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Spatial sensitivity and penetration depth of three cerebral oxygenation monitors.

Gunadi, S; Leung, TS; Elwell, CE; Tachtsidis, I; (2014) Spatial sensitivity and penetration depth of three cerebral oxygenation monitors. Biomed Opt Express , 5 (9) pp. 2896-2912. 10.1364/BOE.5.002896. Gold open access

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Abstract

The spatial sensitivities of NIRO-100, ISS Oximeter and TRS-20 cerebral oxygenation monitors are mapped using the local perturbation method to inform on their penetration depths and susceptibilities to superficial contaminations. The results show that TRS-20 has the deepest mean penetration depth and is less sensitive than the other monitors to a localized absorption change in the superficial layer. However, an integration time of more than five seconds is required by the TRS-20 to achieve an acceptable level of signal-to-noise ratio, which is the poorest amongst the monitors. With the exception of NIRO-100 continuous wave method, the monitors are not significantly responsive to layer-wide absorption change that occurs in the superficial layer.

Type: Article
Title: Spatial sensitivity and penetration depth of three cerebral oxygenation monitors.
Location: United States
Open access status: An open access publication
DOI: 10.1364/BOE.5.002896
Publisher version: http://dx.doi.org/10.1364/BOE.5.002896
Language: English
Additional information: © 2014 Optical Society of America
Keywords: (170.0170) Medical optics and biotechnology, (170.3660) Light propagation in tissues, (170.3890) Medical optics instrumentation
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1443511
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