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A multi-laboratory comparison of photon migration instruments and their performances – the BitMap Exercise

Lanka, P; Yang, L; Orive-Miguel, D; Veesa, JD; Tagliabue, S; Sudakou, A; Samaei, S; ... Pifferi, A; + view all (2021) A multi-laboratory comparison of photon migration instruments and their performances – the BitMap Exercise. In: Proceedings of SPIE - Optical Tomography and Spectroscopy of Tissue XIV. SPIE Green open access

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Abstract

Performance assessment and standardization are indispensable for instruments of clinical relevance in general and clinical instrumentation based on photon migration/diffuse optics in particular. In this direction, a multi-laboratory exercise was initiated with the aim of assessing and comparing their performances. 29 diffuse optical instruments belonging to 11 partner institutions of a European level Marie Curie Consortium BitMap1 were considered for this exercise. The enrolled instruments covered different approaches (continuous wave, CW; frequency domain, FD; time domain, TD and spatial frequency domain imaging, SFDI) and applications (e.g. mammography, oximetry, functional imaging, tissue spectroscopy). 10 different tests from 3 well-accepted protocols, namely, the MEDPHOT2, the BIP3, and the nEUROPt4 protocols were chosen for the exercise and the necessary phantoms kits were circulated across labs and institutions enrolled in the study. A brief outline of the methodology of the exercise is presented here. Mainly, the design of some of the synthetic descriptors, (single numeric values used to summarize the result of a test and facilitate comparison between instruments) for some of the tests will be discussed.. Future actions of the exercise aim at deploying these measurements onto an open data repository and investigating common analysis tools for the whole dataset.

Type: Proceedings paper
Title: A multi-laboratory comparison of photon migration instruments and their performances – the BitMap Exercise
Event: SPIE BiOS 2021
ISBN-13: 9781510641136
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2578521
Publisher version: https://doi.org/10.1117/12.2578521
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Performance assessment, standardization, diffuse optics, near-infrared, phantom, absorption, scattering
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10129961
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