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A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum

Tachtsidis, I; Gao, L; Leung, TS; Kohl-Bareis, M; Cooper, CE; Elwell, CE; (2010) A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum. In: Takahashi, E and Bruley, DF, (eds.) Oxygen Transport to Tissue XXXI. (pp. 169 - 175). Springer Verlag: Berlin/ Heidelberg, Germany. Green open access

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Abstract

For resolving absolute concentration of tissue chromophores in the human adult brain with near-infrared spectroscopy it is necessary to calculate the light scattering and absorption, at multiple wavelengths with some depth resolution. To achieve this we propose an instrumentation configuration that combines multi-distance frequency and broadband spectrometers to quantify chromophores in turbid media by using a hybrid spatially resolved algorithm. Preliminary results in solid phantoms as well as liquid dynamic homogeneous and inhomogeneous phantoms and in-vivo muscle measurements showed encouraging results.

Type: Proceedings paper
Title: A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum
Event: 36th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT)
Location: Sapporo, JAPAN
Dates: 3 - 7 August, 2008
ISBN-13: 9781441912398
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-1-4419-1241-1_24
Publisher version: http://dx.doi.org/10.1007/978-1-4419-1241-1_24
Language: English
Additional information: © 2010 Springer Verlag. The original publication is available at www.springerlink.com
Keywords: Spectroscopy
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/75763
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