1038/s41598-017-11315-9.

Atsamnia, D; Hamadache, M; Hanini, S; Benkortbi, O; Oukrif, D; (2017) Prediction of the antibacterial activity of garlic extract on E. coli, S. aureus and B. subtilis by determining the diameter of the inhibition zones using artificial neural networks. LWT - Food Science and Technology , 82 pp. 287-295. 10.1016/j.lwt.2017.04.053.

Baker, A-M; Huang, W; Wang, X-MM; Jansen, M; Ma, X-J; Kim, J; Anderson, CM; ... Graham, TA; + view all Baker, A-M; Huang, W; Wang, X-MM; Jansen, M; Ma, X-J; Kim, J; Anderson, CM; Wu, X; Pan, L; Su, N; Luo, Y; Domingo, E; Heide, T; Sottoriva, A; Lewis, A; Beggs, AD; Wright, NA; Rodriguez-Justo, M; Park, E; Tomlinson, I; Graham, TA; - view fewer (2017) Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution. Nature Communications , 8 , Article 1998. 10.1038/s41467-017-02295-5.

Banerjee, G; Wilson, D; Ambler, G; Osei-Bonsu Appiah, K; Shakeshaft, C; Lunawat, S; Cohen, H; ... CROMIS-2 Collaborators; + view all Banerjee, G; Wilson, D; Ambler, G; Osei-Bonsu Appiah, K; Shakeshaft, C; Lunawat, S; Cohen, H; Yousry, T; Lip, GYH; Muir, KW; Brown, MM; Al-Shahi Salman, R; Jäger, HR; Werring, DJ; CROMIS-2 Collaborators; - view fewer (2017) Cognitive Impairment Before Intracerebral Hemorrhage Is Associated With Cerebral Amyloid Angiopathy. Stroke , 49 pp. 40-45. 10.1161/STROKEAHA.117.019409.

Barbieri, CE; Chinnaiyan, AM; Lerner, SP; Swanton, C; Rubin, MA; (2017) The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics. European Urology , 71 (2) pp. 237-246. 10.1016/j.eururo.2016.08.024.

Barrett, JE; Feber, A; Herrero, J; Tanic, M; Wilson, GA; Swanton, C; Beck, S; (2017) Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection. BMC Bioinformatics , 18 , Article 354. 10.1186/s12859-017-1753-2.

Barrington, C; Finn, R; Hadjur, S; (2017) Cohesin biology meets the loop extrusion model. Chromosome Research , 25 (1) pp. 51-60. 10.1007/s10577-017-9550-3.

Barrington, C; Pezic, D; Hadjur, S; (2017) Chromosome structure dynamics during the cell cycle: a structure to fit every phase. The EMBO Journal , 36 (17) , Article e201798014. 10.15252/embj.201798014.

Behe, P; Foote, JR; Levine, AP; Platt, CD; Chou, J; Benavides, F; Geha, RS; Behe, P; Foote, JR; Levine, AP; Platt, CD; Chou, J; Benavides, F; Geha, RS; Segal, AW; - view fewer (2017) The LRRC8A Mediated "Swell Activated" Chloride Conductance Is Dispensable for Vacuolar Homeostasis in Neutrophils. Frontiers in Pharmacology , 8 , Article 262. 10.3389/fphar.2017.00262.

Behjati, S; Tarpey, PS; Haase, K; Ye, H; Young, MD; Alexandrov, LB; Farndon, SJ; ... Campbell, PJ; + view all Behjati, S; Tarpey, PS; Haase, K; Ye, H; Young, MD; Alexandrov, LB; Farndon, SJ; Collord, G; Wedge, DC; Martincorena, I; Cooke, SL; Davies, H; Mifsud, W; Lidgren, M; Martin, S; Latimer, C; Maddison, M; Butler, AP; Teague, JW; Pillay, N; Shlien, A; McDermott, U; Futreal, PA; Baumhoer, D; Zaikova, O; Bjerkehagen, B; Myklebost, O; Amary, MF; Tirabosco, R; Van Loo, P; Stratton, MR; Flanagan, AM; Campbell, PJ; - view fewer (2017) Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma. Nature Communications , 8 , Article 15936. 10.1038/ncomms15936.

Bekers, EM; Groenen, PJTA; Verdijk, MAJ; Raaijmakers-van Geloof, WL; Roepman, P; Vink, R; Gilhuijs, NDB; ... Flucke, U; + view all Bekers, EM; Groenen, PJTA; Verdijk, MAJ; Raaijmakers-van Geloof, WL; Roepman, P; Vink, R; Gilhuijs, NDB; van Gorp, JM; Bovee, JVMG; Creytens, DH; Flanagan, AM; Suurmeijer, AJH; Mentzel, T; Arbajian, E; Flucke, U; - view fewer (2017) Soft tissue angiofibroma: Clinicopathologic, immunohistochemical and molecular analysis of 14 cases. Genes Chromosomes & Cancer , 56 (10) pp. 750-757. 10.1002/gcc.22478.

Belmatoug, N; Di Rocco, M; Fraga, C; Giraldo, P; Hughes, D; Lukina, E; Maison-Blanche, P; ... Cox, TM; + view all Belmatoug, N; Di Rocco, M; Fraga, C; Giraldo, P; Hughes, D; Lukina, E; Maison-Blanche, P; Merkel, M; Niederau, C; Plockinger, U; Richter, J; Stulnig, TM; Dahl, SV; Cox, TM; - view fewer (2017) Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe. [Review]. European Journal of Internal Medicine , 37 pp. 25-32. 10.1016/j.ejim.2016.07.011.

Benjamin, ER; Della Valle, MC; Wu, X; Katz, E; Pruthi, F; Bond, S; Bronfin, B; ... Lockhart, DJ; + view all Benjamin, ER; Della Valle, MC; Wu, X; Katz, E; Pruthi, F; Bond, S; Bronfin, B; Williams, H; Yu, J; Bichet, DG; Germain, DP; Giugliani, R; Hughes, D; Schiffmann, R; Wilcox, WR; Desnick, RJ; Kirk, J; Barth, J; Barlow, C; Valenzano, KJ; Castelli, J; Lockhart, DJ; - view fewer (2017) The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat. Genetics in Medicine , 19 (4) pp. 430-438. 10.1038/gim.2016.122.

Bentham, RB; Bryson, K; Szabadkai, G; (2017) MCbiclust: a novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections. Nucleic Acids Research , 45 (15) pp. 8712-8730. 10.1093/nar/gkx590.

Berenjeno, IM; Piñeiro, R; Castillo, SD; Pearce, W; McGranahan, N; Dewhurst, SM; Meniel, V; ... Vanhaesebroeck, B; + view all Berenjeno, IM; Piñeiro, R; Castillo, SD; Pearce, W; McGranahan, N; Dewhurst, SM; Meniel, V; Birkbak, NJ; Lau, E; Sansregret, L; Morelli, D; Kanu, N; Srinivas, S; Graupera, M; Parker, VER; Montgomery, KG; Moniz, LS; Scudamore, CL; Phillips, WA; Semple, RK; Clarke, A; Swanton, C; Vanhaesebroeck, B; - view fewer (2017) Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications , 8 , Article 1773. 10.1038/s41467-017-02002-4.

Berlato, C; Khan, MN; Schioppa, T; Thompson, R; Maniati, E; Montfort, A; Jangani, M; ... Balkwill, FR; + view all Berlato, C; Khan, MN; Schioppa, T; Thompson, R; Maniati, E; Montfort, A; Jangani, M; Canosa, M; Kulbe, H; Hagemann, UB; Duncan, AR; Fletcher, L; Wilkinson, RW; Powles, T; Quezada, SA; Balkwill, FR; - view fewer (2017) A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. Journal of Clinical Investigation , 127 (3) pp. 801-813. 10.1172/JCI82976.

Bernatsky, S; Velásquez García, HA; Spinelli, JJ; Gaffney, P; Smedby, KE; Ramsey-Goldman, R; Wang, SS; ... Clarke, AE; + view all Bernatsky, S; Velásquez García, HA; Spinelli, JJ; Gaffney, P; Smedby, KE; Ramsey-Goldman, R; Wang, SS; Adami, H-O; Albanes, D; Angelucci, E; Ansell, SM; Asmann, YW; Becker, N; Benavente, Y; Berndt, SI; Bertrand, KA; Birmann, BM; Boeing, H; Boffetta, P; Bracci, PM; Brennan, P; Brooks-Wilson, AR; Cerhan, JR; Chanock, SJ; Clavel, J; Conde, L; Cotenbader, KH; Cox, DG; Cozen, W; Crouch, S; De Roos, AJ; de Sanjose, S; Di Lollo, S; Diver, WR; Dogan, A; Foretova, L; Ghesquières, H; Giles, GG; Glimelius, B; Habermann, TM; Haioun, C; Hartge, P; Hjalgrim, H; Holford, TR; Holly, EA; Jackson, RD; Kaaks, R; Kane, E; Kelly, RS; Klein, RJ; Kraft, P; Kricker, A; Lan, Q; Lawrence, C; Liebow, M; Lightfoot, T; Link, BK; Maynadie, M; McKay, J; Melbye, M; Molina, TJ; Monnereau, A; Morton, LM; Nieters, A; North, KE; Novak, AJ; Offit, K; Purdue, MP; Rais, M; Riby, J; Roman, E; Rothman, N; Salles, G; Severi, G; Severson, RK; Skibola, CF; Slager, SL; Smith, A; Smith, MT; Southey, MC; Staines, A; Teras, LR; Thompson, CA; Tilly, H; Tinker, LF; Tjonneland, A; Turner, J; Vajdic, CM; Vermeulen, RCH; Vijai, J; Vineis, P; Virtamo, J; Wang, Z; Weinstein, S; Witzig, TE; Zelenetz, A; Zeleniuch-Jacquotte, A; Zhang, Y; Zheng, T; Zucca, M; Clarke, AE; - view fewer (2017) Lupus-related single nucleotide polymorphisms and risk of diffuse large B-cell lymphoma. Lupus Sci Med , 4 (1) , Article e000187. 10.1136/lupus-2016-000187.

Bharucha, T; Rutherford, A; Skeoch, S; Alavi, A; Brown, M; Galloway, J; FDG-PET/CT in fever of unknown origin working group; (2017) Diagnostic yield of FDG-PET/CT in fever of unknown origin: a systematic review, meta-analysis, and Delphi exercise. Clinical Radiology , 72 (9) pp. 764-771. 10.1016/j.crad.2017.04.014.

Bilancio, A; Rinaldi, B; Oliviero, MA; Donniacuo, M; Monti, MG; Boscaino, A; Marino, I; ... Migliaccio, A; + view all Bilancio, A; Rinaldi, B; Oliviero, MA; Donniacuo, M; Monti, MG; Boscaino, A; Marino, I; Friedman, L; Rossi, F; Vanhaesebroeck, B; Migliaccio, A; - view fewer (2017) Inhibition of p110δ PI3K prevents inflammatory response and restenosis after artery injury. Bioscience Reports , 37 (5) , Article BSR20171112. 10.1042/BSR20171112.

Bilanges, B; Alliouachene, S; Pearce, W; Morelli, D; Szabadkai, G; Chung, Y-L; Chicanne, G; ... Vanhaesebroeck, B; + view all Bilanges, B; Alliouachene, S; Pearce, W; Morelli, D; Szabadkai, G; Chung, Y-L; Chicanne, G; Valet, C; Hill, JM; Voshol, PJ; Collinson, L; Peddie, C; Ali, K; Ghazaly, E; Rajeeve, V; Trichas, G; Srinivas, S; Chaussade, C; Salamon, RS; Backer, JM; Scudamore, CL; Whitehead, MA; Keaney, EP; Murphy, LO; Semple, RK; Payrastre, B; Tooze, SA; Vanhaesebroeck, B; - view fewer (2017) Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism. Nature Communications , 8 , Article 1804. 10.1038/s41467-017-01969-4.

Billen, A; Madrigal, JA; Scior, K; Shaw, BE; Strydom, A; (2017) Donation of peripheral blood stem cells to unrelated strangers: A thematic analysis. PLoS ONE , 12 (10) , Article e0186438. 10.1371/journal.pone.0186438.

Bird, S; Hadjimichael, E; Mehta, A; Ramaswami, U; Hughes, D; (2017) Fabry disease and incidence of cancer. Orphanet Journal of Rare Diseases , 12 (1) , Article 150. 10.1186/s13023-017-0701-6.

Blakely, CM; Watkins, TBK; Wu, W; Gini, B; Chabon, JJ; McCoach, CE; McGranahan, N; ... Bivona, TG; + view all Blakely, CM; Watkins, TBK; Wu, W; Gini, B; Chabon, JJ; McCoach, CE; McGranahan, N; Wilson, GA; Birkbak, NJ; Olivas, VR; Rotow, J; Maynard, A; Wang, V; Gubens, MA; Banks, KC; Lanman, RB; Caulin, AF; St John, J; Cordero, AR; Giannikopoulos, P; Simmons, AD; Mack, PC; Gandara, DR; Husain, H; Doebele, RC; Riess, JW; Diehn, M; Swanton, C; Bivona, TG; - view fewer (2017) Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nature Genetics , 49 (12) pp. 1693-1704. 10.1038/ng.3990.

Boege, Y; Malehmir, M; Healy, ME; Bettermann, K; Lorentzen, A; Vucur, M; Ahuja, AK; ... Weber, A; + view all Boege, Y; Malehmir, M; Healy, ME; Bettermann, K; Lorentzen, A; Vucur, M; Ahuja, AK; Böhm, F; Mertens, JC; Shimizu, Y; Frick, L; Remouchamps, C; Mutreja, K; Kähne, T; Sundaravinayagam, D; Wolf, MJ; Rehrauer, H; Koppe, C; Speicher, T; Padrissa-Altés, S; Maire, R; Schattenberg, JRM; Jeong, J-S; Liu, L; Zwirner, S; Boger, R; Hüser, N; Davis, RJ; Müllhaupt, B; Moch, H; Schulze-Bergkamen, H; Clavien, P-A; Werner, S; Borsig, L; Luther, SA; Jost, PJ; Weinlich, R; Unger, K; Behrens, A; Hillert, L; Dillon, C; Di Virgilio, M; Wallach, D; Dejardin, E; Zender, L; Naumann, M; Walczak, H; Green, DR; Lopes, M; Lavrik, I; Luedde, T; Heikenwalder, M; Weber, A; - view fewer (2017) A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell , 32 (3) pp. 342-359. 10.1016/j.ccell.2017.08.010.

Bookman, MA; Okamoto, A; Stuart, G; Yanaihara, N; Aoki, D; Bacon, M; Fujiwara, K; ... Ochiai, K; + view all Bookman, MA; Okamoto, A; Stuart, G; Yanaihara, N; Aoki, D; Bacon, M; Fujiwara, K; Gonzalez-Martin, A; Harter, P; Kim, JW; Ledermann, J; Pujade-Lauraine, E; Quinn, M; Ochiai, K; - view fewer (2017) Harmonising clinical trials within the Gynecologic Cancer InterGroup: consensus and unmet needs from the Fifth Ovarian Cancer Consensus Conference. Annals of Oncology , 28 (S8) viii30-viii35. 10.1093/annonc/mdx449.

Bosch-Vilaro, A; Jacobs, B; Pomella, V; Asbagh, LA; Kirkland, R; Michel, J; Singh, S; ... Tejpar, S; + view all Bosch-Vilaro, A; Jacobs, B; Pomella, V; Asbagh, LA; Kirkland, R; Michel, J; Singh, S; Liu, X; Kim, P; Weitsman, G; Barber, PR; Vojnovic, B; Ng, T; Tejpar, S; - view fewer (2017) Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells. Oncotarget , 8 (3) pp. 4277-4288. 10.18632/oncotarget.13834.

Boto, C; Quartin, E; Cai, Y; Martin-Lorenzo, A; Garcia Cenador, MB; Pinto, S; Gupta, R; ... Ferreira, L; + view all Boto, C; Quartin, E; Cai, Y; Martin-Lorenzo, A; Garcia Cenador, MB; Pinto, S; Gupta, R; Enver, T; Sanchez-Garcia, I; Hong, D; das Neves, RP; Ferreira, L; - view fewer (2017) Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation. Nature Communications , 8 , Article 15204. 10.1038/ncomms15204.

Bray, TJP; Singh, S; Latifoltojar, A; Rajesparan, K; Rahman, F; Narayanan, P; Naaseri, S; ... Hall-Craggs, MA; + view all Bray, TJP; Singh, S; Latifoltojar, A; Rajesparan, K; Rahman, F; Narayanan, P; Naaseri, S; Lopes, A; Bainbridge, A; Punwani, S; Hall-Craggs, MA; - view fewer (2017) Diagnostic utility of whole body Dixon MRI in multiple myeloma: A multi-reader study. PLoS One , 12 (7) , Article e0180562. 10.1371/journal.pone.0180562.

Brooks, L; Viardot, A; Tsakmaki, A; Stolarczyk, E; Howard, JK; Cani, PD; Everard, A; ... Bewick, GA; + view all Brooks, L; Viardot, A; Tsakmaki, A; Stolarczyk, E; Howard, JK; Cani, PD; Everard, A; Sleeth, ML; Psichas, A; Anastasovskaj, J; Bell, JD; Bell-Anderson, K; Mackay, CR; Ghatei, MA; Bloom, SR; Frost, G; Bewick, GA; - view fewer (2017) Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety. Molecular Metabolism , 6 (1) pp. 48-60. 10.1016/j.molmet.2016.10.011.

Brooks, LJ; Parrinello, S; (2017) Vascular regulation of glioma stem-like cells: a balancing act. Current Opinion in Neurobiology , 47 pp. 8-15. 10.1016/j.conb.2017.06.008.

Brown, N; Carter, T; Mulholland, P; (2017) Adjuvant Chemotherapy is Indicated in Patients with Lower Grade Glioma. Clinical Oncology , 29 (3) pp. 141-142. 10.1016/j.clon.2016.11.006.

Brown, NF; Carter, T; Kitchen, N; Mulholland, P; (2017) Dabrafenib and trametinib in BRAFV600E mutated glioma. CNS Oncology , 6 (4) 10.2217/cns-2017-0006.

Brown, NF; Carter, T; Mulholland, P; (2017) Dabrafenib in BRAFV600-mutated anaplastic pleomorphic xanthoastrocytoma. CNS Oncology , 6 (1) 10.2217/cns-2016-0031.

Browning, RJ; Reardon, PJT; Parhizkar, M; Pedley, RB; Edirisinghe, M; Knowles, JC; Stride, E; (2017) Drug Delivery Strategies for Platinum Based Chemotherapy. ACS Nano , 11 (9) pp. 8560-8578. 10.1021/acsnano.7b04092.

Budin-Ljøsne, I; Teare, HJ; Kaye, J; Beck, S; Bentzen, HB; Caenazzo, L; Collett, C; ... Mascalzoni, D; + view all Budin-Ljøsne, I; Teare, HJ; Kaye, J; Beck, S; Bentzen, HB; Caenazzo, L; Collett, C; D'Abramo, F; Felzmann, H; Finlay, T; Javaid, MK; Jones, E; Katić, V; Simpson, A; Mascalzoni, D; - view fewer (2017) Dynamic Consent: a potential solution to some of the challenges of modern biomedical research. BMC Medical Ethics , 18 , Article 4. 10.1186/s12910-016-0162-9.

Butcher, LM; Beck, S; (2017) Nano-MeDIP-seq Methylome Analysis Using Low DNA Concentrations. Methods in Molecular Biology: Population Epigenetics , 1589 pp. 115-138. 10.1007/7651_2015_259.

Butler, CR; Hynds, RE; Crowley, C; Gowers, KH; Partington, L; Hamilton, NJ; Carvalho, C; ... Janes, SM; + view all Butler, CR; Hynds, RE; Crowley, C; Gowers, KH; Partington, L; Hamilton, NJ; Carvalho, C; Platé, M; Samuel, ER; Burns, AJ; Urbani, L; Birchall, MA; Lowdell, MW; De Coppi, P; Janes, SM; - view fewer (2017) Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds. Biomaterials , 124 pp. 95-105. 10.1016/j.biomaterials.2017.02.001.

Butt, MA; Pye, H; Haidry, RJ; Oukrif, D; Khan, SU; Puccio, I; Gandy, M; ... Lovat, LB; + view all Butt, MA; Pye, H; Haidry, RJ; Oukrif, D; Khan, SU; Puccio, I; Gandy, M; Reinert, HW; Bloom, E; Rashid, M; Yahioglu, G; Deonarain, MP; Hamoudi, R; Rodriguez-Justo, M; Novelli, MR; Lovat, LB; - view fewer (2017) Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate. Oncotarget , 8 pp. 25080-25096. 10.18632/oncotarget.15340.

Byrne, BJ; Geberhiwot, T; Barshop, BA; Barohn, R; Hughes, D; Bratkovic, D; Desnuelle, C; ... Walsh, L; + view all Byrne, BJ; Geberhiwot, T; Barshop, BA; Barohn, R; Hughes, D; Bratkovic, D; Desnuelle, C; Laforet, P; Mengel, E; Roberts, M; Haroldsen, P; Reilley, K; Jayaram, K; Yang, K; Walsh, L; - view fewer (2017) A study on the safety and efficacy of reveglucosidase alfa in patients with late-onset Pompe disease. Orphanet Journal of Rare Diseases , 12 , Article 144. 10.1186/s13023-017-0693-2.

Calvo, E; Moreno, V; Flynn, M; Holgado, E; Olmedo, ME; Criado, MPL; Kahatt, C; ... Forster, M; + view all Calvo, E; Moreno, V; Flynn, M; Holgado, E; Olmedo, ME; Criado, MPL; Kahatt, C; Lopez-Vilarino, JA; Siguero, M; Fernandez-Teruel, C; Cullell-Young, M; Matos-Pita, AS; Forster, M; - view fewer (2017) Antitumor activity of lurbinectedin (PM01183) and doxorubicin in relapsed small-cell lung cancer: results from a phase I study. Annals of Oncology , 28 (10) pp. 2559-2566. 10.1093/annonc/mdx357.

Cameron, AJM; Veeriah, S; Marshall, JJT; Murray, ER; Larijani, B; Parker, PJ; (2017) Uncoupling TORC2 from AGC kinases inhibits tumour growth. Oncotarget , 8 (49) pp. 84685-84696. 10.18632/oncotarget.20086.

Campos, WN; Massaro, JD; Martinelli, ALC; Halliwell, JA; Marsh, SGE; Mendes-Junior, CT; Donadi, EA; (2017) HFE gene polymorphism defined by sequence based typing of the Brazilian population and a standardized nomenclature for HFE allele sequences. HLA , 90 (4) pp. 238-242. 10.1111/tan.13097.

Capobianco, A; Cottone, L; Monno, A; Manfredi, AA; Rovere-Querini, P; (2017) The peritoneum: healing, immunity and diseases. The Journal of Pathology , 243 (2) pp. 137-147. 10.1002/path.4942.

Carss, KJ; Arno, G; Erwood, M; Stephens, J; Sanchis-Juan, A; Hull, S; Megy, K; ... Raymond, FL; + view all Carss, KJ; Arno, G; Erwood, M; Stephens, J; Sanchis-Juan, A; Hull, S; Megy, K; Grozeva, D; Dewhurst, E; Malka, S; Plagnol, V; Penkett, C; Stirrups, K; Rizzo, R; Wright, G; Josifova, D; Bitner-Glindzicz, M; Scott, RH; Clement, E; Allen, L; Armstrong, R; Brady, AF; Carmichael, J; Chitre, M; Henderson, RHH; Hurst, J; MacLaren, RE; Murphy, E; Paterson, J; Rosser, E; Thompson, DA; Wakeling, E; Ouwehand, WH; Michaelides, M; Moore, AT; Webster, AR; Raymond, FL; - view fewer (2017) Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease. American Journal of Human Genetics , 100 (1) pp. 75-90. 10.1016/j.ajhg.2016.12.003.

Caswell, DR; Swanton, C; (2017) The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome. [Review]. BMC Medicine , 15 , Article 133. 10.1186/s12916-017-0900-y.

Cavenagh, J; Oakervee, H; Baetiong-Caguioa, P; Davies, F; Gharibo, M; Rabin, N; Kurman, M; ... Yong, K; + view all Cavenagh, J; Oakervee, H; Baetiong-Caguioa, P; Davies, F; Gharibo, M; Rabin, N; Kurman, M; Novak, B; Shiraishi, N; Nakashima, D; Akinaga, S; Yong, K; - view fewer (2017) A phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma. British Journal of Cancer , 117 (9) pp. 1295-1302. 10.1038/bjc.2017.302.

Chan, MMY; Barnicoat, A; Mumtaz, F; Aitchison, M; Side, L; Brittain, H; Bates, AWH; Chan, MMY; Barnicoat, A; Mumtaz, F; Aitchison, M; Side, L; Brittain, H; Bates, AWH; Gale, DP; - view fewer (2017) Cascade Fumarate Hydratase mutation screening allows early detection of kidney tumour: a case report. BMC Medical Genetics , 18 , Article 79. 10.1186/s12881-017-0436-1.

Chandran, S; Watkins, J; Abdul‐Aziz, A; Shafat, M; Calvert, PA; Bowles, KM; Flather, MD; ... Ryding, AD; + view all Chandran, S; Watkins, J; Abdul‐Aziz, A; Shafat, M; Calvert, PA; Bowles, KM; Flather, MD; Rushworth, SA; Ryding, AD; - view fewer (2017) Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST‐Segment Elevation Myocardial Infarction. Journal of the American Heart Association , 6 (5) , Article e005868. 10.1161/JAHA.117.005868.

Cheung, WA; Shao, X; Morin, A; Siroux, V; Kwan, T; Ge, B; Aissi, D; ... Grundberg, E; + view all Cheung, WA; Shao, X; Morin, A; Siroux, V; Kwan, T; Ge, B; Aissi, D; Chen, L; Vasquez, L; Allum, F; Guenard, F; Bouzigon, E; Simon, M-M; Boulier, E; Redensek, A; Watt, S; Datta, A; Clarke, L; Flicek, P; Mead, D; Paul, DS; Beck, S; Bourque, G; Lathrop, M; Tchernof, A; Vohl, M-C; Demenais, F; Pin, I; Downes, K; Stunnenberg, HG; Soranzo, N; Pastinen, T; Grundberg, E; - view fewer (2017) Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biology , 18 , Article 50. 10.1186/s13059-017-1173-7.

Chin, M; Sive, JI; Allen, C; Roddie, C; Chavda, SJ; Smith, D; Blombery, P; ... Yong, KL; + view all Chin, M; Sive, JI; Allen, C; Roddie, C; Chavda, SJ; Smith, D; Blombery, P; Jones, K; Ryland, GL; Popat, R; Rismani, A; D'Sa, S; Rabin, N; Gale, RE; Yong, KL; - view fewer (2017) Prevalence and timing of TP53 mutations in del(17p) myeloma and effect on survival. Blood Cancer Journal , 7 , Article e610. 10.1038/bcj.2017.76.

Choueiri, TK; Plimack, E; Arkenau, H-T; Jonasch, E; Heng, DYC; Powles, T; Frigault, MM; ... Pal, SK; + view all Choueiri, TK; Plimack, E; Arkenau, H-T; Jonasch, E; Heng, DYC; Powles, T; Frigault, MM; Clark, EA; Handzel, AA; Gardner, H; Morgan, S; Albiges, L; Pal, SK; - view fewer (2017) Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer. Journal of Clinical Oncology , 35 (26) pp. 2993-3001. 10.1200/JCO.2017.72.2967.

Cinelli, M; Sun, Y; Best, K; Heather, JM; Reich-Zeliger, S; Shifrut, E; Friedman, N; ... Chain, B; + view all Cinelli, M; Sun, Y; Best, K; Heather, JM; Reich-Zeliger, S; Shifrut, E; Friedman, N; Shawe-Taylor, J; Chain, B; - view fewer (2017) Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires. Bioinformatics , 33 (7) pp. 951-955. 10.1093/bioinformatics/btw771.

Clements, MP; Byrne, E; Camarillo Guerrero, LF; Cattin, A-L; Zakka, L; Ashraf, A; Burden, JJ; ... Parrinello, S; + view all Clements, MP; Byrne, E; Camarillo Guerrero, LF; Cattin, A-L; Zakka, L; Ashraf, A; Burden, JJ; Khadayate, S; Lloyd, AC; Marguerat, S; Parrinello, S; - view fewer (2017) The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration. Neuron , 96 (1) 98-114.e7. 10.1016/j.neuron.2017.09.008.

Coleman, RL; Oza, AM; Lorusso, D; Aghajanian, C; Oaknin, A; Dean, A; Colombo, N; ... ARIEL3 investigators; + view all Coleman, RL; Oza, AM; Lorusso, D; Aghajanian, C; Oaknin, A; Dean, A; Colombo, N; Weberpals, JI; Clamp, A; Scambia, G; Leary, A; Holloway, RW; Gancedo, MA; Fong, PC; Goh, JC; O'Malley, DM; Armstrong, DK; Garcia-Donas, J; Swisher, EM; Floquet, A; Konecny, GE; McNeish, IA; Scott, CL; Cameron, T; Maloney, L; Isaacson, J; Goble, S; Grace, C; Harding, TC; Raponi, M; Sun, J; Lin, KK; Giordano, H; Ledermann, JA; ARIEL3 investigators; - view fewer (2017) Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial. The Lancet , 390 (10106) pp. 1949-1961. 10.1016/S0140-6736(17)32440-6.

Conteduca, V; Wetterskog, D; Sharabiani, MTA; Grande, E; Fernandez-Perez, MP; Jayaram, A; Salvi, S; ... Spanish Oncology Genitourinary Group, .; + view all Conteduca, V; Wetterskog, D; Sharabiani, MTA; Grande, E; Fernandez-Perez, MP; Jayaram, A; Salvi, S; Castellano, D; Romanel, A; Lolli, C; Casadio, V; Gurioli, G; Amadori, D; Font, A; Vazquez-Estevez, S; Gonzalez del Alba, A; Mellado, B; Fernandez-Calvo, O; Mendez-Vidal, MJ; Climent, MA; Duran, I; Gallardo, E; Rodriguez, A; Santander, C; Saez, MI; Puente, J; Tandefelt, DG; Wingate, A; Dearnaley, D; Demichelis, F; De Giorgi, U; Gonzalez-Billalabeitia, E; Attard, G; PREMIERE Collaborators, .; Spanish Oncology Genitourinary Group, .; - view fewer (2017) Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study. Annals of Oncology , 28 (7) pp. 1508-1516. 10.1093/annonc/mdx155.

Cordero, P; Li, J; Nguyen, V; Pombo, J; Maicas, N; Novelli, M; Taylor, PD; ... Oben, JA; + view all Cordero, P; Li, J; Nguyen, V; Pombo, J; Maicas, N; Novelli, M; Taylor, PD; Samuelsson, A-M; Vinciguerra, M; Oben, JA; - view fewer (2017) Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System. Nutrients , 9 (9) , Article 1041. 10.3390/nu9091041.

Corroyer-Dulmont, A; Falzone, N; Kersemans, V; Thompson, J; Allen, DP; Able, S; Kartsonaki, C; ... Vallis, KA; + view all Corroyer-Dulmont, A; Falzone, N; Kersemans, V; Thompson, J; Allen, DP; Able, S; Kartsonaki, C; Malcolm, J; Kinchesh, P; Hill, MA; Vojnovic, B; Smart, SC; Gaze, MN; Vallis, KA; - view fewer (2017) Improved outcome of 131I-mIBG treatment through combination with external beam radiotherapy in the SK-N-SH mouse model of neuroblastoma. Radiotherapy and Oncology , 124 (3) pp. 488-495. 10.1016/j.radonc.2017.05.002.

Corroyer-Dulmont, A; Falzone, N; Kersemans, V; Thompson, J; Hill, M; Danny Allen, P; Beech, J; ... Vallis, KA; + view all Corroyer-Dulmont, A; Falzone, N; Kersemans, V; Thompson, J; Hill, M; Danny Allen, P; Beech, J; Gilchrist, S; Kinchesh, P; Vojnovic, B; Tullis, I; Gaze, MN; Smart, S; Vallis, KA; - view fewer (2017) MRI-guided radiotherapy of the SK-N-SH neuroblastoma xenograft model using a small animal radiation research platform. British Journal of Radiology , 90 (1069) , Article 20160427. 10.1259/bjr.20160427.

Coumbe, BGT; Chandran, JA; Ng, KH; Tomson, J; (2017) An Unusual Case of Acute Stent Thrombosis: A Review of a Rare Cause of Acute Stent Occlusion. Cardiology & Vascular Research , 1 (1) pp. 1-3. 10.33425/2639-8486.1003.

Counsell, N; Biri, D; Fraczek, J; Hackshaw, A; (2017) Publishing interim results of randomised clinical trials in peer-reviewed journals. Clinical Trials , 14 (1) pp. 67-77. 10.1177/1740774516664689.

Cox, S; Hurt, C; Grenader, T; Mukherjee, S; Bridgewater, J; Crosby, T; (2017) The prognostic value of derived neutrophil to lymphocyte ratio in oesophageal cancer treated with definitive chemoradiotherapy. Radiotherapy and Oncology , 125 (1) pp. 154-159. 10.1016/j.radonc.2017.08.023.

Crockford, A; Zalmas, LP; Grönroos, E; Dewhurst, SM; McGranahan, N; Cuomo, ME; Encheva, V; ... Swanton, C; + view all Crockford, A; Zalmas, LP; Grönroos, E; Dewhurst, SM; McGranahan, N; Cuomo, ME; Encheva, V; Snijders, AP; Begum, J; Purewal, S; Cerveira, J; Patel, H; Renshaw, MJ; Swanton, C; - view fewer (2017) Cyclin D mediates tolerance of genome-doubling in cancers with functional p53. Annals of Oncology , 28 (1) pp. 149-156. 10.1093/annonc/mdw612.

Crolley, VE; Gibbins, N; (2017) One hundred years of external approach medialisation thyroplasty. Journal of Laryngology and Otology , 131 (3) pp. 202-208. 10.1017/S0022215116010033.

Crosby, T; Hurt, CN; Falk, S; Gollins, S; Staffurth, J; Ray, R; Bridgewater, JA; ... Mukherjee, S; + view all Crosby, T; Hurt, CN; Falk, S; Gollins, S; Staffurth, J; Ray, R; Bridgewater, JA; Geh, JI; Cunningham, D; Blazeby, J; Roy, R; Maughan, T; Griffiths, G; Mukherjee, S; - view fewer (2017) Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/- cetuximab in oesophageal cancer. British Journal of Cancer , 116 pp. 709-716. 10.1038/bjc.2017.21.

Davidson, SM; Riquelme, JA; Takov, K; Vicencio, JM; Boi-Doku, C; Khoo, V; Doreth, C; ... Yellon, DM; + view all Davidson, SM; Riquelme, JA; Takov, K; Vicencio, JM; Boi-Doku, C; Khoo, V; Doreth, C; Radenkovic, D; Lavandero, S; Yellon, DM; - view fewer (2017) Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro. Journal of Cellular and Molecular Medicine 10.1111/jcmm.13302. (In press).

Davis, BA; Allard, S; Qureshi, A; Porter, JB; Pancham, S; Win, N; Cho, G; ... British Society for Haematology, .; + view all Davis, BA; Allard, S; Qureshi, A; Porter, JB; Pancham, S; Win, N; Cho, G; Ryan, K; British Society for Haematology, .; - view fewer (2017) Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion. British Journal of Haematology , 176 (2) pp. 192-209. 10.1111/bjh.14383.

de la Rosa, R; Steinmaus, C; Akers, NK; Conde, L; Ferreccio, C; Kalman, D; Zhang, KR; ... Smith, MT; + view all de la Rosa, R; Steinmaus, C; Akers, NK; Conde, L; Ferreccio, C; Kalman, D; Zhang, KR; Skibola, CF; Smith, AH; Zhang, L; Smith, MT; - view fewer (2017) Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population. Environmental and Molecular Mutagenesis , 58 (6) pp. 411-422. 10.1002/em.22104.

Dehbi, H-M; Royston, P; Hackshaw, A; (2017) Life expectancy difference and life expectancy ratio: two measures of treatment effects in randomised trials with non-proportional hazards. BMJ (357) , Article j2250. 10.1136/bmj.j2250.

Diamond, JR; Goff, B; Forster, MD; Bendell, JC; Britten, CD; Gordon, MS; Gabra, H; ... Moore, KM; + view all Diamond, JR; Goff, B; Forster, MD; Bendell, JC; Britten, CD; Gordon, MS; Gabra, H; Waterhouse, DM; Poole, M; Camidge, DR; Hamilton, E; Moore, KM; - view fewer (2017) Phase Ib study of the mitochondrial inhibitor ME-344 plus topotecan in patients with previously treated, locally advanced or metastatic small cell lung, ovarian and cervical cancers. Investigational New Drugs , 35 (5) pp. 627-633. 10.1007/s10637-017-0444-1.

Dias, J; Axelband, F; Lara, LS; Muzi-Filho, H; Vieyra, A; (2017) Is angiotensin-(3–4) (Val-Tyr), the shortest angiotensin II-derived peptide, opening new vistas on the renin–angiotensin system? Journal of the Renin-Angiotensin-Aldosterone System , 18 (1) 10.1177/1470320316689338.

Dikaios, N; Atkinson, D; Tudisca, C; Purpura, P; Forster, M; Ahmed, H; Beale, T; ... Punwani, S; + view all Dikaios, N; Atkinson, D; Tudisca, C; Purpura, P; Forster, M; Ahmed, H; Beale, T; Emberton, M; Punwani, S; - view fewer (2017) A comparison of Bayesian and non-linear regression methods for robust estimation of pharmacokinetics in DCE-MRI and how it affects cancer diagnosis. Computerized Medical Imaging and Graphics , 56 pp. 1-10. 10.1016/j.compmedimag.2017.01.003.

Diocou, S; Volpe, A; Jauregui-Osoro, M; Boudjemeline, M; Chuamsaamarkkee, K; Man, F; Blower, PJ; ... Fruhwirth, GO; + view all Diocou, S; Volpe, A; Jauregui-Osoro, M; Boudjemeline, M; Chuamsaamarkkee, K; Man, F; Blower, PJ; Ng, T; Mullen, GED; Fruhwirth, GO; - view fewer (2017) [(18)F]tetrafluoroborate-PET/CT enables sensitive tumor and metastasis in vivo imaging in a sodium iodide symporter-expressing tumor model. Scientific Reports , 7 , Article 946. 10.1038/s41598-017-01044-4.

Domingues, PH; Nanduri, LSY; Seget, K; Venkateswaran, SV; Agorku, D; Vigano, C; von Schubert, C; ... Hardt, O; + view all Domingues, PH; Nanduri, LSY; Seget, K; Venkateswaran, SV; Agorku, D; Vigano, C; von Schubert, C; Nigg, EA; Swanton, C; Sotillo, R; Bosio, A; Storchova, Z; Hardt, O; - view fewer (2017) Cellular Prion Protein PrPC and Ecto-5′-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy. Cancer Research , 77 (11) pp. 2914-2926. 10.1158/0008-5472.CAN-16-3052.

Domogala, A; Blundell, M; Thrasher, A; Lowdell, MW; Madrigal, JA; Saudemont, A; (2017) Natural killer cells differentiated in vitro from cord blood CD34(+) cells are more advantageous for use as an immunotherapy than peripheral blood and cord blood natural killer cells. Cytotherapy , 19 (6) pp. 710-720. 10.1016/j.jcyt.2017.03.068.

Dougherty, BA; Lai, Z; Hodgson, DR; Orr, MCM; Hawryluk, M; Sun, J; Yelensky, R; ... Barrett, JC; + view all Dougherty, BA; Lai, Z; Hodgson, DR; Orr, MCM; Hawryluk, M; Sun, J; Yelensky, R; Spencer, SK; Robertson, JD; Ho, TW; Fielding, A; Ledermann, JA; Barrett, JC; - view fewer (2017) Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting. Oncotarget , 8 (27) pp. 43653-43661. 10.18632/oncotarget.17613.

Ecker, S; Beck, S; (2017) Epigenetic variation taking center stage in immunological research. Epigenomics , 9 (4) pp. 375-378. 10.2217/epi-2017-0006.

Ecker, S; Chen, L; Pancaldi, V; Bagger, FO; Fernández, JM; Carrillo de Santa Pau, E; Juan, D; ... Paul, DS; + view all Ecker, S; Chen, L; Pancaldi, V; Bagger, FO; Fernández, JM; Carrillo de Santa Pau, E; Juan, D; Mann, AL; Watt, S; Casale, FP; Sidiropoulos, N; Rapin, N; Merkel, A; BLUEPRINT Consortium, .; Stunnenberg, HG; Stegle, O; Frontini, M; Downes, K; Pastinen, T; Kuijpers, TW; Rico, D; Valencia, A; Beck, S; Soranzo, N; Paul, DS; - view fewer (2017) Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biology , 18 , Article 18. 10.1186/s13059-017-1156-8.

Edeline, J; Blanc, J-F; Campillo-Gimenez, B; Ma, Y-T; King, J; Faluyi, O; Mathurin, J; ... Meyer, T; + view all Edeline, J; Blanc, J-F; Campillo-Gimenez, B; Ma, Y-T; King, J; Faluyi, O; Mathurin, J; Ghazi, S; Palmer, DH; Meyer, T; - view fewer (2017) Prognostic scores for sorafenib-treated hepatocellular carcinoma patients: A new application for the hepatoma arterial embolisation prognostic score. European Journal of Cancer , 86 pp. 135-142. 10.1016/j.ejca.2017.08.036.

Eisenblaetter, M; Flores-Borja, F; Lee, JJ; Wefers, C; Smith, H; Hueting, R; Cooper, MS; ... Ng, T; + view all Eisenblaetter, M; Flores-Borja, F; Lee, JJ; Wefers, C; Smith, H; Hueting, R; Cooper, MS; Blower, PJ; Patel, D; Rodriguez-Justo, M; Milewicz, H; Vogl, T; Roth, J; Tutt, A; Schaeffter, T; Ng, T; - view fewer (2017) Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment. Theranostics , 7 (9) pp. 2392-2401. 10.7150/thno.17138.

El-Khoueiry, AB; Sangro, B; Yau, T; Crocenzi, TS; Kudo, M; Hsu, C; Kim, T-Y; ... Melero, I; + view all El-Khoueiry, AB; Sangro, B; Yau, T; Crocenzi, TS; Kudo, M; Hsu, C; Kim, T-Y; Choo, S-P; Trojan, J; Welling, TH; Meyer, T; Kang, Y-K; Yeo, W; Chopra, A; Anderson, J; Dela Cruz, C; Lang, L; Neely, J; Tang, H; Dastani, HB; Melero, I; - view fewer (2017) Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial. Lancet , 389 (10088) pp. 2492-2502. 10.1016/S0140-6736(17)31046-2.

Elliott, MJ; Butler, CR; Varanou-Jenkins, A; Partington, L; Carvalho, C; Samuel, E; Crowley, C; ... Birchall, MA; + view all Elliott, MJ; Butler, CR; Varanou-Jenkins, A; Partington, L; Carvalho, C; Samuel, E; Crowley, C; Lange, P; Hamilton, NJ; Hynds, RE; Ansari, T; Sibbons, P; Fierens, A; McLaren, C; Roebuck, D; Wallis, C; Muthialu, N; Hewitt, R; Crabbe, D; Janes, SM; De Coppi, P; Lowdell, MW; Birchall, MA; - view fewer (2017) Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine. Stem Cells Translational Medicine , 6 (6) pp. 1458-1464. 10.1002/sctm.16-0443.

Espana-Agusti, J; Warren, A; Chew, SK; Adams, DJ; Matakidou, A; (2017) Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis. Nature Communications , 8 , Article 2026. 10.1038/s41467-017-02245.

Eyre, TA; Phillips, EH; Linton, KM; Kassam, S; Gibb, A; Allibone, S; Radford, J; ... Collins, GP; + view all Eyre, TA; Phillips, EH; Linton, KM; Kassam, S; Gibb, A; Allibone, S; Radford, J; Peggs, K; Burton, C; Stewart, G; LeDieu, R; Booth, C; Osborne, WL; Miall, F; Eyre, DW; Ardeshna, KM; Collins, GP; - view fewer (2017) Results of a multicentre UK-wide retrospective study evaluating the efficacy of brentuximab vedotin in relapsed, refractory classical Hodgkin lymphoma in the transplant naive setting. British Journal of Haematology , 179 (3) pp. 471-479. 10.1111/bjh.14898.

Ezquer, FE; Ezquer, ME; Vicencio, JM; Calligaris, SD; (2017) Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: Increasing transplanted cell resistance and increasing tissue receptivity. Cell Adhesion & Migration , 11 (1) pp. 110-119. 10.1080/19336918.2016.1197480.

Fanale, D; Amodeo, V; Caruso, S; (2017) The Interplay between Metabolism, PPAR Signaling Pathway, and Cancer. PPAR Research , 2017 , Article 1830626. 10.1155/2017/1830626.

Feber, A; Dhami, P; Dong, L; de Winter, P; Tan, WS; Martínez-Fernández, M; Paul, DS; ... Kelly, JD; + view all Feber, A; Dhami, P; Dong, L; de Winter, P; Tan, WS; Martínez-Fernández, M; Paul, DS; Hynes-Allen, A; Rezaee, S; Gurung, P; Rodney, S; Mehmood, A; Villacampa, F; de la Rosa, F; Jameson, C; Cheng, KK; Zeegers, MP; Bryan, RT; James, ND; Paramio, JM; Freeman, A; Beck, S; Kelly, JD; - view fewer (2017) UroMark - a urinary biomarker assay for the detection of bladder cancer. Clinical Epigenetics , 9 , Article 8. 10.1186/s13148-016-0303-5.

Ferolla, P; Brizzi, MP; Meyer, T; Mansoor, W; Mazieres, J; Do Cao, C; Léna, H; ... Baudin, E; + view all Ferolla, P; Brizzi, MP; Meyer, T; Mansoor, W; Mazieres, J; Do Cao, C; Léna, H; Berruti, A; Damiano, V; Buikhuisen, W; Grønbæk, H; Lombard-Bohas, C; Grohé, C; Minotti, V; Tiseo, M; De Castro, J; Reed, N; Gislimberti, G; Singh, N; Stankovic, M; Öberg, K; Baudin, E; - view fewer (2017) Efficacy and safety of long-acting pasireotide or everolimus alone or in combination in patients with advanced carcinoids of the lung and thymus (LUNA): an open-label, multicentre, randomised, phase 2 trial. The Lancet Oncology , 18 (12) pp. 1652-1664. 10.1016/S1470-2045(17)30681-2.

Flanagan, A-M; Stavenschi, E; Basavaraju, S; Gaboriau, D; Hoey, DA; Morrison, CG; (2017) Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification. Molecular Biology of the Cell , 28 (6) pp. 736-745. 10.1091/mbc.E16-05-0325.

Flanagan, AM; Lindsay, D; (2017) A diagnostic approach to bone tumours. Pathology , 49 (7) pp. 675-687. 10.1016/j.pathol.2017.08.003.

Flanagan, AM; Perez-Casanova, L; (2017) Pathology of paediatric bone tumours. Surgery (Oxford) , 35 (1) pp. 2-9. 10.1016/j.mpsur.2016.11.004.

Flux, GD; O'Sullivan, J; Gaze, MN; Prise, KM; (2017) Opportunities for research in molecular radiotherapy. British Journal of Radiology , 90 (1071) , Article 20160921. 10.1259/bjr.20160921.

Flynn, MJ; Hartley, JA; (2017) The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer. [Review]. British Journal of Haematology , 179 (1) pp. 20-35. 10.1111/bjh.14770.

Foote, JR; Behe, P; Frampton, M; Levine, AP; Segal, AW; (2017) An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils. Frontiers in Pharmacology , 8 , Article 94. 10.3389/fphar.2017.00094.

Foote, JR; Levine, AP; Behe, P; Duchen, MR; Segal, AW; (2017) Imaging the Neutrophil Phagosome and Cytoplasm Using a Ratiometric pH Indicator. Journal of Visualized Experiments (122) , Article e55107. 10.3791/55107.

Formica, V; Doldo, E; Antonetti, FR; Nardecchia, A; Ferroni, P; Riondino, S; Morelli, C; ... Roselli, M; + view all Formica, V; Doldo, E; Antonetti, FR; Nardecchia, A; Ferroni, P; Riondino, S; Morelli, C; Arkenau, HT; Guadagni, F; Orlandi, A; Roselli, M; - view fewer (2017) Biological and predictive role of ERCC1 polymorphisms in cancer. Critical Reviews in Oncology/Hematology , 111 pp. 133-143. 10.1016/j.critrevonc.2017.01.016.

Forster, MD; Moschetta, M; Uccello, M; Kasenda, B; Mak, G; McClelland, A; Boussios, S; Forster, MD; Moschetta, M; Uccello, M; Kasenda, B; Mak, G; McClelland, A; Boussios, S; Arkenau, HT; - view fewer (2017) Dynamics of neutrophils to lymphocyte ratio (NLR) predict outcomes of PD-1/PD-L1 blockade. BioMed Research International , 2017 , Article 1506824. 10.1155/2017/1506824.

Fotopoulou, C; Hall, M; Cruickshank, D; Gabra, H; Ganesan, R; Hughes, C; Kehoe, S; ... Sundar, S; + view all Fotopoulou, C; Hall, M; Cruickshank, D; Gabra, H; Ganesan, R; Hughes, C; Kehoe, S; Ledermann, J; Morrison, J; Naik, R; Rolland, P; Sundar, S; - view fewer (2017) British Gynaecological Cancer Society (BGCS) epithelial ovarian/fallopian tube/primary peritoneal cancer guidelines: recommendations for practice. European Journal of Obstetrics & Gynecology and Reproductive Biology , 213 pp. 123-139. 10.1016/j.ejogrb.2017.04.016.

Foy, V; Schenk, MW; Baker, K; Gomes, F; Lallo, A; Frese, KK; Forster, M; ... Blackhall, F; + view all Foy, V; Schenk, MW; Baker, K; Gomes, F; Lallo, A; Frese, KK; Forster, M; Dive, C; Blackhall, F; - view fewer (2017) Targeting DNA damage in SCLC. [Review]. Lung Cancer , 114 pp. 12-22. 10.1016/j.lungcan.2017.10.006.

Fresneau, B; Hackshaw, A; Hawkins, DS; Paulussen, M; Anderson, JR; Judson, I; Litiere, S; ... Le Teuff, G; + view all Fresneau, B; Hackshaw, A; Hawkins, DS; Paulussen, M; Anderson, JR; Judson, I; Litiere, S; Dirksen, U; Lewis, I; van den Berg, H; Gaspar, N; Gelderblom, H; Whelan, J; Boddy, AV; Wheatley, K; Pignon, JP; De Vathaire, F; Le Deley, MC; Le Teuff, G; - view fewer (2017) Investigating the heterogeneity of alkylating agents' efficacy and toxicity between sexes: A systematic review and meta-analysis of randomized trials comparing cyclophosphamide and ifosfamide (MAIAGE study). Pediatric Blood & Cancer , 64 (8) , Article e26457. 10.1002/pbc.26457.

Furness, CL; Smith, L; Morris, E; Brocklehurst, C; Daly, S; Hough, RE; (2017) Cancer Patient Experience in the Teenage Young Adult Population-Key Issues and Trends Over Time: An Analysis of the United Kingdom National Cancer Patient Experience Surveys 2010-2014. Journal of Adolescent and Young Adult Oncology , 6 (3) pp. 450-458. 10.1089/jayao.2016.0058.

Gale, DP; Molyneux, K; Wimbury, D; Higgins, P; Levine, AP; Caplin, B; Ferlin, A; ... Barratt, J; + view all Gale, DP; Molyneux, K; Wimbury, D; Higgins, P; Levine, AP; Caplin, B; Ferlin, A; Yin, P; Nelson, CP; Stanescu, H; Samani, NJ; Kleta, R; Yu, X; Barratt, J; - view fewer (2017) Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1. J Am Soc Nephrol , 28 (7) pp. 2158-2166. 10.1681/ASN.2016091043.

Galleu, A; Riffo-Vasquez, Y; Trento, C; Lomas, C; Dolcetti, L; Cheung, TS; von Bonin, M; ... Dazzi, F; + view all Galleu, A; Riffo-Vasquez, Y; Trento, C; Lomas, C; Dolcetti, L; Cheung, TS; von Bonin, M; Barbieri, L; Halai, K; Ward, S; Weng, L; Chakraverty, R; Lombardi, G; Watt, FM; Orchard, K; Marks, DI; Apperley, J; Bornhauser, M; Walczak, H; Bennett, C; Dazzi, F; - view fewer (2017) Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation. Science Translational Medicine , 9 (416) , Article eaam7828. 10.1126/scitranslmed.aam7828.

Ganeshan, B; Miles, KA; Babikir, S; Shortman, R; Afaq, A; Ardeshna, KM; Groves, AM; Ganeshan, B; Miles, KA; Babikir, S; Shortman, R; Afaq, A; Ardeshna, KM; Groves, AM; Kayani, I; - view fewer (2017) CT-based texture analysis potentially provides prognostic information complementary to interim fdg-pet for patients with hodgkin's and aggressive non-hodgkin's lymphomas. European Radiology , 27 (3) pp. 1012-1020. 10.1007/s00330-016-4470-8.

Garbowski, MW; Evans, P; Vlachodimitropoulou, E; Hider, R; Porter, JB; (2017) Residual erythropoiesis protects against myocardial hemosiderosis in transfusion-dependent thalassemia by lowering labile plasma iron via transient generation of apotransferrin. Haematologica , 102 pp. 1640-1649. 10.3324/haematol.2017.170605.

Gardiner, C; Kohama, K; Patel, I; Lane, P; Dwyer, S; Machin, SJ; Mackie, IJ; (2017) A performance evaluation of a novel human recombinant tissue factor prothrombin time reagent (Revohem (TM) PT). International Journal of Laboratory Hematology , 39 (5) pp. 532-538. 10.1111/ijlh.12691.

George, A; Kristeleit, R; Rafii, S; Michie, CO; Bowen, R; Michalarea, V; van Hagen, T; ... Yap, TA; + view all George, A; Kristeleit, R; Rafii, S; Michie, CO; Bowen, R; Michalarea, V; van Hagen, T; Wong, M; Rallis, G; Molife, LR; Lopez, J; Banerji, U; Banerjee, SN; Gore, ME; de Bono, JS; Kaye, SB; Yap, TA; - view fewer (2017) Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials. European Journal of Cancer , 76 pp. 52-59. 10.1016/j.ejca.2017.01.020.

Ghorani, E; Kaur, B; Fisher, RA; Short, D; Joneborg, U; Carlson, JW; Akarca, A; ... Seckl, MJ; + view all Ghorani, E; Kaur, B; Fisher, RA; Short, D; Joneborg, U; Carlson, JW; Akarca, A; Marafioti, T; Quezada, SA; Sarwar, N; Seckl, MJ; - view fewer (2017) Pembrolizumab is effective for drugresistant gestational trophoblastic neoplasia. The Lancet , 390 (10110) pp. 2343-2345. 10.1016/S0140-6736(17)32894-5.

Giampazolias, E; Zunino, B; Dhayade, S; Bock, F; Cloix, C; Cao, K; Roca, A; ... Tait, SWG; + view all Giampazolias, E; Zunino, B; Dhayade, S; Bock, F; Cloix, C; Cao, K; Roca, A; Lopez, J; Ichim, G; Proics, E; Rubio-Patino, C; Fort, L; Yatim, N; Woodham, E; Orozco, S; Taraborrelli, L; Peltzer, N; Lecis, D; Machesky, L; Walczak, H; Albert, ML; Milling, S; Oberst, A; Ricci, J-E; Ryan, KM; Blyth, K; Tait, SWG; - view fewer (2017) Mitochondrial permeabilization engages NF-kappa B-dependent anti-tumour activity under caspase deficiency. Nature Cell Biology , 19 (9) pp. 1116-1129. 10.1038/ncb3596.

Gleeson, M; Counsell, N; Cunningham, D; Chadwick, N; Lawrie, A; Hawkes, EA; McMillan, A; ... Linch, D; + view all Gleeson, M; Counsell, N; Cunningham, D; Chadwick, N; Lawrie, A; Hawkes, EA; McMillan, A; Ardeshna, KM; Jack, A; Smith, P; Mouncey, P; Pocock, C; Radford, JA; Davies, J; Turner, D; Kruger, A; Johnson, P; Gambell, J; Linch, D; - view fewer (2017) Central nervous system relapse of diffuse large B-cell lymphoma in the rituximab era: results of the UK NCRI R-CHOP-14 versus 21 trial. Annals of Oncology , 28 (10) pp. 2511-2516. 10.1093/annonc/mdx353.

Glynne-Jones, R; Adams, R; Lopes, A; Meadows, H; (2017) Clinical endpoints in trials of chemoradiation for patients with anal cancer. [Review]. Lancet Oncology , 18 (4) E218-E227. 10.1016/S1470-2045(17)30190-0.

Glynne-Jones, R; Sebag-Montefiore, D; Meadows, HM; Cunningham, D; Begum, R; Adab, F; Benstead, K; ... Kadalayil, L; + view all Glynne-Jones, R; Sebag-Montefiore, D; Meadows, HM; Cunningham, D; Begum, R; Adab, F; Benstead, K; Harte, RJ; Stewart, J; Beare, S; Hackshaw, A; Kadalayil, L; - view fewer (2017) Best time to assess complete clinical response after chemoradiotherapy in squamous cell carcinoma of the anus (ACT II): a post-hoc analysis of randomised controlled phase 3 trial. LANCET ONCOLOGY , 18 (3) pp. 347-356. 10.1016/S1470-2045(17)30071-2.

Godfrey, M; Touati, SA; Kataria, M; Jones, A; Snijders, AP; Uhlmann, F; (2017) PP2A(Cdc55) Phosphatase Imposes Ordered Cell- Cycle Phosphorylation by Opposing Threonine Phosphorylation. Molecular Cell , 65 (3) 393-402.e3. 10.1016/j.molcel.2016.12.018.

Goel, A; Raghupathy, V; Amirtharaj, GJ; Chapla, A; Venkatraman, A; Ramakrishna, B; Ramachandran, A; ... Eapen, CE; + view all Goel, A; Raghupathy, V; Amirtharaj, GJ; Chapla, A; Venkatraman, A; Ramakrishna, B; Ramachandran, A; Thomas, N; Balasubramanian, KA; Mackie, I; Elias, E; Eapen, CE; - view fewer (2017) ADAMTS13 missense variants associated with defective activity and secretion of ADAMTS13 in a patient with non-cirrhotic portal hypertension. Indian Journal of Gastroenterology , 36 (5) pp. 380-389. 10.1007/s12664-017-0786-9.

Gohil, SH; Paredes-Moscosso, SR; Harrasser, M; Vezzalini, M; Scarpa, A; Morris, E; Davidoff, AM; ... Della Peruta, M; + view all Gohil, SH; Paredes-Moscosso, SR; Harrasser, M; Vezzalini, M; Scarpa, A; Morris, E; Davidoff, AM; Sorio, C; Nathwani, AC; Della Peruta, M; - view fewer (2017) An ROR1 bi-specific T-cell engager provides effective targeting and cytotoxicity against a range of solid tumors. OncoImmunology , 6 (7) , Article e1326437. 10.1080/2162402X.2017.1326437.

Gollins, S; West, N; Sebag-Montefiore, D; Myint, AS; Saunders, M; Susnerwala, S; Quirke, P; ... Beare, S; + view all Gollins, S; West, N; Sebag-Montefiore, D; Myint, AS; Saunders, M; Susnerwala, S; Quirke, P; Essapen, S; Samuel, L; Sizer, B; Worlding, J; Southward, K; Hemmings, G; Tinkler-Hundal, E; Taylor, M; Bottomley, D; Chambers, P; Lawrie, E; Lopes, A; Beare, S; - view fewer (2017) Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations. British Journal of Cancer , 117 (9) pp. 1286-1294. 10.1038/bjc.2017.294.

Goodship, THJ; Pinto, F; Weston-Davies, WH; Silva, J; Nishimura, J-I; Nunn, MA; Mackie, I; ... Veys, P; + view all Goodship, THJ; Pinto, F; Weston-Davies, WH; Silva, J; Nishimura, J-I; Nunn, MA; Mackie, I; Machin, SJ; Palm, L; Pryce, JW; Chiesa, R; Amrolia, P; Veys, P; - view fewer (2017) Use of the complement inhibitor Coversin to treat HSCT-associated TMA. Blood Advances , 1 (16) pp. 1254-1258. 10.1182/bloodadvances.2016002832.

Gowers, KHC; Hynds, RE; Thakrar, RM; Carroll, B; Birchall, MA; Janes, SM; (2017) Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples. Journal of Tissue Engineering and Regenerative Medicine 10.1002/term.2466. (In press).

Green, K; Pearce, K; Sellar, RS; Jardine, L; Nicolson, PLR; Nagra, S; Bigley, V; ... Collin, M; + view all Green, K; Pearce, K; Sellar, RS; Jardine, L; Nicolson, PLR; Nagra, S; Bigley, V; Jackson, G; Dickinson, AM; Thomson, K; Mackinnon, S; Craddock, C; Peggs, KS; Collin, M; - view fewer (2017) Impact of Alemtuzumab Scheduling on Graft-versus-Host Disease after Unrelated Donor Fludarabine and Melphalan Allografts. Biology of Blood and Marrow Transplantation , 23 (5) pp. 805-812. 10.1016/j.bbmt.2017.02.007.

Greystoke, A; Steele, N; Arkenau, H-T; Blackhall, F; Haris, NM; Lindsay, CR; Califano, R; ... Dean, E; + view all Greystoke, A; Steele, N; Arkenau, H-T; Blackhall, F; Haris, NM; Lindsay, CR; Califano, R; Voskoboynik, M; Summers, Y; So, K; Ghiorghiu, D; Dymond, AW; Hossack, S; Plummer, R; Dean, E; - view fewer (2017) SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting. British Journal of Cancer , 117 pp. 938-946. 10.1038/bjc.2017.271.

Griffiths, PD; Rothwell, E; Raza, M; Wilmore, S; Doyle, T; Harber, M; O'Beirne, J; ... Emery, VC; + view all Griffiths, PD; Rothwell, E; Raza, M; Wilmore, S; Doyle, T; Harber, M; O'Beirne, J; Mackinnon, S; Jones, G; Thorburn, D; Mattes, F; Nebbia, G; Atabani, S; Smith, C; Stanton, A; Emery, VC; - view fewer (2017) Correction: Randomized Controlled Trials to Define Viral Load Thresholds for Cytomegalovirus Pre-Emptive Therapy. [Corrigendum]. PLOS ONo , 12 (9) , Article e0185298. 10.1371/journal.pone.0185298.

Guibentif, C; Ronn, RE; Boiers, C; Lang, S; Saxena, S; Soneji, S; Enver, T; ... Woods, N-B; + view all Guibentif, C; Ronn, RE; Boiers, C; Lang, S; Saxena, S; Soneji, S; Enver, T; Karlsson, G; Woods, N-B; - view fewer (2017) Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition. Cell Reports , 19 (1) pp. 10-19. 10.1016/j.celrep.2017.03.023.

Gutteridge, A; Rathbone, VM; Gibbons, R; Bi, M; Archard, N; J Davies, KE; Brown, J; ... Forshew, T; + view all Gutteridge, A; Rathbone, VM; Gibbons, R; Bi, M; Archard, N; J Davies, KE; Brown, J; Plagnol, V; Pillay, N; Amary, F; O'Donnell, P; Gupta, M; Tirabosco, R; Flanagan, AM; Forshew, T; - view fewer (2017) Digital PCR analysis of circulating tumor DNA: a biomarker for chondrosarcoma diagnosis, prognostication, and residual disease detection. Cancer Medicine , 6 (10) pp. 2194-2202. 10.1002/cam4.1146.

Hachani, R; Birchall, MA; Lowdell, MW; Kasparis, G; Tung, LD; Manshian, BB; Soenen, SJ; ... Thanh, NTK; + view all Hachani, R; Birchall, MA; Lowdell, MW; Kasparis, G; Tung, LD; Manshian, BB; Soenen, SJ; Gsell, W; Himmelreich, U; Gharagouzloo, CA; Sridhar, S; Thanh, NTK; - view fewer (2017) Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging. Scientific Reports , 7 (1) , Article 7850. 10.1038/s41598-017-08092-w.

Halaska, MJ; Haidopoulos, D; Guyon, F; Morice, P; Zapardiel, I; Kesic, V; Cibula, D; ... Laky, R; + view all Halaska, MJ; Haidopoulos, D; Guyon, F; Morice, P; Zapardiel, I; Kesic, V; Cibula, D; Querleu, D; Gultekin, M; Creutzberg, C; Avall-Lundqvist, E; Goffin, F; Concin, N; Ferrero, A; Kurdiani, D; Ledermann, J; Ponce, J; Sessa, C; Wimberger, P; Marth, C; Laky, R; - view fewer (2017) European Society of Gynecological Oncology Statement on Fibroid and Uterine Morcellation. International Journal of Gynecological Cancer , 27 (1) pp. 189-192. 10.1097/IGC.0000000000000911.

Hall, A; Covelli, C; Manuguerra, R; Luong, TV; Buzzetti, E; Tsochatzis, E; Pinzani, M; Hall, A; Covelli, C; Manuguerra, R; Luong, TV; Buzzetti, E; Tsochatzis, E; Pinzani, M; Dhillon, AP; - view fewer (2017) Transaminase abnormalities and adaptations of the liver lobule manifest at specific cut-offs of steatosis. Sci Rep , 7 , Article 40977. 10.1038/srep40977.

Harrington, K; Hall, E; Hawkins, M; Henry, A; MacKay, R; Maughan, T; McDonald, A; ... Faivre-Finn, C; + view all Harrington, K; Hall, E; Hawkins, M; Henry, A; MacKay, R; Maughan, T; McDonald, A; Nutting, C; Oelfke, U; Sebag-Montefiore, D; Sharma, RA; van Herk, M; Faivre-Finn, C; - view fewer (2017) Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET). Clinical Oncology , 29 (11) pp. 707-710. 10.1016/j.clon.2017.07.016.

Hartwig, T; Montinaro, A; von Karstedt, S; Sevko, A; Surinova, S; Chakravarthy, A; Taraborrelli, L; ... Walczak, H; + view all Hartwig, T; Montinaro, A; von Karstedt, S; Sevko, A; Surinova, S; Chakravarthy, A; Taraborrelli, L; Draber, P; Lafont, E; Arce Vargas, F; El-Bahrawy, MA; Quezada, SA; Walczak, H; - view fewer (2017) The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2. Molecular Cell , 65 (4) pp. 730-742. 10.1016/j.molcel.2017.01.021.

Heather, JM; Ismail, M; Oakes, T; Chain, B; (2017) High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities. Brief Bioinform 10.1093/bib/bbw138. (In press).

Helfen, A; Roth, J; Ng, T; Eisenblaetter, M; (2017) In Vivo Imaging of Pro- and Antitumoral Cellular Components of the Tumor Microenvironment. Journal of Nuclear Medicine , 59 (2) pp. 183-188. 10.2967/jnumed.117.198952.

Hirst, Y; Skrobanski, H; Kerrison, RS; Kobayashi, LC; Counsell, N; Djedovic, N; Ruwende, J; ... von Wagner, C; + view all Hirst, Y; Skrobanski, H; Kerrison, RS; Kobayashi, LC; Counsell, N; Djedovic, N; Ruwende, J; Stewart, M; von Wagner, C; - view fewer (2017) Text-message Reminders in Colorectal Cancer Screening (TRICCS): a randomised controlled trial. British Journal of Cancer , 116 pp. 1408-1414. 10.1038/bjc.2017.117.

Hough, R; Sandhu, S; Khan, M; Moran, A; Feltbower, R; Stiller, C; Stevens, MCG; ... McCabe, MG; + view all Hough, R; Sandhu, S; Khan, M; Moran, A; Feltbower, R; Stiller, C; Stevens, MCG; Rowntree, C; Vora, A; McCabe, MG; - view fewer (2017) Are survival and mortality rates associated with recruitment to clinical trials in teenage and young adult patients with acute lymphoblastic leukaemia? A retrospective observational analysis in England. BMJ Open , 7 (10) , Article e017052. 10.1136/bmjopen-2017-017052.

Hsieh, JJ; Purdue, MP; Signoretti, S; Swanton, C; Albiges, L; Schmidinger, M; Heng, DY; ... Ficarra, V; + view all Hsieh, JJ; Purdue, MP; Signoretti, S; Swanton, C; Albiges, L; Schmidinger, M; Heng, DY; Larkin, J; Ficarra, V; - view fewer (2017) Renal cell carcinoma. Nature Reviews Disease Primers , 3 , Article 17009. 10.1038/nrdp.2017.9.

Hughes, D; Giugliani, R; Guffon, N; Jones, SA; Mengel, KE; Parini, R; Matousek, R; ... Quartel, A; + view all Hughes, D; Giugliani, R; Guffon, N; Jones, SA; Mengel, KE; Parini, R; Matousek, R; Hawley, SM; Quartel, A; - view fewer (2017) Clinical outcomes in a subpopulation of adults with Morquio A syndrome: results from a long-term extension study of elosulfase alfa. Orphanet Journal of Rare Diseases , 12 , Article 98. 10.1186/s13023-017-0634-0.

Hughes, DA; Nicholls, K; Shankar, SP; Sunder-Plassmann, G; Koeller, D; Nedd, K; Vockley, G; ... Feldt-Rasmussen, U; + view all Hughes, DA; Nicholls, K; Shankar, SP; Sunder-Plassmann, G; Koeller, D; Nedd, K; Vockley, G; Hamazaki, T; Lachmann, R; Ohashi, T; Olivotto, I; Sakai, N; Deegan, P; Dimmock, D; Eyskens, F; Germain, DP; Goker-Alpan, O; Hachulla, E; Jovanovic, A; Lourenco, CM; Narita, I; Thomas, M; Wilcox, WR; Bichet, DG; Schiffmann, R; Ludington, E; Viereck, C; Kirk, J; Yu, J; Johnson, F; Boudes, P; Benjamin, ER; Lockhart, DJ; Barlow, C; Skuban, N; Castelli, JP; Barth, J; Feldt-Rasmussen, U; - view fewer (2017) Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study. Journal of Medical Genetics , 54 (4) pp. 288-296. 10.1136/jmedgenet-2016-104178.

Hynds, RE; Bonfanti, P; Janes, SM; (2017) Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond. EMBO Molecular Medicine , 2017 , Article e8213. 10.15252/emmm.201708213.

Hynds, RE; Janes, SM; (2017) Airway Basal Cell Heterogeneity and Lung Squamous Cell Carcinoma. Cancer Prevention Research , 10 (9) pp. 491-493. 10.1158/1940-6207.CAPR-17-0202.

Irshad, S; Flores-Borja, F; Lawler, K; Monypenny, J; Evans, R; Male, V; Gordon, P; ... Ng, T; + view all Irshad, S; Flores-Borja, F; Lawler, K; Monypenny, J; Evans, R; Male, V; Gordon, P; Cheung, A; Gazinska, P; Noor, F; Wong, F; Grigoriadis, A; Fruhwirth, G; Barber, PR; Woodman, N; Patel, D; Rodriguez-Justo, M; Owen, J; Martin, SG; Pinder, S; Gillett, C; Poland, SP; Ameer-Beg, S; Mccaughan, F; Carlin, L; Hasan, U; Withers, DR; Lane, P; Vojnovic, B; Quezada, SA; Ellis, P; Tutt, AN; Ng, T; - view fewer (2017) RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers. Cancer Research , 77 (5) pp. 1083-1096. 10.1158/0008-5472.CAN-16-0598.

Islam, MS; Saito, JA; Emdad, EM; Ahmed, B; Islam, MM; Halim, A; Hossen, QMM; ... Alam, M; + view all Islam, MS; Saito, JA; Emdad, EM; Ahmed, B; Islam, MM; Halim, A; Hossen, QMM; Hossain, MZ; Ahmed, R; Hossain, MS; Kabir, SMT; Khan, MSA; Khan, MM; Hasan, R; Aktar, N; Honi, U; Islam, R; Rashid, MM; Wan, X; Hou, S; Haque, T; Azam, MS; Moosa, MM; Elias, SM; Hasan, AMM; Mahmood, N; Shafiuddin, M; Shahid, S; Shommu, NS; Jahan, S; Roy, S; Chowdhury, A; Akhand, AI; Nisho, GM; Uddin, KS; Rabeya, T; Hoque, SME; Snigdha, AR; Mortoza, S; Matin, SA; Islam, MK; Lashkar, MZH; Zaman, M; Yuryev, A; Uddin, MK; Rahman, MS; Haque, MS; Alam, MM; Khan, H; Alam, M; - view fewer (2017) Comparative genomics of two jute species and insight into fibre biogenesis. Nature Plants , 3 (2) , Article 16223. 10.1038/nplants.2016.223.

Jackson, LH; Vlachodimitropoulou, E; Shangaris, P; Roberts, TA; Ryan, TM; Campbell-Washburn, AE; David, AL; ... Stuckey, DJ; + view all Jackson, LH; Vlachodimitropoulou, E; Shangaris, P; Roberts, TA; Ryan, TM; Campbell-Washburn, AE; David, AL; Porter, JB; Lythgoe, MF; Stuckey, DJ; - view fewer (2017) Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia. Scientific Reports , 7 , Article 43439. 10.1038/srep43439.

Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; ... Swanton, C; + view all Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; Johnson, DH; Mitter, R; Rosenthal, R; Salm, M; Horswell, S; Escudero, M; Matthews, N; Rowan, A; Chambers, T; Moore, DA; Turajlic, S; Xu, H; Lee, S-M; Forster, MD; Ahmad, T; Hiley, CT; Abbosh, C; Falzon, M; Borg, E; Marafioti, T; Lawrence, D; Hayward, M; Kolvekar, S; Panagiotopoulos, N; Janes, SM; Thakrar, R; Ahmed, A; Blackhall, F; Summers, Y; Shah, R; Joseph, L; Quinn, AM; Crosbie, PA; Naidu, B; Middleton, G; Langman, G; Trotter, S; Nicolson, M; Remmen, H; Kerr, K; Chetty, M; Gomersall, L; Fennell, DA; Nakas, A; Rathinam, S; Anand, G; Khan, S; Russell, P; Ezhil, V; Ismail, B; Irvin-Sellers, M; Prakash, V; Lester, JF; Kornaszewska, M; Attanoos, R; Adams, H; Davies, H; Dentro, S; Taniere, P; O'Sullivan, B; Lowe, HL; Hartley, JA; Iles, N; Bell, H; Ngai, Y; Shaw, JA; Herrero, J; Szallasi, Z; Schwarz, RF; Stewart, A; Quezada, SA; Le Quesne, J; Van Loo, P; Dive, C; Hackshaw, A; Swanton, C; - view fewer (2017) Tracking the Evolution of Non-Small-Cell Lung Cancer. New England Journal of Medicine , 376 (22) pp. 2109-2121. 10.1056/NEJMoa1616288.

James, ND; de Bono, JS; Spears, MR; Clarke, NW; Mason, MD; Dearnaley, DP; Ritchie, AWS; ... STAMPEDE Investigators; + view all James, ND; de Bono, JS; Spears, MR; Clarke, NW; Mason, MD; Dearnaley, DP; Ritchie, AWS; Amos, CL; Gilson, C; Jones, RJ; Matheson, D; Millman, R; Attard, G; Chowdhury, S; Cross, WR; Gillessen, S; Parker, CC; Russell, JM; Berthold, DR; Brawley, C; Adab, F; Aung, S; Birtle, AJ; Bowen, J; Brock, S; Chakraborti, P; Ferguson, C; Gale, J; Gray, E; Hingorani, M; Hoskin, PJ; Lester, JF; Malik, ZI; McKinna, F; McPhail, N; Money-Kyrle, J; O'Sullivan, J; Parikh, O; Protheroe, A; Robinson, A; Srihari, NN; Thomas, C; Wagstaff, J; Wylie, J; Zarkar, A; Parmar, MKB; Sydes, MR; STAMPEDE Investigators; - view fewer (2017) Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy. The New England Journal of Medicine , 377 pp. 338-351. 10.1056/NEJMoa1702900.

Janczar, S; Janczar, K; Pastorczak, A; Harb, H; Paige, AJW; Zalewska-Szewczyk, B; Danilewicz, M; Janczar, S; Janczar, K; Pastorczak, A; Harb, H; Paige, AJW; Zalewska-Szewczyk, B; Danilewicz, M; Mlynarski, W; - view fewer (2017) The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia. [Review]. Cancers , 9 (1) , Article 2. 10.3390/cancers9010002.

Janczar, S; Nautiyal, J; Xiao, Y; Curry, E; Sun, M; Zanini, E; Paige, AJ; Janczar, S; Nautiyal, J; Xiao, Y; Curry, E; Sun, M; Zanini, E; Paige, AJ; Gabra, H; - view fewer (2017) WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response. Cell Death and Disease , 8 , Article e2955. 10.1038/cddis.2017.346.

Jang, JYA; Yanaihara, N; Pujade-Lauraine, E; Mikami, Y; Oda, K; Bookman, M; Ledermann, J; ... Okamoto, A; + view all Jang, JYA; Yanaihara, N; Pujade-Lauraine, E; Mikami, Y; Oda, K; Bookman, M; Ledermann, J; Shimada, M; Kiyokawa, T; Kim, BG; Matsumura, N; Kaku, T; Kuroda, T; Nagayoshi, Y; Kawabata, A; Iida, Y; Kim, JW; Quinn, M; Okamoto, A; - view fewer (2017) Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference. Journal of Gynecologic Oncology , 28 (4) , Article e54. 10.3802/jgo.2017.28.e54.

Jones, OS; Vassie, C; Gilson, R; Lechner, M; (2017) Until eradication, awareness. Lancet Infectious Diseases , 17 (4) pp. 368-369. 10.1016/S1473-3099(17)30125-1.

Josephs, DH; Bax, HJ; Dodev, T; Georgouli, M; Nakamura, M; Pellizzari, G; Saul, L; ... Karagiannis, SN; + view all Josephs, DH; Bax, HJ; Dodev, T; Georgouli, M; Nakamura, M; Pellizzari, G; Saul, L; Karagiannis, P; Cheung, A; Herraiz, C; Ilieva, KM; Correa, I; Fittall, M; Crescioli, S; Gazinska, P; Woodman, N; Mele, S; Chiaruttini, G; Gilbert, AE; Koers, A; Bracher, M; Selkirk, C; Lentfer, H; Barton, C; Lever, E; Muirhead, G; Tsoka, S; Canevari, S; Figini, M; Montes, A; Downes, N; Dombrowicz, D; Corrigan, CJ; Beavil, AJ; Nestle, FO; Jones, PS; Gould, HJ; Sanz-Moreno, V; Blower, PJ; Spicer, JF; Karagiannis, SN; - view fewer (2017) Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling. Cancer Research , 77 (5) pp. 1127-1141. 10.1158/0008-5472.CAN-16-1829.

Joshi, K; Chain, BM; Peggs, KS; Quezada, SA; (2017) The "Achilles Heel" of Cancer and Its Implications for the Development of Novel Immunotherapeutic Strategies. Cold Spring Harbor Perspectives in Medicine 10.1101/cshperspect.a027086. (In press).

Kantarjian, H; Stein, A; Goekbuget, N; Fielding, AK; Schuh, AC; Ribera, J-M; Wei, A; ... Topp, MS; + view all Kantarjian, H; Stein, A; Goekbuget, N; Fielding, AK; Schuh, AC; Ribera, J-M; Wei, A; Dombret, H; Foa, R; Bassan, R; Arslan, O; Sanz, MA; Bergeron, J; Demirkan, F; Lech-Maranda, E; Rambaldi, A; Thomas, X; Horst, H-A; Brueggemann, M; Klapper, W; Wood, BL; Fleishman, A; Nagorsen, D; Holland, C; Zimmerman, Z; Topp, MS; - view fewer (2017) Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia. New England Journal of Medicine , 376 (9) pp. 836-847. 10.1056/NEJMoa1609783.

Karam, A; Ledermann, JA; Kim, J-W; Sehouli, J; Lu, K; Gourley, C; Katsumata, N; ... Ochiai, K; + view all Karam, A; Ledermann, JA; Kim, J-W; Sehouli, J; Lu, K; Gourley, C; Katsumata, N; Burger, RA; Nam, B-H; Bacon, M; Ng, C; Pfisterer, J; Bekkers, RLM; Casado Herraez, A; Redondo, A; Fujiwara, H; Gleeson, N; Rosengarten, O; Scambia, G; Zhu, J; Okamoto, A; Stuart, G; Ochiai, K; - view fewer (2017) Fifth Ovarian Cancer Consensus Conference of the Gynecologic Cancer InterGroup: first-line interventions. Annals of Oncology , 28 (4) pp. 711-717. 10.1093/annonc/mdx011.

Karpathakis, A; Dibra, H; Pipinikas, C; Feber, A; Morris, T; Francis, JM; Oukrif, D; ... Thirlwell, C; + view all Karpathakis, A; Dibra, H; Pipinikas, C; Feber, A; Morris, T; Francis, JM; Oukrif, D; Mandair, D; Pericleous, M; Mohmaduvesh, M; Serra, S; Ogunbiyi, O; Novelli, M; Luong, TV; Asa, SL; Kulke, MH; Toumpanakis, C; Meyer, T; Caplin, M; Beck, S; Thirlwell, C; - view fewer (2017) Progressive epigenetic dysregulation in neuroendocrine tumour liver metastasis. Endocrine-Related Cancer , 24 (2) L21-L25. 10.1530/ERC-16-0419.

Kato, I; Nishinaka, Y; Nakamura, M; Akarca, AU; Niwa, A; Ozawa, H; Yoshida, K; ... Enver, T; + view all Kato, I; Nishinaka, Y; Nakamura, M; Akarca, AU; Niwa, A; Ozawa, H; Yoshida, K; Mori, M; Wang, D; Morita, M; Ueno, H; Shiozawa, Y; Shiraishi, Y; Miyano, S; Gupta, R; Umeda, K; Watanabe, K; Koh, K; Adachi, S; Heike, T; Saito, MK; Sanada, M; Ogawa, S; Marafioti, T; Watanabe, A; Nakahata, T; Enver, T; - view fewer (2017) Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA. Blood , 129 (23) pp. 3126-3129. 10.1182/blood-2016-06-721712.

Kayhanian, H; Smyth, EC; Braconi, C; (2017) Emerging molecular targets and therapy for cholangiocarcinoma. [Review]. World Journal of Gastrointestinal Oncology , 9 (7) pp. 268-280. 10.4251/wjgo.v9.i7.268.

Keller, DS; Joshi, HM; Rodriguez-Justo, M; Walsh, D; Coffey, JC; Chand, M; (2017) Using fluorescence lymphangiography to define the ileocolic mesentery: proof of concept for the watershed area using real-time imaging. Techniques in Coloproctology , 21 (9) pp. 757-760. 10.1007/s10151-017-1677-x.

Kennedy, A; Brown, DB; Feilchenfeldt, J; Marshall, J; Wasan, H; Fakih, M; Gibbs, P; ... Sharma, RA; + view all Kennedy, A; Brown, DB; Feilchenfeldt, J; Marshall, J; Wasan, H; Fakih, M; Gibbs, P; Knuth, A; Sangro, B; Soulen, MC; Pittari, G; Sharma, RA; - view fewer (2017) Safety of selective internal radiation therapy (SIRT) with yttrium-90 microspheres combined with systemic anticancer agents: expert consensus. Journal of Gastrointestinal Oncology , 8 (6) pp. 1079-1099. 10.21037/jgo.2017.09.10.

Kenten, C; Martins, A; Fern, LA; Gibson, F; Lea, S; Ngwenya, N; Whelan, JS; Kenten, C; Martins, A; Fern, LA; Gibson, F; Lea, S; Ngwenya, N; Whelan, JS; Taylor, RM; - view fewer (2017) Qualitative study to understand the barriers to recruiting young people with cancer to BRIGHTLIGHT: a national cohort study in England. BMJ Open , 7 (11) , Article e018291. 10.1136/bmjopen-2017-018291.

Kerrison, RS; McGregor, LM; Marshall, S; Isitt, J; Counsell, N; Rees, CJ; von Wagner, C; (2017) Improving uptake of flexible sigmoidoscopy screening: a randomized trial of nonparticipant reminders in the English Screening Programme. Endoscopy , 49 (1) pp. 35-43. 10.1055/s-0042-118452.

King, J; Palmer, DH; Johnson, P; Ross, P; Hubner, RA; Sumpter, K; Darby, S; ... Meyer, T; + view all King, J; Palmer, DH; Johnson, P; Ross, P; Hubner, RA; Sumpter, K; Darby, S; Braconi, C; Iwuji, C; Swinson, D; Collins, P; Patel, K; Nobes, J; Muazzam, I; Blesing, C; Kirkwood, A; Nash, S; Meyer, T; - view fewer (2017) Sorafenib for the Treatment of Advanced Hepatocellular Cancer – a UK Audit. Clinical Oncology , 29 (4) pp. 256-262. 10.1016/j.clon.2016.11.012.

Kirk, P; Sheppard, M; Carpenter, J-P; Anderson, L; He, T; St Pierre, T; Galanello, R; ... Pennell, DJ; + view all Kirk, P; Sheppard, M; Carpenter, J-P; Anderson, L; He, T; St Pierre, T; Galanello, R; Catani, G; Wood, J; Fucharoen, S; Porter, JB; Walker, JM; Forni, GL; Pennell, DJ; - view fewer (2017) Post-mortem study of the association between cardiac iron and fibrosis in transfusion dependent anaemia. Journal of Cardiovascular Magnetic Resonance , 19 (1) , Article 36. 10.1186/s12968-017-0349-3.

Kling, T; Wenger, A; Beck, S; Caren, H; (2017) Validation of the Methylation EPIC BeadChip for fresh-frozen and formalin-fixed paraffinembedded tumours. Clinical Epigenetics , 9 , Article 33. 10.1186/s13148-017-0333-7.

Knapper, S; Russell, N; Gilkes, A; Hills, RK; Gale, RE; Cavenagh, JD; Jones, G; ... Burnett, AK; + view all Knapper, S; Russell, N; Gilkes, A; Hills, RK; Gale, RE; Cavenagh, JD; Jones, G; Kjeldsen, L; Grunwald, MR; Thomas, I; Konig, H; Levis, MJ; Burnett, AK; - view fewer (2017) A randomised assessment of adding the kinase inhibitor lestaurtinib to 1st-line chemotherapy for FLT3-mutated AML. Blood , 129 (9) pp. 1143-1154. 10.1182/blood-2016-07-730648.

Knight, AE; Gomez, K; Cutler, DF; (2017) Super-resolution microscopy in the diagnosis of platelet granule disorders. Expert Review of Hematology , 10 (5) pp. 375-381. 10.1080/17474086.2017.1315302.

Kozor, R; Nordin, S; Treibel, TA; Rosmini, S; Castelletti, S; Fontana, M; Captur, G; ... Moon, JC; + view all Kozor, R; Nordin, S; Treibel, TA; Rosmini, S; Castelletti, S; Fontana, M; Captur, G; Baig, S; Steeds, RP; Hughes, D; Manisty, C; Grieve, SM; Figtree, GA; Moon, JC; - view fewer (2017) Insight into hypertrophied hearts: a cardiovascular magnetic resonance study of papillary muscle mass and T1 mapping. European Heart Journal - Cardiovascular Imaging , 18 (9) pp. 1034-1040. 10.1093/ehjci/jew187.

Kristeleit, R; Davidenko, I; Shirinkin, V; El-Khouly, F; Bondarenko, I; Goodheart, MJ; Gorbunova, V; ... Schilder, RJ; + view all Kristeleit, R; Davidenko, I; Shirinkin, V; El-Khouly, F; Bondarenko, I; Goodheart, MJ; Gorbunova, V; Penning, CA; Shi, JG; Liu, X; Newton, RC; Zhao, Y; Maleski, J; Leopold, L; Schilder, RJ; - view fewer (2017) A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)-only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer. Gynecologic Oncology , 146 (3) pp. 484-490. 10.1016/j.ygyno.2017.07.005.

Kristeleit, R; Shapiro, GI; Burris, HA; Oza, AM; LoRusso, P; Patel, MR; Domchek, SM; ... Shapira-Frommer, R; + view all Kristeleit, R; Shapiro, GI; Burris, HA; Oza, AM; LoRusso, P; Patel, MR; Domchek, SM; Balmana, J; Drew, Y; Chen, L-M; Safra, T; Montes, A; Giordano, H; Maloney, L; Goble, S; Isaacson, J; Xiao, J; Borrow, J; Rolfe, L; Shapira-Frommer, R; - view fewer (2017) A Phase I-II Study of the Oral PARP Inhibitor Rucaparib in Patients with Germline BRCA1/2-Mutated Ovarian Carcinoma or Other Solid Tumors. Clinical Cancer Research , 23 (15) pp. 4095-4106. 10.1158/1078-0432.CCR-16-2796.

Kuderna, LFK; Tomlinson, C; Hillier, LW; Tran, A; Fiddes, I; Armstrong, J; Laayouni, H; ... Marques-Bonet, T; + view all Kuderna, LFK; Tomlinson, C; Hillier, LW; Tran, A; Fiddes, I; Armstrong, J; Laayouni, H; Gordon, D; Huddleston, J; Perez, RG; Povolotskaya, I; Armero, AS; Garrido, JG; Ho, D; Ribeca, P; Alioto, T; Green, RE; Paten, B; Navarro, A; Betranpetit, J; Herrero, J; Eichler, EE; Sharp, AJ; Feuk, L; Warren, WC; Marques-Bonet, T; - view fewer (2017) A 3-way hybrid approach to generate a new high quality chimpanzee reference genome (Pan_tro_3.0). GigaScience , 6 (11) pp. 1-6. 10.1093/gigascience/gix098.

Kühnl, A; Cunningham, D; Counsell, N; Hawkes, EA; Qian, W; Smith, P; Chadwick, N; ... Linch, D; + view all Kühnl, A; Cunningham, D; Counsell, N; Hawkes, EA; Qian, W; Smith, P; Chadwick, N; Lawrie, A; Mouncey, P; Jack, A; Pocock, C; Ardeshna, KM; Radford, J; McMillan, A; Davies, J; Turner, D; Kruger, A; Johnson, P; Gambell, J; Rosenwald, A; Ott, G; Horn, H; Ziepert, M; Pfreundschuh, M; Linch, D; - view fewer (2017) Outcome of Elderly Patients with Diffuse Large B-cell Lymphoma Treated with R-CHOP: Results from the UK NCRI R-CHOP14v21 trial with combined analysis of molecular characteristics with the DSHNHL RICOVER-60 trial. Annals of Oncology , 28 (7) pp. 1540-1546. 10.1093/annonc/mdx128.

La Paglia, L; Listi, A; Caruso, S; Amodeo, V; Passiglia, F; Bazan, V; Fanale, D; (2017) Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway. PPAR Research , 2017 , Article 8187235. 10.1155/2017/8187235.

Labib, PLZ; Davidson, B; Sharma, RA; Pereira, SP; (2017) Locoregional therapies in cholangiocarcinoma. Hepatic Oncology , 4 (4) pp. 99-109. 10.2217/hep-2017-0014.

Lafont, E; Kantari-Mimoun, C; Draber, P; De Miguel, D; Hartwig, T; Reichert, M; Kupka, S; ... Walczak, H; + view all Lafont, E; Kantari-Mimoun, C; Draber, P; De Miguel, D; Hartwig, T; Reichert, M; Kupka, S; Shimizu, Y; Taraborrelli, L; Spit, M; Sprick, MR; Walczak, H; - view fewer (2017) The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO Journal , 36 (6) , Article e201695699. 10.15252/embj.201695699.

Lamarca, A; Walter, T; Pavel, M; Borbath, I; Freis, P; Nuñez, B; Childs, A; ... Barriuso, J; + view all Lamarca, A; Walter, T; Pavel, M; Borbath, I; Freis, P; Nuñez, B; Childs, A; McNamara, MG; Hubner, RA; Garcia-Carbonero, R; Meyer, T; Valle, JW; Barriuso, J; - view fewer (2017) Design and Validation of the GI-NEC Score to Prognosticate Overall Survival in Patients With High-Grade Gastrointestinal Neuroendocrine Carcinomas. Journal of the National Cancer Institute , 109 (5) 10.1093/jnci/djw277.

Lampada, A; O'Prey, J; Szabadkai, G; Ryan, KM; Hochhauser, D; Salomoni, P; (2017) mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism. Cell Death and Differentiation , 24 (6) pp. 1045-1062. 10.1038/cdd.2017.41.

Lanceley, A; Berzuini, C; Burnell, M; Gessler, S; Morris, S; Ryan, A; Ledermann, JA; Lanceley, A; Berzuini, C; Burnell, M; Gessler, S; Morris, S; Ryan, A; Ledermann, JA; Jacobs, I; - view fewer (2017) Ovarian Cancer Follow-up: A Preliminary Comparison of 2 Approaches. International Journal of Gynecological Cancer , 27 (1) pp. 59-68. 10.1097/IGC.0000000000000877.

Laskaratos, F-M; Rombouts, K; Caplin, M; Toumpanakis, C; Thirlwell, C; Mandair, D; (2017) Neuroendocrine tumors and fibrosis: An unsolved mystery? Cancer , 123 (24) pp. 4770-4790. 10.1002/cncr.31079.

Latifoltojar, A; Hall-Craggs, M; Bainbridge, A; Rabin, N; Popat, R; Rismani, A; D'Sa, S; ... Punwani, S; + view all Latifoltojar, A; Hall-Craggs, M; Bainbridge, A; Rabin, N; Popat, R; Rismani, A; D'Sa, S; Dikaios, N; Sokolska, M; Antonelli, M; Ourselin, S; Yong, K; Taylor, SA; Halligan, S; Punwani, S; - view fewer (2017) Whole-body MRI quantitative biomarkers are associated significantly with treatment response in patients with newly diagnosed symptomatic multiple myeloma following bortezomib induction. European Radiology 10.1007/s00330-017-4907-8. (In press).

Latifoltojar, A; Hall-Craggs, M; Rabin, N; Popat, R; Bainbridge, A; Dikaios, N; Sokolska, M; ... Yong, K; + view all Latifoltojar, A; Hall-Craggs, M; Rabin, N; Popat, R; Bainbridge, A; Dikaios, N; Sokolska, M; Rismani, A; D'Sa, S; Punwani, S; Yong, K; - view fewer (2017) Whole body magnetic resonance imaging in newly diagnosed multiple myeloma: early changes in lesional signal fat fraction predict disease response. British Journal of Haematology , 176 (2) pp. 222-233. 10.1111/bjh.14401.

Law, PJ; Berndt, SI; Speedy, HE; Camp, NJ; Sava, GP; Skibola, CF; Holroyd, A; ... Slager, S; + view all Law, PJ; Berndt, SI; Speedy, HE; Camp, NJ; Sava, GP; Skibola, CF; Holroyd, A; Joseph, V; Sunter, NJ; Nieters, A; Bea, S; Monnereau, A; Martin-Garcia, D; Goldin, LR; Clot, G; Teras, LR; Quintela, I; Birmann, BM; Jayne, S; Cozen, W; Majid, A; Smedby, KE; Lan, Q; Dearden, C; Brooks-Wilson, AR; Hall, AG; Purdue, MP; Mainou-Fowler, T; Vajdic, CM; Jackson, GH; Cocco, P; Marr, H; Zhang, Y; Zheng, T; Giles, GG; Lawrence, C; Call, TG; Liebow, M; Melbye, M; Glimelius, B; Mansouri, L; Glenn, M; Curtin, K; Diver, WR; Link, BK; Conde, L; Bracci, PM; Holly, EA; Jackson, RD; Tinker, LF; Benavente, Y; Boffetta, P; Brennan, P; Maynadie, M; McKay, J; Albanes, D; Weinstein, S; Wang, Z; Caporaso, NE; Morton, LM; Severson, RK; Riboli, E; Vineis, P; Vermeulen, RC; Southey, MC; Milne, RL; Clavel, J; Topka, S; Spinelli, JJ; Kraft, P; Ennas, MG; Summerfield, G; Ferri, GM; Harris, RJ; Miligi, L; Pettitt, AR; North, KE; Allsup, DJ; Fraumeni, JF; Bailey, JR; Offit, K; Pratt, G; Hjalgrim, H; Pepper, C; Chanock, SJ; Fegan, C; Rosenquist, R; de Sanjose, S; Carracedo, A; Dyer, MJ; Catovsky, D; Campo, E; Cerhan, JR; Allan, JM; Rothman, N; Houlston, R; Slager, S; - view fewer (2017) Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. Nature Communications , 8 , Article 14175. 10.1038/ncomms14175.

Lawler, K; Papouli, E; Naceur-Lombardelli, C; Mera, A; Ougham, K; Tutt, A; Kimbung, S; ... Purushotham, A; + view all Lawler, K; Papouli, E; Naceur-Lombardelli, C; Mera, A; Ougham, K; Tutt, A; Kimbung, S; Hedenfalk, I; Zhan, J; Zhang, H; Buus, R; Dowsett, M; Ng, T; Pinder, SE; Parker, P; Holmberg, L; Gillett, CE; Grigoriadis, A; Purushotham, A; - view fewer (2017) Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study. Breast Cancer Research , 19 , Article 113. 10.1186/s13058-017-0881-y.

Ledermann, JA; (2017) Front-line therapy of advanced ovarian cancer: new approaches. Annals of Oncology , 28 (Suppl. 8) viii46-viii50. 10.1093/annonc/mdx452.

Lee, E; Milan, A; Urbani, L; De Coppi, P; Lowdell, MW; (2017) Decellularized material as scaffolds for tissue engineering studies in long gap esophageal atresia. Expert Opinion on Biological Therapy , 17 (5) pp. 573-584. 10.1080/14712598.2017.1308482.

Lee, KCL; Baker, L; Mallett, S; Riddell, A; Chowdary, P; Alibhai, H; Chang, Y-M; ... Agarwal, B; + view all Lee, KCL; Baker, L; Mallett, S; Riddell, A; Chowdary, P; Alibhai, H; Chang, Y-M; Priestnall, S; Stanzani, G; Davies, N; Mookerjee, R; Jalan, R; Agarwal, B; - view fewer (2017) Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. Scientific Reports , 7 (1) , Article 9347. 10.1038/s41598-017-09508-3.

Lee, L; Draper, B; Chaplin, N; Philip, B; Chin, M; Galas-Filipowicz, D; Onuoha, S; ... Pule, M; + view all Lee, L; Draper, B; Chaplin, N; Philip, B; Chin, M; Galas-Filipowicz, D; Onuoha, S; Thomas, S; Baldan, V; Bughda, R; Maciocia, P; Kokalaki, E; Neves, MP; Patel, D; Rodriguez-Justo, M; Francis, J; Yong, K; Pule, M; - view fewer (2017) An APRIL based chimeric antigen receptor for dual targeting of BCMA and TACI in Multiple Myeloma. Blood , 2017 (5) , Article 781351. 10.1182/blood-2017-05-781351.

Lewis, AT; Gaifulina, R; Isabelle, M; Dorney, J; Woods, ML; Lloyd, GR; Lau, K; ... Thomas, GM; + view all Lewis, AT; Gaifulina, R; Isabelle, M; Dorney, J; Woods, ML; Lloyd, GR; Lau, K; Rodriguez-Justo, M; Kendall, C; Stone, N; Thomas, GM; - view fewer (2017) Mirrored stainless steel substrate provides improved signal for Raman spectroscopy of tissue and cells. Journal of Raman Spectroscopy , 48 (1) pp. 119-125. 10.1002/jrs.4980.

Lheureux, S; Lai, Z; Dougherty, BA; Runswick, S; Hodgson, DR; Timms, KM; Lanchbury, JS; ... Oza, AM; + view all Lheureux, S; Lai, Z; Dougherty, BA; Runswick, S; Hodgson, DR; Timms, KM; Lanchbury, JS; Kaye, S; Gourley, C; Bowtell, D; Kohn, EC; Scott, C; Matulonis, U; Panzarella, T; Karakasis, K; Burnier, JV; Gilks, CB; O'Connor, MJ; Robertson, JD; Ledermann, J; Barrett, JC; Ho, TW; Oza, AM; - view fewer (2017) Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization. Clinical Cancer Research , 23 (15) pp. 4086-4094. 10.1158/1078-0432.CCR-16-2615.

Li, Z; Abraham, BJ; Berezovskaya, A; Farah, N; Liu, Y; Leon, T; Fielding, A; ... Look, AT; + view all Li, Z; Abraham, BJ; Berezovskaya, A; Farah, N; Liu, Y; Leon, T; Fielding, A; Tan, SH; Sanda, T; Weintraub, AS; Li, B; Shen, S; Zhang, J; Mansour, MR; Young, RA; Look, AT; - view fewer (2017) APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL. Leukemia 10.1038/leu.2017.75.

Lim, EL; Trinh, DL; Ries, RE; Wang, J; Gerbing, RB; Ma, Y; Topham, J; ... Marra, MA; + view all Lim, EL; Trinh, DL; Ries, RE; Wang, J; Gerbing, RB; Ma, Y; Topham, J; Hughes, M; Pleasance, E; Mungall, AJ; Moore, R; Zhao, Y; Aplenc, R; Sung, L; Kolb, EA; Gamis, A; Smith, M; Gerhard, DS; Alonzo, TA; Meshinchi, S; Marra, MA; - view fewer (2017) MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia. Journal of Clinical Oncology , 35 (35) pp. 3964-3977. 10.1200/JCO.2017.74.7451.

Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, YNS; ... Swanton, C; + view all Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, YNS; King, H; Furness, A; Freeman, A; Linares, J; Akarca, A; Herrero, J; Rosenthal, R; Harder, N; Schmidt, G; Wilson, GA; Birkbak, NJ; Mitter, R; Dentro, S; Cathcart, P; Arya, M; Johnston, E; Scott, R; Hung, M; Emberton, M; Attard, G; Szallasi, Z; Punwani, S; Quezada, SA; Marafioti, T; Gerlinger, M; Ahmed, HU; Swanton, C; - view fewer (2017) Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters. Annals of Oncology , 28 (10) pp. 2472-2480. 10.1093/annonc/mdx355.

Litchfield, K; Levy, M; Orlando, G; Loveday, C; Law, PJ; Migliorini, G; Holroyd, A; ... Turnbull, C; + view all Litchfield, K; Levy, M; Orlando, G; Loveday, C; Law, PJ; Migliorini, G; Holroyd, A; Broderick, P; Karlsson, R; Haugen, TB; Kristiansen, W; Nsengimana, J; Fenwick, K; Assiotis, I; Kote-Jarai, Z; Dunning, AM; Muir, K; Peto, J; Eeles, R; Easton, DF; Dudakia, D; Orr, N; Pashayan, N; Bishop, DT; Reid, A; Huddart, RA; Shipley, J; Grotmol, T; Wiklund, F; Houlston, RS; Turnbull, C; - view fewer (2017) Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. Nature Genetics , 49 (7) pp. 1133-1140. 10.1038/ng.3896.

Litchfield, K; Turajlic, S; Swanton, C; (2017) The GENIE Is Out of the Bottle: Landmark Cancer Genomics Dataset Released. Cancer Discovery , 7 (8) pp. 796-798. 10.1158/2159-8290.CD-17-0604.

Liu, TH; Tang, YJ; Huang, Y; Wang, L; Guo, XL; Mi, JQ; Liu, LG; ... Hong, DL; + view all Liu, TH; Tang, YJ; Huang, Y; Wang, L; Guo, XL; Mi, JQ; Liu, LG; Zhu, H; Zhang, Y; Chen, L; Liu, X; Zhang, LH; Ye, QJ; Li, BS; Tang, JY; Ford, A; Enver, T; Liu, F; Chen, GQ; Hong, DL; - view fewer (2017) Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin. Leukemia , 31 (5) pp. 1079-1086. 10.1038/leu.2016.313.

Llombart, V; Alejandro Trejo, S; Bronsoms, S; Morancho, A; Ma, F; Faura, J; Garcia-Berrocoso, T; ... Montaner, J; + view all Llombart, V; Alejandro Trejo, S; Bronsoms, S; Morancho, A; Ma, F; Faura, J; Garcia-Berrocoso, T; Simats, A; Rosell, A; Canals, F; Hernandez-Guillamon, M; Montaner, J; - view fewer (2017) Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry. Journal of Proteomics , 152 pp. 243-253. 10.1016/j.jprot.2016.11.014.

Lopez-Garcia, C; Sansregret, L; Domingo, E; McGranahan, N; Hobor, S; Birkbak, NJ; Horswell, S; ... Swanton, C; + view all Lopez-Garcia, C; Sansregret, L; Domingo, E; McGranahan, N; Hobor, S; Birkbak, NJ; Horswell, S; Gronroos, E; Favero, F; Rowan, AJ; Matthews, N; Begum, S; Phillimore, B; Burrell, R; Oukrif, D; Spencer-Dene, B; Kovac, M; Stamp, G; Stewart, A; Danielsen, H; Novelli, M; Tomlinson, I; Swanton, C; - view fewer (2017) BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer. Cancer Cell , 31 (1) pp. 79-93. 10.1016/j.ccell.2016.11.001.

Lowdell, MW; Thomas, A; (2017) The expanding role of the clinical haematologist in the new world of advanced therapy medicinal products. British Journal of Haematology , 176 (1) pp. 9-15. 10.1111/bjh.14384.

Maccari, G; Robinson, J; Ballingall, K; Guethlein, LA; Grimholt, U; Kaufman, J; Ho, CS; ... Marsh, SG; + view all Maccari, G; Robinson, J; Ballingall, K; Guethlein, LA; Grimholt, U; Kaufman, J; Ho, CS; de Groot, NG; Flicek, P; Bontrop, RE; Hammond, JA; Marsh, SG; - view fewer (2017) IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Research , 45 (D1) D860-D864. 10.1093/nar/gkw1050.

Maciocia, N; Melville, A; Cheesman, S; Sharpley, F; Ramasamy, K; Streetly, M; Jenner, M; ... Rabin, N; + view all Maciocia, N; Melville, A; Cheesman, S; Sharpley, F; Ramasamy, K; Streetly, M; Jenner, M; Benjamin, R; Schey, S; Maciocia, P; Popat, R; D'sa, S; Rismani, A; Cerner, A; Yong, K; Rabin, N; - view fewer (2017) Real-world use of pomalidomide and dexamethasone in double refractory multiple myeloma suggests benefit in renal impairment and adverse genetics: a multi-centre UK experience. British Journal of Haematology , 176 (6) pp. 908-917. 10.1111/bjh.14547.

Maciocia, PM; Wawrzyniecka, PA; Akarca, AU; Philip, B; Ricciardelli, I; Somja, J; Onuoha, SC; ... Pule, MA; + view all Maciocia, PM; Wawrzyniecka, PA; Akarca, AU; Philip, B; Ricciardelli, I; Somja, J; Onuoha, SC; Legut, M; Cole, DK; Sewell, AK; Gritti, G; Piris, MA; Peggs, KS; Linch, DC; Marafioti, T; Pule, MA; - view fewer (2017) Targeting T-cell receptor β-constant region for immunotherapy of T-cell malignancies. Nature Medicine , 23 (12) pp. 1416-1423. 10.1038/nm.4444.

Majeed, F; Yar, T; Alsunni, A; Alhawaj, AF; AlRahim, A; Alzaki, M; (2017) Synergistic effect of energy drinks and overweight/obesity on cardiac autonomic testing using the Valsalva maneuver in university students. Annals of Saudi Medicine , 37 (3) pp. 181-188. 10.5144/0256-4947.2017.181.

Makanyanga, J; Ganeshan, B; Rodriguez-Justo, M; Bhatnagar, G; Groves, A; Halligan, S; Miles, K; Makanyanga, J; Ganeshan, B; Rodriguez-Justo, M; Bhatnagar, G; Groves, A; Halligan, S; Miles, K; Taylor, SA; - view fewer (2017) MRI texture analysis (MRTA) of T2-weighted images in Crohn's disease may provide information on histological and MRI disease activity in patients undergoing ileal resection. European Radiology , 27 (2) pp. 589-598. 10.1007/s00330-016-4324-4.

Maley, CC; Aktipis, A; Graham, TA; Sottoriva, A; Boddy, AM; Janiszewska, M; Silva, AS; ... Shibata, D; + view all Maley, CC; Aktipis, A; Graham, TA; Sottoriva, A; Boddy, AM; Janiszewska, M; Silva, AS; Gerlinger, M; Yuan, Y; Pienta, KJ; Anderson, KS; Gatenby, R; Swanton, C; Posada, D; Wu, C-I; Schiffman, JD; Hwang, ES; Polyak, K; Anderson, ARA; Brown, JS; Greaves, M; Shibata, D; - view fewer (2017) Classifying the evolutionary and ecological features of neoplasms. Nature Reviews Cancer , 17 (10) pp. 605-619. 10.1038/nrc.2017.69.

Marchetti, C; Kristeleit, R; McCormack, M; Mould, T; Olaitan, A; Widschwendter, M; MacDonald, N; Marchetti, C; Kristeleit, R; McCormack, M; Mould, T; Olaitan, A; Widschwendter, M; MacDonald, N; Ledermann, JA; - view fewer (2017) Outcome of patients with advanced ovarian cancer who do not undergo debulking surgery: A single institution retrospective review. Gynecologic Oncology , 144 (1) pp. 57-60. 10.1016/j.ygyno.2016.11.001.

Mardakheh, FK; Sailem, HZ; Kümper, S; Tape, CJ; McCully, RR; Paul, A; Anjomani-Virmouni, S; ... Bakal, C; + view all Mardakheh, FK; Sailem, HZ; Kümper, S; Tape, CJ; McCully, RR; Paul, A; Anjomani-Virmouni, S; Jørgensen, C; Poulogiannis, G; Marshall, CJ; Bakal, C; - view fewer (2017) Proteomics profiling of interactome dynamics by colocalisation analysis (COLA). Molecular BioSystems , 13 (1) pp. 92-105. 10.1039/c6mb00701e.

Marlein, CR; Zaitseva, L; Piddock, RE; Robinson, SD; Edwards, DR; Shafat, MS; Zhou, Z; ... Rushworth, SA; + view all Marlein, CR; Zaitseva, L; Piddock, RE; Robinson, SD; Edwards, DR; Shafat, MS; Zhou, Z; Lawes, M; Bowles, KM; Rushworth, SA; - view fewer (2017) NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts. Blood , 130 (14) pp. 1649-1660. 10.1182/blood-2017-03-772939.

Marsh, SG; (2017) Nomenclature for factors of the HLA system, update December 2016. Human Immunology , 78 (3) pp. 316-321. 10.1016/j.humimm.2017.01.009.

Marsh, SG; (2017) Nomenclature for factors of the HLA system, update November 2016. Human Immunology , 78 (3) pp. 306-315. 10.1016/j.humimm.2017.01.008.

Marsh, SG; (2017) Nomenclature for factors of the HLA system, update October 2016. Human Immunology , 78 (3) pp. 294-305. 10.1016/j.humimm.2017.01.007.

Marth, C; Vergote, I; Scambia, G; Oberaigner, W; Clamp, A; Berger, R; Kurzeder, C; ... Bach, BA; + view all Marth, C; Vergote, I; Scambia, G; Oberaigner, W; Clamp, A; Berger, R; Kurzeder, C; Colombo, N; Vuylsteke, P; Lorusso, D; Hall, M; Renard, V; Pignata, S; Kristeleit, R; Altintas, S; Rustin, G; Wenham, RM; Mirza, MR; Fong, PC; Oza, A; Monk, BJ; Ma, H; Vogl, FD; Bach, BA; - view fewer (2017) ENGOT-ov-6/TRINOVA-2: Randomised, double-blind, phase 3 study of pegylated liposomal doxorubicin plus trebananib or placebo in women with recurrent partially platinum-sensitive or resistant ovarian cancer. European Journal of Cancer , 70 pp. 111-121. 10.1016/j.ejca.2016.09.004.

Martin, L-A; Ribas, R; Simigdala, N; Schuster, E; Pancholi, S; Tenev, T; Gellert, P; ... Dowsett, M; + view all Martin, L-A; Ribas, R; Simigdala, N; Schuster, E; Pancholi, S; Tenev, T; Gellert, P; Buluwela, L; Harrod, A; Thornhill, A; Nikitorowicz-Buniak, J; Bhamra, A; Turgeon, M-O; Poulogiannis, G; Gao, Q; Martins, V; Hills, M; Garcia-Murillas, I; Fribbens, C; Patani, N; Li, Z; Sikora, MJ; Turner, N; Zwart, W; Oesterreich, S; Carroll, J; Ali, S; Dowsett, M; - view fewer (2017) Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance. Nature Communications , 8 , Article 1865. 10.1038/s41467-017-01864-y.

Martinelli, G; Boissel, N; Chevallier, P; Ottmann, O; Goekbuget, N; Topp, MS; Fielding, AK; ... Stein, A; + view all Martinelli, G; Boissel, N; Chevallier, P; Ottmann, O; Goekbuget, N; Topp, MS; Fielding, AK; Rambaldi, A; Ritchie, EK; Papayannidis, C; Sterling, LR; Benjamin, J; Stein, A; - view fewer (2017) Complete Hematologic and Molecular Response in Adult Patients With Relapsed/Refractory Philadelphia Chromosome-Positive B-Precursor Acute Lymphoblastic Leukemia Following Treatment With Blinatumomab: Results From a Phase II, Single-Arm, Multicenter Study. Journal of Clinical Oncology , 35 (16) pp. 1795-1802. 10.1200/JCO.2016.69.3531.

Martinez, C; Gayoso, J; Canals, C; Finel, H; Peggs, K; Dominietto, A; Castagna, L; ... Sureda, A; + view all Martinez, C; Gayoso, J; Canals, C; Finel, H; Peggs, K; Dominietto, A; Castagna, L; Afanasyev, B; Robinson, S; Blaise, D; Corradini, P; Itala-Remes, M; Bermudez, A; Forcade, E; Russo, D; Potter, M; McQuaker, G; Yakoub-Agha, I; Scheid, C; Bloor, A; Montoto, S; Dreger, P; Sureda, A; - view fewer (2017) Post-Transplantation Cyclophosphamide-Based Haploidentical Transplantation as Alternative to Matched Sibling or Unrelated Donor Transplantation for Hodgkin Lymphoma: A Registry Study of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation. Journal of Clinical Oncology , 35 (30) pp. 3425-3432. 10.1200/JCO.2017.72.6869.

Mason, MD; Clarke, NW; James, ND; Dearnaley, DP; Spears, MR; Ritchie, AWS; Attard, G; ... STAMPEDE Investigators, .; + view all Mason, MD; Clarke, NW; James, ND; Dearnaley, DP; Spears, MR; Ritchie, AWS; Attard, G; Cross, W; Jones, RJ; Parker, CC; Russell, JM; Thalmann, GN; Schiavone, F; Cassoly, E; Matheson, D; Millman, R; Rentsch, CA; Barber, J; Gilson, C; Ibrahim, A; Logue, J; Lydon, A; Nikapota, AD; O'Sullivan, JM; Porfiri, E; Protheroe, A; Srihari, NN; Tsang, D; Wagstaff, J; Wallace, J; Walmsley, C; Parmar, MKB; Sydes, MR; STAMPEDE Investigators, .; - view fewer (2017) Adding Celecoxib With or Without Zoledronic Acid for Hormone-Naïve Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial. Journal of Clincal Oncology , 35 (14) pp. 1530-1541. 10.1200/JCO.2016.69.0677.

Massard, C; Mateo, J; Loriot, Y; Pezaro, C; Albiges, L; Mehra, N; Varga, A; ... de Bono, J; + view all Massard, C; Mateo, J; Loriot, Y; Pezaro, C; Albiges, L; Mehra, N; Varga, A; Bianchini, D; Ryan, CJ; Petrylak, DP; Attard, G; Shen, L; Fizazi, K; de Bono, J; - view fewer (2017) Phase I/II trial of cabazitaxel plus abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel and abiraterone. Annals of Oncology , 28 (1) pp. 90-95. 10.1093/annonc/mdw441.

Matalonga, J; Glaria, E; Bresque, M; Escande, C; Carbó, JM; Kiefer, K; Vicente, R; ... Valledor, AF; + view all Matalonga, J; Glaria, E; Bresque, M; Escande, C; Carbó, JM; Kiefer, K; Vicente, R; León, TE; Beceiro, S; Pascual-García, M; Serret, J; Sanjurjo, L; Morón-Ros, S; Riera, A; Paytubi, S; Juarez, A; Sotillo, F; Lindbom, L; Caelles, C; Sarrias, M-R; Sancho, J; Castrillo, A; Chini, EN; Valledor, AF; - view fewer (2017) The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism. Cell Reports , 18 (5) pp. 1241-1255. 10.1016/j.celrep.2017.01.007.

Mateo, J; Ganji, G; Lemech, C; Burris, HA; Han, S-W; Swales, K; Decordova, S; ... Arkenau, H-T; + view all Mateo, J; Ganji, G; Lemech, C; Burris, HA; Han, S-W; Swales, K; Decordova, S; DeYoung, MP; Smith, DA; Kalyana-Sundaram, S; Wu, J; Motwani, M; Kumar, R; Tolson, JM; Rha, SY; Chung, HC; Eder, JP; Sharma, S; Bang, Y-J; Infante, JR; Yan, L; de Bono, JS; Arkenau, H-T; - view fewer (2017) A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors. Clinical Cancer Research , 23 (19) pp. 5981-5992. 10.1158/1078-0432.CCR-17-0725.

Mattar, CNZ; Gil-Farina, I; Rosales, C; Johana, N; Tan, YYW; McIntosh, J; Kaeppel, C; ... Chan, JKY; + view all Mattar, CNZ; Gil-Farina, I; Rosales, C; Johana, N; Tan, YYW; McIntosh, J; Kaeppel, C; Waddington, SN; Biswas, A; Choolani, M; Schmidt, M; Nathwani, AC; Chan, JKY; - view fewer (2017) In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model. Molecular Therapy , 25 (8) pp. 1843-1853. 10.1016/j.ymthe.2017.04.003.

Maughan, EF; Butler, CR; Crowley, C; Teoh, GZ; Hondt, MD; Hamilton, NJ; Hynds, RE; ... Elliott, MJ; + view all Maughan, EF; Butler, CR; Crowley, C; Teoh, GZ; Hondt, MD; Hamilton, NJ; Hynds, RE; Lange, P; Ansari, T; Urbani, L; Janes, SM; De Coppi, P; Birchall, MA; Elliott, MJ; - view fewer (2017) A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model. The Laryngoscope , 127 (12) E449-E457. 10.1002/lary.26611.

Maughan, EF; Hynds, RE; Proctor, TJ; Janes, SM; Elliott, M; Birchall, MA; Lowdell, MW; Maughan, EF; Hynds, RE; Proctor, TJ; Janes, SM; Elliott, M; Birchall, MA; Lowdell, MW; De Coppi, P; - view fewer (2017) Autologous Cell Seeding in Tracheal Tissue Engineering. Current Stem Cell Reports , 3 (4) pp. 279-289. 10.1007/s40778-017-0108-2.

Mavroudis, CA; Eleftheriou, D; Hong, Y; Majumder, B; Koganti, S; Sapsford, R; North, J; ... Rakhit, RD; + view all Mavroudis, CA; Eleftheriou, D; Hong, Y; Majumder, B; Koganti, S; Sapsford, R; North, J; Lowdell, M; Klein, N; Brogan, P; Rakhit, RD; - view fewer (2017) Microparticles in acute coronary syndrome. Thrombosis Research , 156 pp. 109-116. 10.1016/j.thromres.2017.06.003.

McDaniel, AS; Ferraldeschi, R; Krupa, R; Landers, M; Graf, R; Louw, J; Jendrisak, A; ... Attard, G; + view all McDaniel, AS; Ferraldeschi, R; Krupa, R; Landers, M; Graf, R; Louw, J; Jendrisak, A; Bales, N; Marrinucci, D; Zafeiriou, Z; Flohr, P; Sideris, S; Crespo, M; Figueiredo, I; Mateo, J; de Bono, JS; Dittamore, R; Tomlins, SA; Attard, G; - view fewer (2017) Phenotypic diversity of circulating tumour cells in patients with metastatic castration-resistant prostate cancer. BJU International , 120 (5B) E30-E44. 10.1111/bju.13631.

McGranahan, N; Rosenthal, R; Hiley, CT; Rowan, AJ; Watkins, TBK; Wilson, GA; Birkbak, NJ; ... Swanton, C; + view all McGranahan, N; Rosenthal, R; Hiley, CT; Rowan, AJ; Watkins, TBK; Wilson, GA; Birkbak, NJ; Veeriah, S; Van Loo, P; Herrero, J; Swanton, C; - view fewer (2017) Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. Cell 10.1016/j.cell.2017.10.001. (In press).

McGranahan, N; Swanton, C; (2017) Cancer Evolution Constrained by the Immune Microenvironment. CELL , 170 (5) pp. 825-827. 10.1016/j.cell.2017.08.012.

McGranahan, N; Swanton, C; (2017) Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future. Cell , 168 (4) pp. 613-628. 10.1016/j.cell.2017.01.018.

McNamara, MG; Bridgewater, J; Lopes, A; Wasan, H; Malka, D; Jensen, LH; Okusaka, T; ... Valle, JW; + view all McNamara, MG; Bridgewater, J; Lopes, A; Wasan, H; Malka, D; Jensen, LH; Okusaka, T; Knox, JJ; Wagner, D; Cunningham, D; Shannon, J; Goldstein, D; Moehler, M; Bekaii-Saab, T; Valle, JW; - view fewer (2017) Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials. BMC Cancer , 17 , Article 262. 10.1186/s12885-017-3266-9.

Megias, D; Phillips, M; Clifton-Hadley, L; Harron, E; Eaton, DJ; Sanghera, P; Whitfield, G; (2017) Dose specification for hippocampal sparing whole brain radiotherapy (HS WBRT): considerations from the UK HIPPO trial QA programme. British Journal Of Radiology , 90 (1071) , Article 20160829. 10.1259/bjr.20160829.

Mehta, A; Belmatoug, N; Bembi, B; Deegan, P; Elstein, D; Göker-Alpan, Ö; Lukina, E; ... Hughes, D; + view all Mehta, A; Belmatoug, N; Bembi, B; Deegan, P; Elstein, D; Göker-Alpan, Ö; Lukina, E; Mengel, E; Nakamura, K; Pastores, GM; López, JP; Schwartz, I; Serratrice, C; Szer, J; Zimran, A; Di Rocco, M; Panahloo, Z; Kuter, DJ; Hughes, D; - view fewer (2017) Exploring the patient journey to diagnosis of Gaucher disease from the perspective of 212 patients with Gaucher disease and 16 Gaucher expert physicians. Molecular Genetics and Metabolism , 122 (3) pp. 122-129. 10.1016/j.ymgme.2017.08.002.

Mesquita, B; Rothwell, DG; Burt, DJ; Chemi, F; Fernandez-Gutierrez, F; Slane-Tan, D; Antonello, J; ... Brady, G; + view all Mesquita, B; Rothwell, DG; Burt, DJ; Chemi, F; Fernandez-Gutierrez, F; Slane-Tan, D; Antonello, J; Carter, M; Carter, L; Parry, M; Franklin, L; Marais, R; Blackhall, F; Dive, C; Brady, G; - view fewer (2017) Molecular analysis of single circulating tumour cells following long-term storage of clinical samples. Molecular Oncology , 11 (12) pp. 1687-1697. 10.1002/1878-0261.12113.

Meyer, T; Fox, R; Ma, YT; Ross, PJ; James, MW; Sturgess, R; Stubbs, C; ... Palmer, DH; + view all Meyer, T; Fox, R; Ma, YT; Ross, PJ; James, MW; Sturgess, R; Stubbs, C; Stocken, DD; Wall, L; Watkinson, A; Hacking, N; Evans, TRJ; Collins, P; Hubner, RA; Cunningham, D; Primrose, JN; Johnson, PJ; Palmer, DH; - view fewer (2017) Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial. The Lancet Gastroenterology and Hepatology , 2 (8) pp. 565-575. 10.1016/S2468-1253(17)30156-5.

Meyer, T; Palmer, DH; Cheng, A-L; Hocke, J; Loembé, A-B; Yen, C-J; (2017) mRECIST to predict survival in advanced hepatocellular carcinoma: Analysis of two randomised phase II trials comparing nintedanib vs sorafenib. Liver International , 37 (7) pp. 1047-1055. 10.1111/liv.13359.

Migueles, RP; Shaw, L; Rodrigues, NP; May, G; Henseleit, K; Anderson, KGV; Goker, H; ... Enver, T; + view all Migueles, RP; Shaw, L; Rodrigues, NP; May, G; Henseleit, K; Anderson, KGV; Goker, H; Jones, CM; de Bruijn, MFTR; Brickman, JM; Enver, T; - view fewer (2017) Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny. Developmental Biology , 424 (2) pp. 236-245. 10.1016/j.ydbio.2016.12.021.

Milani, A; Kristeleit, R; McCormack, M; Raja, F; Luvero, D; Widschwendter, M; MacDonald, N; ... Ledermann, JA; + view all Milani, A; Kristeleit, R; McCormack, M; Raja, F; Luvero, D; Widschwendter, M; MacDonald, N; Mould, T; Olatain, A; Hackshaw, A; Ledermann, JA; - view fewer (2017) Switching from standard to dose-dense chemotherapy in front-line treatment of advanced ovarian cancer: a retrospective study of feasibility and efficacy. ESMO Open , 1 (6) , Article e000117. 10.1136/esmoopen-2016-000117.

Miles, A; Chronakis, I; Fox, J; Mayer, A; (2017) Use of a computerised decision aid (DA) to inform the decision process on adjuvant chemotherapy in patients with stage II colorectal cancer: development and preliminary evaluation. BMJ OPEN , 7 (3) , Article e012935. 10.1136/bmjopen-2016-012935.

Miller, PDE; de Silva, T; Skinner, R; Gilleece, M; Peniket, A; Hamblin, A; Greenfield, D; ... Snowden, JA; + view all Miller, PDE; de Silva, T; Skinner, R; Gilleece, M; Peniket, A; Hamblin, A; Greenfield, D; Anthias, C; Peggs, K; Madrigal, A; Snowden, JA; - view fewer (2017) Routine vaccination practice after adult and paediatric allogeneic haematopoietic stem cell transplant: a survey of UK NHS programmes. Bone Marrow Transplantation , 52 pp. 775-777. 10.1038/bmt.2016.362.

Miller, RE; Ledermann, JA; (2017) The European Society for Medical Oncology (ESMO) Congress 2016: Highlights and summary of selected abstracts in gynecologic cancers. Gynecologic Oncology , 144 (1) pp. 8-10. 10.1016/j.ygyno.2016.11.040.

Mladenovic, J; Susnjar, S; Tanic, M; Jankovic, R; Karadzic, K; Gavrilovic, D; Stojanovic, S; Mladenovic, J; Susnjar, S; Tanic, M; Jankovic, R; Karadzic, K; Gavrilovic, D; Stojanovic, S; Plesinac-Karapandzic, V; - view fewer (2017) Tumor response and patient outcome after preoperative radiotherapy in locally advanced non-inflammatory breast cancer patients. Journal of B.U.ON. : official journal of the Balkan Union of Oncology , 22 (2) pp. 325-333.

Mlcochova, P; Sutherland, KA; Watters, SA; Bertoli, C; de Bruin, RAM; Rehwinkel, J; Neil, SJ; ... Gupta, RK; + view all Mlcochova, P; Sutherland, KA; Watters, SA; Bertoli, C; de Bruin, RAM; Rehwinkel, J; Neil, SJ; Lenzi, GM; Kim, B; Khwaja, A; Gage, MC; Georgiou, C; Chittka, A; Yona, S; Noursadeghi, M; Towers, GJ; Gupta, RK; - view fewer (2017) A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages. The EMBO Journal , 36 (5) pp. 604-616. 10.15252/embj.201696025.

Moiseeva, V; Amelina, H; Collopy, LC; Armstrong, CA; Pearson, SR; Tomita, K; (2017) The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast. Cell Discovery , 3 , Article 17041. 10.1038/celldisc.2017.41.

Moniz, LS; Surinova, S; Ghazaly, E; Velasco, LG; Haider, S; Rodriguez-Prados, JC; Berenjeno, IM; ... Vanhaesebroeck, B; + view all Moniz, LS; Surinova, S; Ghazaly, E; Velasco, LG; Haider, S; Rodriguez-Prados, JC; Berenjeno, IM; Chelala, C; Vanhaesebroeck, B; - view fewer (2017) Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate. Scientific Reports , 7 (39985) 10.1038/srep39985.

Montgomery, HE; Haines, A; Marlow, N; Pearson, G; Mythen, MG; Grocott, MPW; Swanton, C; (2017) The future of UK healthcare: problems and potential solutions to a system in crisis. [Review]. Annals of Oncology , 28 (8) pp. 1751-1755. 10.1093/annonc/mdx136.

Moorcraft, SY; Jones, T; Walker, BA; Ladas, G; Kalaitzaki, E; Yuan, L; Begum, R; ... Chau, I; + view all Moorcraft, SY; Jones, T; Walker, BA; Ladas, G; Kalaitzaki, E; Yuan, L; Begum, R; Eltahir, Z; Wotherspoon, A; Montero-Fernandez, A; Teixeira Mendes, LS; de Castro, DG; Hulkki Wilson, S; Proszek, P; To, YM; Hawkes, E; Roy, A; Cunningham, D; Rao, S; Watkins, D; Starling, N; Bowcock, AM; Chau, I; - view fewer (2017) Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment. Oncotarget , 8 (39) pp. 64999-65008. 10.18632/oncotarget.17048.

Morris, EC; Fox, T; Chakraverty, R; Tendeiro, R; Snell, K; Rivat, C; Grace, S; ... Thrasher, AJ; + view all Morris, EC; Fox, T; Chakraverty, R; Tendeiro, R; Snell, K; Rivat, C; Grace, S; Gilmour, K; Workman, S; Buckland, K; Butler, K; Chee, R; Salama, AD; Ibrahim, H; Hara, H; Duret, C; Mavilio, F; Male, F; Bushman, FD; Galy, A; Burns, SO; Gaspar, HB; Thrasher, AJ; - view fewer (2017) Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult. Blood , 130 pp. 1327-1335. 10.1182/blood-2017-04-777136.

Morrissy, AS; Cavalli, FMG; Remke, M; Ramaswamy, V; Shih, DJH; Holgado, BL; Farooq, H; ... Taylor, MD; + view all Morrissy, AS; Cavalli, FMG; Remke, M; Ramaswamy, V; Shih, DJH; Holgado, BL; Farooq, H; Donovan, LK; Garzia, L; Agnihotri, S; Kiehna, EN; Mercier, E; Mayoh, C; Papillon-Cavanagh, S; Nikbakht, H; Gayden, T; Torchia, J; Picard, D; Merino, DM; Vladoiu, M; Luu, B; Wu, X; Daniels, C; Horswell, S; Thompson, YY; Hovestadt, V; Northcott, PA; Jones, DTW; Peacock, J; Wang, X; Mack, SC; Reimand, J; Albrecht, S; Fontebasso, AM; Thiessen, N; Li, Y; Schein, JE; Lee, D; Carlsen, R; Mayo, M; Tse, K; Tam, A; Dhalla, N; Ally, A; Chuah, E; Cheng, Y; Plettner, P; Li, HI; Corbett, RD; Wong, T; Long, W; Loukides, J; Buczkowicz, P; Hawkins, CE; Tabori, U; Rood, BR; Myseros, JS; Packer, RJ; Korshunov, A; Lichter, P; Kool, M; Pfister, SM; Schueller, U; Dirks, P; Huang, A; Bouffet, E; Rutka, JT; Bader, GD; Swanton, C; Ma, Y; Moore, RA; Mungall, AJ; Majewski, J; Jones, SJM; Das, S; Malkin, D; Jabado, N; Marra, MA; Taylor, MD; - view fewer (2017) Spatial heterogeneity in medulloblastoma. Nature Genetics , 49 (5) pp. 780-788. 10.1038/ng.3838.

Moschetta, M; Mak, G; Hauser, J; Davies, C; Uccello, M; Arkenau, HT; (2017) Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI-H) metastatic endometrial cancer. Experimental Hematology & Oncology , 6 (1) , Article 1. 10.1186/s40164-016-0061-2.

Mughal, S; Moghul, I; Yu, J; Clark, T; Gregory, DS; Pontikos, N; (2017) Pheno4J: a gene to phenotype graph database. Bioinformatics , 33 (20) pp. 3317-3319. 10.1093/bioinformatics/btx397.

Mukherjee, S; Hurt, CN; Gwynne, S; Sebag-Montefiore, D; Radhakrishna, G; Gollins, S; Hawkins, M; ... Crosby, T; + view all Mukherjee, S; Hurt, CN; Gwynne, S; Sebag-Montefiore, D; Radhakrishna, G; Gollins, S; Hawkins, M; Grabsch, HI; Jones, G; Falk, S; Sharma, R; Bateman, A; Roy, R; Ray, R; Canham, J; Griffiths, G; Maughan, T; Crosby, T; - view fewer (2017) NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma. European Journal of Cancer , 74 pp. 38-46. 10.1016/j.ejca.2016.11.031.

Nacheva, E; Mokretar, K; Soenmez, A; Pittman, AM; Grace, C; Valli, R; Ejaz, A; ... Proukakis, C; + view all Nacheva, E; Mokretar, K; Soenmez, A; Pittman, AM; Grace, C; Valli, R; Ejaz, A; Vattathil, S; Maserati, E; Houlden, H; Taanman, J-W; Schapira, AH; Proukakis, C; - view fewer (2017) DNA isolation protocol effects on nuclear DNA analysis by microarrays, droplet digital PCR, and whole genome sequencing, and on mitochondrial DNA copy number estimation. PLoS One , 12 (7) , Article e0180467. 10.1371/journal.pone.0180467.

Nathwani, AC; Davidoff, AM; Tuddenham, EGD; (2017) Advances in Gene Therapy for Haemophilia. Hum Gene Ther 10.1089/hum.2017.167.

Nathwani, AC; Davidoff, AM; Tuddenham, EGD; (2017) Gene Therapy for Hemophilia. Hematology/Oncology Clinics of North America , 31 (5) pp. 853-868. 10.1016/j.hoc.2017.06.011.

Naxerova, K; Reiter, JG; Brachtel, E; Lennerz, JK; van de Wetering, M; Rowan, A; Cai, T; ... Jain, RK; + view all Naxerova, K; Reiter, JG; Brachtel, E; Lennerz, JK; van de Wetering, M; Rowan, A; Cai, T; Clevers, H; Swanton, C; Nowak, MA; Elledge, SJ; Jain, RK; - view fewer (2017) Origins of lymphatic and distant metastases in human colorectal cancer. Science , 357 (6346) pp. 55-60. 10.1126/science.aai8515.

Neoptolemos, JP; Palmer, DH; Ghaneh, P; Psarelli, EE; Valle, JW; Halloran, CM; Faluyi, O; ... European Study Group for Pancreatic Cancer, .; + view all Neoptolemos, JP; Palmer, DH; Ghaneh, P; Psarelli, EE; Valle, JW; Halloran, CM; Faluyi, O; O'Reilly, DA; Cunningham, D; Wadsley, J; Darby, S; Meyer, T; Gillmore, R; Anthoney, A; Lind, P; Glimelius, B; Falk, S; Izbicki, JR; Middleton, GW; Cummins, S; Ross, PJ; Wasan, H; McDonald, A; Crosby, T; Ma, YT; Patel, K; Sherriff, D; Soomal, R; Borg, D; Sothi, S; Hammel, P; Hackert, T; Jackson, R; Büchler, MW; European Study Group for Pancreatic Cancer, .; - view fewer (2017) Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet , 389 (10073) pp. 1011-1024. 10.1016/S0140-6736(16)32409-6.

Ng, K; Joury, S; Gillmore, R; (2017) Oncology admissions to the intensive care unit: what factors should influence the decision? [Letter]. Clinical Medicine , 17 (4) p. 375. 10.7861/clinmedicine.17-4-375.

Ngwenya, N; Kenten, C; Jones, L; Gibson, F; Pearce, S; Flatley, M; Hough, R; ... Whelan, J; + view all Ngwenya, N; Kenten, C; Jones, L; Gibson, F; Pearce, S; Flatley, M; Hough, R; Stirling, LC; Taylor, RM; Wong, G; Whelan, J; - view fewer (2017) Experiences and Preferences for End-of-Life Care for Young Adults with Cancer and Their Informal Carers: A Narrative Synthesis. Journal of Adolescent and Young Adult Oncology , 6 (2) pp. 200-212. 10.1089/jayao.2016.0055.

Nienhuis, AW; Nathwani, AC; Davidoff, AM; (2017) Gene Therapy for Hemophilia. [Review]. Molecular Therapy , 25 (5) pp. 1163-1167. 10.1016/j.ymthe.2017.03.033.

Nunes, JPM; Vassileva, V; Robinson, E; Morais, M; Smith, MEB; Pedley, RB; Caddick, S; ... Chudasama, V; + view all Nunes, JPM; Vassileva, V; Robinson, E; Morais, M; Smith, MEB; Pedley, RB; Caddick, S; Baker, JR; Chudasama, V; - view fewer (2017) Use of a next generation maleimide in combination with THIOMAB (TM) antibody technology delivers a highly stable, potent and near homogeneous THIOMAB (TM) antibody-drug conjugate (TDC). RSC ADVANCES , 7 (40) pp. 24828-24832. 10.1039/c7ra04606e.

O'Connor, D; Moorman, AV; Wade, R; Hancock, J; Tan, RMR; Bartram, J; Moppett, J; ... Samarasinghe, S; + view all O'Connor, D; Moorman, AV; Wade, R; Hancock, J; Tan, RMR; Bartram, J; Moppett, J; Schwab, C; Patrick, K; Harrison, CJ; Hough, R; Goulden, N; Vora, A; Samarasinghe, S; - view fewer (2017) Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia. Journal of Clinical Oncology , 35 (6) pp. 660-667. 10.1200/JCO.2016.69.6278.

Oakes, T; Heather, JM; Best, K; Byng-Maddick, R; Husovsky, C; Ismail, M; Joshi, K; ... Chain, B; + view all Oakes, T; Heather, JM; Best, K; Byng-Maddick, R; Husovsky, C; Ismail, M; Joshi, K; Maxwell, G; Noursadeghi, M; Riddell, N; Ruehl, T; Turner, CT; Uddin, I; Chain, B; - view fewer (2017) Quantitative Characterization of the T Cell Receptor Repertoire of Naive and Memory subsets Using an Integrated experimental and Computational Pipeline Which Is Robust, economical, and Versatile. Frontiers in Immunology , 8 , Article 1267. 10.3389/fimmu.2017.01267.

Oakes, T; Popple, AL; Williams, J; Best, K; Heather, JM; Ismail, M; Maxwell, G; ... Chain, B; + view all Oakes, T; Popple, AL; Williams, J; Best, K; Heather, JM; Ismail, M; Maxwell, G; Gellatly, N; Dearman, RJ; Kimber, I; Chain, B; - view fewer (2017) The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors. Frontiers in Immunology , 8 , Article 162. 10.3389/fimmu.2017.00162.

Oka, A; Asano, Y; Hasegawa, M; Fujimoto, M; Ishikawa, O; Kuwana, M; Kawaguchi, Y; ... Ihn, H; + view all Oka, A; Asano, Y; Hasegawa, M; Fujimoto, M; Ishikawa, O; Kuwana, M; Kawaguchi, Y; Yamamoto, T; Takahashi, H; Goto, D; Endo, H; Jinnin, M; Mano, S; Hosomichi, K; Mabuchi, T; Ueda, MT; Nakagawa, S; Beck, S; Bahram, S; Takehara, K; Sato, S; Ihn, H; - view fewer (2017) RXRB is a MHC-encoded susceptibility gene associated with anti-topoisomerase I antibody-positive systemic sclerosis. Journal of Investigative Dermatology , 137 (9) pp. 1878-1886. 10.1016/j.jid.2017.04.028.

Orrell, M; Yates, L; Leung, P; Kang, S; Hoare, Z; Whitaker, C; Burns, A; ... Orgeta, V; + view all Orrell, M; Yates, L; Leung, P; Kang, S; Hoare, Z; Whitaker, C; Burns, A; Knapp, M; Leroi, I; Moniz-Cook, E; Pearson, S; Simpson, S; Spector, A; Roberts, S; Russell, I; de Waal, H; Woods, RT; Orgeta, V; - view fewer (2017) The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomised controlled trial. PLoS Medicine , 14 (3) , Article e1002269. 10.1371/journal.pmed.1002269.

Ortiz-Zapater, E; Lee, RW; Owen, W; Weitsman, G; Fruhwirth, G; Dunn, RG; Neat, MJ; ... Santis, G; + view all Ortiz-Zapater, E; Lee, RW; Owen, W; Weitsman, G; Fruhwirth, G; Dunn, RG; Neat, MJ; McCaughan, F; Parker, P; Ng, T; Santis, G; - view fewer (2017) MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition. PLoS ONE , 12 (1) , Article e0170798. 10.1371/journal.pone.0170798.

Oza, AM; Tinker, AV; Oaknin, A; Shapira-Frommer, R; McNeish, IA; Swisher, EM; Ray-Coquard, I; ... Kristeleit, RS; + view all Oza, AM; Tinker, AV; Oaknin, A; Shapira-Frommer, R; McNeish, IA; Swisher, EM; Ray-Coquard, I; Bell-McGuinn, K; Coleman, RL; O'Malley, DM; Leary, A; Chen, L-M; Provencher, D; Ma, L; Brenton, JD; Konecny, GE; Castro, CM; Giordano, H; Maloney, L; Goble, S; Lin, KK; Sun, J; Raponi, M; Rolfe, L; Kristeleit, RS; - view fewer (2017) Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2. Gynecologic Oncology , 147 (2) pp. 267-275. 10.1016/j.ygyno.2017.08.022.

Palmerini, E; Agostinelli, C; Picci, P; Pileri, S; Marafioti, T; Lollini, P-L; Scotlandi, K; ... Ferrari, S; + view all Palmerini, E; Agostinelli, C; Picci, P; Pileri, S; Marafioti, T; Lollini, P-L; Scotlandi, K; Longhi, A; Benassi, MS; Ferrari, S; - view fewer (2017) Tumoral immune-infiltrate (IF), PD-L1 expression and role of CD8/TIA-1 lymphocytes in localized osteosarcoma patients treated within protocol ISG-OS1. Oncotarget , 8 (67) pp. 111836-111846. 10.18632/oncotarget.22912.

Pan, S; Lai, H; Shen, Y; Breeze, C; Beck, S; Hong, T; Wang, C; Pan, S; Lai, H; Shen, Y; Breeze, C; Beck, S; Hong, T; Wang, C; Teschendorff, AE; - view fewer (2017) DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve. Cardiovascular Research , 113 (6) pp. 692-704. 10.1093/cvr/cvx050.

Parhizkar, M; Reardon, PJT; Knowles, JC; Browning, RJ; Stride, E; Pedley, RB; Grego, T; Parhizkar, M; Reardon, PJT; Knowles, JC; Browning, RJ; Stride, E; Pedley, RB; Grego, T; Edirisinghe, M; - view fewer (2017) Performance of novel high throughput multi electrospray systems for forming of polymeric micro/nanoparticles. Materials and Design , 126 pp. 73-84. 10.1016/j.matdes.2017.04.029.

Pastores, GM; Hughes, DA; (2017) Lysosomal Storage Disorders and Malignancy. Diseases , 5 (1) 10.3390/diseases5010008.

Pathania, M; De Jay, N; Maestro, N; Harutyunyan, AS; Nitarska, J; Pahlavan, P; Henderson, S; ... Salomoni, P; + view all Pathania, M; De Jay, N; Maestro, N; Harutyunyan, AS; Nitarska, J; Pahlavan, P; Henderson, S; Mikael, LG; Richard-Londt, A; Zhang, Y; Costa, JR; Hebert, S; Khazaei, S; Ibrahim, NS; Herrero, J; Riccio, A; Albrecht, S; Ketteler, R; Brandner, S; Kleinman, CL; Jabado, N; Salomoni, P; - view fewer (2017) H3.3(K27M) Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas. Cancer Cell , 32 (5) , Article e9. 10.1016/j.ccell.2017.09.014.

Paz-Ares, L; Forster, M; Boni, V; Szyldergemajn, S; Corral, J; Turnbull, S; Cubillo, A; ... Calvo, E; + view all Paz-Ares, L; Forster, M; Boni, V; Szyldergemajn, S; Corral, J; Turnbull, S; Cubillo, A; Teruel, CF; Calderero, IL; Siguero, M; Bohan, P; Calvo, E; - view fewer (2017) Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors. Investigational New Drugs , 35 (2) pp. 198-206. 10.1007/s10637-016-0410-3.

Pendsé, DA; Makanyanga, JC; Plumb, AA; Bhatnagar, G; Atkinson, D; Rodriguez-Justo, M; Halligan, S; Pendsé, DA; Makanyanga, JC; Plumb, AA; Bhatnagar, G; Atkinson, D; Rodriguez-Justo, M; Halligan, S; Taylor, SA; - view fewer (2017) Diffusion-weighted imaging for evaluating inflammatory activity in Crohn's disease: comparison with histopathology, conventional MRI activity scores, and faecal calprotectin. Abdominal Radiology , 42 (1) pp. 115-123. 10.1007/s00261-016-0863-z.

Pett, L; Kiakos, K; Satam, V; Patil, P; Laughlin-Toth, S; Gregory, M; Bowerman, M; ... Hartley, JA; + view all Pett, L; Kiakos, K; Satam, V; Patil, P; Laughlin-Toth, S; Gregory, M; Bowerman, M; Olson, K; Savagian, M; Lee, M; Lee, M; Wilson, WD; Hochhauser, D; Hartley, JA; - view fewer (2017) Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms , 1860 (5) pp. 617-629. 10.1016/j.bbagrm.2016.10.005.

Pezic, D; Weeks, SL; Hadjur, S; (2017) More to cohesin than meets the eye: complex diversity for fine-tuning of function. Current Opinion in Genetics & Development , 43 pp. 93-100. 10.1016/j.gde.2017.01.004.

Phillips, EH; Nash, S; Adedayo, T; Whelan, CJ; Fontana, M; Mahmood, S; Lachmann, HJ; ... Wechalekar, AD; + view all Phillips, EH; Nash, S; Adedayo, T; Whelan, CJ; Fontana, M; Mahmood, S; Lachmann, HJ; Gillmore, JD; Smith, P; Clifton-Hadley, L; Hawkins, PN; Wechalekar, AD; - view fewer (2017) Pitfalls in conducting prospective trials in stage III cardiac amyloidosis - experience from the REVEAL study. Amyloid , 24 (4) pp. 250-252. 10.1080/13506129.2017.1385453.

Pinder, SE; Campbell, AF; Bartlett, JMS; Marshall, A; Allen, D; Falzon, M; Dunn, JA; ... Stein, RC; + view all Pinder, SE; Campbell, AF; Bartlett, JMS; Marshall, A; Allen, D; Falzon, M; Dunn, JA; Makris, A; Hughes-Davies, L; Stein, RC; - view fewer (2017) Discrepancies in central review re-testing of patients with ER-positive and HER2-negative breast cancer in the OPTIMA prelim randomised clinical trial. British Journal of Cancer , 116 (7) pp. 859-863. 10.1038/bjc.2017.28.

Pontikos, N; Yu, J; Moghul, I; Withington, L; Blanco-Kelly, F; Vulliamy, T; Wong, TL; ... Plagnol, V; + view all Pontikos, N; Yu, J; Moghul, I; Withington, L; Blanco-Kelly, F; Vulliamy, T; Wong, TL; Murphy, C; Cipriani, V; Fiorentino, A; Arno, G; Greene, D; Jacobsen, JO; Clark, T; Gregory, DS; Nemeth, A; Halford, S; Inglehearn, CF; Downes, S; Black, GC; Webster, AR; Hardcastle, AJ; UKIRDC, .; Plagnol, V; - view fewer (2017) Phenopolis: an open platform for harmonization and analysis of genetic and phenotypic data. Bioinformatics , 33 (15) pp. 2421-2423. 10.1093/bioinformatics/btx147.

Porter, JB; Cappellini, MD; Kattamis, A; Viprakasit, V; Musallam, KM; Zhu, Z; Taher, AT; (2017) Iron overload across the spectrum of non-transfusion-dependent thalassaemias: role of erythropoiesis, splenectomy and transfusions. British Journal of Haematology , 176 (2) pp. 288-299. 10.1111/bjh.14373.

Porter, JB; Elalfy, M; Taher, A; Aydinok, Y; Lee, SH; Sutcharitchan, P; El-Ali, A; ... El-Beshlawy, A; + view all Porter, JB; Elalfy, M; Taher, A; Aydinok, Y; Lee, SH; Sutcharitchan, P; El-Ali, A; Han, J; El-Beshlawy, A; - view fewer (2017) Limitations of serum ferritin to predict liver iron concentration responses to deferasirox therapy in patients with transfusion-dependent thalassaemia. European Journal of Haematology , 98 (3) pp. 280-288. 10.1111/ejh.12830.

Post, M; Cuapio, A; Osl, M; Lehmann, D; Resch, U; Davies, DM; Bilban, M; ... Hofer, E; + view all Post, M; Cuapio, A; Osl, M; Lehmann, D; Resch, U; Davies, DM; Bilban, M; Schlechta, B; Eppel, W; Nathwani, A; Stoiber, D; Spanholtz, J; Casanova, E; Hofer, E; - view fewer (2017) The Transcription Factor ZnF683/hOBiT regulates human NK-cell Development. Frontiers in Immunology , 8 , Article 535. 10.3389/fimmu.2017.00535.

Powles, T; O'Donnell, PH; Massard, C; Arkenau, H-T; Friedlander, T; Hoimes, CJ; Lee, JL; ... Hahn, NM; + view all Powles, T; O'Donnell, PH; Massard, C; Arkenau, H-T; Friedlander, T; Hoimes, CJ; Lee, JL; Ong, M; Sridhar, SS; Vogelzang, NJ; Fishman, MN; Zhang, J; Srinivas, S; Parikh, J; Antal, J; Jin, X; Gupta, AK; Ben, Y; Hahn, NM; - view fewer (2017) Efficacy and Safety of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma. Updated Results From a Phase 1/2 Open-label Study. JAMA Oncology , 3 (9) , Article e172411. 10.1001/jamaoncol.2017.2411.

Presneau, N; Duhamel, LA; Ye, H; Tirabosco, R; Flanagan, AM; Eskandarpour, M; (2017) Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas. British Journal of Cancer , 117 pp. 398-408. 10.1038/bjc.2017.174.

Provenzano, L; Ryan, Y; Hilton, DA; Lyons-Rimmer, J; Dave, F; Maze, EA; Adams, CL; ... Hanemann, CO; + view all Provenzano, L; Ryan, Y; Hilton, DA; Lyons-Rimmer, J; Dave, F; Maze, EA; Adams, CL; Rigby-Jones, R; Ammoun, S; Hanemann, CO; - view fewer (2017) Cellular prion protein (PrPC) in the development of Merlin-deficient tumours. Oncogene , 36 pp. 6132-6142. 10.1038/onc.2017.200.

Pugh, G; Hough, R; Gravestock, H; Williams, K; Fisher, A; (2017) Lifestyle advice provision to teenage and young adult cancer patients: the perspective of health professionals in the UK. Support Care in Cancer , 25 (12) pp. 3823-3832. 10.1007/s00520-017-3814-5.

Pugh, G; Hough, RE; Gravestock, HL; Jackson, SE; Fisher, A; (2017) The Health Behavior Information Needs and Preferences of Teenage and Young Adult Cancer Survivors. Journal of Adolescent and Young Adult Oncology , 6 (2) pp. 318-326. 10.1089/jayao.2016.0089.

Pugh, S; Thiébaut, R; Bridgewater, J; Grisoni, ML; Moutasim, K; Rousseau, F; Thomas, GJ; ... Laurent-Puig, P; + view all Pugh, S; Thiébaut, R; Bridgewater, J; Grisoni, ML; Moutasim, K; Rousseau, F; Thomas, GJ; Griffiths, G; Liebaert, F; Primrose, J; Laurent-Puig, P; - view fewer (2017) Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: A post-hoc analysis of the New EPOC trial. Oncotarget , 8 (55) pp. 93856-93866. 10.18632/oncotarget.21291.

Pujade-Lauraine, E; Ledermann, JA; Selle, F; Gebski, V; Penson, RT; Oza, AM; Korach, J; ... SOLO2/ENGOT-Ov21 Investigators, .; + view all Pujade-Lauraine, E; Ledermann, JA; Selle, F; Gebski, V; Penson, RT; Oza, AM; Korach, J; Huzarski, T; Poveda, A; Pignata, S; Friedlander, M; Colombo, N; Harter, P; Fujiwara, K; Ray-Coquard, I; Banerjee, S; Liu, J; Lowe, ES; Bloomfield, R; Pautier, P; SOLO2/ENGOT-Ov21 Investigators, .; - view fewer (2017) Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial. The Lancet Oncology , 18 (9) pp. 1274-1284. 10.1016/S1470-2045(17)30469-2.

Qasim, W; Zhan, H; Samarasinghe, S; Adams, S; Amrolia, P; Stafford, S; Butler, K; ... Veys, P; + view all Qasim, W; Zhan, H; Samarasinghe, S; Adams, S; Amrolia, P; Stafford, S; Butler, K; Rivat, C; Wright, G; Somana, K; Ghorashian, S; Pinner, D; Ahsan, G; Gilmour, K; Lucchini, G; Inglott, S; Mifsud, W; Chiesa, R; Peggs, KS; Chan, L; Farzeneh, F; Thrasher, AJ; Vora, A; Pule, M; Veys, P; - view fewer (2017) Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells. Science Translational Medicine , 9 (374) , Article eaaj2013. 10.1126/scitranslmed.aaj2013.

Quante, M; Graham, TA; Jansen, M; (2017) Insights Into the Pathophysiology of Esophageal Adenocarcinoma. Gastroenterology , 154 (2) pp. 406-420. 10.1053/gastro.2017.09.046.

Radford, J; McKay, P; Malladi, R; Johnson, R; Bloor, A; Percival, F; Sureda, A; Radford, J; McKay, P; Malladi, R; Johnson, R; Bloor, A; Percival, F; Sureda, A; Peggs, KS; - view fewer (2017) Treatment pathways and resource use associated with recurrent Hodgkin lymphoma after autologous stem cell transplantation. Bone Marrow Transplant , 52 pp. 452-454. 10.1038/bmt.2016.244.

Rahman, S; Magnussen, M; León, TE; Farah, N; Li, Z; Abraham, BJ; Alapi, KZ; ... Mansour, MR; + view all Rahman, S; Magnussen, M; León, TE; Farah, N; Li, Z; Abraham, BJ; Alapi, KZ; Mitchell, RJ; Naughton, T; Fielding, AK; Pizzey, A; Bustraan, S; Allen, C; Popa, T; Pike-Overzet, K; Garcia-Perez, L; Gale, RE; Linch, DC; Staal, FJT; Young, RA; Look, AT; Mansour, MR; - view fewer (2017) Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia. Blood , 129 (24) pp. 3221-3226. 10.1182/blood-2016-09-742148.

Raine, R; Atkin, W; Von Wagner, C; Duffy, S; Kralj-Hans, I; Hackshaw, A; Counsell, N; ... Wardle, J; + view all Raine, R; Atkin, W; Von Wagner, C; Duffy, S; Kralj-Hans, I; Hackshaw, A; Counsell, N; Moss, S; McGregor, L; Palmer, C; Smith, SG; Thomas, M; Howe, R; Vart, G; Band, R; Halloran, SP; Snowball, J; Stubbs, N; Handley, G; Logan, R; Rainbow, S; Obichere, A; Smith, S; Morris, S; Solmi, F; Wardle, J; - view fewer (2017) Testing innovative strategies to reduce the social gradient in the uptake of bowel cancer screening: a programme of four qualitatively enhanced randomised controlled trial. Programme Grants for Applied Research , 5 (8) 10.3310/pgfar05080.

Read, ML; Fong, JC; Modasia, B; Fletcher, A; Imruetaicharoenchoke, W; Thompson, RJ; Nieto, H; ... McCabe, CJ; + view all Read, ML; Fong, JC; Modasia, B; Fletcher, A; Imruetaicharoenchoke, W; Thompson, RJ; Nieto, H; Reynolds, JJ; Bacon, A; Mallick, U; Hackshaw, A; Watkinson, JC; Boelaert, K; Turnell, AS; Smith, VE; McCabe, CJ; - view fewer (2017) Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer. Oncogene , 36 (37) pp. 5296-5308. 10.1038/onc.2017.154.

Reardon, PJT; Parhizkar, M; Harker, AH; Browning, RJ; Vassileva, V; Stride, E; Pedley, RB; ... Knowles, JC; + view all Reardon, PJT; Parhizkar, M; Harker, AH; Browning, RJ; Vassileva, V; Stride, E; Pedley, RB; Edirisinghe, M; Knowles, JC; - view fewer (2017) Electrohydrodynamic fabrication of core-shell PLGA nanoparticles with controlled release of cisplatin for enhanced cancer treatment. International Journal of Nanomedicine , 12 pp. 3913-3926. 10.2147/IJN.S134833.

Reuter, M; Camus, MF; Hill, MS; Ruzicka, F; Fowler, K; (2017) Evolving Plastic Responses to External and Genetic Environments. Trends in Genetics , 33 (3) pp. 169-170. 10.1016/j.tig.2017.01.004.

Robinson, E; Nunes, JPM; Vassileva, V; Maruani, A; Nogueira, JCF; Smith, MEB; Pedley, RB; ... Chudasama, V; + view all Robinson, E; Nunes, JPM; Vassileva, V; Maruani, A; Nogueira, JCF; Smith, MEB; Pedley, RB; Caddick, S; Baker, JR; Chudasama, V; - view fewer (2017) Pyridazinediones deliver potent, stable, targeted and efficacious antibody–drug conjugates (ADCs) with a controlled loading of 4 drugs per antibody. RSC Advances , 7 (15) pp. 9073-9077. 10.1039/C7RA00788D.

Robinson, J; Guethlein, LA; Cereb, N; Yang, SY; Norman, PJ; Marsh, SGE; Parham, P; (2017) Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles. PLoS Genetics , 13 (6) , Article e1006862. 10.1371/journal.pgen.1006862.

Roddie, C; Peggs, KS; (2017) Immunotherapy for transplantation-associated viral infections. Journal Of Clinical Investigation , 127 (7) pp. 2513-2522. 10.1172/JCI90599.

Roncolato, FT; Joly, F; O'Connell, R; Lanceley, A; Hilpert, F; Buizen, L; Okamoto, A; ... Friedlander, M; + view all Roncolato, FT; Joly, F; O'Connell, R; Lanceley, A; Hilpert, F; Buizen, L; Okamoto, A; Aotani, E; Pignata, S; Donnellan, P; Oza, A; Avall-Lundqvist, E; Berek, JS; Heitz, F; Feeney, A; Berton-Rigaud, D; Stockler, MR; King, M; Friedlander, M; - view fewer (2017) Reducing Uncertainty: Predictors of Stopping Chemotherapy Early and Shortened Survival Time in Platinum Resistant/Refractory Ovarian Cancer-The GCIG Symptom Benefit Study. The Oncologist , 22 (9) pp. 1117-1124. 10.1634/theoncologist.2017-0047.

Rosenthal, R; McGranahan, N; Herrero, J; Swanton, C; (2017) Deciphering Genetic Intratumor Heterogeneity and Its Impact on Cancer Evolution. Annual Review of Cancer Biology , 1 pp. 223-240. 10.1146/annurev-cancerbio-042516-011348.

Rossello, X; Riquelme, JA; He, Z; Taferner, S; Vanhaesebroeck, B; Davidson, SM; Yellon, DM; (2017) The role of PI3Kα isoform in cardioprotection. Basic Research in Cardiology , 112 , Article 66. 10.1007/s00395-017-0657-7.

Rossig, C; Pule, M; Altvater, B; Saiagh, S; Wright, G; Ghorashian, S; Clifton-Hadley, L; ... Amrolia, PJ; + view all Rossig, C; Pule, M; Altvater, B; Saiagh, S; Wright, G; Ghorashian, S; Clifton-Hadley, L; Champion, K; Sattar, Z; Popova, B; Hackshaw, A; Smith, P; Roberts, T; Biagi, E; Dreno, B; Rousseau, R; Kailayangiri, S; Ahlmann, M; Hough, R; Kremens, B; Sauer, MG; Veys, P; Goulden, N; Cummins, M; Amrolia, PJ; - view fewer (2017) Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia. Leukemia , 31 pp. 1087-1095. 10.1038/leu.2017.39.

Ruers, T; Van Coevorden, F; Punt, CJA; Pierie, J-PEN; Borel-Rinkes, I; Ledermann, JA; Poston, G; ... and the National Cancer Research Institute Colorectal Clinical S, .; + view all Ruers, T; Van Coevorden, F; Punt, CJA; Pierie, J-PEN; Borel-Rinkes, I; Ledermann, JA; Poston, G; Bechstein, W; Lentz, M-A; Mauer, M; Folprecht, G; Van Cutsem, E; Ducreux, M; Nordlinger, B; European Organisation for Research and Treatment of Cancer (EORT, .; Gastro-Intestinal Tract Cancer Group, .; Arbeitsgruppe Lebermetastasen und tumoren in der Chirurgischen A, .; and the National Cancer Research Institute Colorectal Clinical S, .; - view fewer (2017) Local Treatment of Unresectable Colorectal Liver Metastases: Results of a Randomized Phase II Trial. JNCI: Journal of the National Cancer Institute , 109 (9) , Article djx015. 10.1093/jnci/djx015.

Russell, LJ; Jones, L; Enshaei, A; Tonin, S; Ryan, SL; Eswaran, J; Nakjang, S; ... Harrison, CJ; + view all Russell, LJ; Jones, L; Enshaei, A; Tonin, S; Ryan, SL; Eswaran, J; Nakjang, S; Papaemmanuil, E; Tubio, JMC; Fielding, AK; Vora, A; Campbell, PJ; Moorman, AV; Harrison, CJ; - view fewer (2017) Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia. Genes, Chromosomes and Cancer , 56 (5) pp. 363-372. 10.1002/gcc.22439.

Sangro, B; Martínez-Urbistondo, D; Bester, L; Bilbao, JI; Coldwell, DM; Flamen, P; Kennedy, A; ... Sharma, RA; + view all Sangro, B; Martínez-Urbistondo, D; Bester, L; Bilbao, JI; Coldwell, DM; Flamen, P; Kennedy, A; Ricke, J; Sharma, RA; - view fewer (2017) Prevention and treatment of complications of selective internal radiation therapy: expert guidance and systematic review. Hepatology , 66 (3) pp. 969-982. 10.1002/hep.29207.

Sansregret, L; Patterson, JO; Dewhurst, S; Lopez-Garcia, C; Koch, A; McGranahan, N; Chao, WCH; ... Swanton, C; + view all Sansregret, L; Patterson, JO; Dewhurst, S; Lopez-Garcia, C; Koch, A; McGranahan, N; Chao, WCH; Barry, DJ; Rowan, A; Instrell, R; Horswell, S; Way, M; Howell, M; Singleton, MR; Medema, RH; Nurse, P; Petronczki, M; Swanton, C; - view fewer (2017) APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. Cancer Discovery , 7 (2) pp. 218-233. 10.1158/2159-8290.CD-16-0645.

Sansregret, L; Swanton, C; (2017) The Role of Aneuploidy in Cancer Evolution. Cold Spring Harbor Perspectives in Medicine , 7 (1) , Article a028373. 10.1101/cshperspect.a028373.

Schiffmann, R; Hughes, DA; Linthorst, GE; Ortiz, A; Svarstad, E; Warnock, DG; West, ML; Schiffmann, R; Hughes, DA; Linthorst, GE; Ortiz, A; Svarstad, E; Warnock, DG; West, ML; Wanner, C; - view fewer (2017) Screening, diagnosis, and management of patients with Fabry disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference. Kidney International , 91 (2) pp. 284-293. 10.1016/j.kint.2016.10.004.

Schöffski, P; Wozniak, A; Casali, PG; Rutkowski, P; Blay, J-Y; Lindner, LH; Strauss, SJ; ... Bauer, S; + view all Schöffski, P; Wozniak, A; Casali, PG; Rutkowski, P; Blay, J-Y; Lindner, LH; Strauss, SJ; Anthoney, A; Duffaud, F; Richter, S; Grünwald, V; Leahy, MG; Reichardt, P; Sufliarsky, J; van der Graaf, WT; Sciot, R; Debiec-Rychter, M; van Cann, T; Marréaud, S; Lia, M; Raveloarivahy, T; Collette, L; Bauer, S; - view fewer (2017) Activity and safety of crizotinib in patients with advanced clear cell sarcoma with MET alterations. European Organization for Research and Treatment of Cancer phase 2 trial 90101 "CREATE". Annals of Oncology , 28 (12) pp. 3000-3008. 10.1093/annonc/mdx527.

Schöneberg, J; Lehmann, M; Ullrich, A; Posor, Y; Lo, W-T; Lichtner, G; Schmoranzer, J; ... Noé, F; + view all Schöneberg, J; Lehmann, M; Ullrich, A; Posor, Y; Lo, W-T; Lichtner, G; Schmoranzer, J; Haucke, V; Noé, F; - view fewer (2017) Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission. Nature Communications , 8 , Article 15873. 10.1038/ncomms15873.

Schoser, B; Fong, E; Geberhiwot, T; Hughes, D; Kissel, JT; Madathil, SC; Orlikowski, D; ... Young, P; + view all Schoser, B; Fong, E; Geberhiwot, T; Hughes, D; Kissel, JT; Madathil, SC; Orlikowski, D; Polkey, MI; Roberts, M; Tiddens, HAWM; Young, P; - view fewer (2017) Maximum inspiratory pressure as a clinically meaningful trial endpoint for neuromuscular diseases: a comprehensive review of the literature. [Review]. Orphanet Journal of Rare Diseases , 12 , Article 52. 10.1186/s13023-017-0598-0.

Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; ... Yaspo, ML; + view all Schütte, M; Risch, T; Abdavi-Azar, N; Boehnke, K; Schumacher, D; Keil, M; Yildiriman, R; Jandrasits, C; Borodina, T; Amstislavskiy, V; Worth, CL; Schweiger, C; Liebs, S; Lange, M; Warnatz, HJ; Butcher, LM; Barrett, JE; Sultan, M; Wierling, C; Golob-Schwarzl, N; Lax, S; Uranitsch, S; Becker, M; Welte, Y; Regan, JL; Silvestrov, M; Kehler, I; Fusi, A; Kessler, T; Herwig, R; Landegren, U; Wienke, D; Nilsson, M; Velasco, JA; Garin-Chesa, P; Reinhard, C; Beck, S; Schäfer, R; Regenbrecht, CR; Henderson, D; Lange, B; Haybaeck, J; Keilholz, U; Hoffmann, J; Lehrach, H; Yaspo, ML; - view fewer (2017) Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors. Nature Communications , 8 , Article 14262. 10.1038/ncomms14262.

Seckl, MJ; Ottensmeier, CH; Cullen, M; Schmid, P; Ngai, Y; Muthukumar, D; Thompson, J; ... Hackshaw, A; + view all Seckl, MJ; Ottensmeier, CH; Cullen, M; Schmid, P; Ngai, Y; Muthukumar, D; Thompson, J; Harden, S; Middleton, G; Fife, KM; Crosse, B; Taylor, P; Nash, S; Hackshaw, A; - view fewer (2017) Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR). Journal of Clincal Oncology , Article 2016697391. 10.1200/JCO.2016.69.7391.

Seddon, B; Strauss, SJ; Whelan, J; Leahy, M; Woll, PJ; Cowie, F; Rothermundt, C; ... Beare, S; + view all Seddon, B; Strauss, SJ; Whelan, J; Leahy, M; Woll, PJ; Cowie, F; Rothermundt, C; Wood, Z; Benson, C; Ali, N; Marples, M; Veal, GJ; Jamieson, D; Küver, K; Tirabosco, R; Forsyth, S; Nash, S; Dehbi, H-M; Beare, S; - view fewer (2017) Gemcitabine and docetaxel versus doxorubicin as first-line treatment in previously untreated advanced unresectable or metastatic soft-tissue sarcomas (GeDDiS): a randomised controlled phase 3 trial. The Lancet Oncology , 18 (10) pp. 1397-1410. 10.1016/S1470-2045(17)30622-8.

Serbanovic-Canic, J; de Luca, A; Warboys, C; Ferreira, PF; Luong, LA; Hsiao, S; Gauci, I; ... Evans, PC; + view all Serbanovic-Canic, J; de Luca, A; Warboys, C; Ferreira, PF; Luong, LA; Hsiao, S; Gauci, I; Mahmoud, M; Feng, S; Souilhol, C; Bowden, N; Ashton, J-P; Walczak, H; Firmin, D; Krams, R; Mason, JC; Haskard, DO; Sherwin, S; Ridger, V; Chico, TJA; Evans, PC; - view fewer (2017) Zebrafish Model for Functional Screening of Flow-Responsive Genes. Arteriosclerosis, Thrombosis and Vascular Biology , 37 (1) pp. 130-143. 10.1161/ATVBAHA.116.308502.

Shafat, MS; Oellerich, T; Mohr, S; Robinson, SD; Edwards, DR; Marlein, CR; Piddock, RE; ... Rushworth, SA; + view all Shafat, MS; Oellerich, T; Mohr, S; Robinson, SD; Edwards, DR; Marlein, CR; Piddock, RE; Fenech, M; Zaitseva, L; Abdul-Aziz, A; Turner, J; Watkins, JA; Lawes, M; Bowles, KM; Rushworth, SA; - view fewer (2017) Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment. Blood , 129 (10) pp. 1320-1332. 10.1182/blood-2016-08-734798.

Shankar, AG; Roques, G; Kirkwood, AA; Lambilliotte, A; Freund, K; Leblanc, T; Hayward, J; ... Landman-Parker, J; + view all Shankar, AG; Roques, G; Kirkwood, AA; Lambilliotte, A; Freund, K; Leblanc, T; Hayward, J; Abbou, S; Ramsay, AD; Schmitt, C; Gorde-Grosjean, S; Pacquement, H; Haouy, S; Boudjemaa, S; Aladjidi, N; Hall, GW; Landman-Parker, J; - view fewer (2017) Advanced stage nodular lymphocyte predominant Hodgkin lymphoma in children and adolescents: clinical characteristics and treatment outcome - a report from the SFCE & CCLG groups. British Journal of Haematology , 177 (1) pp. 106-115. 10.1111/bjh.14518.

Shaw, BE; Mayor, NP; Szydlo, RM; Bultitude, WP; Anthias, C; Kirkland, K; Perry, J; ... Marsh, SG; + view all Shaw, BE; Mayor, NP; Szydlo, RM; Bultitude, WP; Anthias, C; Kirkland, K; Perry, J; Clark, A; Mackinnon, S; Marks, DI; Pagliuca, A; Potter, MN; Russell, NH; Thomson, K; Madrigal, JA; Marsh, SG; - view fewer (2017) Recipient/donor HLA and CMV matching in recipients of T-cell-depleted unrelated donor haematopoietic cell transplants. Bone Marrow Transplant , 52 pp. 717-725. 10.1038/bmt.2016.352.

Shaw, L; Ribeiro, ALR; Levine, AP; Pontikos, N; Balloux, F; Segal, AW; Roberts, AP; Shaw, L; Ribeiro, ALR; Levine, AP; Pontikos, N; Balloux, F; Segal, AW; Roberts, AP; Smith, AM; - view fewer (2017) The Human Salivary Microbiome Is Shaped by Shared Environment Rather than Genetics: Evidence from a Large Family of Closely Related Individuals. MBio , 8 (5) , Article e01237-17. 10.1128/mBio.01237-17.

Shimizu, Y; Peltzer, N; Sevko, A; Lafont, E; Sarr, A; Draberova, H; Walczak, H; (2017) The linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis. Hepatology , 65 (6) pp. 1963-1978. 10.1002/hep.29074.

Siddharthan, T; Grigsby, M; Miele, CH; Bernabe-Ortiz, A; Miranda, JJ; Gilman, RH; Wise, RA; ... Checkley, W; + view all Siddharthan, T; Grigsby, M; Miele, CH; Bernabe-Ortiz, A; Miranda, JJ; Gilman, RH; Wise, RA; Porter, JC; Hurst, JR; Checkley, W; - view fewer (2017) Prevalence and risk factors of restrictive spirometry in a cohort of Peruvian adults. The International Journal of Tuberculosis and Lung Disease , 21 (9) pp. 1062-1068. 10.5588/ijtld.17.0101.

Singer, R; Campbell, P; Fernandes, C; Statham, P; Hochhauser, D; Bridgewater, J; (2017) Time to endoscopic intervention in patients with upper gastrointestinal patients can be improved with pathway provision. BMC Cancer , 17 , Article 365. 10.1186/s12885-017-3335-0.

Singh, A; Mishra, A; Khosravi, A; Khandelwal, G; Jayaram, B; (2017) Physico-chemical fingerprinting of RNA genes. Nucleic Acids Research , 45 (7) , Article e47. 10.1093/nar/gkw1236.

Singh, HD; Otano, I; Rombouts, K; Singh, KP; Peppa, D; Gill, US; Bottcher, K; ... Maini, MK; + view all Singh, HD; Otano, I; Rombouts, K; Singh, KP; Peppa, D; Gill, US; Bottcher, K; Kennedy, PTF; Oben, J; Pinzani, M; Walczak, H; Fusai, G; Rosenberg, WMC; Maini, MK; - view fewer (2017) TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis. Scientific Reports , 7 , Article 5514. 10.1038/s41598-017-05845-5.

Skalska, L; Beltran-Nebot, M; Ule, J; Jenner, RG; (2017) Regulatory feedback from nascent RNA to chromatin and transcription. Nature Reviews Molecular Cell Biology , 18 (5) pp. 331-337. 10.1038/nrm.2017.12.

Smith, SG; Wardle, J; Atkin, W; Raine, R; McGregor, L; Vart, G; Morris, S; ... von Wagner, C; + view all Smith, SG; Wardle, J; Atkin, W; Raine, R; McGregor, L; Vart, G; Morris, S; Duffy, SW; Moss, S; Hackshaw, A; Halloran, S; Kralj-Hans, I; Howe, R; Snowball, J; Handley, G; Logan, RF; Rainbow, S; Smith, S; Thomas, M; Counsell, N; von Wagner, C; - view fewer (2017) Reducing the socioeconomic gradient in uptake of the NHS Bowel Cancer Screening Programme using a simplified supplementary information leaflet: a cluster-randomised trial. BMC Cancer , 17 , Article 543. 10.1186/s12885-017-3512-1.

Snowden, JA; Greenfield, DM; Bird, JM; Boland, E; Bowcock, S; Fisher, A; Low, E; ... UK Myeloma Forum (UKMF) and the British Society for Haematology, .; + view all Snowden, JA; Greenfield, DM; Bird, JM; Boland, E; Bowcock, S; Fisher, A; Low, E; Morris, M; Yong, K; Pratt, G; UK Myeloma Forum (UKMF) and the British Society for Haematology, .; - view fewer (2017) Guidelines for screening and management of late and long-term consequences of myeloma and its treatment. British Journal of Haematology , 176 (6) pp. 888-907. 10.1111/bjh.14514.

Soderquest, K; Hertweck, A; Giambartolomei, C; Henderson, S; Mohamed, R; Goldberg, R; Perucha, E; ... Lord, GM; + view all Soderquest, K; Hertweck, A; Giambartolomei, C; Henderson, S; Mohamed, R; Goldberg, R; Perucha, E; Franke, L; Herrero, J; Plagnol, V; Jenner, RG; Lord, GM; - view fewer (2017) Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease. PLOS GENETICS , 13 (2) 10.1371/journal.pgen.1006587.

Spicer, J; Irshad, S; Ang, JE; Enting, D; Kristeleit, RS; Uttenreuther-Fischer, M; Pemberton, K; ... De Bono, J; + view all Spicer, J; Irshad, S; Ang, JE; Enting, D; Kristeleit, RS; Uttenreuther-Fischer, M; Pemberton, K; Pelling, K; Schnell, D; De Bono, J; - view fewer (2017) A phase I study of afatinib combined with paclitaxel and bevacizumab in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology , 79 (1) pp. 17-27. 10.1007/s00280-016-3189-1.

Stacchiotti, S; Gronchi, A; Fossati, P; Akiyama, T; Alapetite, C; Baumann, M; Blay, JY; ... Sommer, J; + view all Stacchiotti, S; Gronchi, A; Fossati, P; Akiyama, T; Alapetite, C; Baumann, M; Blay, JY; Bolle, S; Boriani, S; Bruzzi, P; Capanna, R; Caraceni, A; Casadei, R; Colia, V; Debus, J; Delaney, T; Desai, A; Dileo, P; Dijkstra, S; Doglietto, F; Flanagan, A; Froelich, S; Gardner, PA; Gelderblom, H; Gokaslan, ZL; Haas, R; Heery, C; Hindi, N; Hohenberger, P; Hornicek, F; Imai, R; Jeys, L; Jones, RL; Kasper, B; Kawai, A; Krengli, M; Leithner, A; Logowska, I; Martin Broto, J; Mazzatenta, D; Morosi, C; Nicolai, P; Norum, OJ; Patel, S; Penel, N; Picci, P; Pilotti, S; Radaelli, S; Ricchini, F; Rutkowski, P; Scheipl, S; Sen, C; Tamborini, E; Thornton, KA; Timmermann, B; Torri, V; Tunn, PU; Uhl, M; Yamada, Y; Weber, DC; Vanel, D; Varga, PP; Vleggeert-Lankamp, CLA; Casali, PG; Sommer, J; - view fewer (2017) Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group. Annals of Oncology , 28 (6) pp. 1230-1242. 10.1093/annonc/mdx054.

Stahl, T; Bofinger, R; Lam, I; Fallon, KJ; Johnson, P; Ogunlade, O; Vassileva, V; ... Tabor, AB; + view all Stahl, T; Bofinger, R; Lam, I; Fallon, KJ; Johnson, P; Ogunlade, O; Vassileva, V; Pedley, RB; Beard, PC; Hailes, HC; Bronstein, H; Tabor, AB; - view fewer (2017) Tunable Semiconducting Polymer Nanoparticles with INDT-Based Conjugated Polymers for Photoacoustic Molecular Imaging. Bioconjugate Chemistry , 28 (6) pp. 1734-1740. 10.1021/acs.bioconjchem.7b00185.

Stark, D; Cook, A; Brown, J; Brundage, M; Embleton, A; Kaplan, R; Raja, F; ... Ledermann, J; + view all Stark, D; Cook, A; Brown, J; Brundage, M; Embleton, A; Kaplan, R; Raja, F; Swart, AM; Velikova, G; Qian, W; Ledermann, J; - view fewer (2017) Quality of life with cediranib in relapsed ovarian cancer: The ICON6 phase 3 randomized clinical trial. Cancer , 123 (14) pp. 2752-2761. 10.1002/cncr.30657.

Stathopoulou, A; Chhetri, JB; Ambrose, JC; Estève, P-O; Ji, L; Erdjument-Bromage, H; Zhang, G; ... Ooi, SKT; + view all Stathopoulou, A; Chhetri, JB; Ambrose, JC; Estève, P-O; Ji, L; Erdjument-Bromage, H; Zhang, G; Neubert, TA; Pradhan, S; Herrero, J; Schmitz, RJ; Ooi, SKT; - view fewer (2017) A novel requirement for DROSHA in maintenance of mammalian CG methylation. Nucleic Acids Research , 45 (16) pp. 9398-9412. 10.1093/nar/gkx695.

Stathopoulou, A; Chhetri, JB; Ambrose, JC; Estève, P-O; Ji, L; Erdjument-Bromage, H; Zhang, G; ... Ooi, SKT; + view all Stathopoulou, A; Chhetri, JB; Ambrose, JC; Estève, P-O; Ji, L; Erdjument-Bromage, H; Zhang, G; Neubert, TA; Pradhan, S; Herrero, J; Schmitz, RJ; Ooi, SKT; - view fewer (2017) A novel requirement for DROSHA in maintenance of mammalian CG methylation. [Corrigendum]. Nucleic Acids Research , 45 (16) p. 9810. 10.1093/nar/gkx736.

Stockwell, SR; Mittnacht, S; (2017) High-Content Imaging and RNAi Screens for Investigating Kinase Network Plasticity. Kinase Signaling Networks , 1636 pp. 133-161. 10.1007/978-1-4939-7154-1_10.

Stricker, SH; Koferle, A; Beck, S; (2017) From profiles to function in epigenomics. [Review]. Nature Reviews Genetics , 18 (1) pp. 51-66. 10.1038/nrg.2016.138.

Suh, Y-E; Lawler, K; Henley-Smith, R; Pike, L; Leek, R; Barrington, S; Odell, EW; ... Tavassoli, M; + view all Suh, Y-E; Lawler, K; Henley-Smith, R; Pike, L; Leek, R; Barrington, S; Odell, EW; Ng, T; Pezzella, F; Guerrero-Urbano, T; Tavassoli, M; - view fewer (2017) Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma. British Journal of Cancer , 116 (8) pp. 1057-1064. 10.1038/bjc.2017.66.

Sun, Y; Best, K; Cinelli, M; Heather, JM; Reich-Zeliger, S; Shifrut, E; Friedman, N; ... Chain, B; + view all Sun, Y; Best, K; Cinelli, M; Heather, JM; Reich-Zeliger, S; Shifrut, E; Friedman, N; Shawe-Taylor, J; Chain, B; - view fewer (2017) Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization. Front Immunol , 8 , Article 430. 10.3389/fimmu.2017.00430.

Swisher, E; Harrell, MI; Lin, KK; Scott, CL; Goble, S; Oza, A; Coleman, RL; ... Kaufmann, S; + view all Swisher, E; Harrell, MI; Lin, KK; Scott, CL; Goble, S; Oza, A; Coleman, RL; Konecny, G; Tinker, AV; O'Malley, DM; Kristeleit, RS; Ma, L; Brenton, J; Bell-McGuinn, K; Oaknin, A; Leary, A; Mann, E; Giordano, H; Raponi, M; McNeish, I; Kaufmann, S; - view fewer (2017) BRCA1 and RAD51C Promoter Hypermethylation Confer Sensitivity to PARP Inhibitors in Patients with Platinum Sensitive Ovarian Carcinoma. Clinical Cancer Research , 23 (11 Suppl) 10.1158/1557-3265.OVCASYMP16-AP28.

Swisher, EM; Lin, KK; Oza, AM; Scott, CL; Giordano, H; Sun, J; Konecny, GE; ... McNeish, IA; + view all Swisher, EM; Lin, KK; Oza, AM; Scott, CL; Giordano, H; Sun, J; Konecny, GE; Coleman, RL; Tinker, AV; O'Malley, DM; Kristeleit, RS; Ma, L; Bell-McGuinn, KM; Brenton, JD; Cragun, JM; Oaknin, A; Ray-Coquard, I; Harrell, MI; Mann, E; Kaufmann, SH; Floquet, A; Leary, A; Harding, TC; Goble, S; Maloney, L; Isaacson, J; Allen, AR; Rolfe, L; Yelensky, R; Raponi, M; McNeish, IA; - view fewer (2017) Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial. Lancet Oncology , 18 (1) pp. 75-87. 10.1016/S1470-2045(16)30559-9.

Szlosarek, PW; Steele, JP; Nolan, L; Gilligan, D; Taylor, P; Spicer, J; Lind, M; ... Hackshaw, A; + view all Szlosarek, PW; Steele, JP; Nolan, L; Gilligan, D; Taylor, P; Spicer, J; Lind, M; Mitra, S; Shamash, J; Phillips, MM; Luong, P; Payne, S; Hillman, P; Ellis, S; Szyszko, T; Dancey, G; Butcher, L; Beck, S; Avril, NE; Thomson, J; Johnston, A; Tomsa, M; Lawrence, C; Schmid, P; Crook, T; Wu, B-W; Bomalaski, JS; Lemoine, N; Sheaff, MT; Rudd, RM; Fennell, D; Hackshaw, A; - view fewer (2017) Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma A Randomized Clinical Trial. JAMA Oncology , 3 (1) pp. 58-66. 10.1001/jamaoncol.2016.3049.

Taher, AT; Origa, R; Perrotta, S; Kourakli, A; Ruffo, GB; Kattamis, A; Goh, AS; ... Porter, JB; + view all Taher, AT; Origa, R; Perrotta, S; Kourakli, A; Ruffo, GB; Kattamis, A; Goh, AS; Cortoos, A; Huang, V; Weill, M; Merino Herranz, R; Porter, JB; - view fewer (2017) New film-coated tablet formulation of deferasirox is well tolerated in patients with thalassemia or lower-risk MDS: Results of the randomized, phase II ECLIPSE study. American Journal of Hematology , 92 (5) pp. 420-428. 10.1002/ajh.24668.

Taieb, J; Kourie, HR; Emile, J-F; Le Malicot, K; Balogoun, R; Tabernero, J; Mini, E; ... Pan-European Trials in Alimentary Tract Cancer (PETACC)-8 Invest; + view all Taieb, J; Kourie, HR; Emile, J-F; Le Malicot, K; Balogoun, R; Tabernero, J; Mini, E; Folprecht, G; Van Laethem, J-L; Mulot, C; Bouché, O; Aparicio, T; Michel, P; Thaler, J; Bridgewater, J; Van Cutsem, E; Perkins, G; Lepage, C; Salazar, R; Laurent-Puig, P; Pan-European Trials in Alimentary Tract Cancer (PETACC)-8 Invest; - view fewer (2017) Association of Prognostic Value of Primary Tumor Location in Stage III Colon Cancer With RAS and BRAF Mutational Status. JAMA Oncology 10.1001/jamaoncol.2017.3695. (In press).

Tailor, H; Mackie, I; Mellick, A; Machin, S; (2017) Evaluation of the Sysmex XN-550, a Novel Compact Haematology analyser from the XN-L (R) series, compared to the XN-20 system. International Journal of Laboratory Hematology , 39 (6) pp. 585-589. 10.1111/ijlh.12701.

Tan, WS; Feber, A; Dong, L; Sarpong, R; Rezaee, S; Rodney, S; Khetrapal, P; ... Kelly, JD; + view all Tan, WS; Feber, A; Dong, L; Sarpong, R; Rezaee, S; Rodney, S; Khetrapal, P; de Winter, P; Ocampo, F; Jalil, R; Williams, NR; Brew-Graves, C; Kelly, JD; - view fewer (2017) DETECT I & DETECT II: a study protocol for a prospective multicentre observational study to validate the UroMark assay for the detection of bladder cancer from urinary cells. BMC Cancer , 17 , Article 767. 10.1186/s12885-017-3758-7.

Tanic, M; Beck, S; (2017) Cell-free DNA: Treasure trove for cancer medicine. Nature Materials , 16 (11) pp. 1056-1057. 10.1038/nmat5019.

Tanic, M; Beck, S; (2017) Epigenome-wide association studies for cancer biomarker discovery in circulating cell-free DNA: technical advances and challenges. Current Opinion in Genetics and Development , 42 pp. 48-55. 10.1016/j.gde.2017.01.017.

Tape, CJ; (2017) The Heterocellular Emergence of Colorectal Cancer. Trends Cancer , 3 (2) pp. 79-88. 10.1016/j.trecan.2016.12.004.

Tarpey, PS; Behjati, S; Young, MD; Martincorena, I; Alexandrov, LB; Farndon, SJ; Guzzo, C; ... Campbell, PJ; + view all Tarpey, PS; Behjati, S; Young, MD; Martincorena, I; Alexandrov, LB; Farndon, SJ; Guzzo, C; Hardy, C; Latimer, C; Butler, AP; Teague, JW; Shlien, A; Futreal, PA; Shah, S; Bashashati, A; Jamshidi, F; Nielsen, TO; Huntsman, D; Baumhoer, D; Brandner, S; Wunder, J; Dickson, B; Cogswell, P; Sommer, J; Phillips, JJ; Amary, MF; Tirabosco, R; Pillay, N; Yip, S; Stratton, MR; Flanagan, AM; Campbell, PJ; - view fewer (2017) The driver landscape of sporadic chordoma. Nature Communications , 8 , Article 890. 10.1038/s41467-017-01026-0.

Taylor, RM; Aslam, N; Lea, S; Whelan, JS; Fern, LA; (2017) Optimizing a Retention Strategy with Young People for BRIGHTLIGHT, a Longitudinal Cohort Study Examining the Value of Specialist Cancer Care for Young People. Journal of Adolescent and Young Adult Oncology , 6 (3) pp. 459-469. 10.1089/jayao.2016.0085.

Taylor, SA; Mallett, S; Miles, A; Beare, S; Bhatnagar, G; Bridgewater, J; Glynne-Jones, R; ... Halligan, S; + view all Taylor, SA; Mallett, S; Miles, A; Beare, S; Bhatnagar, G; Bridgewater, J; Glynne-Jones, R; Goh, V; Groves, AM; Janes, SM; Koh, DM; Morris, S; Morton, A; Navani, N; Oliver, A; Padhani, AR; Punwani, S; Rockall, AG; Halligan, S; - view fewer (2017) Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L). BMC Cancer , 17 , Article 299. 10.1186/s12885-017-3281-x.

Teschendorff, AE; Breeze, CE; Zheng, SC; Beck, S; (2017) A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies. BMC Bioinformatics , 18 (1) , Article 105. 10.1186/s12859-017-1511-5.

Teschendorff, AE; Enver, T; (2017) Single-cell entropy for accurate estimation of differentiation potency from a cell's transcriptome. Nature Communications , 8 , Article 15599. 10.1038/ncomms15599.

Tesson, Mathias; Rae, Colin; L Nile, Donna; N Gaze, Mark; J. Mairs, Robert; (2017) Targeted radiotherapy of neuroblastoma: Future directions. Integrative Cancer Science and Therapeutics , 4 (5) pp. 1-2. 10.15761/icst.1000260.

Thistlethwaite, FC; Gilham, DE; Guest, RD; Rothwell, DG; Pillai, M; Burt, DJ; Byatte, AJ; ... Hawkins, RE; + view all Thistlethwaite, FC; Gilham, DE; Guest, RD; Rothwell, DG; Pillai, M; Burt, DJ; Byatte, AJ; Kirillova, N; Valle, JW; Sharma, SK; Chester, KA; Westwood, NB; Halford, SER; Nabarro, S; Wan, S; Austin, E; Hawkins, RE; - view fewer (2017) The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity. Cancer Immunology, Immunotherapy 10.1007/s00262-017-2034-7. (In press).

Tian, Y; Morris, TJ; Webster, AP; Yang, Z; Beck, S; Feber, A; Teschendorff, AE; (2017) ChAMP: Updated Methylation Analysis Pipeline for Illumina BeadChips. Bioinformatics , 33 (24) pp. 3982-3984. 10.1093/bioinformatics/btx513.

Tomas, A; Jones, S; Vaughan, SO; Hochhauser, D; Futter, CE; (2017) Stress-specific p38 MAP kinase activation is sufficient to drive EGF receptor endocytosis but not nuclear translocation. Journal of Cell Science , 130 (15) pp. 2481-2490. 10.1242/jcs.202358.

Tostoes, R; Dodgson, J; Weil, B; Gerontas, S; Mason, C; Veraitch, FS; (2017) A novel filtration system for point of care washing of cellular therapy products. Journal of Tissue Engineering and Regenerative Medicine , 11 (11) pp. 3157-3167. 10.1002/term.2225.

Tuddenham, EG; (2017) Platelets are a safe way to deliver factor VIII. After 13 years of preclinical research it is now time for a clinical trial. Journal of Thrombosis and Haemostasis , 15 (1) pp. 96-97. 10.1111/jth.13545.

Turajlic, S; Litchfield, K; Xu, H; Rosenthal, R; McGranahan, N; Reading, JL; Wong, YNS; ... Swanton, C; + view all Turajlic, S; Litchfield, K; Xu, H; Rosenthal, R; McGranahan, N; Reading, JL; Wong, YNS; Rowan, A; Kanu, N; Al Bakir, M; Chambers, T; Salgado, R; Savas, P; Loi, S; Birkbak, NJ; Sansregret, L; Gore, M; Larkin, J; Quezada, SA; Swanton, C; - view fewer (2017) Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis. The Lancet Oncology , 18 (8) pp. 1009-1021. 10.1016/S1470-2045(17)30516-8.

Valet, C; Levade, M; Chicanne, G; Bilanges, B; Cabou, C; Viaud, J; Gratacap, M-P; ... Severin, S; + view all Valet, C; Levade, M; Chicanne, G; Bilanges, B; Cabou, C; Viaud, J; Gratacap, M-P; Gaits-Iacovoni, F; Vanhaesebroeck, B; Payrastre, B; Severin, S; - view fewer (2017) A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth. Blood , 130 (18) pp. 2032-2042. 10.1182/blood-2017-04-781641.

Vargas, FA; Furness, AJS; Solomon, I; Joshi, K; Mekkaoui, L; Lesko, MH; Rota, EM; ... Quezada, SA; + view all Vargas, FA; Furness, AJS; Solomon, I; Joshi, K; Mekkaoui, L; Lesko, MH; Rota, EM; Dahan, R; Georgiou, A; Sledzinska, A; Ben Aissa, A; Franz, D; Sunderland, MW; Wong, YNS; Henry, JY; O'Brien, T; Nicol, D; Challacombe, B; Beers, SA; Turajlic, S; Gore, M; Larkin, J; Swanton, C; Chester, KA; Pule, M; Ravetch, JV; Marafioti, T; Peggs, KS; Quezada, SA; - view fewer (2017) Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity , 46 (4) pp. 577-586. 10.1016/j.immuni.2017.03.013.

Varrault, A; Dantec, C; Le Digarcher, A; Chotard, L; Bilanges, B; Parrinello, H; Dubois, E; ... Journot, L; + view all Varrault, A; Dantec, C; Le Digarcher, A; Chotard, L; Bilanges, B; Parrinello, H; Dubois, E; Rialle, S; Severac, D; Bouschet, T; Journot, L; - view fewer (2017) Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network. Nucleic Acids Research , 45 (18) pp. 10466-10480. 10.1093/nar/gkx672.

Virdee, PS; Moschandreas, J; Gebski, V; Love, SB; Francis, EA; Wasan, HS; van Hazel, G; ... Sharma, RA; + view all Virdee, PS; Moschandreas, J; Gebski, V; Love, SB; Francis, EA; Wasan, HS; van Hazel, G; Gibbs, P; Sharma, RA; - view fewer (2017) Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer. JMIR Res Protoc , 6 (3) , Article e43. 10.2196/resprot.7201.

Vivekanandan, S; Landau, DB; Counsell, N; Warren, DR; Khwanda, A; Rosen, SD; Parsons, E; ... Fenwick, JD; + view all Vivekanandan, S; Landau, DB; Counsell, N; Warren, DR; Khwanda, A; Rosen, SD; Parsons, E; Ngai, Y; Farrelly, L; Hughes, L; Hawkins, MA; Fenwick, JD; - view fewer (2017) The Impact of Cardiac Radiation Dosimetry on Survival After Radiation Therapy for Non-Small Cell Lung Cancer. International Journal of Radiation Oncology Biology Physics , 99 (1) pp. 51-60. 10.1016/j.ijrobp.2017.04.026.

Vlachodimitropoulou, E; Chen, Y-L; Garbowski, M; Koonyosying, P; Psaila, B; Sola-Visner, M; Cooper, N; ... Porter, J; + view all Vlachodimitropoulou, E; Chen, Y-L; Garbowski, M; Koonyosying, P; Psaila, B; Sola-Visner, M; Cooper, N; Hider, R; Porter, J; - view fewer (2017) Eltrombopag: a powerful chelator of cellular or extracellular iron(III) alone or combined with a second chelator. Blood , 130 (17) pp. 1923-1933. 10.1182/blood-2016-10-740241.

Volpi, D; Tullis, IDC; Barber, PR; Augustyniak, EM; Smart, SC; Vallis, KA; Vojnovic, B; (2017) Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery. Biomedical Optics Express , 8 (7) pp. 3232-3247. 10.1364/BOE.8.003232.

von Karstedt, S; Montinaro, A; Walczak, H; (2017) Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy. Nature Reviews Cancer , 17 (6) pp. 352-366. 10.1038/nrc.2017.28.

Vos, JM; Notermans, NC; D'Sa, S; Lunn, MP; van der Pol, WL; Kraan, W; Reilly, MM; ... Minnema, MC; + view all Vos, JM; Notermans, NC; D'Sa, S; Lunn, MP; van der Pol, WL; Kraan, W; Reilly, MM; Chalker, J; Gupta, R; Kersten, M-J; Pals, ST; Minnema, MC; - view fewer (2017) High prevalence of the MYD88 L265P mutation in IgM anti-MAG paraprotein-associated peripheral neuropathy. [Letter]. Journal of Neurology, Neurosurgery & Psychiatry , 89 (9) pp. 1007-1009. 10.1136/jnnp-2017-316689.

Waked, I; Berhane, S; Toyoda, H; Chan, SL; Stern, N; Palmer, D; Tada, T; ... Johnson, PJ; + view all Waked, I; Berhane, S; Toyoda, H; Chan, SL; Stern, N; Palmer, D; Tada, T; Yeo, W; Mo, F; Bettinger, D; Kirstein, MM; Iñarrairaegui, M; Gomaa, A; Vogel, A; Meyer, T; Sangro, B; Lai, P; Kumada, T; Johnson, PJ; - view fewer (2017) Transarterial chemo-embolisation of hepatocellular carcinoma: impact of liver function and vascular invasion. British Journal of Cancer , 116 pp. 448-454. 10.1038/bjc.2016.423.

Wan, MY; Endozo, R; Michopoulou, S; Shortman, R; Rodriguez-Justo, M; Menezes, L; Yusuf, S; ... Groves, A; + view all Wan, MY; Endozo, R; Michopoulou, S; Shortman, R; Rodriguez-Justo, M; Menezes, L; Yusuf, S; Richards, T; Wild, D; Waser, B; Reubi, JC; Groves, A; - view fewer (2017) PETCT Imaging of Unstable Carotid Plaque with Ga-68 labelled Somatostatin Receptor Ligand. The Journal of Nuclear Medicine , 58 (5) pp. 774-780. 10.2967/jnumed.116.181438.

Wasan, HS; Gibbs, P; Sharma, NK; Taieb, J; Heinemann, V; Ricke, J; Peeters, M; ... Sharma, RA; + view all Wasan, HS; Gibbs, P; Sharma, NK; Taieb, J; Heinemann, V; Ricke, J; Peeters, M; Findlay, M; Weaver, A; Mills, J; Wilson, C; Adams, R; Francis, A; Moschandreas, J; Virdee, PS; Dutton, P; Love, S; Gebski, V; Gray, A; FOXFIRE trial investigators, .; SIRFLOX trial investigators, .; FOXFIRE-Global trial investigators, .; van Hazel, G; Sharma, RA; - view fewer (2017) First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials. The Lancet Oncology 10.1016/S1470-2045(17)30457-6. (In press).

Weil, BD; Jenkins, MJ; Uddin, S; Bracewell, DG; Wellings, D; Farid, SS; Veraitch, F; (2017) An integrated experimental and economic evaluation of cell therapy affinity purification technologies. Regenerative Medicine , 12 (4) pp. 397-417. 10.2217/rme-2016-0156.

Weitsman, G; Mitchell, NJ; Evans, R; Cheung, A; Kalber, TL; Bofinger, R; Fruhwirth, GO; ... Ng, T; + view all Weitsman, G; Mitchell, NJ; Evans, R; Cheung, A; Kalber, TL; Bofinger, R; Fruhwirth, GO; Keppler, M; Wright, ZV; Barber, PR; Gordon, P; de Koning, T; Wulaningsih, W; Sander, K; Vojnovic, B; Ameer-Beg, S; Lythgoe, M; Arnold, JN; Årstad, E; Festy, F; Hailes, HC; Tabor, AB; Ng, T; - view fewer (2017) Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor. Oncogene , 36 pp. 3618-3628. 10.1038/onc.2016.522.

Wheeler, GM; Sweeting, MJ; Mander, AP; (2017) Toxicity-dependent feasibility bounds for the Escalation with Overdose Control approach in phase I cancer trials. Statistics in Medicine , 36 (16) pp. 2499-2513. 10.1002/sim.7280.

Wheeler, GM; Sweeting, MJ; Mander, AP; Lee, SM; Cheung, YKK; (2017) Modelling semi-attributable toxicity in dual-agent phase I trials with non-concurrent drug administration. Statistics in Medicine , 36 (2) pp. 225-241. 10.1002/sim.6912.

Wong, YNS; Joshi, K; Pule, M; Peggs, KS; Swanton, C; Quezada, SA; Linch, M; (2017) Evolving adoptive cellular therapies in urological malignancies. Lancet Oncology , 18 (6) E341-E353. 10.1016/S1470-2045(17)30327-3.

Wood, G; Grenader, T; Nash, S; Adams, R; Kaplan, R; Fisher, D; Maughan, T; Wood, G; Grenader, T; Nash, S; Adams, R; Kaplan, R; Fisher, D; Maughan, T; Bridgewater, J; - view fewer (2017) Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study. Anti-Cancer Drugs , 28 (5) pp. 546-550. 10.1097/CAD.0000000000000488.

Wulaningsih, W; Holmberg, L; Abeler-Dörner, L; Ng, T; Rohrmann, S; Van Hemelrijck, M; (2017) Correction: Associations of C-Reactive Protein, Granulocytes and Granulocyte-to-Lymphocyte Ratio with Mortality from Breast Cancer in Non-Institutionalized American Women. PLoS One , 11 (8) , Article e0161418. 10.1371/journal.pone.0161418.

Yang, J; Milasta, S; Hu, D; AlTahan, AM; Interiano, RB; Zhou, J; Davidson, J; ... Davidoff, AM; + view all Yang, J; Milasta, S; Hu, D; AlTahan, AM; Interiano, RB; Zhou, J; Davidson, J; Low, J; Lin, W; Bao, J; Goh, P; Nathwani, AC; Wang, R; Wang, Y; Ong, SS; Boyd, VA; Young, B; Das, S; Shelat, A; Wu, Y; Li, Z; Zheng, JJ; Mishra, A; Cheng, Y; Qu, C; Peng, J; Green, DR; White, S; Guy, RK; Chen, T; Davidoff, AM; - view fewer (2017) Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox. Cancer Research , 77 (17) pp. 4626-4638. 10.1158/0008-5472.CAN-16-0826.

Yang, Z; Hackshaw, A; Feng, Q; Fu, X; Zhang, Y; Mao, C; Tang, J; (2017) Comparison of gefitinib, erlotinib and afatinib in non-small cell lung cancer: A meta-analysis. International Journal of Cancer , 140 (12) pp. 2805-2819. 10.1002/ijc.30691.

Yogev, O; Henderson, S; Hayes, MJ; Marelli, SS; Ofir-Birin, Y; Regev-Rudzki, N; Herrero, J; Yogev, O; Henderson, S; Hayes, MJ; Marelli, SS; Ofir-Birin, Y; Regev-Rudzki, N; Herrero, J; Enver, T; - view fewer (2017) Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs. PLoS Pathogens , 13 (8) , Article e1006524. 10.1371/journal.ppat.1006524.

Yuan, G-C; Cai, L; Elowitz, M; Enver, T; Fan, G; Guo, G; Irizarry, R; ... Tirosh, I; + view all Yuan, G-C; Cai, L; Elowitz, M; Enver, T; Fan, G; Guo, G; Irizarry, R; Kharchenko, P; Kim, J; Orkin, S; Quackenbush, J; Saadatpour, A; Schroeder, T; Shivdasani, R; Tirosh, I; - view fewer (2017) Challenges and emerging directions in single-cell analysis. Genome Biology , 18 , Article 84. 10.1186/s13059-017-1218-y.

Zheng, SC; Beck, S; Jaffe, AE; Koestler, DC; Hansen, KD; Houseman, AE; Irizarry, RA; Zheng, SC; Beck, S; Jaffe, AE; Koestler, DC; Hansen, KD; Houseman, AE; Irizarry, RA; Teschendorff, AE; - view fewer (2017) Correcting for cell-type heterogeneity in epigenome-wide association studies: revisiting previous analyses. Nature Methods , 14 (3) pp. 216-217. 10.1038/nmeth.4187.

Zinngrebe, J; Walczak, H; (2017) TLRs Go Linear – On the Ubiquitin Edge. Trends in Molecular Medicine , 23 (4) pp. 296-309. 10.1016/j.molmed.2017.02.003.

Book chapter

Ng, K; Ng, SM; Parker, A; (2017) Advances in the Surveillance and Management of Tuberous Sclerosis. In: Maconochie, I, (ed.) Recent Advances in Paediatrics. Jaypee UK: London, UK.

Proceedings paper

Efthymiou, M; Mackie, IJ; Lane, P; Erkan, D; Cohen, H; (2017) High prevalence of activated protein C resistance associated with high avidity anti-protein C antibodies in various antiphospholipid syndrome clinical phenotypes. In: (Proceedings) ISTH 2017.

Noor, K; Hunter, A; Mayer, A; (2017) Analysis of medical arguments from patient experiences expressed on the social web. In: IEA/AIE 2017: Advances in Artificial Intelligence: From Theory to Practice. (pp. pp. 285-294). Springer, Cham

Oaknin, A; Oza, A; Tinker, A; Ray-Coquard, I; Coleman, R; O'Malley, D; Shapira-Frommer, R; ... Kristeleit, RS; + view all Oaknin, A; Oza, A; Tinker, A; Ray-Coquard, I; Coleman, R; O'Malley, D; Shapira-Frommer, R; Leary, A; Chen, L; Provencher, D; Ma, L; Brenton, J; Balmana, J; Giordano, H; Maloney, L; Goble, S; Rolfe, L; McNeish, I; Swisher, E; Kristeleit, RS; - view fewer (2017) Integrated efficacy and safety analysis of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC). In: ECCO: 2017 European Cancer Congress. Abstract Book. (pp. S95-S95). Elsevier

Ralli, GP; McGowan, DR; Chappell, MA; Sharma, RA; Higgins, GS; Fenwick, JD; (2017) 4D-PET reconstruction of dynamic non-small cell lung cancer [18-F]-FMISO-PET data using adaptive-knot cubic B-splines. In: 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). (pp. pp. 1189-1192). IEEE

Conference item

Alrifai, D; (2017) Evaluation of CA 19-9, a predictive biomarker of response and survival in patients undergoing chemotherapy for metastatic pancreatic ductal adenocarcinoma. Presented at: ESMO World Congress on Gastrointestinal Cancer 2018, Barcelona, Spain.

Bailey, C; Bourne, RM; Siow, B; Johnston, EW; Pye, H; Heavey, S; Mertzanidou, T; ... Panagiotaki, E; + view all Bailey, C; Bourne, RM; Siow, B; Johnston, EW; Pye, H; Heavey, S; Mertzanidou, T; Whitaker, H; Freeman, A; Patel, D; Shaw, G; Sridhar, A; Punwani, S; Hawkes, DJ; Alexander, DC; Panagiotaki, E; - view fewer (2017) Validation of VERDICT MRI using fresh and fixed prostate specimens with aligned histological slices. Presented at: 25th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISRM 2017), Honolulu, HI, USA.

Baurain, J; Awada, A; Brunsvig, P; Kristeleit, RS; Loirat, D; Jossang, D; Zitvogel, L; ... Spicer, J; + view all Baurain, J; Awada, A; Brunsvig, P; Kristeleit, RS; Loirat, D; Jossang, D; Zitvogel, L; Kroemer, G; Marabelle, A; Rekdal, O; Sveinbjornsson, B; Wold, H; Nicolaisen, B; Saunders, A; Spicer, J; - view fewer (2017) A phase I dose escalation study of intra-tumoral LTX-315 as monotherapy or in combination with either ipilimumab or pembrolizumab in patients with transdermally accessible tumors (NCT01986426). Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.

Dillon, MT; Espinasse, A; Ellis, S; Mohammed, K; Grove, LG; McLellan, L; Smith, SA; ... Harrington, KJ; + view all Dillon, MT; Espinasse, A; Ellis, S; Mohammed, K; Grove, LG; McLellan, L; Smith, SA; Ross, G; Adeleke, S; Woo, K; Josephides, E; Spicer, JF; Forster, MD; Harrington, KJ; - view fewer (2017) A Phase I dose-escalation study of ATR inhibitor monotherapy with AZD6738 in advanced solid tumors (PATRIOT Part A). Presented at: Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC.

Kristeleit, RS; Lorusso, D; Oaknin, A; Safra, T; Swisher, EM; Bondarenko, IM; Huzarski, T; ... Oza, A; + view all Kristeleit, RS; Lorusso, D; Oaknin, A; Safra, T; Swisher, EM; Bondarenko, IM; Huzarski, T; Klat, J; Moiseyenko, V; Poka, RL; Viola, LS; Tankersley, C; Maloney, L; Goble, S; Unger, C; Dowson, A; Giordano, H; Oza, A; - view fewer (2017) 988TiP: ARIEL4: An international, randomised phase 3 study of the PARP inhibitor rucaparib vs chemotherapy for the treatment of BRCA-mutated, relapsed, high-grade ovarian cancer. Presented at: 42nd ESMO Congress (ESMO 2017), Madrid, Spain.

Kristeleit, RS; Miller, R; Sellers, L; Brown, N; Devlin, M; Woo, K; Boyd, A; ... Linch, M; + view all Kristeleit, RS; Miller, R; Sellers, L; Brown, N; Devlin, M; Woo, K; Boyd, A; Morris, G; D'Aquino, V; Hughes, S; Forster, M; Linch, M; - view fewer (2017) A first-in-human Phase I/II, dose escalation, pharmacokinetic study to assess safety and tolerability of VAL201 in advanced prostate cancer. Presented at: 15th International Congress on Targeted Anticancer Therapies (TAT 2017), Paris, France.

Miller, RE; Devlin, M; Brown, N; Woo, K; Grunewald, T; Speirs, A; Mitchison, M; ... Kristeleit, R; + view all Miller, RE; Devlin, M; Brown, N; Woo, K; Grunewald, T; Speirs, A; Mitchison, M; Lockley, M; McCormack, M; Ledermann, J; Forster, M; Meyer, T; Kristeleit, R; - view fewer (2017) Guidance by molecular selection improves the outcome of early phase treatment for gynecological (GYN) cancers. Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.

Robillard, L; Nguyen, M; Loehr, A; Orsulic, S; Kristeleit, RS; Lin, K; Raponi, M; ... Simmons, AD; + view all Robillard, L; Nguyen, M; Loehr, A; Orsulic, S; Kristeleit, RS; Lin, K; Raponi, M; Harding, TC; Simmons, AD; - view fewer (2017) Preclinical evaluation of the PARP inhibitor rucaparib in combination with PD-1 and PD-L1 inhibition in a syngeneic BRCA1 mutant ovarian cancer model. Presented at: AACR Annual Meeting 2017, Washington, D.C., USA.

Spicer, JF; Baurain, JF; Awada, A; Kristeleit, RS; Jossang, DE; Marabelle, A; Loirat, D; ... Brunsvig, P; + view all Spicer, JF; Baurain, JF; Awada, A; Kristeleit, RS; Jossang, DE; Marabelle, A; Loirat, D; Wold, H; Nicolaisen, B; Rekdal, O; Olsen, WM; Saunders, A; Brunsvig, P; - view fewer (2017) LTX-315, an oncolytic peptide, to convert immunogenically 'cold' tumors to 'hot' in patients with advanced or metastatic tumours: Results from an ongoing phase I study. Presented at: American Society of Clinical Oncology Annual Meeting 2017, Chicago, IL, USA. (In press).

Poster

Marabelle, A; Baurain, J-F; Awada, A; Kristeleit, RS; Jossang, D-E; Jebsen, N-L; Loirat, D; ... Spicer, J; + view all Marabelle, A; Baurain, J-F; Awada, A; Kristeleit, RS; Jossang, D-E; Jebsen, N-L; Loirat, D; Saunders, A; Olsen, W; Nicolaisen, B; Sveinbjornsson, B; Gjerstad, VS; Rekdal, O; Brunsvig, P; Galon, J; Hermitte, F; Gjertsen, B-T; Armstrong, A; Spicer, J; - view fewer (2017) LTX‐315, an oncolytic peptide converts "cold" tumors to "hot" in a majority of patients with advanced cancer: results from an ongoing phase I study. Presented at: 32nd Annual Meeting and Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2017): Part Two, National Harbor, Maryland, USA.

Miller, R; Devlin, M-J; Brown, NF; Grunewald, T; McCormack, M; Lockley, M; Ledermann, JA; ... Kristeleit, RS; + view all Miller, R; Devlin, M-J; Brown, NF; Grunewald, T; McCormack, M; Lockley, M; Ledermann, JA; Meyer, T; Forster, MD; Kristeleit, RS; - view fewer (2017) Outcome of patients with advanced endometrial and cervical cancer treated in a phase 1 unit. Presented at: 2017 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL, USA.

Thesis

A, Deli; (2017) The role of promyelocytic leukemia (PML) protein in regulation of adult subventricular zone neurogenesis. Doctoral thesis , UCL (University College London).

Agliardi, Giulia; (2017) Development of a Chimeric Antigen Receptor (CAR) - based T cell therapy for glioblastoma. Doctoral thesis (Ph.D), UCL (University College London).

Breeze, Charles E; (2017) Epigenetics of complex traits and diseases. Doctoral thesis (Ph.D), UCL (University College London).

Colling, Richard T; (2017) The diagnostic molecular pathology of colorectal carcinoma using automated PCR. Doctoral thesis (M.D), UCL (University College London).

De Ascensão Santos e Sousa, Pedro Miguel; (2017) A systems immunology approach to graft-versus-host disease. Doctoral thesis , UCL (University College London).

Domogala, AJ; (2017) The characterisation of NK cells generated in vitro from cord blood haematopoietic stem cells. Doctoral thesis , UCL (University College London).

Garbowski, MW; (2017) Molecular and clinical factors affecting myocardial iron retention in transfusional haemosiderosis. Doctoral thesis , UCL (University College London).

Hill, Mark Stephen; (2017) The genetic basis of sexual antagonism in Drosophila melanogaster. Doctoral thesis , UCL (University College London).

Holme, Harriet Katie; (2017) Identifying Genetic Dependencies and Potential Novel Therapeutic Targets for Osteosarcoma. Doctoral thesis (Ph.D), UCL (University College London).

Hotblack, AC; (2017) Characterising the role of dendritic cells in TCR gene therapy. Doctoral thesis , UCL (University College London).

Kataria, M; (2017) How does Cdc14 order exit from mitosis? Doctoral thesis , UCL (University College London).

Khan, AA; (2017) Study of serial markers of biological response in rectal cancer patients receiving preoperative chemoradiotherapy with or without biological agents. Doctoral thesis , UCL (University College London).

Kinna, AW; (2017) Improved production and purification of recombinant proteins from mammalian expression systems. Doctoral thesis , UCL (University College London).

Kramer, AM; (2017) Delineating the impact of binding-domain affinity and kinetic properties on Chimeric Antigen Receptor T-cell function. Doctoral thesis , UCL (University College London).

Kularatne, BY; (2017) The identification of novel biomarkers to guide treatment in endometrial cancer. Doctoral thesis , UCL (University College London).

Kupka, S; (2017) Regulation of theTNFR1-signalling complex by LUBAC and associated deubiquitinases. Doctoral thesis , UCL (University College London).

Lee, Doyoung; (2017) Investigation of mechanisms for enhancing expression of human FVIII in vitro; application to therapeutic protein production. Doctoral thesis , UCL (University College London).

Lee, LSH; (2017) APRIL based therapeutic strategies to target BCMA and TACI in multiple myeloma. Doctoral thesis , UCL (University College London).

Lowry, LM; (2017) Impact of constitutional polymorphisms in immune effector mechanisms on clinical response to rituximab therapy in patients with follicular lymphoma. Doctoral thesis , UCL (University College London).

Maciocia, PM; (2017) Targeting the T-cell Receptor Beta Constant Region for Investigation and Immunotherapy of T-cell Malignancies. Doctoral thesis , UCL (University College London).

Marelli, S; (2017) Characterization of molecular pathways regulating the latent-to-lytic switch in γ-herpesviruses. Doctoral thesis , UCL (University College London).

Paredes Moscosso, Solange Rosa; (2017) ROR1 as a target for cancer immunotherapy. Doctoral thesis (Ph.D), UCL (University College London).

Perera, Nirmal; (2017) The role of YAP 1 in regulating epithelial-mesenchymal transition. Doctoral thesis (Ph.D), UCL (University College London).

Powell, BE; (2017) Identification of Conditions to Induce and Maintain Naive Human Pluripotency. Doctoral thesis , UCL (University College London).

Ravinarayana Chakravarthy, A; (2017) The Molecular Landscape of HPV-driven Tumourigenesis. Doctoral thesis , UCL (University College London).

Reed, M; (2017) Characterisation of pathogenic pathways within the bone microenvironment of Gaucher Disease which contribute to bone pathology and haematological malignancy. Doctoral thesis , UCL (University College London).

Reichert, Matthias; (2017) Regulation of TNFR1 signalling by LUBAC-dependent and -associated proteins. Doctoral thesis , UCL (University College London).

Shimizu, Y; (2017) Molecular and functional characterisation of linear ubiquitination in the liver. Doctoral thesis , UCL (University College London).

Taraborrelli, L; (2017) The Role Of Lubac In Tissue Homeostasis And Cancer. Doctoral thesis (Ph.D), UCL (University College London).

Valentine, HE; (2017) Characterisation of a novel STAT3 inhibitor, VS-43, and the role of STAT3 in the repair of DNA-interstrand crosslinks. Doctoral thesis , UCL (University College London).

Vlachodimitropoulou Koumoutsea, E; (2017) Novel approaches to iron chelation therapy: novel combinations and novel compounds. Doctoral thesis , UCL (University College London).

Weil, BD; (2017) Purification Of Progenitor Photoreceptors Derived From The Directed Differentiation Of Human Pluripotent Stem Cells. Doctoral thesis , UCL (University College London).

This list was generated on Mon Nov 18 00:11:48 2024 GMT.