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Article

Ávila-Sansores, S-M; Rodríguez-Gómez, G; Tachtsidis, I; Orihuela-Espina, F; (2020) Interpolated functional manifold for functional near-infrared spectroscopy analysis at group level. Neurophotonics , 7 (4) , Article 045009. 10.1117/1.NPh.7.4.045009. Green open access
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Ayaz, Hasan; Baker, Wesley B; Blaney, Giles; Boas, David A; Bortfeld, Heather; Brady, Kenneth; Brake, Joshua; ... Zhou, Wenjun; + view all (2022) Optical imaging and spectroscopy for the study of the human brain: status report. Neurophotonics , 9 (Suppl 2) 10.1117/1.NPh.9.S2.S24001. Green open access
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Bainbridge, A; Tachtsidis, I; Faulkner, SD; Price, D; Zhu, T; Baer, E; Broad, KD; ... Golay, X; + view all (2014) Brain mitochondrial oxidative metabolism during and after cerebral hypoxia-ischemia studied by simultaneous phosphorus magnetic-resonance and broadband near-infrared spectroscopy. Neuroimage , 102 (1) 173 - 183. 10.1016/j.neuroimage.2013.08.016. Green open access
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Bale, G; Elwell, CE; Tachtsidis, I; (2016) From Jöbsis to the present day: a review of clinical near-infrared spectroscopy measurements of cerebral cytochrome-c-oxidase. Journal of Biomedical Optics , 21 (9) , Article 91307. 10.1117/1.JBO.21.9.091307. Green open access
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Bale, G; Mitra, S; de Roever, I; Sokolska, M; Price, D; Bainbridge, A; Gunny, R; ... Tachtsidis, I; + view all (2019) Oxygen dependency of mitochondrial metabolism indicates outcome of newborn brain injury. Journal of Cerebral Blood Flow & Metabolism , 39 (10) pp. 2035-2047. 10.1177/0271678X18777928. Green open access
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Bale, G; Mitra, S; Tachtsidis, I; (2020) Metabolic brain measurements in the newborn: Advances in optical technologies. Physiological Reports , 8 (17) , Article e14548. 10.14814/phy2.14548. Green open access
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Bale, G; Oliver-Taylor, A; Fierens, I; Broad, K; Hassell, J; Kawano, G; Rostami, J; ... Tachtsidis, I; + view all (2014) Investigation of cerebral autoregulation in the newborn piglet during anaesthesia and surgery. Advances in Experimental Medicine and Biology , 812 165 - 171. 10.1007/978-1-4939-0620-8_22. Green open access
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Bale, G; Rajaram, A; Kewin, M; Morrison, L; Bainbridge, A; Diop, M; St Lawrence, K; (2018) Broadband NIRS Cerebral Cytochrome-C-Oxidase Response to Anoxia Before and After Hypoxic-Ischaemic Injury in Piglets. Advances in Experimental Medicine and Biology , 1072 pp. 151-156. 10.1007/978-3-319-91287-5_24. Green open access
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Bale, G; Rajaram, A; Kewin, M; Morrison, L; Bainbridge, A; Liu, L; Anazodo, U; ... Tachtsidis, I; + view all (2021) Multimodal Measurements of Brain Tissue Metabolism and Perfusion in a Neonatal Model of Hypoxic-Ischaemic Injury. Advances in Experimental Medicine and Biology , 1269 pp. 203-208. 10.1007/978-3-030-48238-1_32. Green open access
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Bale, G; Taylor, N; Mitra, S; Sudakou, A; de Roever, I; Meek, J; Robertson, N; (2020) Near-Infrared Spectroscopy Measured Cerebral Blood Flow from Spontaneous Oxygenation Changes in Neonatal Brain Injury. Oxygen Transport to Tissue XLI , 1232 pp. 3-9. 10.1007/978-3-030-34461-0_1. Green open access
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Boot, E; Levy, A; Gaeta, G; Gunasekara, N; Parkkinen, E; Kontaris, E; Jacquot, M; (2024) fNIRS a novel neuroimaging tool to investigate olfaction, olfactory imagery, and crossmodal interactions: a systematic review. Frontiers in Neuroscience , 18 , Article 1266664. 10.3389/fnins.2024.1266664. Green open access
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Brigadoi, S; Phan, P; Highton, D; Powell, S; Cooper, RJ; Hebden, J; Smith, M; ... Gibson, AP; + view all (2017) Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data. Neurophotonics , 4 (2) , Article 021105. 10.1117/1.NPh.4.2.021105. Green open access
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Broad, KD; Fierens, I; Fleiss, B; Rocha-Ferreira, E; Ezzati, M; Hassell, J; Alonso-Alconada, D; ... Robertson, NJ; + view all (2016) Inhaled 45-50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia. Neurobiology of Disease , 87 pp. 29-38. 10.1016/j.nbd.2015.12.001. Green open access
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Bruckmaier, M; Tachtsidis, I; Phan, P; Lavie, N; (2020) Attention and capacity limits in perception: A cellular metabolism account. Journal of Neuroscience , Article JN-RM-2368-19. 10.1523/JNEUROSCI.2368-19.2020. (In press). Green open access
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Burgess, Paul W; Crum, James; Pinti, Paola; Aichelburg, Clarisse; Oliver, Dominic; Lind, Frida; Power, Sarah; ... Hamilton, Antonia; + view all (2022) Prefrontal cortical activation associated with prospective memory while walking around a real-world street environment. NeuroImage , 258 , Article 119392. 10.1016/j.neuroimage.2022.119392. Green open access
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Caicedo, A; Papademetriou, MD; Elwell, CE; Hoskote, A; Elliott, MJ; Van Huffel, S; Tachtsidis, I; (2013) Canonical correlation analysis in the study of cerebral and peripheral haemodynamics interrelations with systemic variables in neonates supported on ECMO. Adv Exp Med Biol , 765 23 - 29. 10.1007/978-1-4614-4989-8_4. Green open access
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Caicedo, A; Varon, C; Hunyadi, B; Papademetriou, M; Tachtsidis, I; Van Huffel, S; (2016) Decomposition of Near-Infrared Spectroscopy Signals Using Oblique Subspace Projections: Applications in Brain Hemodynamic Monitoring. Frontiers in Physiology , 7 , Article 515. 10.3389/fphys.2016.00515. Green open access
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Caldwell, M; Hapuarachchi, T; Highton, D; Elwell, C; Smith, M; Tachtsidis, I; (2015) BrainSignals Revisited: Simplifying a Computational Model of Cerebral Physiology. PLoS One , 10 (5) , Article e0126695. 10.1371/journal.pone.0126695. Green open access
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Caldwell, M; Moroz, T; Hapuarachchi, T; Bainbridge, A; Robertson, NJ; Cooper, CE; Tachtsidis, I; (2015) Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia. PLoS One , 10 (10) , Article e0140171. 10.1371/journal.pone.0140171. Green open access
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Caldwell, M; Scholkmann, F; Wolf, U; Wolf, M; Elwell, C; Tachtsidis, I; (2016) Modelling confounding effects from extracerebral contamination and systemic factors on functional near-infrared spectroscopy. NeuroImage , 143 pp. 91-105. 10.1016/j.neuroimage.2016.08.058. Green open access
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Cañigueral, R; Zhang, X; Noah, JA; Tachtsidis, I; Hamilton, AFDC; Hirsch, J; (2021) Facial and neural mechanisms during interactive disclosure of biographical information. NeuroImage , 226 , Article 117572. 10.1016/j.neuroimage.2020.117572. Green open access
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Caredda, Charly; Lange, Frédéric; Giannoni, Luca; Ezhov, Ivan; Picart, Thiébaud; Guyotat, Jacques; Tachtsidis, Ilias; (2025) Digital instrument simulator to optimize the development of hyperspectral systems: application for intraoperative functional brain mapping. Journal of Biomedical Optics , 30 (2) , Article 023513. 10.1117/1.JBO.30.2.023513. Green open access
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Chisholm, KI; Ida, KK; Davies, AL; Papkovsky, DB; Singer, M; Dyson, A; Tachtsidis, I; ... Smith, KJ; + view all (2016) In Vivo Imaging of Flavoprotein Fluorescence During Hypoxia Reveals the Importance of Direct Arterial Oxygen Supply to Cerebral Cortex Tissue. Advances in Experimental Medicine and Biology , 876 pp. 233-239. 10.1007/978-1-4939-3023-4_29. Green open access
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Chisholm, KI; Ida, KK; Davies, AL; Tachtsidis, I; Papkovsky, DB; Dyson, A; Singer, M; ... Smith, KJ; + view all (2016) Hypothermia protects brain mitochondrial function from hypoxemia in a murine model of sepsis. Journal of Cerebral Blood Flow and Metabolism , 36 (11) 1955 -1964. 10.1177/0271678X15606457. Green open access
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Chitnis, D; Airantzis, D; Highton, D; Williams, R; Phan, P; Giagka, V; Powell, S; ... Everdell, N; + view all (2016) Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo. Review of Scientific Instruments , 87 (6) , Article 065112. 10.1063/1.4954722. Green open access
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De Felice, S; Hakim, U; Gunasekara, N; Pinti, P; Tachtsidis, I; Hamilton, A; (2024) Having a chat and then watching a movie: how social interaction synchronises our brains during co-watching. Oxford Open Neuroscience , 3 , Article kvae006. 10.1093/oons/kvae006. Green open access
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de Roever, I; Bale, G; Cooper, RJ; Tachtsidis, I; (2017) Functional NIRS Measurement of Cytochrome-C-Oxidase Demonstrates a More Brain-Specific Marker of Frontal Lobe Activation Compared to the Haemoglobins. Advances in Experimental Medicine and Biology , 977 pp. 141-147. 10.1007/978-3-319-55231-6_19. Green open access
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de Roever, I; Bale, G; Mitra, S; Meek, J; Robertson, NJ; Tachtsidis, I; (2018) Investigation of the Pattern of the Hemodynamic Response as Measured by Functional Near-Infrared Spectroscopy (fNIRS) Studies in Newborns, Less Than a Month Old: A Systematic Review. Frontiers in Human Neuroscience , 12 , Article 371. 10.3389/fnhum.2018.00371. Green open access
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Desai, RA; Davies, AL; Del Rossi, N; Tachrount, M; Dyson, A; Gustavson, B; Kaynezhad, P; ... Smith, KJ; + view all (2020) Nimodipine reduces dysfunction and demyelination in models of multiple sclerosis. Annals of Neurology , 88 (1) pp. 123-136. 10.1002/ana.25749. Green open access
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Dunne, L; Hebden, J; Tachtsidis, I; (2014) Development of a near infrared multi-wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism. Adv Exp Med Biol , 812 181 - 186. 10.1007/978-1-4939-0620-8_24. Green open access
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Ezzati, M; Bainbridge, A; Broad, KD; Kawano, G; Oliver-Taylor, A; Rocha-Ferreira, E; Alonso-Alconada, D; ... Robertson, NJ; + view all (2015) Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter. Journal of Cerebral Blood Flow & Metabolism , 36 (8) pp. 1396-1411. 10.1177/0271678X15608862. Green open access
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Ezzati, M; Kawano, G; Rocha-Ferreira, E; Alonso-Alconada, D; Hassell, JK; Broad, KD; Fierens, I; ... Robertson, NJ; + view all (2017) Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia. Developmental Neuroscience 10.1159/000458438. (In press). Green open access
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Gaeta, Giuliano; Gunasekara, Natalie; Pinti, Paola; Levy, Andrew; Parkkinen, Emilia; Kontaris, Emily; Tachtsidis, Ilias; (2024) Naturalistic approach to investigate the neural correlates of a laundry cycle with and without fragrance. Biomedical Optics Express , 15 (9) pp. 5461-5478. 10.1364/BOE.528275. Green open access
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Ghosh, A; Highton, D; Kolyva, C; Tachtsidis, I; Elwell, CE; Smith, M; (2017) Hyperoxia results in increased aerobic metabolism following acute brain injury. Journal of Cerebral Blood Flow & Metabolism , 37 (8) pp. 2910-2920. 10.1177/0271678X16679171. Green open access
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Ghosh, A; Kolyva, C; Tachtsidis, I; Highton, D; Elwell, CE; Smith, M; (2013) Reduction of cytochrome C oxidase during vasovagal hypoxia-ischemia in human adult brain: a case study. Advances in Experimental Medicine and Biology , 789 21 - 27. 10.1007/978-1-4614-7411-1_4. Green open access
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Ghosh, A; Tachtsidis, I; Kolyva, C; Highton, D; Elwell, C; Smith, M; (2013) Normobaric hyperoxia does not change optical scattering or pathlength but does increase oxidised cytochrome C oxidase concentration in patients with brain injury. Adv Exp Med Biol , 765 67 - 72. 10.1007/978-1-4614-4989-8_10. Green open access
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Giannoni, Luca; Marradi, Marta; Scibilia, Kevin; Ezhov, Ivan; Bonaudo, Camilla; Artemiou, Angelos; Toaha, Anam; ... Pavone, Francesco Saverio; + view all (2024) Transportable hyperspectral imaging setup based on fast, high-density spectral scanning for in situ quantitative biochemical mapping of fresh tissue biopsies. Journal of Biomedical Optics , 29 (9) , Article 093508. 10.1117/1.JBO.29.9.093508. Green open access
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Giannoni, L; Lange, F; Davies, AL; Dua, A; Gustavson, B; Smith, KJ; Tachtsidis, I; (2018) Hyperspectral Imaging of the Hemodynamic and Metabolic States of the Exposed Cortex: Investigating a Commercial Snapshot Solution. Advances in Experimental Medicine and Biology , 1072 pp. 13-20. 10.1007/978-3-319-91287-5_3. Green open access
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Giannoni, L; Lange, F; Sajic, M; Smith, KJ; Tachtsidis, I; (2021) A hyperspectral imaging system for mapping haemoglobin and cytochrome-c-oxidase concentration changes in the exposed cerebral cortex. IEEE Journal of Selected Topics in Quantum Electronics 10.1109/JSTQE.2021.3053634. (In press). Green open access
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Giannoni, L; Lange, F; Tachtsidis, I; (2020) Investigation of the quantification of hemoglobin and cytochrome-c-oxidase in the exposed cortex with near-infrared hyperspectral imaging: a simulation study. Journal of Biomedical Optics , 25 (4) , Article 046001. 10.1117/1.JBO.25.4.046001. Green open access
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Giannoni, L; Lange, F; Tachtsidis, I; (2018) Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments. Journal of Optics , 20 (4) , Article 044009. 10.1088/2040-8986/aab3a6. Green open access
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Greaves, Dwaynica A; Pinti, Paola; Din, Sara; Hickson, Robert; Diao, Mingyi; Lange, Charlotte; Khurana, Priyasha; ... Hamilton, Antonia FdC; + view all (2022) Exploring Theater Neuroscience: Using Wearable Functional Near-infrared Spectroscopy to Measure the Sense of Self and Interpersonal Coordination in Professional Actors. Journal of Cognitive Neuroscience , 34 (12) pp. 2215-2236. 10.1162/jocn_a_01912. Green open access
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Gunadi, Sonny; Leung, Terence S; Elwell, Clare E; Tachtsidis, Ilias; (2014) Spatial sensitivity and penetration depth of three cerebral oxygenation monitors. Biomedical Optics Express , 5 (9) pp. 2896-2912. 10.1364/BOE.5.002896. Green open access
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Gunasekara, N; Gaeta, G; Levy, A; Boot, E; Tachtsidis, I; (2022) fNIRS neuroimaging in olfactory research: A systematic literature review. Frontiers in Behavioral Neuroscience , 16 , Article 1040719. 10.3389/fnbeh.2022.1040719. Green open access
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Hakim, Uzair; Pinti, Paola; Noah, Adam J; Zhang, Xian; Burgess, Paul; Hamilton, Antonia; Hirsch, Joy; (2022) Investigation of functional near-infrared spectroscopy signal quality and development of the hemodynamic phase correlation signal. Neurophotonics , 9 (2) , Article 025001. 10.1117/1.NPh.9.2.025001. Green open access
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Hapuarachchi, T; Moroz, T; Bainbridge, A; Faulkner, S; Price, D; Broad, KD; Thomas, D; ... Tachtsidis, I; + view all (2014) Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model. Adv Exp Med Biol , 812 187 - 193. 10.1007/978-1-4939-0620-8_25. Green open access
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Hapuarachchi, T; Moroz, T; Bainbridge, A; Price, D; Cady, E; Baer, E; Broad, K; ... Tachtsidis, I; + view all (2013) Modelling blood flow and metabolism in the piglet brain during hypoxia-ischaemia: simulating pH changes. Adv Exp Med Biol , 789 331 - 337. 10.1007/978-1-4614-7411-1_44. Green open access
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Harvey-Jones, K; Lange, F; Tachtsidis, I; Robertson, NJ; Mitra, S; (2021) Role of Optical Neuromonitoring in Neonatal Encephalopathy—Current State and Recent Advances. Frontiers in Pediatrics , 9 , Article 653676. 10.3389/fped.2021.653676. Green open access
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Highton, David; Caldwell, Matthew; Tachtsidis, Ilias; Elwell, Clare E; Smith, Martin; Cooper, Chris E; (2024) The influence of carbon dioxide on cerebral metabolism and oxygen consumption: combining multimodal monitoring with dynamic systems modelling. Biology Open , 13 (1) , Article bio060087. 10.1242/bio.060087. Green open access
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Highton, D; Chitnis, D; Brigadoi, S; Phan, P; Tachtsidis, I; Cooper, R; Everdell, N; ... Elwell, CE; + view all (2018) A Fibreless Multiwavelength NIRS System for Imaging Localised Changes in Cerebral Oxidised Cytochrome C Oxidase. Advances in Experimental Medicine and Biology , 1072 pp. 339-343. 10.1007/978-3-319-91287-5_54. Green open access
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Highton, D; Ghosh, A; Tachtsidis, I; Elwell, C; Smith, M; (2014) Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage. Adv Exp Med Biol , 812 195 - 201. 10.1007/978-1-4939-0620-8_26. Green open access
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Highton, D; Panovska-Griffiths, J; Ghosh, A; Tachtsidis, I; Banaji, M; Elwell, C; Smith, M; (2013) Modelling cerebrovascular reactivity: a novel near-infrared biomarker of cerebral autoregulation? Adv Exp Med Biol , 765 87 - 93. 10.1007/978-1-4614-4989-8_13. Green open access
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Holper, L; Mitra, S; Bale, G; Robertson, N; Tachtsidis, I; (2017) Prediction of brain tissue temperature using near-infrared spectroscopy. NEUROPHOTONICS , 4 (2) 10.1117/1.NPh.4.2.021106. Green open access
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Howard, Rachel; Li, Runci; Harvey-Jones, Kelly; Verma, Vinita; Lange, Frédéric; Boylan, Geraldine; Tachtsidis, Ilias; (2022) Optical Monitoring in Neonatal Seizures. Cells , 11 (16) , Article 2602. 10.3390/cells11162602. Green open access
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Iwata, S; Tachtsidis, I; Takashima, S; Matsuishi, T; Robertson, NJ; Iwata, O; (2014) Dual role of cerebral blood flow in regional brain temperature control in the healthy newborn infant. Int J Dev Neurosci , 37 pp. 1-7. 10.1016/j.ijdevneu.2014.05.010. Green open access
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Jelfs, B; Banaji, M; Tachtsidis, I; Cooper, CE; Elwell, CE; (2012) Modelling noninvasively measured cerebral signals during a hypoxemia challenge: steps towards individualised modelling. PLoS One , 7 (6) , Article e38297. 10.1371/journal.pone.0038297. Green open access
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Kaynezhad, P; Fosbury, R; Hogg, C; Tachtsidis, I; Sivaprasad, S; Jeffery, G; (2022) Near infrared spectroscopy reveals instability in retinal mitochondrial metabolism and haemodynamics with blue light exposure at environmental levels. Journal of Biophotonics , Article e2916. 10.1002/jbio.202100283. (In press). Green open access
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Kaynezhad, Pardis; Jeffery, Glen; Bainbridge, James; Sivaprasad, Sobha; Tachtsidis, Ilias; Hay-Schmidt, Anders; Rajendram, Ranjan; (2022) The Role of Neuroglobin in Retinal Hemodynamics and Metabolism: A Real-Time Study. Translational Vision Science & Technology , 11 (7) , Article 2. 10.1167/tvst.11.7.2. Green open access
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Kaynezhad, P; Mitra, S; Bale, G; Bauer, C; Lingam, I; Meehan, C; Avdic-Belltheus, A; ... Tachtsidis, I; + view all (2019) Quantification of the severity of hypoxic-ischemic brain injury in a neonatal preclinical model using measurements of cytochrome-c-oxidase from a miniature broadband-near-infrared spectroscopy system. Neurophotonics , 6 (4) , Article 045009. 10.1117/1.NPh.6.4.045009. Green open access
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Kaynezhad, P; Tachtsidis, I; Aboelnour, A; Sivaprasad, S; Jeffery, G; (2021) Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration. Scientific Reports , 11 (1) , Article 3274. 10.1038/s41598-021-82811-2. Green open access
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Kaynezhad, P; Tachtsidis, I; Jeffery, G; (2016) Optical monitoring of retinal respiration in real time: 670 nm light increases the redox state of mitochondria. Experimental Eye Research , 152 pp. 88-93. 10.1016/j.exer.2016.09.006. Green open access
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Kirilina, E; Yu, N; Jelzow, A; Wabnitz, H; Jacobs, AM; Tachtsidis, I; (2013) Identifying and quantifying main components of physiological noise in functional near infrared spectroscopy on the prefrontal cortex. Front Hum Neurosci , 7 , Article 864. 10.3389/fnhum.2013.00864. Green open access
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Kolyva, C; Ghosh, A; Tachtsidis, I; Highton, D; Cooper, CE; Smith, M; Elwell, CE; (2014) Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin. Neuroimage , 85 (1) pp. 234-244. 10.1016/j.neuroimage.2013.05.070. Green open access
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Kolyva, C; Ghosh, A; Tachtsidis, I; Highton, D; Smith, M; Elwell, CE; (2013) Dependence on NIRS source-detector spacing of cytochrome c oxidase response to hypoxia and hypercapnia in the adult brain. Advances in Experimental Medicine and Biology Volume , 789 353 - 359. 10.1007/978-1-4614-7411-1_47. Green open access
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Kolyva, C; Kingston, H; Tachtsidis, I; Mohanty, S; Mishra, S; Patnaik, R; Maude, RJ; ... Elwell, CE; + view all (2013) Oscillations in cerebral haemodynamics in patients with falciparum malaria. Adv Exp Med Biol , 765 101 - 107. 10.1007/978-1-4614-4989-8_15. Green open access
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Kovacsova, Z; Bale, G; Mitra, S; Lange, F; Tachtsidis, I; (2021) Absolute quantification of cerebral tissue oxygen saturation with multidistance broadband NIRS in newborn brain. Biomedical Optics Express , 12 (2) p. 907. 10.1364/boe.412088. Green open access
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Lange, F; Verma, V; Harvey-Jones, K; Mitra, S; Tachtsidis, I; (2023) Neonatal Brain Temperature Monitoring Based on Broadband Near-Infrared Spectroscopy. Advances in Experimental Medicine and Biology , 1438 pp. 167-172. 10.1007/978-3-031-42003-0_26. Green open access
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Lange, F; Bale, G; Kaynezhad, P; Pollock, RD; Stevenson, A; Tachtsidis, I; (2020) Broadband NIRS Cerebral Evaluation of the Hemodynamic and Oxidative State of Cytochrome-c-Oxidase Responses to +Gz Acceleration in Healthy Volunteers. Oxygen Transport to Tissue XLI , 1232 pp. 339-345. 10.1007/978-3-030-34461-0_43. Green open access
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Lange, F; Dunne, L; Hale, L; Tachtsidis, I; (2019) MAESTROS: A multi-wavelength time domain NIRS system to monitor changes in oxygenation and oxidation state of cytochrome-c-oxidase. IEEE Journal of Selected Topics in Quantum Electronics , 25 (1) , Article 7100312. 10.1109/JSTQE.2018.2833205. Green open access
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Lange, F; Dunne, L; Tachtsidis, I; (2017) Evaluation of Haemoglobin and Cytochrome Responses During Forearm Ischaemia Using Multi-wavelength Time Domain NIRS. Advances in Experimental Medicine and Biology , 977 pp. 67-72. 10.1007/978-3-319-55231-6_10. Green open access
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Lange, F; Giannoni, L; Tachtsidis, I; (2021) The Use of Supercontinuum Laser Sources in Biomedical Diffuse Optics: Unlocking the Power of Multispectral Imaging. Applied Sciences , 11 (10) p. 4616. 10.3390/app11104616. Green open access
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Lange, F; Tachtsidis, I; (2019) Clinical Brain Monitoring with Time Domain NIRS: A Review and Future Perspectives. [Review]. Applied Sciences , 9 (8) , Article 1612. 10.3390/app9081612. Green open access
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Leung, T.; Tachtsidis, I.; Tisdall, M.; Smith, M.; Delpy, D.; Elwell, C.; (2007) Theoretical investigation of measuring cerebral blood flow in the adult human head using bolus indocyanine green injection and near-infrared spectroscopy. Applied Optics , 46 (10) pp. 1604-1614. Green open access
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Leung, TS; Tachtsidis, I; Tisdall, M; Smith, M; Delpy, DT; Elwell, CE; (2007) Theoretical investigation of measuring cerebral blood flow in the adult human head using bolus Indocyanine Green injection and near-infrared spectroscopy. APPLIED OPTICS , 46 (10) 1604 - 1614. 10.1364/AO.46.001604. Green open access
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Lingam, I; Avdic-Belltheus, A; Meehan, C; Martinello, K; Ragab, S; Peebles, D; Barkhuizen, M; ... Robertson, NJ; + view all (2020) Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia–ischaemia. Pediatric Research 10.1038/s41390-020-0986-3. (In press). Green open access
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Lingam, I; Meehan, C; Avdic-Belltheus, A; Martinello, K; Hristova, M; Kaynezhad, P; Bauer, C; ... Robertson, NJ; + view all (2019) Short-term effects of early initiation of magnesium infusion combined with cooling after hypoxia-ischemia in term piglets. Pediatric Research , 86 pp. 699-708. 10.1038/s41390-019-0511-8. Green open access
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Mai, Guangting; Jiang, Zhizhao; Wang, Xinran; Tachtsidis, Ilias; Howell, Peter; (2024) Neuroplasticity of Speech-in-Noise Processing in Older Adults Assessed by Functional Near-Infrared Spectroscopy (fNIRS). Brain Topography 10.1007/s10548-024-01070-2. (In press). Green open access
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Martinello, KA; Meehan, C; Avdic-Belltheus, A; Lingam, I; Mutshiya, T; Yang, Q; Akin, MA; ... Robertson, NJ; + view all (2021) Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia-ischemia. Pediatric Research 10.1038/s41390-021-01584-6. (In press). Green open access
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Martinello, KA; Meehan, C; Avdic-Belltheus, A; Lingam, I; Ragab, S; Hristova, M; Tann, CJ; ... Robertson, NJ; + view all (2019) Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy. Scientific Reports , 9 (1) , Article 10184. 10.1038/s41598-019-46488-y. Green open access
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Mitra, S; Bale, G; de Roever, I; Meek, J; Robertson, NJ; Tachtsidis, I; (2020) Changes in Brain Tissue Oxygenation and Metabolism During Rewarming After Neonatal Encephalopathy are Related to Electrical Abnormality. Advances in Experimental Medicine and Biology , 1232 pp. 25-31. 10.1007/978-3-030-34461-0_4. Green open access
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Mitra, S; Bale, G; Highton, D; Gunny, R; Uria-Avellanal, C; Bainbridge, A; Sokolska, M; ... Robertson, NJ; + view all (2017) Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury. Journal of Cerebral Blood Flow & Metabolism 10.1177/0271678X17733639. (In press). Green open access
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Mitra, S; Bale, G; Mathieson, S; Uria-Avellanal, C; Meek, J; Tachtsidis, I; Robertson, NJ; (2016) Changes in Cerebral Oxidative Metabolism during Neonatal Seizures Following Hypoxic-Ischemic Brain Injury. Frontiers in Pediatrics , 4 p. 83. 10.3389/fped.2016.00083. Green open access
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Mitra, S; Bale, G; Meek, J; Tachtsidis, I; Robertson, NJ; (2020) Cerebral Near Infrared Spectroscopy Monitoring in Term Infants With Hypoxic Ischemic Encephalopathy—A Systematic Review. Frontiers in Neurology , 11 , Article 393. 10.3389/fneur.2020.00393. Green open access
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Montefinese, M; Pinti, P; Ambrosini, E; Tachtsidis, I; Vinson, D; (2021) Inferior parietal lobule is sensitive to different semantic similarity relations for concrete and abstract words. Psychophysiology , 58 (3) , Article e13750. 10.1111/psyp.13750. Green open access
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Montero-Hernandez, S; Orihuela-Espina, F; Enrique Sucar, L; Pinti, P; Hamilton, A; Burgess, PW; Tachtsidis, I; (2018) Estimating Functional Connectivity Symmetry between Oxy- and Deoxy-Haemoglobin: Implications for fNIRS Connectivity Analysis. Algorithms , 11 (5) , Article 70. 10.3390/a11050070. Green open access
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Moroz, T; Banaji, M; Robertson, NJ; Cooper, CE; Tachtsidis, I; (2012) Computational modelling of the piglet brain to simulate near-infrared spectroscopy and magnetic resonance spectroscopy data collected during oxygen deprivation. Journal of the Royal Society Interface , 9 (72) 1499 - 1509. 10.1098/rsif.2011.0766. Green open access
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Moroz, T; Hapuarachchi, T; Bainbridge, A; Price, D; Cady, E; Baer, E; Tachtsidis, I; ... Cooper, CE; + view all (2013) Modelling blood flow and metabolism in the piglet brain during hypoxia-ischaemia: simulating brain energetics. Adv Exp Med Biol , 789 339 - 344. 10.1007/978-1-4614-7411-1_45. Green open access
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Nardini, D; Toaha, A; Bonaudo, C; Ezhov, I; Artemiou, A; Camelia, M; Nozzoli, F; ... Pavone, F; + view all (2025) Versatile and comprehensive hyperspectral imaging tool for molecular neuronavigation: a case study on cerebral gliomas. Journal of Biomedical Optics , 30 (12) , Article 126007. 10.1117/1.JBO.30.12.126007. Green open access
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Noah, JA; Zhang, X; Dravida, S; DiCocco, C; Suzuki, T; Aslin, RN; Tachtsidis, I; (2021) Comparison of short-channel separation and spatial domain filtering for removal of non-neural components in functional near-infrared spectroscopy signals. Neurophotonics , 8 (1) , Article 015004. 10.1117/1.NPh.8.1.015004. Green open access
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Oliver, D; Tachtsidis, I; Hamilton, AF; (2017) The role of parietal cortex in overimitation: a study with fNIRS. Social Neuroscience , 13 (2) pp. 214-225. 10.1080/17470919.2017.1285812. Green open access
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Papademetriou, M; Tachtsidis, I; Elliott, MJ; Hoskote, A; Elwell, CE; (2013) Wavelet cross-correlation to investigate regional variations in cerebral oxygenation in infants supported on extracorporeal membrane oxygenation. Adv Exp Med Biol , 765 203 - 209. 10.1007/978-1-4614-4989-8_28. Green open access
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Papademetriou, MD; Tachtsidis, I; Elliot, MJ; Hoskote, A; Elwell, CE; (2012) Multichannel near infrared spectroscopy indicates regional variations in cerebral autoregulation in infants supported on extracorporeal membrane oxygenation. J Biomed Opt , 17 (6) , Article 067008. 10.1117/1.JBO.17.6.067008. Green open access
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Phan, PT; Highton, D; Lai, J; Smith, M; Elwell, C; Tachtsidis, I; (2016) Multi-channel multi-distance broadband nearinfrared spectroscopy system to measure the spatial response of cellular oxygen metabolism and tissue oxygenation. Biomedical Optics Express , 7 (11) pp. 4424-4440. 10.1364/BOE.7.004424. Green open access
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Pinti, P; Aichelburg, C; Gilbert, S; Hamilton, A; Hirsch, J; Burgess, P; Tachtsidis, I; (2018) A Review on the Use of Wearable Functional Near-Infrared Spectroscopy in Naturalistic Environments. Japanese Psychological Research , 60 (4) pp. 347-373. 10.1111/jpr.12206. Green open access
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Pinti, P; Aichelburg, C; Lind, F; Power, S; Swingler, E; Merla, A; Hamilton, A; ... Tachtsidis, I; + view all (2015) Using fiberless, wearable fNIRS to monitor brain activity in real-world cognitive tasks. Journal of Visualized Experiments , 106 10.3791/53336. Green open access
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Pinti, P; Devoto, A; Greenhalgh, I; Tachtsidis, I; Burgess, P; Hamilton, A; (2020) The role of anterior prefrontal cortex (area 10) in face-to-face deception measured with fNIRS. Social Cognitive and Affective Neuroscience 10.1093/scan/nsaa086. (In press). Green open access
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Pinti, P; Merla, A; Aichelburg, C; Lind, F; Power, S; Swingler, E; Hamilton, A; ... Tachtsidis, I; + view all (2017) A novel GLM-based method for the Automatic IDentification of functional Events (AIDE) in fNIRS data recorded in naturalistic environments. Neuroimage , 155 pp. 291-304. 10.1016/j.neuroimage.2017.05.001. Green open access
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Pinti, P; Scholkmann, F; Hamilton, A; Burgess, P; Tachtsidis, I; (2019) Current Status and Issues Regarding Pre-processing of fNIRS Neuroimaging Data: An Investigation of Diverse Signal Filtering Methods Within a General Linear Model Framework. Frontiers in Human Neuroscience , 12 , Article 505. 10.3389/fnhum.2018.00505. Green open access
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Pinti, P; Siddiqui, MF; Levy, AD; Jones, EJH; Tachtsidis, I; (2021) An analysis framework for the integration of broadband NIRS and EEG to assess neurovascular and neurometabolic coupling. Scientific Reports , 11 (1) , Article 3977. 10.1038/s41598-021-83420-9. Green open access
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Pinti, P; Tachtsidis, I; Hamilton, A; Hirsch, J; Aichelburg, C; Gilbert, S; Burgess, PW; (2018) The present and future use of functional near‐infrared spectroscopy (fNIRS) for cognitive neuroscience. Annals of the New York Academy of Sciences 10.1111/nyas.13948. (In press). Green open access
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Rajaram, A; Bale, G; Kewin, M; Morrison, LB; Tachtsidis, I; Lawrence, KS; Diop, M; (2018) Simultaneous monitoring of cerebral perfusion and cytochrome c oxidase by combining broadband near-infrared spectroscopy and diffuse correlation spectroscopy. Biomedical Optics Express , 9 (6) pp. 2588-2603. 10.1364/BOE.9.002588. Green open access
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Ricci, Pietro; Bonaudo, Camilla; Ezhov, Ivan; Toaha, Anam; Nardini, Dorotea; Camelia, Manuel; Lucidi, Federica; ... Pavone, Francesco S; + view all (2025) A Label-Free Hyperspectral Imaging Device for Ex Vivo Characterization and Grading of Meningioma Tissues. Journal of Biophotonics , Article e202500374. 10.1002/jbio.202500374. (In press). Green open access
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Russell-Buckland, J; Bale, G; de Roever, I; Tachtsidis, I; (2018) ABroAD: A Machine Learning Based Approach to Detect Broadband NIRS Artefacts. Advances in Experimental Medicine and Biology , 1072 pp. 319-324. 10.1007/978-3-319-91287-5_51. Green open access
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Russell-Buckland, J; Barnes, CP; Tachtsidis, I; (2019) A Bayesian framework for the analysis of systems biology models of the brain. PLoS Computational Biology , 15 (4) , Article e1006631. 10.1371/journal.pcbi.1006631. (In press). Green open access
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Russell-Buckland, J; Caldwell, M; Tachtsidis, I; (2017) WeBCMD: A cross-platform interface for the BCMD modelling framework. Wellcome Open Research , 2 , Article 56. 10.12688/wellcomeopenres.12201.1. Green open access
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Russell-Buckland, J; Kaynezhad, P; Mitra, S; Bale, G; Bauer, C; Lingam, I; Meehan, C; ... Tachtsidis, I; + view all (2021) Systems Biology Model of Cerebral Oxygen Delivery and Metabolism During Therapeutic Hypothermia: Application to the Piglet Model. Advances in Experimental Medicine and Biology , 1269 pp. 31-38. 10.1007/978-3-030-48238-1_5. Green open access
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Russell-Buckland, J; Tachtsidis, I; (2020) Developing a Model to Simulate the Effect of Hypothermia on Cerebral Blood Flow and Metabolism. Oxygen Transport to Tissue XLI , 1232 pp. 299-306. 10.1007/978-3-030-34461-0_38. Green open access
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Scholkmann, Felix; Tachtsidis, Ilias; Wolf, Martin; Wolf, Ursula; (2022) Systemic physiology augmented functional near-infrared spectroscopy: a powerful approach to study the embodied human brain. Neurophotonics , 9 (3) , Article 030801. 10.1117/1.NPh.9.3.030801. Green open access
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Siddiqui, Maheen; Pinti, Paola; Brigadoi, Sabrina; Lloyd-Fox, Sarah; Elwell, Clare E; Johnson, Mark H; Tachtsidis, Ilias; (2023) Using multi-modal neuroimaging to characterise social brain specialisation in infants. eLife , 12 , Article e84122. 10.7554/ELIFE.84122. Green open access
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Siddiqui, MF; Pinti, P; Lloyd-Fox, S; Jones, EJH; Brigadoi, S; Collins-Jones, L; Tachtsidis, I; ... Elwell, CE; + view all (2022) Regional Haemodynamic and Metabolic Coupling in Infants. Frontiers in Human Neuroscience , 15 , Article 780076. 10.3389/fnhum.2021.780076. Green open access
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Siddiqui, MF; Lloyd-Fox, S; Kaynezhad, P; Tachtsidis, I; Johnson, MH; Elwell, CE; (2018) Changes in Cytochrome-C-Oxidase Account for Changes in Attenuation of Near-Infrared Light in the Healthy Infant Brain. Advances in Experimental Medicine and Biology , 1072 pp. 7-12. 10.1007/978-3-319-91287-5_2. Green open access
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Siddiqui, MF; Lloyd-Fox, S; Kaynezhad, P; Tachtsidis, I; Johnson, MH; Elwell, CE; (2017) Non-invasive measurement of a metabolic marker of infant brain function. Scientific Reports , 7 (1330) 10.1038/s41598-017-01394-z. Green open access
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SUDAKOU, A; LANGE, F; ISLER, H; LANKA, P; WOJTKIEWICZ, S; SAWOSZ, P; OSTOJIC, D; ... GEREGA, A; + view all (2021) Time-domain NIRS system based on supercontinuum light source and multi-wavelength detection: Validation for tissue oxygenation studies. Biomedical Optics Express , 12 (10) pp. 6629-6650. 10.1364/BOE.431301. Green open access
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Sudakou, A; Wojtkiewicz, S; Lange, F; Gerega, A; Sawosz, P; Tachtsidis, I; Liebert, A; (2019) Depth-resolved assessment of changes in concentration of chromophores using time-resolved near-infrared spectroscopy: estimation of cytochrome-c-oxidase uncertainty by Monte Carlo simulations. Biomedical Optics Express , 10 (9) p. 4621. 10.1364/boe.10.004621. Green open access
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Tachtsidis, Ilias; (2023) Taking the lid off ambitions for optical imaging of the human brain: a conversation with Clare Elwell. Neurophotonics , 10 (2) , Article 020401. 10.1117/1.NPh.10.2.020401. Green open access
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Tachtsidis, I; Papaioannou, A; (2013) Investigation of frontal lobe activation with fNIRS and systemic changes during video gaming. Adv Exp Med Biol , 789 89 - 95. 10.1007/978-1-4614-7411-1_13. Green open access
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Tachtsidis, I; Scholkmann, F; (2016) False positives and false negatives in functional near-infrared spectroscopy: issues, challenges, and the way forward. Neurophotonics , 3 (3) 031405. 10.1117/1.NPh.3.3.031405. Green open access
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Tachtsidis, I.; Tisdall, M.; Leung, T.S.; Cooper, C.E.; Delpy, D.T.; Smith, M.; Elwell, C.E.; (2007) Investigation of in vivo measurement of cerebral cytochrome-c-oxidase redox changes using near-infrared spectroscopy in patients with orthostatic hypotension. Physiological Measurement , 28 (2) pp. 198-211. 10.1088/0967-3334/28/2/008. Green open access
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Tisdall, M.M.; Tachtsidis, I.; Leung, T.S.; Elwell, C.E.; Smith, M.; (2007) Near infrared spectroscopic quantification of changes in the concentration of oxidized cytochrome oxidase in the healthy human brain during hypoxemia. Journal of Biomedical Optics , 12 (2) 024002-1. 10.1117/1.2718541. Green open access
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Verma, V; Lange, F; Bainbridge, A; Harvey-Jones, K; Robertson, NJ; Tachtsidis, I; Mitra, S; (2022) Brain temperature monitoring in newborn infants: Current methodologies and prospects. Frontiers in Pediatrics , 10 , Article 1008539. 10.3389/fped.2022.1008539. Green open access
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Vezyroglou, Aikaterini; Hebden, Peter; De Roever, Isabel; Thornton, Rachel; Mitra, Subhabrata; Worley, Alan; Alves, Mariana; ... Tachtsidis, Ilias; + view all (2022) Broadband-NIRS System Identifies Epileptic Focus in a Child with Focal Cortical Dysplasia—A Case Study. Metabolites , 12 (3) , Article 260. 10.3390/metabo12030260. Green open access
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Williams, Thomas; Lange, Frederic; Smith, Kenneth J; Tachtsidis, Ilias; Chataway, Jeremy; (2024) Investigating cortical hypoxia in multiple sclerosis via time-domain near-infrared spectroscopy. Annals of Clinical and Translational Neurology 10.1002/acn3.52150. (In press). Green open access
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Yang, Zhiyuan; Lange, Frédéric; Xia, Yiqing; Chertavian, Casey; Cabolis, Katerina; Sajic, Marija; Werring, David J; ... Smith, Kenneth J; + view all (2024) Nimodipine Protects Vascular and Cognitive Function in an Animal Model of Cerebral Small Vessel Disease. Stroke , 55 (7) pp. 1914-1922. 10.1161/STROKEAHA.124.047154. Green open access
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Yücel, MA; Lühmann, AV; Scholkmann, F; Gervain, J; Dan, I; Ayaz, H; Boas, D; ... Wolf, M; + view all (2021) Errata: Best practices for fNIRS publications. Neurophotonics , 8 (1) , Article 019802. 10.1117/1.NPh.8.1.019802. Green open access
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Yücel, MA; Lühmann, AV; Scholkmann, F; Gervain, J; Dan, I; Ayaz, H; Boas, D; ... Wolf, M; + view all (2021) Best practices for fNIRS publications. Neurophotonics , 8 (1) , Article 012101. 10.1117/1.NPh.8.1.012101. Green open access
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Book chapter

Bale, G; Tachtsidis, I; (2019) The Use of Near‐Infrared Spectroscopy to Monitor Tissue Oxygenation, Metabolism and Injury in Low Resource Settings. In: Atkinson, K and Mabey, D, (eds.) Revolutionizing Tropical Medicine: Point-of-Care Tests, New Imaging Technologies and Digital Health. (pp. 344-359). Wiley-Blackwell: Hoboken, NJ, USA.

Ghosh, A; Tachtsidis, I; Kolyva, C; Cooper, CE; Smith, M; Elwell, CE; (2012) Use of a hybrid optical spectrometer for the measurement of changes in oxidized cytochrome c oxidase concentration and tissue scattering during functional activation. In: Wolf, M and Bucher, HU and Rudin, M and Van Huffel, S and Wolf, U and Bruley, DF and Harrison, DK, (eds.) Oxygen Transport to Tissue XXXIII. (119 - 124). Springer: New York, US. Green open access
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Kovacsova, Z; Bale, G; Mitra, S; de Roever, I; Meek, J; Robertson, N; Tachtsidis, I; (2018) Investigation of Confounding Factors in Measuring Tissue Saturation with NIRS Spatially Resolved Spectroscopy. In: Thews, O and LaManna, JC and Harrison, DK, (eds.) Oxygen Transport to Tissue XL. (pp. 307-312). Springer Nature: Cham, Switzerland. Green open access
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Mitra, S; Bale, G; Meek, J; Mathieson, S; Uria, C; Kendall, G; Robertson, NJ; (2016) In Vivo Measurement of Cerebral Mitochondrial Metabolism Using Broadband Near Infrared Spectroscopy Following Neonatal Stroke. In: Elwell, CE and Leung, TS and Harrison, DK, (eds.) Oxygen Transport to Tissue XXXVII. (pp. 493-499). Springer New York: New York, NY, USA. Green open access
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Tachtsidis, I; Kovacsova, Z; Bale, G; (2018) Medical Utility of NIR Monitoring. In: Encyclopedia of Biomedical Engineering. (pp. 415-431). Elsevier

Proceedings paper

Artemiou, A; Lange, F; Caredda, C; Giannoni, L; Montcel, B; Tachtsidis, I; (2025) A liquid phantom for validating hyperspectral imaging in brain tumour resection. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Progress in Biomedical Optics and Imaging Proceedings of SPIE. (pp. p. 50). SPIE: Munich, Germany. Green open access
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Bale, G; Mitra, S; de Roever, I; Chan, M; Caicedo-Dorado, A; Meek, J; Robertson, N; (2016) Interrelationship Between Broadband NIRS Measurements of Cerebral Cytochrome C Oxidase and Systemic Changes Indicates Injury Severity in Neonatal Encephalopathy. In: Luo, Q and Li, L and Harrison, D and Shi, H and Bruley, D, (eds.) Oxygen Transport to Tissue XXXVIII. Advances in Experimental Medicine and Biology,. (pp. pp. 181-186). Springer: Cham. Green open access
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Bale, G; Rajaram, A; Kewin, M; Morrison, L; Bainbridge, A; Liu, L; Anazodo, U; ... Tachtsidis, I; + view all (2019) Multimodal measurements of brain tissue metabolism and perfusion in a neonatal model of hypoxic-ischaemic injury. In: Dehghani, H and Wabnitz, H, (eds.) Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Banaji, M; Mallet, A; Elwell, CE; Nicholls, P; Tachtsidis, I; Smith, M; Cooper, CE; (2010) Modelling of Mitochondrial Oxygen Consumption and NIRS Detection of Cytochrome Oxidase Redox State. In: Takahashi, E and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXI. (pp. 285 - 291). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Bili, Danai; Lange, Frédéric; Jones, Kelly H; Parfentyeva, Veronika; Durduran, Turgut; Robertson, Nikki; Mitra, Subhabrata; (2023) Classification of brain injury severity using a hybrid broadband NIRS and DCS instrument with a machine learning approach. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings Volume 12628, Diffuse Optical Spectroscopy and Imaging IX. (pp. 126280D). SPIE: Munich, Germany. Green open access
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Caredda, Charly; Ezhov, Ivan; Sdika, Michaël; Lange, Frederic; Giannoni, Luca; Tachtsidis, Ilias; Montcel, Bruno; (2024) Pixel-wise and real-time estimation of optical mean path length using deep learning: application for intraoperative functional brain mapping. In: Elson, Daniel S and Gioux, Sylvain and Pogue, Brian W, (eds.) Proceedings Volume 13009:Clinical Biophotonics III. (pp. 130090F-1-130090F-4). SPIE: Bellingham, WA, USA. Green open access
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Caredda, Charly; Lange, Frederic; Giannoni, Luca; Ezhov, Ivan; Tachtsidis, Ilias; Montcel, Bruno; (2024) A digital instrument simulator to optimize the development of hyperspectral systems for intraoperative brain mapping. In: Tuchin, Valery V and Blondel, Walter CPM and Zalevsky, Zeev, (eds.) Proceedings Volume 13010, Tissue Optics and Photonics III. (pp. 130100L-1-130100L-5). SPIE: Bellingham, WA, USA. Green open access
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Caredda, Charly; Lange, Frédéric; Tachtsidis, Ilias; Montcel, Bruno; (2023) Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings of SPIE Volume 12628 - The International Society for Optical Engineering. (pp. 126280Q). SPIE: Munich, Germany. Green open access
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De Roever, I; Vezyroglou, A; Hebden, P; Thornton, R; Worley, A; Alves, M; Dean, E; ... Tachtsidis, I; + view all (2019) A new multichannel broadband NIRS system for quantitative monitoring of brain hemodynamics and metabolism during seizures. In: Dehghani, H and Wabnitz, H, (eds.) Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Ezhov, I; Giannoni, L; Shit, S; Lange, F; Kofler, F; Menze, B; Tachtsidis, I; (2023) Identifying chromophore fingerprints of brain tumor tissue on hyperspectral imaging using principal component analysis. In: Proceedings Volume 12628, Diffuse Optical Spectroscopy and Imaging IX; 1262826 (2023). SPIE: Munich, Germany. Green open access
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Fischer, JB; Kobayashi Frisk, L; Tachtsidis, I; Delgado Mederos, R; Mayos Pèrez, M; Scholkmann, F; Durduran, T; (2021) Does wearing a non-medical face mask cause changes in cerebral hemodynamics? In: Proceedings of SPIE: Diffuse Optical Spectroscopy and Imaging VIII. SPIE Green open access
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Gao, L; Elwell, CE; Kohl-Bareis, M; Gramer, M; Cooper, CE; Leung, TS; Tachtsidis, I; (2011) Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements Using NIRS during a Valsalva Manoeuvre. In: LaManna, JC and Puchowicz, MA and Xu, K and Harrison, DK and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXII. (pp. 15 - 20). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Giannoni, L; Lange, F; Sajic, M; Smith, KJ; Tachtsidis, I; (2021) hNIR: A hyperspectral imaging system for mapping changes in haemoglobin and cytochrome-c-oxidase on the exposed cerebral cortex of mice. In: Proceedings Biophotonics Congress 2021. Optica Publishing Group Green open access
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Giannoni, L; Toaha, A; Marradi, M; Degl’Innocenti, DR; Ezhov, I; Caredda, C; Gautheron, A; ... Pavone, FS; + view all (2024) HyperProbe consortium: transforming neuronavigation in glioma surgery with hyperspectral imaging. In: Proceedings of the Optica Biophotonics Congress: Biomedical Optics 2024 (Translational, Microscopy, OCT, OTS, BRAIN). (pp. 1-2 [AAM]). Optica Green open access
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Giannoni, L; Toaha, A; Marradi, M; Ricci, P; Degl'Innocenti, DR; Ezhov, I; Caredda, C; ... Pavone, FS; + view all (2025) HyperProbe consortium: transforming tumour neurosurgery with innovative hyperspectral imaging. In: Kainerstorfer, Jana M and Buckley, Erin M and Srinivasan, Vivek J, (eds.) Progress in Biomedical Optics and Imaging - Proceedings of SPIE. (pp. p. 4). SPIE: San Francisco, California, United States. Green open access
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Giannoni, Luca; Marradi, Marta; Marchetti, Marco; Degl'Innocenti, Duccio R; Ezhov, Ivan; Caredda, Charly; Gautheron, Arthur; ... Pavone, Francesco S; + view all (2023) HyperProbe consortium: innovate tumour neurosurgery with innovative photonic solutions. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings of SPIE Vol. 12628 - The International Society for Optical Engineering. (pp. 126281C). SPIE: Munich, Germany. Green open access
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Giannoni, Luca; Talati, Musa; Gopal, Darshana; Hakim, Uzair; Artemiou, Angelos; Lange, Frédéric; Mitra, Subhabrata; (2025) Standardised testing procedure based on optical phantoms for validation of photonics instrumentation aimed at clinical monitoring of the placenta. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings: Diffuse Optical Spectroscopy and Imaging X. (pp. 13935 1B). SPIE: Munich, Germany. Green open access
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Giannoni, L; Lange, F; Tachtsidis, I; (2019) A near-infrared hyperspectral imaging system for quantitative monitoring of hemodynamics and metabolism on the exposed cortex of mice. In: Dehghani, H and Wabnitz, H, (eds.) Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Gopal, D; Talati, M; Ranaei-Zamani, N; Giannoni, L; Hakim, U; Kowobari, O; Newth, O; ... Tachtsidis, I; + view all (2025) Cloud-based automated system for NIRS data processing. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Progress in Biomedical Optics and Imaging Proceedings of SPIE. (pp. p. 44). SPIE: Munich, Germany. Green open access
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Hartenberger, Martin; Ayaz, Huzeyfe; Ozlugedik, Fatih; Caredda, Charly; Giannoni, Luca; Lange, Frédéric; Lux, Laurin; ... Ezhov, Ivan; + view all (2026) Redefining Spectral Unmixing for In-Vivo Brain Tissue Analysis from Hyperspectral Imaging. In: Li, Chao and Qin, Wenjian and Wu, Jia and Zaki, Nazar, (eds.) Computational Mathematics Modeling in Cancer Analysis, Proceedings. (pp. pp. 40-49). Springer, Cham: Cham, Switzerland. (In press).

Herrera-Vega, J; Montero-Hernández, S; Tachtsidis, I; Treviño-Palacios, CG; Orihuela-Espina, F; (2017) Modelling and validation of diffuse reflectance of the adult human head for fNIRS: Scalp sub-layers definition. In: 13th International Conference on Medical Information Processing and Analysis. (pp. 1057206-1-1057206-8). SPIE Green open access
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Highton, J; Lange, F; Talati, M; Airantzis, D; Ilwuke, T; Hakim, U; Chitnis, D; ... Tachtsidis, I; + view all (2025) Measurement of placental depth during time domain NIRS using deep learning. In: Fantini, Sergio and Taroni, Paola, (eds.) Progress in Biomedical Optics and Imaging - Proceedings of SPIE. (pp. p. 26). SPIE Green open access
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Jelzow, A; Tachtsidis, I; Kirilina, E; Niessing, M; Bruhl, R; Wabnitz, H; Heine, A; ... Macdonald, R; + view all (2011) Simultaneous measurement of time-domain fNIRS and physiological signals during a cognitive task. In: Hielscher, AH and Taroni, P, (eds.) DIFFUSE OPTICAL IMAGING III. SPIE-INT SOC OPTICAL ENGINEERING: Washington, US. Green open access
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Kovácsová, Z; Bale, G; Veesa, JD; Dehghani, H; Tachtsidis, I; (2019) A broadband multi-distance approach to measure tissue oxygen saturation with continuous wave near-infrared spectroscopy. In: Dehghani, H and Wabnitz, H, (eds.) Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Lange, F; Li, X; Frisk, LK; Durduran, T; Tachtsidis, I; (2025) Optimizing deep tissue monitoring with diffuse optics: virtual tools for TD-NIRS and TD-SCOS development. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Progress in Biomedical Optics and Imaging Proceedings of SPIE. (pp. p. 70). SPIE: Munich, Germany. Green open access
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Lange, F; Williams, T; Chataway, J; Smith, KJ; Tachtsidis, I; (2021) Cerebral time domain near-infrared spectroscopy of people with multiple sclerosis: A feasibility study. In: Proceedings of SPIE: Diffuse Optical Spectroscopy and Imaging VIII. SPIE Green open access
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Lange, F; Williams, T; Chataway, J; Smith, KJ; Tachtsidis, I; (2021) Cerebral time domain near-infrared spectroscopy of people with multiple sclerosis: A feasibility study. In: European Conferences on Biomedical Optics 2021 (ECBO). (pp. ETu3C.6). Optical Society of America (OSA): Munich, Germany. Green open access
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Lange, Frédéric; Giannoni, Luca; Fort, Fernand; Caredda, Charly; Montcel, Bruno; Tachtsidis, Ilias; (2023) A digital instrument simulator to optimize the development of a hyperspectral imaging system for neurosurgery. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings of SPIE - The International Society for Optical Engineering. (pp. 126282C). SPIE: Munich, Germany. Green open access
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Lange, F; Tachtsidis, I; (2019) Short and mid-term reproducibility analysis of cerebral tissue saturation measured by time domain-NIRS. In: Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Lanka, P; Yang, L; Orive-Miguel, D; Veesa, JD; Tagliabue, S; Sudakou, A; Samaei, S; ... Pifferi, A; + view all (2021) A multi-laboratory comparison of photon migration instruments and their performances – the BitMap Exercise. In: Proceedings of SPIE - Optical Tomography and Spectroscopy of Tissue XIV. SPIE Green open access
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Lanka, P; Yang, L; Orive-Miguel, D; Veesa, JD; Tagliabue, S; Sudakou, A; Samaei, S; ... Pifferi, A; + view all (2019) The BITMAP exercise: a multi-laboratory performance assessment campaign of diffuse optical instrumentation. In: Dehghani, H and Wabnitz, H, (eds.) Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Li, X; Lange, F; Sudakou, A; Tachtsidis, I; (2025) Can we accurately retrieve oxyhaemoglobin concentration at 1064nm with TD-NIRS?: a Monte Carlo simulation study. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Progress in Biomedical Optics and Imaging Proceedings of SPIE. (pp. p. 64). SPIE: Munich, Germany. Green open access
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Mitra, S; Bale, G; Meek, J; Uria-Avellanal, C; Robertson, NJ; Tachtsidis, I; (2016) Relationship Between Cerebral Oxygenation and Metabolism During Rewarming in Newborn Infants After Therapeutic Hypothermia Following Hypoxic-Ischemic Brain Injury. In: Oxygen Transport to Tissue XXXVIII. (pp. pp. 245-251). Springer: Cham. Green open access
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Moroz, T; Banaji, M; Tisdall, M; Cooper, CE; Elwell, CE; Tachtsidis, I; (2012) Development of a model to aid NIRS data interpretation: results from a hypercapnia study in healthy adults. In: Wolf, M and Bucher, HU and Rudin, M and Van Huffel, S and Wolf, U and Bruley, DF and Harrison, DK, (eds.) Oxygen Transport to Tissue XXXIII. (pp. 293 - 300). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Orive-Miguel, D; Lanka, P; Yang, L; Tagliabue, S; Sudakou, A; Samaei, S; Veesa, JD; ... Pifferi, A; + view all (2019) The BitMap dataset: an open dataset on performance assessment of diffuse optics instruments. In: Dehghani, H and Wabnitz, H, (eds.) Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Papademetriou, MD; Tachtsidis, I; Banaji, M; Elliott, MJ; Hoskote, A; Elwell, CE; (2012) Optical topography to measure variations in regional cerebral oxygenation in an infant supported on veno-arterial extra-corporeal membrane oxygenation. In: Wolf, M and Bucher, HU and Rudin, M and Van Huffel, S and Wolf, U and Bruley, DF and Harrison, DK, (eds.) Oxygen Transport to Tissue XXXIII. (pp. 71 - 76). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Papademetriou, MD; Tachtsidis, I; Leung, TS; Elliott, MJ; Hoskote, A; Elwell, CE; (2010) Cerebral and Peripheral Tissue Oxygenation in Children Supported on ECMO for Cardio-Respiratory Failure. In: Takahashi, E and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXI. (pp. 447 - 453). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Patel, S; Katura, T; Maki, A; Tachtsidis, I; (2011) Quantification of Systemic Interference in Optical Topography Data during Frontal Lobe and Motor Cortex Activation: An Independent Component Analysis. In: LaManna, JC and Puchowicz, MA and Xu, K and Harrison, DK and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXII. (pp. 45 - 51). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Rajaram, Ajay; Bale, Gemma; Kewin, Matthew; Tachtsidis, Ilias; Lawrence, Keith; Diop, Mamadou; (2018) Hybrid broadband NIRS/Diffuse correlation spectroscopy system for simultaneous monitoring of cerebral perfusion and cytochrome c oxidase. In: Clinical and Translational Biophotonics in Proceedings Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS). The Optical Society: Hollywood, Florida, United States. Green open access
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Ricci, P; Bonaudo, C; Ezhov, I; Toaha, A; Nardini, D; Chessel, L; Giannoni, L; ... Pavone, FS; + view all (2025) A Hyperspectral Imaging System for Meningioma Grade Discrimination. In: Lilge, Lothar D and Huang, Zhiwei, (eds.) Progress in Biomedical Optics and Imaging Proceedings of SPIE. (pp. p. 126). SPIE: Munich, Germany. Green open access
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Siddiqui, MF; Brigadoi, S; Collins-Jones, L; Lloyd-Fox, S; Jones, EJH; Tachtsidis, I; Johnson, MH; (2022) Imaging Cerebral Energy Metabolism in Healthy Infants. In: Scholkmann, F and LaManna, J and Wolf, U, (eds.) Oxygen Transport to Tissue XLIII. (pp. pp. 9-15). Springer: Cham, Switzerland. Green open access
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Sudakou, A; Lange, F; Isler, H; Gerega, A; Ostojic, D; Sawosz, P; Tachtsidis, I; ... Liebert, A; + view all (2019) Multi-wavelength time-resolved NIRS measurements for estimation of absolute concentration of chromophores: blood phantom study. In: Diffuse Optical Spectroscopy and Imaging VII. SPIE: Munich, Germany. Green open access
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Tachtsidis, I; Lange, F; Pinti, P; Bale, G; Sokolska, M; Avdic-Belltheus, A; Meehan, C; ... Mitra, S; + view all (2021) An optical biomarker of hypoxic-ischaemic injury severity in the neonatal brain. In: Proceedings of SPIE: Diffuse Optical Spectroscopy and Imaging VIII. SPIE Green open access
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Tachtsidis, I; Lange, F; Pintia, P; Balea, G; Sokolska, M; Avdic-Belltheus, A; Meehan, C; ... Mitra, S; + view all (2021) An optical biomarker of hypoxic-ischaemic injury severity in the neonatal brain. In: European Conferences on Biomedical Optics 2021 (ECBO). (pp. ETu1C.3). Optical Society of America (OSA): Munich, Germany. Green open access
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Tachtsidis, I; Gao, L; Leung, TS; Kohl-Bareis, M; Cooper, CE; Elwell, CE; (2010) A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum. In: Takahashi, E and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXI. (pp. 169 - 175). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Tachtsidis, I; Koh, PH; Stubbs, C; Elwell, CE; (2010) Functional Optical Topography Analysis Using Statistical Parametric Mapping (SPM) Methodology with and without Physiological Confounds. In: Takahashi, E and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXI. (pp. 237 - 243). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Tachtsidis, I; Tisdall, MM; Pritchard, C; Leung, TS; Ghosh, A; Elwell, CE; Smith, M; (2011) Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome-c-Oxidase in Traumatic Brain Injury Patients during Hypercapnoea A Broadband NIRS Study. In: LaManna, JC and Puchowicz, MA and Xu, K and Harrison, DK and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXII. (pp. 9 - 14). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access
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Talati, M; Illukwe, T; Airantzis, D; Gopal, D; Chitnis, D; Hakim, U; Highton, J; ... Tachtsidis, I; + view all (2025) FetalSenseM: a multiwavelength near-infrared spectroscopy device for in vivo oxygenation and metabolism measurements. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Proceedings Volume 13935, Diffuse Optical Spectroscopy and Imaging X; 139352X (2025). (pp. p. 62). SPIE: Munich, Germany. Green open access
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Talati, M; Lange, F; Tachtsidis, I; (2023) Testing novel miniature NIR spectrometers for wearable broadband NIRS devices. In: Proceedings of SPIE - The International Society for Optical Engineering. SPIE: Munich, Germany. Green open access
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Toaha, A; Ricci, P; Chessel, L; Nardini, D; Giannoni, L; Tachtsidis, I; Pavone, F; (2025) Advancing neuroscience diagnostics: a hyperspectral imaging system for real-time biochemical insights into brain tissue. In: Contini, Davide and Hoshi, Yoko and O'Sullivan, Thomas D, (eds.) Progress in Biomedical Optics and Imaging Proceedings of SPIE. (pp. p. 60). SPIE Green open access
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Conference item

Lanka, P; Yang, L; Orive-Miguel, D; Veesa, JD; Tagliabue, S; Sudakou, A; Samaei, S; ... Pifferi, A; + view all (2020) Multi-laboratory efforts for the standardization of performance assessment of diffuse optics instruments - The BitMap Exercise. Presented at: Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN, Washington, DC, USA. Green open access
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Poster

Ronca, F; Crum, J; Jones, I; Hirsch, J; Hamilton, A; Tachtsidis, I; Burgess, P; (2021) Extensive Prefrontal Cortex Haemodynamic Changes Provoked By Intense Aerobic Exercise, Measured Via FNIRS. Presented at: ACSM 68th Annual Meeting 2021, Virtual conference. Green open access
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Thesis

Bale, GM; (2016) Development of optical instrumentation and methods to monitor brain oxygen metabolism: application to neonatal brain injury. Doctoral thesis , UCL (University College London). Green open access
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Dunne, LT; (2016) Development of a Novel Multiwavelength, Time Resolved, Near Infrared Spectrometer. Doctoral thesis , UCL (University College London). Green open access
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Kaynezhad, Pardis; (2018) Miniature Broadband-NIRS System to Measure CNS Tissue Oxygenation and Metabolism in Preclinical Research. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Phan, Phong Thanh; (2018) Development of a multi-distance, multi-channel broadband near-infrared spectroscopy system to investigate the spatial variation in cellular oxygen metabolism in the healthy and injured adult human brains. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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Tachtsidis, I; (2005) Experimental measurements of cerebral haemodynamics and oxygenation and comparisons with a computational model: a near-infrared sprectroscopy investigation. Doctoral thesis , University College London.

This list was generated on Sun Feb 1 10:25:51 2026 GMT.