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Use of the complement inhibitor Coversin to treat HSCT-associated TMA

Goodship, THJ; Pinto, F; Weston-Davies, WH; Silva, J; Nishimura, J-I; Nunn, MA; Mackie, I; ... Veys, P; + view all (2017) Use of the complement inhibitor Coversin to treat HSCT-associated TMA. Blood Advances , 1 (16) pp. 1254-1258. 10.1182/bloodadvances.2016002832. Green open access

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Abstract

Finding an inherited complement abnormality in HSCT-associated TMA provides a rationale for the use of a complement inhibitor.Alternative complement inhibitors such as Coversin should be considered in patients who are resistant to eculizumab.

Type: Article
Title: Use of the complement inhibitor Coversin to treat HSCT-associated TMA
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1182/bloodadvances.2016002832
Publisher version: http://doi.org/10.1182/bloodadvances.2016002832
Language: English
Additional information: © 2017 by The American Society of Hematology. This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10041314
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