Gunadi, S; Leung, TS; Elwell, CE; Tachtsidis, I; (2014) Spatial sensitivity and penetration depth of three cerebral oxygenation monitors. Biomed Opt Express , 5 (9) pp. 2896-2912. 10.1364/BOE.5.002896.

Text Gunadi-2014-Spatial sensitivity.pdf Access restricted to UCL open access staff Download (1MB)

Abstract

The spatial sensitivities of NIRO-100, ISS Oximeter and TRS-20 cerebral oxygenation monitors are mapped using the local perturbation method to inform on their penetration depths and susceptibilities to superficial contaminations. The results show that TRS-20 has the deepest mean penetration depth and is less sensitive than the other monitors to a localized absorption change in the superficial layer. However, an integration time of more than five seconds is required by the TRS-20 to achieve an acceptable level of signal-to-noise ratio, which is the poorest amongst the monitors. With the exception of NIRO-100 continuous wave method, the monitors are not significantly responsive to layer-wide absorption change that occurs in the superficial layer.

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