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Guidelines for screening and management of late and long-term consequences of myeloma and its treatment

Snowden, JA; Greenfield, DM; Bird, JM; Boland, E; Bowcock, S; Fisher, A; Low, E; ... UK Myeloma Forum (UKMF) and the British Society for Haematology, .; + view all (2017) Guidelines for screening and management of late and long-term consequences of myeloma and its treatment. British Journal of Haematology , 176 (6) pp. 888-907. 10.1111/bjh.14514. Green open access

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Abstract

A growing population of long-term survivors of myeloma is now accumulating the 'late effects' not only of myeloma itself, but also of several lines of treatment given throughout the course of the disease. It is thus important to recognise the cumulative burden of the disease and treatment-related toxicity in both the stable and active phases of myeloma, some of which is unlikely to be detected by routine monitoring. We summarise here the evidence for the key late effects in long-term survivors of myeloma, including physical and psychosocial consequences (in Parts 1 and 2 respectively), and recommend the use of late-effects screening protocols in detection and intervention. The early recognition of late effects and effective management strategies should lead to an improvement in the management of myeloma patients, although evidence in this area is currently limited and further research is warranted.

Type: Article
Title: Guidelines for screening and management of late and long-term consequences of myeloma and its treatment
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/bjh.14514
Publisher version: http://dx.doi.org/10.1111/bjh.14514
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: chemotherapy, haematopoietic stem cell transplantation, late effects, myeloma, quality of life
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery.ucl.ac.uk/id/eprint/1538421
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