Nunes, JPM;
Vassileva, V;
Robinson, E;
Morais, M;
Smith, MEB;
Pedley, RB;
Caddick, S;
... Chudasama, V; + view all
(2017)
Use of a next generation maleimide in combination with THIOMAB (TM) antibody technology delivers a highly stable, potent and near homogeneous THIOMAB (TM) antibody-drug conjugate (TDC).
RSC ADVANCES
, 7
(40)
pp. 24828-24832.
10.1039/c7ra04606e.
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| Type: | Article |
|---|---|
| Title: | Use of a next generation maleimide in combination with THIOMAB (TM) antibody technology delivers a highly stable, potent and near homogeneous THIOMAB (TM) antibody-drug conjugate (TDC) |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/c7ra04606e |
| Publisher version: | http://dx.doi.org/10.1039/c7ra04606e |
| Additional information: | This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. |
| Keywords: | Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, SITE-SPECIFIC CONJUGATION, THERAPEUTIC INDEX, AMINO-ACIDS, STABILITY, EFFICACY, ADCS, PHARMACOKINETICS, ENABLES, PROTEIN, BIOCONJUGATION |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1557778 |
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