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Article

Aalto, AL; Mohan, AK; Schwintzer, L; Kupka, S; Kietz, C; Walczak, H; Broemer, M; (2018) M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila. Cell Death & Differentiation 10.1038/s41418-018-0164-x. (In press). Green open access
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Abbosh, C; Swanton, C; Birkbak, NJ; (2018) Circulating tumor DNA analyses reveal novel resistance mechanisms to CDK inhibition in metastatic breast cancer. Annals of Oncology 10.1093/annonc/mdy017. (In press). Green open access
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Abdollah, MRA; Carter, TJ; Jones, C; Kalber, TL; Rajkumar, V; Tolner, B; Gruettner, C; ... Chester, KA; + view all (2018) Fucoidan Prolongs the Circulation Time of Dextran-Coated Iron Oxide Nanoparticles. ACS Nano , 12 (2) pp. 1156-1169. 10.1021/acsnano.7b06734. Green open access
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Abdul-Aziz, AM; Shafat, MS; Sun, Y; Marlein, CR; Piddock, RE; Robinson, SD; Edwards, DR; ... Rushworth, SA; + view all (2018) HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia. Oncogene , 37 (20) pp. 2676-2686. 10.1038/s41388-018-0151-1. Green open access
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Abou-Alfa, G; Qin, S; Ryoo, B-Y; Lu, S-N; Yen, C-J; Feng, Y-H; Lim, HY; ... Chen, L-T; + view all (2018) Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma. Annals of Oncology , 29 (6) pp. 1402-1408. 10.1093/annonc/mdy101. Green open access
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Abou-Alfa, GK; Meyer, T; Cheng, A-L; El-Khoueiry, AB; Rimassa, L; Ryoo, B-Y; Cicin, I; ... Kelley, RK; + view all (2018) Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma. New England Journal of Medicine , 379 (1) pp. 54-63. 10.1056/NEJMoa1717002. Green open access
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Adams, R; Brown, E; Brown, L; Butler, R; Falk, S; Fisher, D; Kaplan, R; ... FOCUS4 Trial Investigators; + view all (2018) Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial. The Lancet Gastroenterology & Hepatology , 3 (3) pp. 162-171. 10.1016/S2468-1253(17)30394-1. Green open access
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Agerbæk, MØ; Bang-Christensen, SR; Yang, M-H; Clausen, TM; Pereira, MA; Sharma, S; Ditlev, SB; ... Salanti, A; + view all (2018) The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner. Nature Communications , 9 (1) , Article 3279. 10.1038/s41467-018-05793-2. Green open access
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Aguiar, P; Azevedo, O; Pinto, R; Marino, J; Cardoso, C; Sousa, N; Cunha, D; ... Ducla Soares, JL; + view all (2018) Biomarkers of Myocardial Fibrosis: Revealing the Natural History of Fibrogenesis in Fabry Disease Cardiomyopathy. Journal of the American Heart Association , 7 (6) 10.1161/JAHA.117.007124. Green open access
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Al Shareef, Zainab; Kardooni, Hoda; Murillo-Garzón, Virginia; Domenici, Giacomo; Stylianakis, Emmanouil; Steel, Jennifer H; Rabano, Miriam; ... Kypta, Robert M; + view all (2018) Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1. Oncogene , 37 pp. 5305-5324. 10.1038/s41388-018-0294-0. Green open access
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Alberro, JA; Ballester, B; Deulofeu, P; Fabregas, R; Fraile, M; Gubern, JM; Janer, J; ... Llombart, HA; + view all (2018) Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials. The Lancet Oncology , 19 (1) pp. 27-39. 10.1016/S1470-2045(17)30777-5. Green open access
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Alexandrou, C; Al-Aqbi, SS; Higgins, JA; Boyle, W; Karmokar, A; Andreadi, C; Luo, J-L; ... Rufini, A; + view all (2018) Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes. Scientific Reports , 8 , Article 12096. 10.1038/s41598-018-30591-7. Green open access
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Alrifai, D; Forster, MD; Janes, SM; (2018) Emerging resistance pathways in lung cancer: what has ROS-1 taught us? [Editorial comment]. Translational Lung Cancer Research , 7 (Suppl 1) S9-S12. 10.21037/tlcr.2017.11.13. Green open access
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Amos, R; Bulbeck, H; Burnet, N; Crellin, A; Eaton, D; Evans, P; Hall, E; ... Sharma, RA; + view all (2018) Proton Beam Therapy – the Challenges of Delivering High-quality Evidence of Clinical Benefit. Clinical Oncology , 30 (5) 10.1016/j.clon.2018.02.031. Green open access
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Anderson, ND; de Borja, R; Young, MD; Fuligni, F; Rosic, A; Roberts, ND; Hajjar, S; ... Shlien, A; + view all (2018) Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors. Science , 361 (6405) 10.1126/science.aam8419. Green open access
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Anderson, RA; Remedios, R; Kirkwood, AA; Patrick, P; Stevens, L; Clifton-Hadley, L; Roberts, T; ... Johnson, PWM; + view all (2018) Determinants of Ovarian Function After Response-adapted Therapy in Patients With Advanced Hodgkin's Lymphoma (RATHL): a Secondary Analysis of a Randomised Phase 3 Trial. Lancet Oncology , 19 (10) pp. 1328-1337. 10.1016/S1470-2045(18)30500-X. Green open access
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Arends, M; Biegstraaten, M; Wanner, C; Sirrs, S; Mehta, A; Elliott, PM; Oder, D; ... Hollak, CEM; + view all (2018) Agalsidase alfa versus agalsidase beta for the treatment of Fabry disease: an international cohort study. Journal of Medical Genetics , 55 (5) pp. 351-358. 10.1136/jmedgenet-2017-104863. Green open access
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Arkenau, H-T; Italiano, A; Mak, G; Toulmonde, M; Baird, RD; Garcia-Corbacho, J; Plummer, R; ... Spicer, J; + view all (2018) An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours. European Journal of Cancer , 103 pp. 17-23. 10.1016/j.ejca.2018.07.134. Green open access
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Atkinson, S; Marguerat, S; Bitton, D; Bachand, F; Rodriguez-Lopez, M; Rallis, C; Lemay, J-F; ... Bähler, J; + view all (2018) Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast. RNA , 24 (9) pp. 1195-1213. 10.1261/rna.065524.118. Green open access
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Attard, G; Borre, M; Gurney, H; Loriot, Y; Andresen-Daniil, C; Kalleda, R; Trinh, P; (2018) Abiraterone Alone or in Combination With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer With Rising Prostate-Specific Antigen During Enzalutamide Treatment. Journal of Clinical Oncology , 36 (25) pp. 2639-2646. 10.1200/JCO.2018.77.9827. Green open access
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Auner, HW; Yong, KL; (2018) More convenient proteasome inhibition for improved outcomes. Lancet Oncology , 19 (7) pp. 856-858. 10.1016/S1470-2045(18)30411-X. Green open access
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Backen, AC; Lopes, A; Wasan, H; Palmer, DH; Duggan, M; Cunningham, D; Anthoney, A; ... Valle, JW; + view all (2018) Circulating biomarkers during treatment in patients with advanced biliary tract cancer receiving cediranib in the UK ABC-03 trial. British Journal of Cancer , 119 pp. 27-35. 10.1038/s41416-018-0132-8. Green open access
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Baker, A-M; Cross, W; Curtius, K; Al Bakir, I; Choi, C-HR; Davis, HL; Temko, D; ... Graham, TA; + view all (2018) Evolutionary history of human colitis-associated colorectal cancer. Gut 10.1136/gutjnl-2018-316191. Green open access
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Bakhoum, SF; Ngo, B; Laughney, AM; Cavallo, J-A; Murphy, CJ; Ly, P; Shah, P; ... Cantley, LC; + view all (2018) Chromosomal instability drives metastasis through a cytosolic DNA response. Nature , 553 (7689) pp. 467-472. 10.1038/nature25432. Green open access
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Barata, PC; De Liano, AG; Mendiratta, P; Crolley, V; Szabados, B; Morrison, L; Wood, L; ... Rini, BI; + view all (2018) The efficacy of VEGFR TKI therapy after progression on immune combination therapy in metastatic renal cell carcinoma. British Journal of Cancer , 119 (2) pp. 160-163. 10.1038/s41416-018-0104-z. Green open access
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Bazarbachi, A; Boumendil, A; Finel, H; Mohty, M; Castagna, L; Peggs, KS; Blaise, D; ... Sureda, A; + view all (2018) Brentuximab vedotin prior to allogeneic stem cell transplantation in Hodgkin lymphoma: a report from the EBMT Lymphoma Working Party. British Journal of Haematology , 181 (1) pp. 86-96. 10.1111/bjh.15152. Green open access
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Beck, M; Hughes, D; Kampmann, C; Pintos-Morell, G; Ramaswami, U; West, ML; Giugliani, R; (2018) Long-term outcomes with agalsidase alfa enzyme replacement therapy: Analysis using deconstructed composite events. Molecular Genetics and Metabolism Reports , 14 pp. 31-35. 10.1016/j.ymgmr.2017.10.008. Green open access
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Beck, S; (2018) Getting up close and personal with UK genomics and beyond. Genome Medicine , 10 (1) p. 38. 10.1186/s13073-018-0552-3. Green open access
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Beck, S; Berner, AM; Bignell, G; Bond, M; Callanan, MJ; Chervova, O; Conde, L; ... Wood, JN; + view all (2018) Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicine. BMC Medical Genomics , 11 , Article 108. 10.1186/s12920-018-0423-1. Green open access
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Belderbos, BPSI; de Wit, R; Chien, C; Mitselos, A; Hellemans, P; Jiao, J; Yu, MK; ... Saad, F; + view all (2018) An open-label, multicenter, phase Ib study investigating the effect of apalutamide on ventricular repolarization in men with castration-resistant prostate cancer. Cancer Chemotherapy and Pharmacology , 82 (3) pp. 457-468. 10.1007/s00280-018-3632-6. Green open access
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Berek, JS; Matulonis, UA; Peen, U; Ghatage, P; Mahner, S; Redondo, A; Lesoin, A; ... Mirza, MR; + view all (2018) Safety and dose modification for patients receiving niraparib. Annals of Oncology , 29 (8) pp. 1784-1792. 10.1093/annonc/mdy181. Green open access
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Berry, V; Ionides, ACW; Pontikos, N; Moghul, I; Moore, AT; Cheetham, ME; Michaelides, M; (2018) Whole-genome sequencing reveals a recurrent missense mutation in the Connexin 46 (GJA3) gene causing autosomal-dominant lamellar cataract. Eye , 32 pp. 1661-1668. 10.1038/s41433-018-0154-8. Green open access
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Biegstraaten, M; Cox, TM; Belmatoug, N; Berger, MG; Collin-Histed, T; Vom Dahl, S; Di Rocco, M; ... Hollak, CE; + view all (2018) Management goals for type 1 Gaucher disease: An expert consensus document from the European working group on Gaucher disease. Blood Cells, Molecules, and Diseases , 68 pp. 203-208. 10.1016/j.bcmd.2016.10.008. Green open access
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Bird, TG; Müller, M; Boulter, L; Vincent, DF; Ridgway, RA; Lopez-Guadamillas, E; Lu, W-Y; ... Forbes, SJ; + view all (2018) TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence. Science Translational Medicine , 10 (454) , Article eaan1230. 10.1126/scitranslmed.aan1230. Green open access
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Birley, K; Chester, K; Anderson, J; (2018) Antibody based therapy for childhood solid cancers. Current Opinion in Chemical Engineering , 19 pp. 153-162. 10.1016/j.coche.2018.01.005. Green open access
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Biswas, S; Quante, M; Leedham, S; Jansen, M; (2018) The metaplastic mosaic of Barrett's oesophagus. Virchows Archiv , 472 (1) pp. 43-54. 10.1007/s00428-018-2317-1. Green open access
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Blas, P; Tolner, B; Ward, J; Chester, K; Hoare, M; (2018) The use of a surface active agent in the protection of a fusion protein during bioprocessing. Biotechnology and Bioengineering , 115 (11) pp. 2760-2770. 10.1002/bit.26817. Green open access
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Böiers, C; Richardson, SE; Laycock, E; Zriwil, A; Turati, VA; Brown, J; Wray, JP; ... Enver, T; + view all (2018) A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1. Developmental Cell , 44 (3) pp. 362-377. 10.1016/j.devcel.2017.12.005. Green open access
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Brandner, SGP; Jaunmuktane, Z; Capper, D; Jones, DTW; Sill, M; Hovestadt, V; Schrimpf, D; ... Pfister, SM; + view all (2018) DNA methylation-based classification of central nervous system tumours. Nature. International Journal of Science , 555 pp. 469-474. 10.1038/nature26000. Green open access
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Brown, NF; Carter, TJ; Ottaviani, D; Mulholland, P; (2018) Harnessing the immune system in glioblastoma. British Journal of Cancer , 119 (10) pp. 1171-1181. 10.1038/s41416-018-0258-8. Green open access
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Brown, NF; Williams, M; Arkenau, H-T; Fleming, RA; Tolson, J; Yan, L; Zhang, J; ... Mulholland, P; + view all (2018) A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [¹¹C]GSK2256098. Neuro-Oncology , 20 (12) pp. 1634-1642. 10.1093/neuonc/noy078. Green open access
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Burnett, AK; Das Gupta, E; Knapper, S; Khwaja, A; Sweeney, M; Kjeldsen, L; Hawkins, T; ... Russell, NH; + view all (2018) The Addition Of The MTORr Inhibitor, Everolimus, To Consolidation Therapy In Acute Myeloid Leukaemia: Experience From The UK NCRI AML17 Trial. Haematologica 10.3324/haematol.2018.189514. (In press). Green open access
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Cappellini, MD; Porter, JB; Viprakasit, V; Taher, AT; (2018) A paradigm shift on beta-thalassaemia treatment: How will we manage this old disease with new therapies? Blood Reviews , 32 (4) pp. 300-311. 10.1016/j.blre.2018.02.001. Green open access
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Capper, D; Engel, NW; Stichel, D; Lechner, M; Gloess, S; Schmid, S; Koelsche, C; ... Schueller, U; + view all (2018) DNA methylation-based reclassification of olfactory neuroblastoma. Acta Neuropathologica , 136 (2) pp. 255-271. 10.1007/s00401-018-1854-7. Green open access
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Carty, F; Corbett, JM; Cunha, JPMCM; Reading, JL; Tree, TIM; Ting, AE; Stubblefield, SR; (2018) Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner. Frontiers In Immunology , 9 , Article 645. 10.3389/fimmu.2018.00645. Green open access
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Casali, PG; Bielack, S; Abecassis, N; Aro, HT; Bauer, S; Biagini, R; Bonvalot, S; ... Blay, JY; + view all (2018) Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology , 29 (4) pp. 79-95. 10.1093/annonc/mdy310. Green open access
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Catto, JWF; Khetrapal, P; Ambler, G; Sarpong, R; Khan, MS; Tan, M; Feber, A; ... Kelly, JD; + view all (2018) Robot-assisted radical cystectomy with intracorporeal urinary diversion versus open radical cystectomy (iROC): protocol for a randomised controlled trial with internal feasibility study. BMJ Open , 8 (8) , Article e020500. 10.1136/bmjopen-2017-020500. Green open access
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Catto, JWF; Khetrapal, P; Ambler, G; Sarpong, R; Potyka, I; Khan, S; Tan, M; ... Kelly, JD; + view all (2018) Multidomain Quantitative Recovery Following Radical Cystectomy for Patients Within the Robot-assisted Radical Cystectomy with Intracorporeal Urinary Diversion Versus Open Radical Cystectomy Randomised Controlled Trial: The First 30 Patients. European Urology , 74 (4) pp. 531-534. 10.1016/j.eururo.2018.05.008. Green open access
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Cereser, B; Jansen, M; Austin, E; Elia, G; Mcfarlane, T; van Deurzen, CH; Sieuwerts, AM; ... Mcdonald, SA; + view all (2018) Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells. Journal of Pathology , 244 (1) pp. 61-70. 10.1002/path.4989. Green open access
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Chakravarthy, A; Furness, A; Joshi, K; Ghorani, E; Ford, K; Ward, MJ; King, EV; ... Fenton, TR; + view all (2018) Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation. [Corrigendum]. Nature Communications , 9 , Article 4642. 10.1038/s41467-018-07155-4. Green open access
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Chakravarthy, A; Furness, A; Joshi, K; Ghorani, E; Ford, K; Ward, MJ; King, EV; ... Fenton, TR; + view all (2018) Pan-cancer deconvolution of tumour composition using DNA methylation. Nature Communications , 9 , Article 3220. 10.1038/s41467-018-05570-1. Green open access
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Chand, M; Keller, DS; Joshi, HM; Devoto, L; Rodriguez-Justo, M; Cohen, R; (2018) Feasibility of fluorescence lymph node imaging in colon cancer: FLICC. Techniques in Coloproctology , 22 (4) pp. 271-277. 10.1007/s10151-018-1773-6. Green open access
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Chapman, MA; Sive, J; Ambrose, J; Roddie, C; Counsell, N; Lach, A; Abbasian, M; ... Yong, K; + view all (2018) RNA-Seq of newly diagnosed patients in the PADIMAC study leads to a bortezomib/lenalidomide decision signature. Blood , 132 (20) pp. 2154-2165. 10.1182/blood-2018-05-849893. Green open access
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Chen, L; Esfandiari, A; Reaves, W; Vu, A; Hogarty, MD; Lunec, J; Tweddle, DA; (2018) Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours. International Journal of Oncology , 52 (3) pp. 967-977. 10.3892/ijo.2018.4261. Green open access
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Cheung, A; Opzoomer, JW; Ilieva, KM; Gazinska, P; Hoffmann, RM; Mirza, H; Marlow, R; ... Karagiannis, SN; + view all (2018) Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer. Clinical Cancer Research , 24 (20) 10.1158/1078-0432.CCR-18-0652. Green open access
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Chhetri, JB; Drousioti, E; Guerra-Assunção, JA; Herrero, J; Ooi, SKT; (2018) Generation of a Cancer Testis Antigen Mcherry Reporter Hct116 Colorectal Carcinoma Cell Line. Heliyon , 4 (10) , Article e00858. 10.1016/j.heliyon.2018.e00858. Green open access
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Chia, KH; Fukuda, T; Sofyantoro, F; Matsuda, T; Amai, T; Shiozaki, K; (2018) Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases. eLife , 6 , Article e30880. 10.7554/eLife.30880. Green open access
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Cho, S; Zammarchi, F; Williams, DG; Havenith, CE; Monks, NR; Tyrer, P; d'Hooge, F; ... van Berkel, PH; + view all (2018) Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-drug Conjugate Targeting PSMA, in Pre-clinical Models of Prostate Cancer. Molecular Cancer Therapeutics , 17 (10) 10.1158/1535-7163.MCT-17-0982. Green open access
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Claus, J; Patel, G; Autore, F; Colomba, A; Weitsman, G; Soliman, TN; Roberts, S; ... Parker, PJ; + view all (2018) Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface. eLIFE , 7 , Article e32271. 10.7554/eLife.32271. Green open access
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Cohen, H; Efthymiou, M; Gates, C; Isenberg, D; (2018) Direct Oral Anticoagulants for Thromboprophylaxis in Patients with Antiphospholipid Syndrome. Seminars in Thrombosis and Hemostasis , 44 (05) pp. 427-438. 10.1055/s-0036-1597902. Green open access
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Cohen, H; Efthymiou, M; Isenberg, DA; (2018) Use of direct oral anticoagulants in antiphospholipid syndrome. Journal of Thrombosis and Haemostasis , 16 (6) pp. 1028-1039. 10.1111/jth.14017. Green open access
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Collopy, LC; Ware, TL; Goncalves, T; Í Kongsstovu, S; Yang, Q; Amelina, H; Pinder, C; ... Tomita, K; + view all (2018) LARP7 family proteins have conserved function in telomerase assembly. Nature Communications , 9 (1) , Article 557. 10.1038/s41467-017-02296-4. Green open access
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Conibear, J; Chia, B; Ngai, Y; Bates, AT; Counsell, N; Patel, R; Eaton, D; ... Landau, D; + view all (2018) Study protocol for the SARON trial: a multicentre, randomised controlled phase III trial comparing the addition of stereotactic ablative radiotherapy and radical radiotherapy with standard chemotherapy alone for oligometastatic non-small cell lung cancer. BMJ Open , 8 (4) , Article e020690. 10.1136/bmjopen-2017-020690. Green open access
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Conteduca, V; Scarpi, E; Salvi, S; Casadio, V; Lolli, C; Gurioli, G; Schepisi, G; ... De Giorgi, U; + view all (2018) Plasma Androgen Receptor and Serum Chromogranin a in Advanced Prostate Cancer. Scientific Reports , 8 , Article 15442. 10.1038/s41598-018-33774-4. Green open access
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Cope, AP; Barnes, MR; Belson, A; Binks, M; Brockbank, S; Bonachela-Capdevila, F; Carini, C; ... RA-MAP Consortium; + view all (2018) The RA-MAP Consortium: a working model for academia-industry collaboration. Nature Reviews Rheumatology , 14 (1) pp. 53-60. 10.1038/nrrheum.2017.200. Green open access
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Coughtrey, A; Millington, A; Bennett, S; Christie, D; Hough, R; Su, M; Constantinou, M; (2018) The Effectiveness of Psychosocial Interventions for Psychological Outcomes in Paediatric Oncology: A Systematic Review. Journal of Pain and Symptom Management , 55 (3) pp. 1004-1017. 10.1016/j.jpainsymman.2017.09.022. Green open access
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Critchley, WR; Pellet-Many, C; Ringham-Terry, B; Harrison, MA; Zachary, IC; Ponnambalam, S; (2018) Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking. Cells , 7 (3) , Article 22. 10.3390/cells7030022. Green open access
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Cross, W; Kovac, M; Mustonen, V; Temko, D; Davis, H; Baker, A-M; Biswas, S; ... Tomlinson, IPM; + view all (2018) The evolutionary landscape of colorectal tumorigenesis. Nature Ecology & Evolution , 2 (10) pp. 1661-1672. 10.1038/s41559-018-0642-z. Green open access
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D'Esposito, A; Sweeney, P; Ali, M; Saleh, M; Ramasawmy, R; Roberts, T; Agliardi, G; ... Walker-Samuel, S; + view all (2018) Computational fluid dynamics with imaging of cleared tissue and of in vivo perfusion predicts drug uptake and treatment responses in tumours. Nature Biomedical Engineering , 2 pp. 773-787. 10.1038/s41551-018-0306-y. Green open access
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Davidson, SM; Riquelme, JA; Zheng, Y; Vicencio, JM; Lavandero, S; Yellon, DM; (2018) Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning. Scientific Reports , 8 , Article 15885. 10.1038/s41598-018-34357-z. Green open access
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Day, E; Jones, L; Langner, R; Stirling, LC; Hough, R; Bluebond-Langner, M; (2018) "We just follow the patients' lead": Healthcare professional perspectives on the involvement of teenagers with cancer in decision-making. Pediatric Blood and Cancer , 65 (3) , Article e26898. 10.1002/pbc.26898. Green open access
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de Boer, SM; Powell, ME; Mileshkin, L; Katsaros, D; Bessette, P; Haie-Meder, C; Ottevanger, PB; ... PORTEC study group, .; + view all (2018) Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial. The Lancet Oncology , 19 (3) pp. 295-309. 10.1016/S1470-2045(18)30079-2. Green open access
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de Carcer, G; Venkateswaran, SV; Salgueiro, L; El Bakkali, A; Somogyi, K; Rowald, K; Montanes, P; ... Sotillo, R; + view all (2018) Plk1 overexpression induces chromosomal instability and suppresses tumor development. Nature Communications , 9 , Article 3012. 10.1038/s41467-018-05429-5. Green open access
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Dhinsa, BS; DeLisa, M; Pollock, R; Flanagan, AM; Whelan, J; Gregory, J; (2018) Dedifferentiated Chondrosarcoma Demonstrating Osteosarcomatous Differentiation. Oncology Research and Treatment , 41 (7-8) pp. 456-460. 10.1159/000487803. Green open access
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Dillon, MT; Boylan, Z; Smith, D; Guevara, J; Mohammed, K; Peckitt, C; Saunders, M; ... Harrington, KJ; + view all (2018) PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours. Clinical and Translational Radiation Oncology , 12 pp. 16-20. 10.1016/j.ctro.2018.06.001. Green open access
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Diot, A; Agnew, T; Sanderson, J; Liao, C; Carver, J; Neves, RPD; Gupta, R; ... Poulton, J; + view all (2018) Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation. Frontiers in Cell and Developmental Biology , 6 , Article 103. 10.3389/fcell.2018.00103. Green open access
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Dirix, LY; Takacs, I; Jerusalem, G; Nikolinakos, P; Arkenau, H-T; Forero-Torres, A; Boccia, R; ... Hamilton, EP; + view all (2018) Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor study. Breast Cancer Research and Treatment , 167 (3) pp. 671-686. 10.1007/s10549-017-4537-5. Green open access
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Efthymiou, M; Arachchillage, DRJ; Lane, PJ; O'Keeffe, AG; McDonnell, T; Cohen, H; Mackie, IJ; (2018) Antibodies against TFPI and protein C are associated with a severe thrombotic phenotype in patients with and without antiphospholipid syndrome. Thrombosis Research , 170 pp. 60-68. 10.1016/j.thromres.2018.08.003. Green open access
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Hainsworth, EG; Shahmanesh, M; Stevenson, F; (2018) Exploring the views and experiences of HIV positive patients treated for cancer: a systematic review of the literature. AIDS Care , 30 (5) pp. 535-543. 10.1080/09540121.2017.1381332. Green open access
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Hill, AG; Findlay, M; Burge, M; Jackson, C; García Alfonso, P; Samuel, L; Ganju, V; ... Tabernero, J; + view all (2018) Phase II study of the dual EGFR/HER3 inhibitor duligotuzumab (MEHD7945A) vs. cetuximab in combination with FOLFIRI in RAS wild-type metastatic colorectal cancer. Clinical Cancer Research , 42 (10) pp. 2276-2284. 10.1158/1078-0432.CCR-17-0646. Green open access
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Holme, H; Gulati, A; Brough, R; Fleuren, EDG; Bajrami, I; Campbell, J; Chong, IY; ... Lord, CJ; + view all (2018) Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness. Scientific Reports , 8 , Article 10614. 10.1038/s41598-018-29043-z. Green open access
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Hotblack, A; Holler, A; Piapi, A; Ward, S; Strauss, HJ; Bennett, CL; (2018) Tumor-resident dendritic cells and macrophages modulate the accumulation of TCR-engineered T cells in melanoma. Molecular Therapy , 26 (6) pp. 1471-1481. 10.1016/j.ymthe.2018.03.011. Green open access
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Howie, AJ; (2018) Genetic studies of focal segmental glomerulosclerosis: a waste of scientific time? Pediatric Nephrology 10.1007/s00467-018-4161-6. (In press). Green open access
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Hudson, A; Chan, C; Woolf, D; McWilliam, A; Hiley, C; O'Connor, J; Bayman, N; ... Faivre-Finn, C; + view all (2018) Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials? Lung Cancer , 118 pp. 139-147. 10.1016/j.lungcan.2018.02.006. Green open access
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Hynds, RE; Vladimirou, E; Janes, SM; (2018) The secret lives of cancer cell lines. [Editorial comment]. Disease Models and Mechanisms , 11 , Article dmm037366. 10.1242/dmm.037366. Green open access
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Iveson, TJ; Kerr, RS; Saunders, MP; Cassidy, J; Henrik Hollander, N; Tabernero, J; Haydon, A; ... Paul, J; + view all (2018) 3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial. Lancet Oncology , 19 (4) pp. 562-578. 10.1016/S1470-2045(18)30093-7. Green open access
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Jaffer, S; Goh, P; Abbasian, M; Nathwani, AC; (2018) Mbd3 Promotes Reprogramming of Primary Human Fibroblasts. International Journal of Stem Cells , 11 (2) pp. 235-241. 10.15283/ijsc18036. Green open access
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Jansen, M; Bergman, J; (2018) Risk-stratified clinical management of superficially invasive esophageal squamous cell carcinoma after endoscopic resection: finding the sweet spot. Endoscopy , 50 (7) pp. 655-656. 10.1055/a-0596-7447. Green open access
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Jayaram, A; Wetterskog, K; Attard, G; (2018) Plasma DNA and Metastatic Castration-Resistant Prostate Cancer: The Odyssey to a Clinical Biomarker Test. Cancer Discovery , 8 (4) pp. 392-294. 10.1158/2159-8290.CD-18-0124. Green open access
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