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Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion

Davis, BA; Allard, S; Qureshi, A; Porter, JB; Pancham, S; Win, N; Cho, G; ... British Society for Haematology, .; + view all (2017) Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion. British Journal of Haematology , 176 (2) pp. 192-209. 10.1111/bjh.14383. Green open access

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Abstract

Red cell transfusion has an important role in the management of sickle cell disease (SCD) in both emergency and elective settings. However, because of insufficient randomised data, it is not always clear when or how to use red cell transfusion. A companion guideline, Guidelines on red cell transfusion in sickle cell disease Part I: principles and laboratory aspects, addresses the general principles of transfusion practice in SCD (Davis et al, 2016, BJH in press). The present guideline examines current available evidence on indications for transfusion in SCD. This may not be appropriate for all clinical scenarios and clinical decisions must be based on individual patient considerations. In both guidelines, the term sickle cell disease refers to all genotypes of the disease, and sickle cell anaemia to the homozygous state (SS).

Type: Article
Title: Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/bjh.14383
Publisher version: https://doi.org/10.1111/bjh.14383
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: indications, red cell transfusion, sickle cell disease, Adolescent, Anemia, Sickle Cell, Child, Child, Preschool, Erythrocyte Transfusion, Guidelines as Topic, Humans
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
URI: https://discovery.ucl.ac.uk/id/eprint/10072500
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