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Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group

Stacchiotti, S; Gronchi, A; Fossati, P; Akiyama, T; Alapetite, C; Baumann, M; Blay, JY; ... Sommer, J; + view all (2017) Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group. Annals of Oncology , 28 (6) pp. 1230-1242. 10.1093/annonc/mdx054. Green open access

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Abstract

Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until recently, there was no consensus among experts regarding appropriate clinical management of chordoma, resulting in inconsistent care and suboptimal outcomes for many patients. To address this shortcoming, the European Society of Medical Oncology (ESMO) and the Chordoma Foundation, the global chordoma patient advocacy group, convened a multi-disciplinary group of chordoma specialists to define by consensus evidence-based best practices for the optimal approach to chordoma. In January 2015, the first recommendations of this group were published, covering the management of primary and metastatic chordomas. Additional evidence and further discussion were needed to develop recommendations about the management of local-regional failures. Thus, ESMO and CF convened a second consensus group meeting in November 2015 to address the treatment of locally relapsed chordoma. This meeting involved over 60 specialists from Europe, the United States and Japan with expertise in treatment of patients with chordoma. The consensus achieved during that meeting is the subject of the present publication and complements the recommendations of the first position paper.

Type: Article
Title: Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/annonc/mdx054
Publisher version: http://dx.doi.org/10.1093/annonc/mdx054
Language: English
Additional information: VC The Author 2017. Published by Oxford University Press on behalf of the European Society for Medical Oncology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Keywords: Oncology, chordoma, sarcoma, relapse, radiotherapy, surgery, chemotherapy, SKULL BASE CHORDOMAS, DOSE PHOTON/PROTON RADIOTHERAPY, ENDOSCOPIC ENDONASAL APPROACH, PHASE-II TRIAL, RADIATION-THERAPY, SACRAL CHORDOMA, PROTON THERAPY, CERVICAL-SPINE, STEREOTACTIC RADIOSURGERY, NASOPHARYNGEAL CARCINOMA
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Pathology
URI: https://discovery.ucl.ac.uk/id/eprint/1561356
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